ATE279914T1 - Oral anzuwendendes arzneimittel zur wirkstoffverabreichung im magendarmtrakt - Google Patents
Oral anzuwendendes arzneimittel zur wirkstoffverabreichung im magendarmtraktInfo
- Publication number
- ATE279914T1 ATE279914T1 AT99972918T AT99972918T ATE279914T1 AT E279914 T1 ATE279914 T1 AT E279914T1 AT 99972918 T AT99972918 T AT 99972918T AT 99972918 T AT99972918 T AT 99972918T AT E279914 T1 ATE279914 T1 AT E279914T1
- Authority
- AT
- Austria
- Prior art keywords
- layer
- drug
- gitric
- administration
- active ingredients
- Prior art date
Links
- 210000001035 gastrointestinal tract Anatomy 0.000 title abstract 2
- 239000004480 active ingredient Substances 0.000 title 1
- 229940126601 medicinal product Drugs 0.000 title 1
- 229940079593 drug Drugs 0.000 abstract 3
- 239000003814 drug Substances 0.000 abstract 3
- 238000009472 formulation Methods 0.000 abstract 3
- 239000000203 mixture Substances 0.000 abstract 3
- 239000000853 adhesive Substances 0.000 abstract 1
- 230000001070 adhesive effect Effects 0.000 abstract 1
- 238000012377 drug delivery Methods 0.000 abstract 1
- 239000004083 gastrointestinal agent Substances 0.000 abstract 1
- 229940127227 gastrointestinal drug Drugs 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4808—Preparations in capsules, e.g. of gelatin, of chocolate characterised by the form of the capsule or the structure of the filling; Capsules containing small tablets; Capsules with outer layer for immediate drug release
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4891—Coated capsules; Multilayered drug free capsule shells
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Virology (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Plant Substances (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP35396698 | 1998-11-27 | ||
| JP26643399 | 1999-09-21 | ||
| PCT/JP1999/006602 WO2000032172A1 (en) | 1998-11-27 | 1999-11-26 | An oral formulation for gastrointestinal drug delivery |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE279914T1 true ATE279914T1 (de) | 2004-11-15 |
Family
ID=26547440
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT99972918T ATE279914T1 (de) | 1998-11-27 | 1999-11-26 | Oral anzuwendendes arzneimittel zur wirkstoffverabreichung im magendarmtrakt |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US7097851B1 (de) |
| EP (1) | EP1135112B1 (de) |
| JP (1) | JP4497725B2 (de) |
| KR (1) | KR100762475B1 (de) |
| CN (1) | CN1161107C (de) |
| AT (1) | ATE279914T1 (de) |
| AU (1) | AU766293B2 (de) |
| BR (1) | BR9916871A (de) |
| CA (1) | CA2352389C (de) |
| DE (1) | DE69921353T2 (de) |
| DK (1) | DK1135112T3 (de) |
| ES (1) | ES2233106T3 (de) |
| HK (1) | HK1043545A1 (de) |
| ID (1) | ID29085A (de) |
| IL (1) | IL143356A0 (de) |
| MX (1) | MXPA01005346A (de) |
| WO (1) | WO2000032172A1 (de) |
Families Citing this family (54)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE489946T1 (de) | 2000-05-26 | 2010-12-15 | Kanji Takada | Nicht-orale zubereitung mit einer dreischicht- struktur |
| EP1390048A2 (de) * | 2001-02-16 | 2004-02-25 | Shimizu Pharmaceutical Co., Ltd. | Orale zusammensetzungen enthaltend mucopolysaccharide zur dünndarm verabreichung und deren verwendung in der behandlung von kreislaufstörungen |
| DE10120092B4 (de) * | 2001-04-25 | 2008-03-20 | Lts Lohmann Therapie-Systeme Ag | Magensaftresistente Vorrichtung zur Freisetzung von mukoadhäsiven Wirkstoffträgern und Verfahren zur Herstellung der magensaftresistenten Vorrichtung |
| AU2002319653A1 (en) * | 2001-07-20 | 2003-03-03 | Samir Mitragotri | Method for oral drug delivery |
| US6585997B2 (en) * | 2001-08-16 | 2003-07-01 | Access Pharmaceuticals, Inc. | Mucoadhesive erodible drug delivery device for controlled administration of pharmaceuticals and other active compounds |
| WO2003026699A1 (fr) * | 2001-09-26 | 2003-04-03 | Tanabe Seiyaku Co., Ltd. | Compositions medicinales favorisant l'absorption de medicaments |
| US20060034929A1 (en) * | 2001-12-27 | 2006-02-16 | Brubaker Michael J | Sustained release drug delivery devices with prefabricated permeable plugs |
| US8526466B2 (en) | 2002-07-15 | 2013-09-03 | At&T Intellectual Property I, L.P. | Apparatus and method for prioritizing communications between devices |
| US7200424B2 (en) | 2002-07-15 | 2007-04-03 | Bellsouth Intelectual Property Corporation | Systems and methods for restricting the use and movement of telephony devices |
| US8275371B2 (en) * | 2002-07-15 | 2012-09-25 | At&T Intellectual Property I, L.P. | Apparatus and method for providing communications and connection-oriented services to devices |
| US8554187B2 (en) | 2002-07-15 | 2013-10-08 | At&T Intellectual Property I, L.P. | Apparatus and method for routing communications between networks and devices |
| US8543098B2 (en) | 2002-07-15 | 2013-09-24 | At&T Intellectual Property I, L.P. | Apparatus and method for securely providing communications between devices and networks |
| TWI355276B (en) * | 2003-01-14 | 2012-01-01 | Akira Tsuji | Gastrointestinal absorption enhancer mediated by p |
| US7772188B2 (en) | 2003-01-28 | 2010-08-10 | Ironwood Pharmaceuticals, Inc. | Methods and compositions for the treatment of gastrointestinal disorders |
| JP5105578B2 (ja) | 2003-11-05 | 2012-12-26 | サーコード バイオサイエンス インコーポレイテッド | 細胞接着のモジュレーター |
| KR100638041B1 (ko) * | 2003-12-24 | 2006-10-23 | 주식회사 삼양사 | 수용성 약물의 경구투여용 나노입자 조성물 및 그의제조방법 |
| JP4606748B2 (ja) * | 2004-02-06 | 2011-01-05 | 京セラケミカル株式会社 | 固形製剤の製造方法 |
| PE20060003A1 (es) * | 2004-03-12 | 2006-03-01 | Smithkline Beecham Plc | Formulacion farmaceutica polimerica para moldear por inyeccion |
| AT502098B8 (de) | 2004-07-07 | 2007-06-15 | Albert Dr Missbichler | Diaminooxidase-hältige zusammensetzung |
| JP2008516893A (ja) * | 2004-08-27 | 2008-05-22 | スフェリックス,インク. | 多層錠剤および生体接着性剤形 |
| JP4787503B2 (ja) * | 2005-01-12 | 2011-10-05 | 京セラケミカル株式会社 | 固形製剤の製造方法 |
| JP4787507B2 (ja) * | 2005-01-24 | 2011-10-05 | 京セラケミカル株式会社 | 固形製剤及びその製造方法 |
| JP2008155067A (ja) * | 2005-04-14 | 2008-07-10 | Toray Eng Co Ltd | マイクロカプセル製造方法、マイクロカプセル製造装置、およびマイクロカプセルシート |
| US8168655B2 (en) | 2005-05-17 | 2012-05-01 | Sarcode Bioscience Inc. | Compositions and methods for treatment of eye disorders |
| DE112007000162T5 (de) * | 2006-01-19 | 2008-11-27 | Toray Engineering Co., Ltd. | Laminiertes Mikrokapselblatt und Verfahren zu deren Herstellung |
| JP2007246412A (ja) * | 2006-03-14 | 2007-09-27 | Serubakku:Kk | 消化管用経口製剤とその製造方法および消化管用経口カプセル剤 |
| US20100136123A1 (en) * | 2006-10-12 | 2010-06-03 | Toray Engineering Co., Ltd. | Microcapsule Sheet |
| EP2138168A4 (de) * | 2007-03-30 | 2012-10-10 | Lintec Corp | Mittel zur oralen verabreichung und herstellungsverfahren dafür |
| WO2008132727A2 (en) * | 2007-04-26 | 2008-11-06 | Technion Research And Development Foundation Ltd | Oral delivery of proteins and peptides |
| US8303573B2 (en) | 2007-10-17 | 2012-11-06 | The Invention Science Fund I, Llc | Medical or veterinary digestive tract utilization systems and methods |
| US20090105561A1 (en) * | 2007-10-17 | 2009-04-23 | Searete Llc, A Limited Liability Corporation Of The State Of Delaware | Medical or veterinary digestive tract utilization systems and methods |
| US8789536B2 (en) | 2007-10-17 | 2014-07-29 | The Invention Science Fund I, Llc | Medical or veterinary digestive tract utilization systems and methods |
| US8707964B2 (en) * | 2007-10-31 | 2014-04-29 | The Invention Science Fund I, Llc | Medical or veterinary digestive tract utilization systems and methods |
| MX2010004281A (es) | 2007-10-19 | 2010-09-10 | Sarcode Corp | Composiciones y metodos para el tratamiento de la retinopatia diabetica. |
| US8808276B2 (en) * | 2007-10-23 | 2014-08-19 | The Invention Science Fund I, Llc | Adaptive dispensation in a digestive tract |
| US8333754B2 (en) * | 2007-10-31 | 2012-12-18 | The Invention Science Fund I, Llc | Medical or veterinary digestive tract utilization systems and methods |
| US8109920B2 (en) * | 2007-10-31 | 2012-02-07 | The Invention Science Fund I, Llc | Medical or veterinary digestive tract utilization systems and methods |
| US20090163894A1 (en) * | 2007-10-31 | 2009-06-25 | Searete Llc, A Limited Liability Corporation Of The State Of Delaware | Medical or veterinary digestive tract utilization systems and methods |
| US8808271B2 (en) * | 2007-10-31 | 2014-08-19 | The Invention Science Fund I, Llc | Medical or veterinary digestive tract utilization systems and methods |
| US20090137866A1 (en) * | 2007-11-28 | 2009-05-28 | Searete Llc, A Limited Liability Corporation Of The State Delaware | Medical or veterinary digestive tract utilization systems and methods |
| WO2009139817A2 (en) | 2008-04-15 | 2009-11-19 | Sarcode Corporation | Crystalline pharmaceutical and methods of preparation and use thereof |
| US20120213846A1 (en) | 2008-08-15 | 2012-08-23 | Forest Laboratories Holdings Limited | Stable Solid Formulation of a GC-C Receptor Agonist Polypeptide Suitable for Oral Administration |
| US8748573B2 (en) | 2009-08-06 | 2014-06-10 | Ironwood Pharmaceuticals, Inc. | Formulations comprising linaclotide |
| US8378105B2 (en) * | 2009-10-21 | 2013-02-19 | Sarcode Bioscience Inc. | Crystalline pharmaceutical and methods of preparation and use thereof |
| US20110142889A1 (en) * | 2009-12-16 | 2011-06-16 | Nod Pharmaceuticals, Inc. | Compositions and methods for oral drug delivery |
| WO2011084618A2 (en) | 2009-12-16 | 2011-07-14 | Nod Pharmaceuticals, Inc. | Compositions and methods for oral drug delivery |
| WO2011103311A2 (en) | 2010-02-17 | 2011-08-25 | Ironwood Pharmaceuticals, Inc | Treatments for gastrointestinal disorders |
| HRP20192207T1 (hr) | 2010-08-11 | 2020-02-21 | Ironwood Pharmaceuticals, Inc. | Stabilne formulacije linaklotida |
| CN103153289B (zh) * | 2010-08-25 | 2016-08-31 | 格兰特·鲁弗斯·斯柏林二世 | 改进型肠溶活性物质给药 |
| JP5912126B2 (ja) * | 2010-11-26 | 2016-04-27 | ユニバーシティ・オブ・ジ・ウィトウォーターズランド・ヨハネスブルクUniversity Of The Witwatersrand, Johannesburg | 医薬投与形態 |
| HUE032237T2 (en) | 2011-08-17 | 2017-09-28 | Ironwood Pharmaceuticals Inc | Treatments for gastrointestinal disorders |
| WO2014018075A1 (en) | 2012-07-23 | 2014-01-30 | Crayola, Llc | Dissolvable films and methods of using the same |
| SI3715345T1 (sl) | 2012-07-25 | 2024-07-31 | Bausch + Lomb Ireland Limited | Priprava zaviralca lfa-1 |
| CN110809464A (zh) * | 2017-06-27 | 2020-02-18 | 株式会社培旺精廉宅 | 粘膜附着性口服制剂 |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4451260A (en) * | 1982-03-26 | 1984-05-29 | Minnesota Mining And Manufacturing Company | Sustained release oral medicinal delivery device |
| US4767627A (en) * | 1985-05-29 | 1988-08-30 | Merck & Co., Inc. | Drug delivery device which can be retained in the stomach for a controlled period of time |
| JPS61280423A (ja) * | 1985-06-05 | 1986-12-11 | Kiyuukiyuu Yakuhin Kogyo Kk | 口腔内粘膜貼付剤 |
| JPH07121859B2 (ja) * | 1986-03-18 | 1995-12-25 | 第一製薬株式会社 | 徐放性カプセル剤 |
| US5196202A (en) * | 1986-09-01 | 1993-03-23 | Teikoku Seiyaku Kabushiki Kaisha | Sustained release dosage form |
| US5236713A (en) | 1987-10-21 | 1993-08-17 | Teikoku Seiyaku Kabushiki Kaisha | Preparation for intermittently releasing active agent applicable to oral cavity |
| US5350741A (en) | 1988-07-30 | 1994-09-27 | Kanji Takada | Enteric formulations of physiologically active peptides and proteins |
| EP0578823B1 (de) * | 1991-04-08 | 2002-01-23 | Sumitomo Pharmaceuticals Company, Limited | Poröse feste zubereitung, die eine physiologische aktive proteinverbindung enthält |
| US5686105A (en) * | 1993-10-19 | 1997-11-11 | The Procter & Gamble Company | Pharmaceutical dosage form with multiple enteric polymer coatings for colonic delivery |
| CN1134163A (zh) * | 1993-08-19 | 1996-10-23 | 辛勒斯治疗系统公司 | 水溶性压敏粘膜粘合剂和配备该粘合剂用于放置在有粘膜衬里的体腔内的器具 |
| US5637319A (en) | 1995-03-01 | 1997-06-10 | Takada; Kanji | Controlled-release preparations |
| AUPN605795A0 (en) * | 1995-10-19 | 1995-11-09 | F.H. Faulding & Co. Limited | Analgesic pharmaceutical composition |
| US6231888B1 (en) * | 1996-01-18 | 2001-05-15 | Perio Products Ltd. | Local delivery of non steroidal anti inflammatory drugs (NSAIDS) to the colon as a treatment for colonic polyps |
| DE19646392A1 (de) * | 1996-11-11 | 1998-05-14 | Lohmann Therapie Syst Lts | Zubereitung zur Anwendung in der Mundhöhle mit einer an der Schleimhaut haftklebenden, Pharmazeutika oder Kosmetika zur dosierten Abgabe enthaltenden Schicht |
| CA2243161A1 (en) * | 1996-11-22 | 1998-05-28 | Toray Industries, Inc. | Use of interferon-beta to treat retinal edema |
| WO1998024412A2 (en) * | 1996-12-05 | 1998-06-11 | The Board Of Trustees Of The University Of Illinois | Compounds useful against diseases of the colon and methods for orally administering same |
| AU2546399A (en) * | 1998-02-10 | 1999-08-30 | Yoshitomi Pharmaceutical Industries, Ltd. | Preparations with controlled release |
-
1999
- 1999-11-26 ID IDW00200101320A patent/ID29085A/id unknown
- 1999-11-26 DE DE69921353T patent/DE69921353T2/de not_active Expired - Lifetime
- 1999-11-26 JP JP2000584868A patent/JP4497725B2/ja not_active Expired - Fee Related
- 1999-11-26 CN CNB998158186A patent/CN1161107C/zh not_active Expired - Fee Related
- 1999-11-26 DK DK99972918T patent/DK1135112T3/da active
- 1999-11-26 IL IL14335699A patent/IL143356A0/xx unknown
- 1999-11-26 BR BR9916871-5A patent/BR9916871A/pt not_active Application Discontinuation
- 1999-11-26 MX MXPA01005346A patent/MXPA01005346A/es not_active Application Discontinuation
- 1999-11-26 KR KR1020017006640A patent/KR100762475B1/ko not_active Expired - Fee Related
- 1999-11-26 CA CA002352389A patent/CA2352389C/en not_active Expired - Fee Related
- 1999-11-26 WO PCT/JP1999/006602 patent/WO2000032172A1/en not_active Ceased
- 1999-11-26 AU AU14101/00A patent/AU766293B2/en not_active Ceased
- 1999-11-26 US US09/831,901 patent/US7097851B1/en not_active Expired - Fee Related
- 1999-11-26 EP EP99972918A patent/EP1135112B1/de not_active Expired - Lifetime
- 1999-11-26 HK HK02105302.0A patent/HK1043545A1/zh unknown
- 1999-11-26 AT AT99972918T patent/ATE279914T1/de not_active IP Right Cessation
- 1999-11-26 ES ES99972918T patent/ES2233106T3/es not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| AU1410100A (en) | 2000-06-19 |
| CN1161107C (zh) | 2004-08-11 |
| CN1333680A (zh) | 2002-01-30 |
| HK1043545A1 (zh) | 2002-09-20 |
| DE69921353T2 (de) | 2005-11-10 |
| EP1135112A1 (de) | 2001-09-26 |
| DE69921353D1 (de) | 2004-11-25 |
| US7097851B1 (en) | 2006-08-29 |
| CA2352389C (en) | 2009-01-20 |
| KR100762475B1 (ko) | 2007-10-04 |
| JP4497725B2 (ja) | 2010-07-07 |
| WO2000032172A1 (en) | 2000-06-08 |
| BR9916871A (pt) | 2001-08-21 |
| KR20010086057A (ko) | 2001-09-07 |
| EP1135112B1 (de) | 2004-10-20 |
| AU766293B2 (en) | 2003-10-16 |
| CA2352389A1 (en) | 2000-06-08 |
| DK1135112T3 (da) | 2005-02-14 |
| IL143356A0 (en) | 2002-04-21 |
| ID29085A (id) | 2001-07-26 |
| ES2233106T3 (es) | 2005-06-01 |
| MXPA01005346A (es) | 2003-03-27 |
| JP2002531394A (ja) | 2002-09-24 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |