ATE280572T1 - Verabreichung von arzneistoffen im unteren verdauungstrakt - Google Patents
Verabreichung von arzneistoffen im unteren verdauungstraktInfo
- Publication number
- ATE280572T1 ATE280572T1 AT96919237T AT96919237T ATE280572T1 AT E280572 T1 ATE280572 T1 AT E280572T1 AT 96919237 T AT96919237 T AT 96919237T AT 96919237 T AT96919237 T AT 96919237T AT E280572 T1 ATE280572 T1 AT E280572T1
- Authority
- AT
- Austria
- Prior art keywords
- weight
- drug
- composition
- administration
- colon
- Prior art date
Links
- 239000003814 drug Substances 0.000 title abstract 4
- 229940079593 drug Drugs 0.000 title abstract 4
- 210000001035 gastrointestinal tract Anatomy 0.000 title 1
- 239000000203 mixture Substances 0.000 abstract 4
- 210000001072 colon Anatomy 0.000 abstract 2
- 208000019399 Colonic disease Diseases 0.000 abstract 1
- 241000196324 Embryophyta Species 0.000 abstract 1
- 239000011230 binding agent Substances 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 239000000416 hydrocolloid Substances 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 210000002438 upper gastrointestinal tract Anatomy 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
- A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/60—Salicylic acid; Derivatives thereof
- A61K31/606—Salicylic acid; Derivatives thereof having amino groups
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Urology & Nephrology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Plant Substances (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/486,974 US5656294A (en) | 1995-06-07 | 1995-06-07 | Colonic delivery of drugs |
| US08/602,611 US5811388A (en) | 1995-06-07 | 1996-02-16 | Delivery of drugs to the lower GI tract |
| PCT/US1996/009609 WO1996040078A1 (en) | 1995-06-07 | 1996-06-07 | Delivery of drugs to the lower gi tract |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE280572T1 true ATE280572T1 (de) | 2004-11-15 |
Family
ID=27048854
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT96919237T ATE280572T1 (de) | 1995-06-07 | 1996-06-07 | Verabreichung von arzneistoffen im unteren verdauungstrakt |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US5811388A (de) |
| EP (1) | EP0831791B1 (de) |
| JP (1) | JPH11507357A (de) |
| AT (1) | ATE280572T1 (de) |
| AU (1) | AU6163096A (de) |
| CA (1) | CA2224170A1 (de) |
| DE (1) | DE69633721T2 (de) |
| DK (1) | DK0831791T3 (de) |
| ES (1) | ES2231815T3 (de) |
| PT (1) | PT831791E (de) |
| WO (1) | WO1996040078A1 (de) |
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| AU1617399A (en) | 1997-12-05 | 1999-06-28 | Eli Lilly And Company | Glp-1 formulations |
| US6251863B1 (en) | 1998-09-08 | 2001-06-26 | Samuel K. Yue | Method of preventing and treating symptoms of aging and neurodegenerative dysfunctions with relaxin |
| US8293277B2 (en) * | 1998-10-01 | 2012-10-23 | Alkermes Pharma Ireland Limited | Controlled-release nanoparticulate compositions |
| US8236352B2 (en) | 1998-10-01 | 2012-08-07 | Alkermes Pharma Ireland Limited | Glipizide compositions |
| EP2266542A3 (de) * | 1998-10-01 | 2013-07-31 | Elan Pharma International Limited | Nanopartikelformulierungen mit kontrollierter Wirkstofffreisetzung |
| WO2000076478A1 (en) * | 1999-06-14 | 2000-12-21 | Cosmo S.P.A. | Controlled release and taste masking oral pharmaceutical compositions |
| US8895064B2 (en) | 1999-06-14 | 2014-11-25 | Cosmo Technologies Limited | Controlled release and taste masking oral pharmaceutical composition |
| WO2003024427A1 (en) * | 1999-12-20 | 2003-03-27 | Temple University Of The Commonwealth System Of Higher Education | Tableted oral extended release dosage form |
| US6936275B2 (en) * | 1999-12-20 | 2005-08-30 | Scolr, Inc. | Amino acid modulated extended release dosage form |
| IT1317835B1 (it) * | 2000-02-15 | 2003-07-15 | San Raffaele Centro Fond | Citochine modificate per uso nella terapia del cancro. |
| US7109303B2 (en) * | 2000-02-15 | 2006-09-19 | Fondazione Centro San Raffaele Del Monte Tabor | Modified cytokines for use in cancer therapy |
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| US7887838B2 (en) | 2002-01-18 | 2011-02-15 | Banner Pharmacaps, Inc. | Non-gelatin film and method and apparatus for producing same |
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| US20040091544A1 (en) * | 2002-11-08 | 2004-05-13 | Ruff Michael D. | Coated dibasic calcium phosphate |
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| US7816341B2 (en) * | 2003-04-14 | 2010-10-19 | Fmc Corporation | Homogeneous, thermoreversible gel containing reduced viscosity carrageenan and products made therefrom |
| US20050019294A1 (en) * | 2003-04-14 | 2005-01-27 | Fmc Corporation | Homogeneous, thermoreversible alginate films and soft capsules made therefrom |
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| MXPA05011446A (es) | 2003-04-24 | 2006-05-31 | Jagotec Ag | Tableta con liberacion retardada con geometria de nucleo definida. |
| US20050042277A1 (en) * | 2003-07-17 | 2005-02-24 | Irukulla Srinivas | Pharmaceutical compositions having a swellable coating |
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| PL1670482T5 (pl) * | 2003-09-16 | 2022-10-03 | Covis Pharma Gmbh | Zastosowanie cyklezonidu w leczeniu chorób układu oddechowego |
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| AU2011280039B2 (en) | 2010-06-30 | 2014-08-07 | Victoria Link Ltd | Methods and compositions for treatment of multiple sclerosis |
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| EP3012252A1 (de) | 2014-10-24 | 2016-04-27 | Ferring BV | Kristalline Form von elobixibat |
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| US10744070B2 (en) | 2015-06-19 | 2020-08-18 | University Of Southern California | Enteral fast access tract platform system |
| AU2016359494B2 (en) | 2015-11-24 | 2021-01-07 | Theravance Biopharma R&D Ip, Llc | Prodrugs of a JAK inhibitor compound for treatment of gastrointestinal inflammatory disease |
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| BR112019024509A2 (pt) | 2017-05-23 | 2020-06-23 | Theravance Biopharma R&D Ip, Llc | Glicuronídeo de pró-fármacos dos inibidores da janus quinase |
| CN111032019B (zh) | 2017-08-09 | 2022-07-05 | 阿尔比里奥公司 | 考来烯胺颗粒、口服考来烯胺制剂及其用途 |
| JP7710850B2 (ja) | 2017-12-29 | 2025-07-22 | ラクソン メディカル アーゲー | 薬物送達システム |
| EP3802504B1 (de) | 2018-06-05 | 2023-01-18 | Albireo AB | Benzothia(di)azepinverbindungen und ihre verwendung als gallensäuremodulatoren |
| US10793534B2 (en) | 2018-06-05 | 2020-10-06 | Albireo Ab | Benzothia(di)azepine compounds and their use as bile acid modulators |
| EP3810084A1 (de) | 2018-06-20 | 2021-04-28 | Albireo AB | Pharmazeutische formulierung von odevixibat |
| US11801226B2 (en) | 2018-06-20 | 2023-10-31 | Albireo Ab | Pharmaceutical formulation of odevixibat |
| US10722457B2 (en) | 2018-08-09 | 2020-07-28 | Albireo Ab | Oral cholestyramine formulation and use thereof |
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| US11007142B2 (en) | 2018-08-09 | 2021-05-18 | Albireo Ab | Oral cholestyramine formulation and use thereof |
| US10975045B2 (en) | 2019-02-06 | 2021-04-13 | Aibireo AB | Benzothiazepine compounds and their use as bile acid modulators |
| DK3921028T3 (da) | 2019-02-06 | 2023-01-23 | Albireo Ab | Benzothiadiazepinforbindelser og anvendelse deraf som galdesyremodulatorer |
| US10941127B2 (en) | 2019-02-06 | 2021-03-09 | Albireo Ab | Benzothiadiazepine compounds and their use as bile acid modulators |
| DK4069360T3 (da) | 2019-12-04 | 2024-02-26 | Albireo Ab | Benzothia(di)azepinforbindelser og anvendelse deraf som galdesyremodulatorer |
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| ES2972045T3 (es) | 2019-12-04 | 2024-06-10 | Albireo Ab | Compuestos de benzotia(di)azepina y su uso como moduladores del ácido biliar |
| US11014898B1 (en) | 2020-12-04 | 2021-05-25 | Albireo Ab | Benzothiazepine compounds and their use as bile acid modulators |
| CN114761018B (zh) | 2019-12-04 | 2025-12-02 | 阿尔比里奥公司 | 苯并硫杂二氮杂环庚三烯化合物及其作为胆汁酸调节剂的用途 |
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| US4999200A (en) * | 1987-12-09 | 1991-03-12 | Marion Laboratories | Psyllium tablet composition, method of manufacture and method of use |
| GB8812490D0 (en) * | 1988-05-26 | 1988-06-29 | Agricultural & Food Res | Delayed release formulations |
| US5445826A (en) * | 1988-06-28 | 1995-08-29 | Cibus Pharmaceutical, Inc. | Delivery system containing a gel-forming dietary fiber and a drug |
| US5096714A (en) * | 1988-06-28 | 1992-03-17 | Hauser-Kuhrts, Inc. | Prolonged release drug tablet formulations |
| US5128143A (en) * | 1988-09-19 | 1992-07-07 | Edward Mendell Co., Inc. | Sustained release excipient and tablet formulation |
| JP2683391B2 (ja) * | 1988-11-30 | 1997-11-26 | 日清製粉株式会社 | 小麦ふすまからのヘミセルロースを基材とする徐放性組成物 |
| US5130137A (en) * | 1989-08-09 | 1992-07-14 | The General Hospital Corporation | Continuous delivery of luteinizing hormone releasing hormone compositions in combination with sex steroid delivery for use in treating benign ovarian secretory disorders |
| GB8926639D0 (en) * | 1989-11-24 | 1990-01-17 | Agricultural & Food Res | Delayed release formulations |
| AU660147B2 (en) * | 1990-05-04 | 1995-06-15 | Perio Products Ltd. | Colonic drug delivery system |
| IL98087A (en) * | 1990-05-04 | 1996-11-14 | Perio Prod Ltd | Preparation for dispensing drugs in the colon |
| SE9002339L (sv) * | 1990-07-04 | 1992-01-05 | Kabi Pharmacia Ab | Terapeutisk komposition och foerfarande foer dess framstaellning |
| FR2667242B1 (fr) * | 1990-09-28 | 1994-11-25 | Rhone Poulenc Sante | Nouvelles formes orales a liberation prolongee avec un temps de latence au niveau stomacal amoindri. |
| EP0481240B1 (de) * | 1990-10-18 | 1996-12-11 | Basf Aktiengesellschaft | Galactomannanderivate zur Umhüllung oder Einbettung von Arzneimittelwirkstoffen |
| US5422121A (en) * | 1990-11-14 | 1995-06-06 | Rohm Gmbh | Oral dosage unit form |
| DE9015551U1 (de) * | 1990-11-14 | 1992-03-12 | Röhm GmbH, 6100 Darmstadt | Orale Arzneiform und Überzugsmittel, enthaltend ein im Colon abbaubares Polysaccarid |
| EP0676967A4 (de) * | 1992-12-30 | 1996-10-02 | Fmc Corp | Leicht verfügbarer hilfsstoff zur verzögerten freisetzung auf der basis von konjac glukomannan. |
| JPH10509981A (ja) * | 1994-12-01 | 1998-09-29 | サイバス ファーマシューティカル,インコーポレイティド | 高等植物から得られうる粉末状親水コロイドゴムを用いる持効性薬剤送出 |
| CA2205442C (en) * | 1994-12-01 | 2003-01-21 | David R. Friend | Nsaid delivery employing a powdered hydrocolloid gum obtainable from higher plants |
| US5656294A (en) * | 1995-06-07 | 1997-08-12 | Cibus Pharmaceutical, Inc. | Colonic delivery of drugs |
-
1996
- 1996-02-16 US US08/602,611 patent/US5811388A/en not_active Expired - Fee Related
- 1996-06-07 JP JP9501892A patent/JPH11507357A/ja active Pending
- 1996-06-07 ES ES96919237T patent/ES2231815T3/es not_active Expired - Lifetime
- 1996-06-07 DE DE69633721T patent/DE69633721T2/de not_active Expired - Fee Related
- 1996-06-07 PT PT96919237T patent/PT831791E/pt unknown
- 1996-06-07 CA CA002224170A patent/CA2224170A1/en not_active Abandoned
- 1996-06-07 DK DK96919237T patent/DK0831791T3/da active
- 1996-06-07 AU AU61630/96A patent/AU6163096A/en not_active Abandoned
- 1996-06-07 AT AT96919237T patent/ATE280572T1/de not_active IP Right Cessation
- 1996-06-07 EP EP96919237A patent/EP0831791B1/de not_active Expired - Lifetime
- 1996-06-07 WO PCT/US1996/009609 patent/WO1996040078A1/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| DE69633721T2 (de) | 2005-12-22 |
| PT831791E (pt) | 2005-02-28 |
| CA2224170A1 (en) | 1996-12-19 |
| EP0831791A1 (de) | 1998-04-01 |
| JPH11507357A (ja) | 1999-06-29 |
| DK0831791T3 (da) | 2005-01-31 |
| US5811388A (en) | 1998-09-22 |
| EP0831791A4 (de) | 1998-08-26 |
| EP0831791B1 (de) | 2004-10-27 |
| AU6163096A (en) | 1996-12-30 |
| DE69633721D1 (de) | 2004-12-02 |
| WO1996040078A1 (en) | 1996-12-19 |
| ES2231815T3 (es) | 2005-05-16 |
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