ATE281170T1 - Verwendung von steroiden zur behandlung von asthma und atemwegerkrankungen - Google Patents
Verwendung von steroiden zur behandlung von asthma und atemwegerkrankungenInfo
- Publication number
- ATE281170T1 ATE281170T1 AT97917945T AT97917945T ATE281170T1 AT E281170 T1 ATE281170 T1 AT E281170T1 AT 97917945 T AT97917945 T AT 97917945T AT 97917945 T AT97917945 T AT 97917945T AT E281170 T1 ATE281170 T1 AT E281170T1
- Authority
- AT
- Austria
- Prior art keywords
- steroids
- respiratory diseases
- treat asthma
- asthma
- treat
- Prior art date
Links
- 208000006673 asthma Diseases 0.000 title 1
- 201000010099 disease Diseases 0.000 title 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title 1
- 230000000241 respiratory effect Effects 0.000 title 1
- 150000003431 steroids Chemical class 0.000 title 1
- 208000036065 Airway Remodeling Diseases 0.000 abstract 1
- 229960005309 estradiol Drugs 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
- A61K31/566—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol having an oxo group in position 17, e.g. estrone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pulmonology (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Otolaryngology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Steroid Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AUPN9766A AUPN976696A0 (en) | 1996-05-09 | 1996-05-09 | Treatment of asthma and airway diseases |
| AUPN9918A AUPN991896A0 (en) | 1996-05-20 | 1996-05-20 | Treatment of asthma and airway diseases |
| PCT/AU1997/000286 WO1997042958A1 (en) | 1996-05-09 | 1997-05-09 | Treatment of asthma and airway diseases |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE281170T1 true ATE281170T1 (de) | 2004-11-15 |
Family
ID=25645169
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT97917945T ATE281170T1 (de) | 1996-05-09 | 1997-05-09 | Verwendung von steroiden zur behandlung von asthma und atemwegerkrankungen |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US5962445A (de) |
| EP (1) | EP0923376B1 (de) |
| JP (1) | JP4228116B2 (de) |
| CN (1) | CN1245982C (de) |
| AT (1) | ATE281170T1 (de) |
| CA (1) | CA2253943C (de) |
| DE (1) | DE69731473T2 (de) |
| WO (1) | WO1997042958A1 (de) |
Families Citing this family (56)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5504074A (en) * | 1993-08-06 | 1996-04-02 | Children's Medical Center Corporation | Estrogenic compounds as anti-angiogenic agents |
| US20040214807A1 (en) * | 1993-08-06 | 2004-10-28 | D'amato Robert J. | Estrogenic compounds as anti-mitotic agents |
| US6908910B2 (en) | 1993-08-06 | 2005-06-21 | The Children's Medical Center Corporation | Estrogenic compounds as anti-mitotic agents |
| US6346510B1 (en) * | 1995-10-23 | 2002-02-12 | The Children's Medical Center Corporation | Therapeutic antiangiogenic endostatin compositions |
| US6495579B1 (en) * | 1996-12-02 | 2002-12-17 | Angiotech Pharmaceuticals, Inc. | Method for treating multiple sclerosis |
| US20020002294A1 (en) * | 1997-09-24 | 2002-01-03 | D' Amato Robert J. | Estrogenic compounds as antiangiogenic agents |
| GB9923076D0 (en) | 1999-09-29 | 1999-12-01 | Phytopharm Plc | Sapogenin derivatives and their use |
| EP1124545B1 (de) | 1998-08-11 | 2004-12-15 | EntreMed, Inc. | Verwendung von 2-methoxyestradiol als fungizide |
| US6667299B1 (en) * | 2000-03-16 | 2003-12-23 | Hollis-Eden Pharmaceuticals, Inc. | Pharmaceutical compositions and treatment methods |
| GB9923078D0 (en) * | 1999-09-29 | 1999-12-01 | Phytopharm Plc | Sapogenin derivatives and their use |
| US7087592B1 (en) | 1999-08-23 | 2006-08-08 | Entre Med, Inc. | Compositions comprising purified 2-methoxyestradiol and methods of producing same |
| GB9923077D0 (en) * | 1999-09-29 | 1999-12-01 | Phytopharm Plc | Sapogenin derivatives and their use |
| GB0000228D0 (en) * | 2000-01-06 | 2000-03-01 | Phytopharm Plc | Fluoro substituted sapogenins and their use |
| US20050192258A1 (en) * | 2000-08-18 | 2005-09-01 | Agoston Gregory E. | Antiangiogenic agents |
| US6995278B2 (en) * | 2000-08-18 | 2006-02-07 | Entre Med, Inc. | Antiangiogenic agents |
| US7135581B2 (en) | 2000-08-18 | 2006-11-14 | Entremed, Inc. | Antiangiogenic agents |
| GB0107822D0 (en) * | 2001-03-28 | 2001-05-23 | Phytopharm Plc | Sapogenin derivatives their synthesis and use methods based upon their use |
| WO2003063787A2 (en) * | 2002-01-30 | 2003-08-07 | Entremed, Inc. | Non-steroidal analogs of 2-methoxyestradiol |
| CN102727501A (zh) * | 2002-03-27 | 2012-10-17 | 菲特法姆股份有限公司 | 皂角苷配基及其衍生物的用途 |
| US20050130948A1 (en) * | 2002-03-27 | 2005-06-16 | Daryl Rees | Therapeutic methods and uses of sapogenins and their derivatives |
| RU2236219C2 (ru) * | 2002-06-03 | 2004-09-20 | Чепурная Мария Михайловна | Способ лечения бронхиальной астмы у детей в приступном периоде |
| WO2004045556A2 (en) * | 2002-11-20 | 2004-06-03 | Board Of Regents, The University Of Texas System | Methods for inhibiting allergic inflammation and other responses initiated by pollens, molds, and other non-animal derived allergens |
| US20040175384A1 (en) * | 2003-12-12 | 2004-09-09 | Mohapatra Shyam S. | Protein kinase C as a target for the treatment of respiratory syncytial virus |
| KR20050104383A (ko) * | 2003-02-20 | 2005-11-02 | 유니버시티 오브 피츠버그 | 폐 고혈압의 치료를 위한 에스트라디올 대사물 |
| US20070275935A1 (en) * | 2003-05-13 | 2007-11-29 | Stewart Alastair G | Estratriene Derivatives |
| EP1633367A2 (de) | 2003-05-28 | 2006-03-15 | EntreMed, Inc. | Antiangiogene mittel |
| US8592368B2 (en) * | 2003-12-19 | 2013-11-26 | University Of South Florida | JAK/STAT inhibitors and MAPK/ERK inhibitors for RSV infection |
| CA2558014A1 (en) | 2004-03-12 | 2005-09-29 | Entremed, Inc. | Antiangiogenic agents |
| US20070004689A1 (en) * | 2004-03-12 | 2007-01-04 | Agoston Gregory E | Antiangiogenic agents |
| CA2580264A1 (en) * | 2004-09-13 | 2006-03-23 | Pr Pharmaceuticals, Inc. | Long acting injectable crystal formulations of estradiol metabolites and methods of using same |
| JP2008521822A (ja) * | 2004-11-29 | 2008-06-26 | エントレメッド インコーポレイテッド | 抗血管形成剤を投与する方法、およびそれを用いて疾病を治療する方法 |
| US20070048230A1 (en) * | 2005-08-24 | 2007-03-01 | Walter Parsadayan | Pheromone compositions and methods |
| WO2007059111A2 (en) * | 2005-11-14 | 2007-05-24 | Entremed, Inc. | Anti-angiogenic activity of 2-methoxyestradiol in combination with anti-cancer agents |
| US20070176403A1 (en) * | 2006-02-01 | 2007-08-02 | Dennis Calderone | Air adjustable seat |
| CA2646065C (en) | 2006-03-20 | 2014-01-14 | Entremed, Inc. | Disease modifying anti-arthritic activity of 2-methoxyestradiol |
| WO2008094665A1 (en) * | 2007-01-31 | 2008-08-07 | Entremed, Inc. | Method of treating amyloidosis mediated diseases |
| EP2117529A4 (de) * | 2007-02-06 | 2010-07-28 | Res Foundation Of The State Un | Verfahren zur behandlung von erkrankungen im zusammenhang mit veränderter ige-regulierung |
| US9301920B2 (en) | 2012-06-18 | 2016-04-05 | Therapeuticsmd, Inc. | Natural combination hormone replacement formulations and therapies |
| US8633178B2 (en) | 2011-11-23 | 2014-01-21 | Therapeuticsmd, Inc. | Natural combination hormone replacement formulations and therapies |
| US10806697B2 (en) | 2012-12-21 | 2020-10-20 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US20130338122A1 (en) | 2012-06-18 | 2013-12-19 | Therapeuticsmd, Inc. | Transdermal hormone replacement therapies |
| US20150196640A1 (en) | 2012-06-18 | 2015-07-16 | Therapeuticsmd, Inc. | Progesterone formulations having a desirable pk profile |
| US10806740B2 (en) | 2012-06-18 | 2020-10-20 | Therapeuticsmd, Inc. | Natural combination hormone replacement formulations and therapies |
| CN102793689A (zh) * | 2012-09-12 | 2012-11-28 | 郑州大学 | 一种抗肿瘤药物2-甲氧基雌二醇干粉吸入剂及其制备方法 |
| US11266661B2 (en) | 2012-12-21 | 2022-03-08 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US10471072B2 (en) | 2012-12-21 | 2019-11-12 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US9180091B2 (en) | 2012-12-21 | 2015-11-10 | Therapeuticsmd, Inc. | Soluble estradiol capsule for vaginal insertion |
| US10568891B2 (en) | 2012-12-21 | 2020-02-25 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US10537581B2 (en) | 2012-12-21 | 2020-01-21 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US11246875B2 (en) | 2012-12-21 | 2022-02-15 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| EP3145489A1 (de) | 2014-05-22 | 2017-03-29 | TherapeuticsMD, Inc. | Natürliche kombinierte hormonersatzformulierungen und therapien |
| US10328087B2 (en) | 2015-07-23 | 2019-06-25 | Therapeuticsmd, Inc. | Formulations for solubilizing hormones |
| WO2017173044A1 (en) | 2016-04-01 | 2017-10-05 | Therapeuticsmd Inc. | Steroid hormone compositions in medium chain oils |
| WO2017173071A1 (en) | 2016-04-01 | 2017-10-05 | Therapeuticsmd, Inc. | Steroid hormone pharmaceutical composition |
| US11633405B2 (en) | 2020-02-07 | 2023-04-25 | Therapeuticsmd, Inc. | Steroid hormone pharmaceutical formulations |
| PL244930B1 (pl) * | 2021-12-08 | 2024-04-02 | Gdanski Univ Medyczny | Zastosowanie 2-metoksyestradiolu w leczeniu mastocytozy |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3274056A (en) * | 1963-05-17 | 1966-09-20 | American Cyanamid Co | Methods for lowering blood cholesterol and compositions of alkali metal 2-methoxyestra-1, 3, 5(10)-trien-3-ol-17-one sulfate |
| US4427669A (en) * | 1982-06-28 | 1984-01-24 | The Board Of Regents Of The University Of Nebraska | Contraceptive |
| US4420428A (en) * | 1982-12-27 | 1983-12-13 | E. R. Squibb & Sons, Inc. | 16-Ketoandrostene-17-dithioketals |
| DE3344834A1 (de) * | 1983-12-08 | 1985-06-13 | Schering AG, 1000 Berlin und 4709 Bergkamen | Neue hydrocortison-und prednisolon-derivate |
| US4529548A (en) * | 1984-05-07 | 1985-07-16 | E. R. Squibb & Sons, Inc. | 17β-(substituted thio)androstenes |
| US4529547A (en) * | 1984-06-20 | 1985-07-16 | E.R. Squibb & Sons, Inc. | 17-(substituted thio)-17-(substituted dithio)androstenes |
| DK336485A (da) * | 1984-07-25 | 1986-01-26 | Hovione Int Ltd | Fremgangsmaade til fremstilling af et diisopropylaetersolvat af beclomethason-17,21-dipropionat |
| RU2028083C1 (ru) * | 1987-07-10 | 1995-02-09 | Андрюкин Алексей Алексеевич | Способ лечения стероидозависимой бронхиальной астмы |
| US5116829A (en) * | 1990-04-23 | 1992-05-26 | Kao Corporation | Steroid compounds |
| CA2111002C (en) * | 1991-06-10 | 2000-08-22 | Julianne Fassberg | Non-chlorofluorocarbon aerosol formulations |
| ATE339952T1 (de) * | 1991-06-10 | 2006-10-15 | Schering Corp | Fluorchlorkohlenwasserstofffreie aerosolformulierungen |
| CA2078804C (en) * | 1991-10-01 | 2003-02-25 | Takehiko Suzuki | Manufacture and use of novel glycosides of catechol estrogens |
| DE69311742T2 (de) * | 1992-12-24 | 1998-01-08 | Rhone Poulenc Rorer Ltd | Neue steroide |
| US5504074A (en) * | 1993-08-06 | 1996-04-02 | Children's Medical Center Corporation | Estrogenic compounds as anti-angiogenic agents |
| PE44995A1 (es) * | 1994-01-27 | 1995-12-18 | Schering Corp | Furoato de mometasona para el tratamiento de las enfermedades pulmonares y de las vias respiratorias |
| JPH08165242A (ja) * | 1994-12-09 | 1996-06-25 | Kunio Yagi | 抗動脈硬化剤 |
-
1997
- 1997-05-09 CN CNB971945055A patent/CN1245982C/zh not_active Expired - Fee Related
- 1997-05-09 CA CA002253943A patent/CA2253943C/en not_active Expired - Fee Related
- 1997-05-09 WO PCT/AU1997/000286 patent/WO1997042958A1/en not_active Ceased
- 1997-05-09 DE DE69731473T patent/DE69731473T2/de not_active Expired - Lifetime
- 1997-05-09 US US08/853,528 patent/US5962445A/en not_active Expired - Lifetime
- 1997-05-09 AT AT97917945T patent/ATE281170T1/de not_active IP Right Cessation
- 1997-05-09 JP JP53043497A patent/JP4228116B2/ja not_active Expired - Fee Related
- 1997-05-09 EP EP97917945A patent/EP0923376B1/de not_active Expired - Lifetime
-
1999
- 1999-06-11 US US09/330,918 patent/US6200966B1/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| CA2253943A1 (en) | 1997-11-20 |
| US5962445A (en) | 1999-10-05 |
| CN1218401A (zh) | 1999-06-02 |
| CA2253943C (en) | 2009-09-29 |
| JP4228116B2 (ja) | 2009-02-25 |
| CN1245982C (zh) | 2006-03-22 |
| JP2000507923A (ja) | 2000-06-27 |
| DE69731473D1 (de) | 2004-12-09 |
| WO1997042958A1 (en) | 1997-11-20 |
| US6200966B1 (en) | 2001-03-13 |
| EP0923376A4 (de) | 2001-09-26 |
| DE69731473T2 (de) | 2005-10-27 |
| EP0923376B1 (de) | 2004-11-03 |
| EP0923376A1 (de) | 1999-06-23 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |