ATE281241T1 - Verfahren zur arzneimittelaktivierung in einer schwingmühle - Google Patents

Verfahren zur arzneimittelaktivierung in einer schwingmühle

Info

Publication number
ATE281241T1
ATE281241T1 AT02754775T AT02754775T ATE281241T1 AT E281241 T1 ATE281241 T1 AT E281241T1 AT 02754775 T AT02754775 T AT 02754775T AT 02754775 T AT02754775 T AT 02754775T AT E281241 T1 ATE281241 T1 AT E281241T1
Authority
AT
Austria
Prior art keywords
drug
activation
mill
vibration mill
drug activation
Prior art date
Application number
AT02754775T
Other languages
English (en)
Inventor
Luca Dobetti
Massimo Bresciani
Original Assignee
Eurand Pharmaceuticals Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eurand Pharmaceuticals Ltd filed Critical Eurand Pharmaceuticals Ltd
Application granted granted Critical
Publication of ATE281241T1 publication Critical patent/ATE281241T1/de

Links

Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B02CRUSHING, PULVERISING, OR DISINTEGRATING; PREPARATORY TREATMENT OF GRAIN FOR MILLING
    • B02CCRUSHING, PULVERISING, OR DISINTEGRATING IN GENERAL; MILLING GRAIN
    • B02C17/00Disintegrating by tumbling mills, i.e. mills having a container charged with the material to be disintegrated with or without special disintegrating members such as pebbles or balls
    • B02C17/18Details
    • B02C17/20Disintegrating members
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B02CRUSHING, PULVERISING, OR DISINTEGRATING; PREPARATORY TREATMENT OF GRAIN FOR MILLING
    • B02CCRUSHING, PULVERISING, OR DISINTEGRATING IN GENERAL; MILLING GRAIN
    • B02C17/00Disintegrating by tumbling mills, i.e. mills having a container charged with the material to be disintegrated with or without special disintegrating members such as pebbles or balls
    • B02C17/14Mills in which the charge to be ground is turned over by movements of the container other than by rotating, e.g. by swinging, vibrating, tilting
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/146Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Food Science & Technology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Crushing And Grinding (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
AT02754775T 2001-06-29 2002-06-27 Verfahren zur arzneimittelaktivierung in einer schwingmühle ATE281241T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IE20010626 2001-06-29
PCT/EP2002/007117 WO2003002259A1 (en) 2001-06-29 2002-06-27 Process for activation of drugs in a vibrational mill

Publications (1)

Publication Number Publication Date
ATE281241T1 true ATE281241T1 (de) 2004-11-15

Family

ID=11042809

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02754775T ATE281241T1 (de) 2001-06-29 2002-06-27 Verfahren zur arzneimittelaktivierung in einer schwingmühle

Country Status (9)

Country Link
US (1) US7951399B2 (de)
EP (1) EP1406728B1 (de)
JP (1) JP4191597B2 (de)
AT (1) ATE281241T1 (de)
AU (1) AU2002321130B2 (de)
CA (1) CA2450907C (de)
DE (1) DE60201839T2 (de)
NZ (1) NZ530827A (de)
WO (1) WO2003002259A1 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20050085035A (ko) * 2002-11-18 2005-08-29 이 아이 듀폰 디 네모아 앤드 캄파니 비구형 분쇄 매체를 사용하는 매체 밀링
JP4065902B2 (ja) * 2006-04-28 2008-03-26 ライオン株式会社 造粒粒子、錠剤、及び造粒粒子の製造方法
EP2174717B1 (de) 2008-10-09 2020-04-29 Imertech Sas Schleifverfahren
WO2015071841A1 (en) 2013-11-12 2015-05-21 Druggability Technologies Holdings Limited Complexes of dabigatran and its derivatives, process for the preparation thereof and pharmaceutical compositions containing them
CN105268518B (zh) * 2014-05-29 2020-04-14 河北首鼎金属材料股份有限公司 多功能多棱磨球

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60137453A (ja) * 1983-12-26 1985-07-22 東芝セラミツクス株式会社 ミル用エレメント
US4932166A (en) * 1986-05-30 1990-06-12 The Carborundum Company Inert autogenous attrition grinding
DE4413849A1 (de) * 1994-04-21 1995-10-26 Hoechst Ag Feinverteilungsverfahren zur Herstellung von organischen Pigmenten
ES2149471T3 (es) * 1995-04-20 2000-11-01 Eurand Int Compuesto con glicolato de almidon sodico como material soporte y productos a base de dicho compuesto.
JP2000103658A (ja) * 1998-09-30 2000-04-11 Mitsubishi Materials Corp 骨材の回収方法およびその装置

Also Published As

Publication number Publication date
EP1406728A1 (de) 2004-04-14
WO2003002259A1 (en) 2003-01-09
CA2450907C (en) 2011-08-23
NZ530827A (en) 2005-06-24
JP4191597B2 (ja) 2008-12-03
EP1406728B1 (de) 2004-11-03
US7951399B2 (en) 2011-05-31
DE60201839T2 (de) 2005-10-27
JP2004530558A (ja) 2004-10-07
AU2002321130B2 (en) 2006-11-09
US20040170682A1 (en) 2004-09-02
DE60201839D1 (de) 2004-12-09
CA2450907A1 (en) 2003-01-09

Similar Documents

Publication Publication Date Title
HUP0204337A2 (hu) Biciklusos vegyületek androgén- és progeszteron-receptor modulátor hatással és ezeket tartalmazó gyógyszerkészítmények
SE0002102D0 (sv) Chemical compound
IL159474A0 (en) 1,2,4-trioxolane derivatives and pharmaceutical compositions containing the same
SE0300480D0 (sv) Novel compounds
MY140593A (en) 2-oxo-1-pyrrolidine derivatives, process for preparing them and their uses
PL310827A1 (en) Anticarcinogenous compounds, pharmaceutical agents containing them, method of obtaining such compounds and treatment methods employing them
YU22000A (sh) Biciklični inhibitori kinaze
SE0202539D0 (sv) Compounds
PL364598A1 (en) Stable polymorph of flibanserin, technical process for its preparation and the use thereof for preparing medicaments
EP1067911A4 (de) Hydrogel zusammensetzungen, geeignet zur verzögerten freisetzung von makromolekülen sowie verfahren zur herstellung derselben.
ATE386725T1 (de) Heterocyclylverbindungen
WO2003053945A3 (en) Urea derivatives and their use as vanilloid receptor antagonists
GB0109122D0 (en) Novel compounds
FR2795646B1 (fr) Article manufacture pour un usage pharmaceutique humain
WO2001098245A3 (en) Triphenyl compounds as interleukin-4 antagonists
ATE281241T1 (de) Verfahren zur arzneimittelaktivierung in einer schwingmühle
DE60205491D1 (de) Verfahren zur arzneimittelaktivierung mittels schwingmühle
PL352476A1 (en) Novel derivatives of piperazinylalkylthiopyrimidine, parmacological compositions containing tese compounds and method of obtaining active substance
EP1471035A3 (de) Auf feinteiligen Diamantteilchen basierender Träger zur Virus-Immobilizierung
BR0112258A (pt) Sistema de entrega de droga para drogas pouco solúveis em água
MXPA04005552A (es) Analogos de vitamina d.
WO2005000840A8 (en) Substituted diketopiperazines and their use as oxytocin antagonists
SE0202693D0 (sv) Compounds
SE0202692D0 (sv) Compounds
DE60032372D1 (de) Arzneizubereitungen enthaltend paclitaxel eingeschlossen in nanopartikeln von polymerischen mizellen

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification

Ref document number: 1406728

Country of ref document: EP