DK1343480T3 - Induceret faseovergangsmetode til fremstilling af mikropartikler indeholdende hydrofobe aktive midler - Google Patents

Induceret faseovergangsmetode til fremstilling af mikropartikler indeholdende hydrofobe aktive midler

Info

Publication number
DK1343480T3
DK1343480T3 DK01992358T DK01992358T DK1343480T3 DK 1343480 T3 DK1343480 T3 DK 1343480T3 DK 01992358 T DK01992358 T DK 01992358T DK 01992358 T DK01992358 T DK 01992358T DK 1343480 T3 DK1343480 T3 DK 1343480T3
Authority
DK
Denmark
Prior art keywords
active agents
phase transition
microparticles containing
induced phase
hydrophobic active
Prior art date
Application number
DK01992358T
Other languages
English (en)
Other versions
DK1343480T4 (da
Inventor
Celal Albayrak
Original Assignee
Alrise Biosystems Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
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Application filed by Alrise Biosystems Gmbh filed Critical Alrise Biosystems Gmbh
Application granted granted Critical
Publication of DK1343480T3 publication Critical patent/DK1343480T3/da
Publication of DK1343480T4 publication Critical patent/DK1343480T4/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poly(lactide-co-glycolide)

Landscapes

  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Preparation (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Biological Depolymerization Polymers (AREA)
  • Colloid Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK01992358.0T 2000-12-21 2001-12-19 Induceret faseovergangsmetode til fremstilling af mikropartikler indeholdende hydrofobe aktive midler. DK1343480T4 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US25752700P 2000-12-21 2000-12-21
US30002101P 2001-06-21 2001-06-21
PCT/US2001/050259 WO2002049620A2 (en) 2000-12-21 2001-12-19 Induced phase transition method for the production of microparticles containing hydrophobic active agents

Publications (2)

Publication Number Publication Date
DK1343480T3 true DK1343480T3 (da) 2007-08-06
DK1343480T4 DK1343480T4 (da) 2016-04-18

Family

ID=26946029

Family Applications (1)

Application Number Title Priority Date Filing Date
DK01992358.0T DK1343480T4 (da) 2000-12-21 2001-12-19 Induceret faseovergangsmetode til fremstilling af mikropartikler indeholdende hydrofobe aktive midler.

Country Status (10)

Country Link
US (2) US7252842B2 (da)
EP (2) EP1343478B1 (da)
JP (2) JP2004516263A (da)
AT (2) ATE361057T1 (da)
AU (3) AU2002232824A1 (da)
CA (2) CA2432900C (da)
DE (2) DE60130917T2 (da)
DK (1) DK1343480T4 (da)
ES (2) ES2292634T3 (da)
WO (2) WO2002049620A2 (da)

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WO2002049619A3 (en) 2002-12-05
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CA2432900A1 (en) 2002-06-27
DE60128261T2 (de) 2008-01-10
DE60128261T3 (de) 2016-06-30
WO2002049620A2 (en) 2002-06-27
DE60128261D1 (de) 2007-06-14
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ATE361057T1 (de) 2007-05-15
JP2004516263A (ja) 2004-06-03
CA2432900C (en) 2007-09-11
US7252842B2 (en) 2007-08-07
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US20030068381A1 (en) 2003-04-10
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EP1343478B1 (en) 2007-10-10
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AU2002235253A1 (en) 2002-07-01
ATE375145T1 (de) 2007-10-15
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