ATE282313T1 - ANTITUBULINANORDNUNG UND ZELLENWACHSTUMSHEMMSTOFF ßDIOXOSTATINß - Google Patents
ANTITUBULINANORDNUNG UND ZELLENWACHSTUMSHEMMSTOFF ßDIOXOSTATINßInfo
- Publication number
- ATE282313T1 ATE282313T1 AT01935147T AT01935147T ATE282313T1 AT E282313 T1 ATE282313 T1 AT E282313T1 AT 01935147 T AT01935147 T AT 01935147T AT 01935147 T AT01935147 T AT 01935147T AT E282313 T1 ATE282313 T1 AT E282313T1
- Authority
- AT
- Austria
- Prior art keywords
- ßdioxostatinß
- antitubulin
- arrangement
- cell growth
- growth inhibitor
- Prior art date
Links
- 230000010261 cell growth Effects 0.000 title 1
- 239000003966 growth inhibitor Substances 0.000 title 1
- 208000028018 Lymphocytic leukaemia Diseases 0.000 abstract 1
- 102000029749 Microtubule Human genes 0.000 abstract 1
- 108091022875 Microtubule Proteins 0.000 abstract 1
- 241001529936 Murinae Species 0.000 abstract 1
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 230000000118 anti-neoplastic effect Effects 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 210000004027 cell Anatomy 0.000 abstract 1
- 239000003112 inhibitor Substances 0.000 abstract 1
- 208000003747 lymphoid leukemia Diseases 0.000 abstract 1
- 210000004688 microtubule Anatomy 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
- C07D317/14—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D317/18—Radicals substituted by singly bound oxygen or sulfur atoms
- C07D317/22—Radicals substituted by singly bound oxygen or sulfur atoms etherified
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Ophthalmology & Optometry (AREA)
- Dermatology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Plant Substances (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US20277000P | 2000-05-09 | 2000-05-09 | |
| PCT/US2001/014790 WO2001084929A1 (en) | 2000-05-09 | 2001-05-08 | Antitubulin assembly and cell growth inhibitor denominated 'dioxostatin' |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE282313T1 true ATE282313T1 (de) | 2004-12-15 |
Family
ID=22751187
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT01935147T ATE282313T1 (de) | 2000-05-09 | 2001-05-08 | ANTITUBULINANORDNUNG UND ZELLENWACHSTUMSHEMMSTOFF ßDIOXOSTATINß |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20040122083A1 (de) |
| EP (1) | EP1283672B1 (de) |
| JP (1) | JP2004515452A (de) |
| AT (1) | ATE282313T1 (de) |
| CA (1) | CA2408220A1 (de) |
| DE (1) | DE60107234T2 (de) |
| WO (1) | WO2001084929A1 (de) |
Families Citing this family (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7244230B2 (en) * | 2002-11-08 | 2007-07-17 | Siemens Medical Solutions Usa, Inc. | Computer aided diagnostic assistance for medical imaging |
| US20050131837A1 (en) | 2003-12-15 | 2005-06-16 | Sanctis Jeanne D. | Method, system and program product for communicating e-commerce content over-the-air to mobile devices |
| US8370269B2 (en) | 2004-06-02 | 2013-02-05 | Overstock.Com, Inc. | System and methods for electronic commerce using personal and business networks |
| US7879369B2 (en) | 2007-09-18 | 2011-02-01 | Selvamedica, Llc | Combretum laurifolium Mart. extract and methods of extracting and using such extract |
| WO2009067706A1 (en) | 2007-11-21 | 2009-05-28 | Oxigene, Inc. | Method for treating hematopoietic neoplasms |
| US8583480B2 (en) | 2007-12-21 | 2013-11-12 | Overstock.Com, Inc. | System, program product, and methods for social network advertising and incentives for same |
| US9747622B1 (en) | 2009-03-24 | 2017-08-29 | Overstock.Com, Inc. | Point-and-shoot product lister |
| US9047642B2 (en) | 2011-03-24 | 2015-06-02 | Overstock.Com, Inc. | Social choice engine |
| US10546262B2 (en) | 2012-10-19 | 2020-01-28 | Overstock.Com, Inc. | Supply chain management system |
| US10949876B2 (en) | 2012-10-29 | 2021-03-16 | Overstock.Com, Inc. | System and method for management of email marketing campaigns |
| WO2014089177A2 (en) | 2012-12-04 | 2014-06-12 | Massachusetts Institute Of Technology | Compounds, conjugates and compositions of epipolythiodiketopiperazines and polythiodiketopiperazines |
| EP2972394A4 (de) | 2013-03-15 | 2016-11-02 | Sloan Kettering Inst Cancer | Hsp90-anzielende herzbildgebung und -therapie |
| US11023947B1 (en) | 2013-03-15 | 2021-06-01 | Overstock.Com, Inc. | Generating product recommendations using a blend of collaborative and content-based data |
| US11676192B1 (en) | 2013-03-15 | 2023-06-13 | Overstock.Com, Inc. | Localized sort of ranked product recommendations based on predicted user intent |
| US10810654B1 (en) | 2013-05-06 | 2020-10-20 | Overstock.Com, Inc. | System and method of mapping product attributes between different schemas |
| US9483788B2 (en) | 2013-06-25 | 2016-11-01 | Overstock.Com, Inc. | System and method for graphically building weighted search queries |
| US10929890B2 (en) | 2013-08-15 | 2021-02-23 | Overstock.Com, Inc. | System and method of personalizing online marketing campaigns |
| US10872350B1 (en) | 2013-12-06 | 2020-12-22 | Overstock.Com, Inc. | System and method for optimizing online marketing based upon relative advertisement placement |
| FR3029911B1 (fr) * | 2014-12-12 | 2018-03-09 | L'oreal | Nouveaux composes 1,2-diphenylethylene glycol pour lutter contre le vieillissement cutane et utilisation en cosmetique |
| WO2016130969A1 (en) | 2015-02-13 | 2016-08-18 | George Robert Pettit | Silstatin compounds |
| US11419934B2 (en) | 2015-08-18 | 2022-08-23 | Oncotelic Therapeutics, Inc. | Use of VDAS to enhance immunomodulating therapies against tumors |
| WO2017197045A1 (en) | 2016-05-11 | 2017-11-16 | Movassaghi Mohammad | Convergent and enantioselective total synthesis of communesin analogs |
| US10534845B2 (en) | 2016-05-11 | 2020-01-14 | Overstock.Com, Inc. | System and method for optimizing electronic document layouts |
| US10970769B2 (en) | 2017-03-02 | 2021-04-06 | Overstock.Com, Inc. | Method and system for optimizing website searching with user pathing |
| US11932650B2 (en) | 2017-05-11 | 2024-03-19 | Massachusetts Institute Of Technology | Potent agelastatin derivatives as modulators for cancer invasion and metastasis |
| US10640508B2 (en) | 2017-10-13 | 2020-05-05 | Massachusetts Institute Of Technology | Diazene directed modular synthesis of compounds with quaternary carbon centers |
| WO2019094709A1 (en) | 2017-11-09 | 2019-05-16 | Pettit George R | Betulastatin compounds |
| US11514493B1 (en) | 2019-03-25 | 2022-11-29 | Overstock.Com, Inc. | System and method for conversational commerce online |
| US11205179B1 (en) | 2019-04-26 | 2021-12-21 | Overstock.Com, Inc. | System, method, and program product for recognizing and rejecting fraudulent purchase attempts in e-commerce |
| US11535634B2 (en) | 2019-06-05 | 2022-12-27 | Massachusetts Institute Of Technology | Compounds, conjugates, and compositions of epipolythiodiketopiperazines and polythiodiketopiperazines and uses thereof |
| US11734368B1 (en) | 2019-09-26 | 2023-08-22 | Overstock.Com, Inc. | System and method for creating a consistent personalized web experience across multiple platforms and channels |
| WO2022182415A1 (en) | 2021-02-24 | 2022-09-01 | Massachusetts Institute Of Technology | Himastatin derivatives, and processes of preparation thereof, and uses thereof |
| CN113511962A (zh) * | 2021-06-30 | 2021-10-19 | 上海应用技术大学 | 一种氟代乙氧基毛兰素及其制备方法与应用 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW325458B (en) * | 1993-09-08 | 1998-01-21 | Ajinomoto Kk | Stilbene derivatives and pharmaceutical compositions comprising the same for anti-cancer |
| EP1214298B1 (de) * | 1999-09-17 | 2012-05-30 | Baylor University | Indol-enthaltende und combrestatin-anverwandte anti-mitotische und die tubulin-polymerisation hemmende wirkstoffe |
-
2001
- 2001-05-08 US US10/275,789 patent/US20040122083A1/en not_active Abandoned
- 2001-05-08 EP EP01935147A patent/EP1283672B1/de not_active Expired - Lifetime
- 2001-05-08 JP JP2001581605A patent/JP2004515452A/ja active Pending
- 2001-05-08 DE DE60107234T patent/DE60107234T2/de not_active Expired - Fee Related
- 2001-05-08 CA CA002408220A patent/CA2408220A1/en not_active Abandoned
- 2001-05-08 AT AT01935147T patent/ATE282313T1/de not_active IP Right Cessation
- 2001-05-08 WO PCT/US2001/014790 patent/WO2001084929A1/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| WO2001084929A1 (en) | 2001-11-15 |
| US20040122083A1 (en) | 2004-06-24 |
| EP1283672A4 (de) | 2003-06-04 |
| DE60107234T2 (de) | 2005-10-27 |
| EP1283672B1 (de) | 2004-11-17 |
| DE60107234D1 (de) | 2004-12-23 |
| EP1283672A1 (de) | 2003-02-19 |
| CA2408220A1 (en) | 2001-11-15 |
| JP2004515452A (ja) | 2004-05-27 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |