ATE282616T1 - Verfahren zur herstellung von wasserfreien mirtazapin-kristallen. - Google Patents
Verfahren zur herstellung von wasserfreien mirtazapin-kristallen.Info
- Publication number
- ATE282616T1 ATE282616T1 AT01111102T AT01111102T ATE282616T1 AT E282616 T1 ATE282616 T1 AT E282616T1 AT 01111102 T AT01111102 T AT 01111102T AT 01111102 T AT01111102 T AT 01111102T AT E282616 T1 ATE282616 T1 AT E282616T1
- Authority
- AT
- Austria
- Prior art keywords
- anhydrous mirtazapine
- mirtazapine crystals
- producing anhydrous
- substantially free
- crystals
- Prior art date
Links
- 239000013078 crystal Substances 0.000 title abstract 3
- RONZAEMNMFQXRA-UHFFFAOYSA-N mirtazapine Chemical compound C1C2=CC=CN=C2N2CCN(C)CC2C2=CC=CC=C21 RONZAEMNMFQXRA-UHFFFAOYSA-N 0.000 title abstract 3
- 229960001785 mirtazapine Drugs 0.000 title abstract 3
- 238000004519 manufacturing process Methods 0.000 title 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 239000002245 particle Substances 0.000 abstract 1
- 239000013557 residual solvent Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
- C07D471/14—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2000359891 | 2000-11-27 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE282616T1 true ATE282616T1 (de) | 2004-12-15 |
Family
ID=18831578
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT01111102T ATE282616T1 (de) | 2000-11-27 | 2001-05-08 | Verfahren zur herstellung von wasserfreien mirtazapin-kristallen. |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US6660730B2 (de) |
| EP (1) | EP1209159B1 (de) |
| AT (1) | ATE282616T1 (de) |
| AU (1) | AU781974B2 (de) |
| CA (1) | CA2346195A1 (de) |
| DE (1) | DE60107189T2 (de) |
| DK (1) | DK1209159T3 (de) |
| ES (1) | ES2231340T3 (de) |
| IL (1) | IL146548A (de) |
| PT (1) | PT1209159E (de) |
| SI (1) | SI1209159T1 (de) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2001038329A1 (en) * | 1999-11-24 | 2001-05-31 | Sumika Fine Chemicals Co., Ltd. | Anhydrous mirtazapine crystals and process for producing the same |
| US7838029B1 (en) * | 2003-07-31 | 2010-11-23 | Watson Laboratories, Inc. | Mirtazapine solid dosage forms |
| EP1689371A2 (de) * | 2003-11-25 | 2006-08-16 | Aurobindo Pharma Limited | Pharmazeutische zusammensetzung mirtazapine enthaltend |
| JP5192707B2 (ja) | 2007-03-22 | 2013-05-08 | 住友化学株式会社 | ミルタザピンの製造方法 |
| WO2016138357A1 (en) | 2015-02-27 | 2016-09-01 | Kindred Biosciences, Inc. | Stimulation of appetite, management of weight loss, and treatment of anorexia in dogs and cats |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL189199C (nl) | 1975-04-05 | 1993-02-01 | Akzo Nv | Werkwijze ter bereiding van farmaceutische preparaten met werking op het centraal zenuwstelsel op basis van benz(aryl)azepinederivaten, de verkregen gevormde farmaceutische preparaten, alsmede werkwijze ter bereiding van de toe te passen benz(aryl)azepinederivaten. |
| CA2368815A1 (en) * | 1999-04-19 | 2000-10-26 | Claude Singer | Novel synthesis and crystallization of piperazine ring-containing compounds |
-
2001
- 2001-04-27 US US09/842,871 patent/US6660730B2/en not_active Expired - Fee Related
- 2001-04-30 AU AU40301/01A patent/AU781974B2/en not_active Ceased
- 2001-05-02 CA CA002346195A patent/CA2346195A1/en not_active Abandoned
- 2001-05-08 SI SI200130260T patent/SI1209159T1/xx unknown
- 2001-05-08 DK DK01111102T patent/DK1209159T3/da active
- 2001-05-08 ES ES01111102T patent/ES2231340T3/es not_active Expired - Lifetime
- 2001-05-08 AT AT01111102T patent/ATE282616T1/de active
- 2001-05-08 EP EP01111102A patent/EP1209159B1/de not_active Expired - Lifetime
- 2001-05-08 DE DE60107189T patent/DE60107189T2/de not_active Expired - Lifetime
- 2001-05-08 PT PT01111102T patent/PT1209159E/pt unknown
- 2001-11-19 IL IL146548A patent/IL146548A/en not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| SI1209159T1 (en) | 2005-04-30 |
| AU781974B2 (en) | 2005-06-23 |
| ES2231340T3 (es) | 2005-05-16 |
| DK1209159T3 (da) | 2005-01-24 |
| US20020065413A1 (en) | 2002-05-30 |
| DE60107189D1 (de) | 2004-12-23 |
| DE60107189T2 (de) | 2005-06-30 |
| EP1209159A2 (de) | 2002-05-29 |
| US6660730B2 (en) | 2003-12-09 |
| IL146548A0 (en) | 2002-07-25 |
| AU4030101A (en) | 2002-06-06 |
| EP1209159B1 (de) | 2004-11-17 |
| EP1209159A3 (de) | 2003-03-05 |
| CA2346195A1 (en) | 2002-05-27 |
| PT1209159E (pt) | 2005-01-31 |
| IL146548A (en) | 2007-08-19 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
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