ATE298746T1 - Verfahren zur herstellung von substituierten benzimidazolverbindungen - Google Patents

Verfahren zur herstellung von substituierten benzimidazolverbindungen

Info

Publication number: ATE298746T1
Authority: AT; Austria
Prior art keywords: substituted benzimidazole; benzimidazole compounds; producing substituted; compounds; producing
Prior art date: 2000-04-11

Application number

AT01929529T

Other languages

English (en)

Inventor

Stephen Freeman

Original Assignee

Glaxo Group Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-04-11

Filing date

2001-04-10

Publication date

2005-07-15

2001-04-10 Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd

2005-07-15 Application granted granted Critical

2005-07-15 Publication of ATE298746T1 publication Critical patent/ATE298746T1/de

Links

150000001556 benzimidazoles Chemical class 0.000 title abstract 2
238000004519 manufacturing process Methods 0.000 title 1
KEZMBKQTCPNSOF-UHFFFAOYSA-N 2-bromo-5,6-dichloro-1h-benzimidazole Chemical compound C1=C(Cl)C(Cl)=CC2=C1NC(Br)=N2 KEZMBKQTCPNSOF-UHFFFAOYSA-N 0.000 abstract 1
230000000840 anti-viral effect Effects 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/052—Imidazole radicals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Molecular Biology (AREA)
Genetics & Genomics (AREA)
Biotechnology (AREA)
Biochemistry (AREA)
Engineering & Computer Science (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Animal Behavior & Ethology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Virology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Saccharide Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

AT01929529T 2000-04-11 2001-04-10 Verfahren zur herstellung von substituierten benzimidazolverbindungen ATE298746T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GBGB0008939.1A GB0008939D0 (en)	2000-04-11	2000-04-11	Process for preparing substituted benzimidazole compounds
PCT/EP2001/004080 WO2001077083A1 (en)	2000-04-11	2001-04-10	Process for preparing substituted benzimidazole compounds

Publications (1)

Publication Number	Publication Date
ATE298746T1 true ATE298746T1 (de)	2005-07-15

Family

ID=9889715

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT01929529T ATE298746T1 (de)	2000-04-11	2001-04-10	Verfahren zur herstellung von substituierten benzimidazolverbindungen

Country Status (9)

Country	Link
US (4)	US7101994B2 (de)
EP (2)	EP1272473B1 (de)
JP (2)	JP4841793B2 (de)
AT (1)	ATE298746T1 (de)
AU (1)	AU2001256272A1 (de)
DE (1)	DE60111732T2 (de)
ES (1)	ES2243488T3 (de)
GB (1)	GB0008939D0 (de)
WO (1)	WO2001077083A1 (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP1144387A1 (de)	1998-12-04	2001-10-17	Neurosearch A/S	Benzimidazolon-, benzoxazolon- oder benzothiazolon-derivate als ionenkanal modulierende mittel
EP2319838A1 (de) *	2002-06-07	2011-05-11	Cortical Pty Ltd	Therapeutische Moleküle und Verfahren 1
JP5193876B2 (ja) *	2005-12-02	2013-05-08	バイエル・ヘルスケア・エルエルシー	オーロラキナーゼの阻害により癌を処置するために有用なピロロトリアジン誘導体
US7655004B2 (en)	2007-02-15	2010-02-02	Ethicon Endo-Surgery, Inc.	Electroporation ablation apparatus, system, and method
US8888792B2 (en)	2008-07-14	2014-11-18	Ethicon Endo-Surgery, Inc.	Tissue apposition clip application devices and methods
US8157834B2 (en)	2008-11-25	2012-04-17	Ethicon Endo-Surgery, Inc.	Rotational coupling device for surgical instrument with flexible actuators
US20110098704A1 (en)	2009-10-28	2011-04-28	Ethicon Endo-Surgery, Inc.	Electrical ablation devices
US8546344B2 (en)	2010-10-28	2013-10-01	Viropharma Incorporated	Crystalline phases of 5,6-dichloro-2-(isopropylamino)-1-β-L-ribofuranosyl)-1H-benzimidazole
US9254169B2 (en)	2011-02-28	2016-02-09	Ethicon Endo-Surgery, Inc.	Electrical ablation devices and methods
US9233241B2 (en)	2011-02-28	2016-01-12	Ethicon Endo-Surgery, Inc.	Electrical ablation devices and methods
CN102952104A (zh) *	2011-08-17	2013-03-06	黑龙江省松花江药业有限公司	一种呋喃类化合物
US9427255B2 (en)	2012-05-14	2016-08-30	Ethicon Endo-Surgery, Inc.	Apparatus for introducing a steerable camera assembly into a patient
US9545290B2 (en)	2012-07-30	2017-01-17	Ethicon Endo-Surgery, Inc.	Needle probe guide
US10314649B2 (en)	2012-08-02	2019-06-11	Ethicon Endo-Surgery, Inc.	Flexible expandable electrode and method of intraluminal delivery of pulsed power
US9277957B2 (en)	2012-08-15	2016-03-08	Ethicon Endo-Surgery, Inc.	Electrosurgical devices and methods
US10098527B2 (en)	2013-02-27	2018-10-16	Ethidcon Endo-Surgery, Inc.	System for performing a minimally invasive surgical procedure
IL319923A (en)	2022-10-12	2025-05-01	Takeda Pharmaceuticals Co	Maribavir preparation method

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE3839743A1 (de)	1988-11-25	1990-05-31	Hoechst Ag	Verfahren zur herstellung von benzimidazolonen
EP0480939B1 (de) *	1989-06-09	1995-01-25	The Upjohn Company	Heterozyklische amine mit zns-wirksamkeit
US5248672A (en) *	1990-11-01	1993-09-28	The Regents Of The University Of Michigan	Polysubstituted benzimidazole nucleosides as antiviral agents
GB9205071D0 (en)	1992-03-09	1992-04-22	Wellcome Found	Therapeutic nucleosides
GB9413724D0 (en) *	1994-07-07	1994-08-24	Wellcome Found	Therapeutic nucleosides
JPH10505092A (ja)	1994-09-09	1998-05-19	ザ・ウエルカム・ファンデーション・リミテッド	環状炭素に連結される置換されたベンズイミダゾール塩基を含む抗ウイルス性ヌクレオシドアナログ
WO1997007125A1 (en)	1995-08-18	1997-02-27	The Regents Of The University Of Michigan	5'-substituted-ribofuranosyl benzimidazoles as antiviral agents
GB9600142D0 (en)	1996-01-05	1996-03-06	Wellcome Found	Chemical compounds
GB9600143D0 (en)	1996-01-05	1996-03-06	Wellcome Found	Therapeutic compounds
US5840743A (en)	1996-01-23	1998-11-24	The Regents Of The University Of Michigan	Modified benzimidazole nucleosides as antiviral agents
US6413938B1 (en)	1997-02-13	2002-07-02	The Regents Of The University Of Michigan	Benzimidazole derivatives for the treatment of viral infections
ID24054A (id) *	1997-06-10	2000-07-06	Glaxo Group Ltd Glaxo	Turunan turunan benzimidazol
AU744176B2 (en)	1997-07-30	2002-02-14	Glaxo Group Limited	Lyxofuranosyl benzimidazoles as antiviral agents
GB9807355D0 (en)	1998-04-07	1998-06-03	Glaxo Group Ltd	Antiviral compound
GB9807354D0 (en)	1998-04-07	1998-06-03	Glaxo Group Ltd	Antiviral compound
GB9815696D0 (en)	1998-07-20	1998-09-16	Pfizer Ltd	Heterocyclics

2000
- 2000-04-11 GB GBGB0008939.1A patent/GB0008939D0/en not_active Ceased
2001
- 2001-04-10 EP EP01929529A patent/EP1272473B1/de not_active Expired - Lifetime
- 2001-04-10 AU AU2001256272A patent/AU2001256272A1/en not_active Abandoned
- 2001-04-10 ES ES01929529T patent/ES2243488T3/es not_active Expired - Lifetime
- 2001-04-10 AT AT01929529T patent/ATE298746T1/de not_active IP Right Cessation
- 2001-04-10 EP EP05013909A patent/EP1584620A1/de not_active Withdrawn
- 2001-04-10 WO PCT/EP2001/004080 patent/WO2001077083A1/en not_active Ceased
- 2001-04-10 JP JP2001575558A patent/JP4841793B2/ja not_active Expired - Lifetime
- 2001-04-10 DE DE60111732T patent/DE60111732T2/de not_active Expired - Lifetime
- 2001-04-10 US US10/240,906 patent/US7101994B2/en not_active Expired - Lifetime
2005
- 2005-07-26 US US11/190,581 patent/US7375235B2/en not_active Expired - Lifetime
2008
- 2008-04-11 US US12/101,226 patent/US7514568B2/en not_active Expired - Lifetime
2009
- 2009-03-26 US US12/411,589 patent/US7858773B2/en not_active Expired - Fee Related
2011
- 2011-04-21 JP JP2011095407A patent/JP5192061B2/ja not_active Expired - Lifetime

Also Published As

Publication number	Publication date
US20090187015A1 (en)	2009-07-23
JP4841793B2 (ja)	2011-12-21
EP1584620A1 (de)	2005-10-12
WO2001077083A1 (en)	2001-10-18
DE60111732T2 (de)	2006-05-04
EP1272473B1 (de)	2005-06-29
GB0008939D0 (en)	2000-05-31
US7514568B2 (en)	2009-04-07
US20080188668A1 (en)	2008-08-07
US7858773B2 (en)	2010-12-28
JP5192061B2 (ja)	2013-05-08
US20050261211A1 (en)	2005-11-24
JP2003530385A (ja)	2003-10-14
US20030191127A1 (en)	2003-10-09
US7375235B2 (en)	2008-05-20
DE60111732D1 (de)	2005-08-04
ES2243488T3 (es)	2005-12-01
JP2011173906A (ja)	2011-09-08
EP1272473A1 (de)	2003-01-08
US7101994B2 (en)	2006-09-05
AU2001256272A1 (en)	2001-10-23

Legal Events

Date	Code	Title	Description
2005-12-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties

Publication	Publication Date	Title
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ATE286011T1 (de)	2005-01-15	Verfahren zur herstellung von 1-octen
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ATE358172T1 (de)	2007-04-15	Verfahren zur herstellung von olefinen.
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