ATE283036T1 - Pharmazeutische zusammensetzung mit gesteuerter freigabe enthaltend midodrin und/oder desglymidodrin - Google Patents
Pharmazeutische zusammensetzung mit gesteuerter freigabe enthaltend midodrin und/oder desglymidodrinInfo
- Publication number
- ATE283036T1 ATE283036T1 AT01919228T AT01919228T ATE283036T1 AT E283036 T1 ATE283036 T1 AT E283036T1 AT 01919228 T AT01919228 T AT 01919228T AT 01919228 T AT01919228 T AT 01919228T AT E283036 T1 ATE283036 T1 AT E283036T1
- Authority
- AT
- Austria
- Prior art keywords
- desglymidodrine
- midodrine
- controlled release
- release pharmaceutical
- pharmaceutical composition
- Prior art date
Links
- VFRCNXKYZVQYLX-UHFFFAOYSA-N deglymidodrine Chemical compound COC1=CC=C(OC)C(C(O)CN)=C1 VFRCNXKYZVQYLX-UHFFFAOYSA-N 0.000 title abstract 6
- 229960001094 midodrine Drugs 0.000 title abstract 4
- 238000013270 controlled release Methods 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- PTKSEFOSCHHMPD-UHFFFAOYSA-N midodrine Chemical compound COC1=CC=C(OC)C(C(O)CNC(=O)CN)=C1 PTKSEFOSCHHMPD-UHFFFAOYSA-N 0.000 title 1
- PTKSEFOSCHHMPD-SNVBAGLBSA-N 2-amino-n-[(2s)-2-(2,5-dimethoxyphenyl)-2-hydroxyethyl]acetamide Chemical compound COC1=CC=C(OC)C([C@H](O)CNC(=O)CN)=C1 PTKSEFOSCHHMPD-SNVBAGLBSA-N 0.000 abstract 3
- 239000002207 metabolite Substances 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- 230000036470 plasma concentration Effects 0.000 abstract 2
- 206010046543 Urinary incontinence Diseases 0.000 abstract 1
- 238000010521 absorption reaction Methods 0.000 abstract 1
- 210000001035 gastrointestinal tract Anatomy 0.000 abstract 1
- 230000002746 orthostatic effect Effects 0.000 abstract 1
- 230000002035 prolonged effect Effects 0.000 abstract 1
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
- A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2886—Dragees; Coated pills or tablets, e.g. with film or compression coating having two or more different drug-free coatings; Tablets of the type inert core-drug layer-inactive layer
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
- A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Nanotechnology (AREA)
- Molecular Biology (AREA)
- Medical Informatics (AREA)
- General Engineering & Computer Science (AREA)
- Crystallography & Structural Chemistry (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Urology & Nephrology (AREA)
- Emergency Medicine (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DKPA200000549 | 2000-03-31 | ||
| US20378300P | 2000-05-12 | 2000-05-12 | |
| PCT/DK2001/000213 WO2001074334A1 (en) | 2000-03-31 | 2001-03-29 | Controlled release pharmaceutical composition containing midodrine and/or desglymidodrine |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE283036T1 true ATE283036T1 (de) | 2004-12-15 |
Family
ID=26068806
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT01919228T ATE283036T1 (de) | 2000-03-31 | 2001-03-29 | Pharmazeutische zusammensetzung mit gesteuerter freigabe enthaltend midodrin und/oder desglymidodrin |
Country Status (10)
| Country | Link |
|---|---|
| EP (1) | EP1267841B1 (de) |
| JP (1) | JP2003528909A (de) |
| CN (1) | CN1422150A (de) |
| AT (1) | ATE283036T1 (de) |
| AU (1) | AU2001246388A1 (de) |
| CA (1) | CA2403886A1 (de) |
| DE (1) | DE60107399D1 (de) |
| EE (1) | EE200200556A (de) |
| NO (1) | NO20024673L (de) |
| WO (1) | WO2001074334A1 (de) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2409950A1 (en) * | 2000-05-26 | 2001-11-29 | Nycomed Austria Gmbh | Pharmaceutical compositions comprising desglymidodrine as an active drug substance |
| CA3018328A1 (en) | 2014-10-31 | 2016-04-30 | Purdue Pharma | Methods and compositions particularly for treatment of attention deficit disorder |
| WO2018064490A1 (en) * | 2016-09-30 | 2018-04-05 | Xenamed Corporation | Compositions of midodrine and methods of using the same |
| US20190240172A1 (en) * | 2016-10-21 | 2019-08-08 | Cellvertics Co., Ltd. | Pharmaceutical composition for preventing or treating diabetes and/or hyperlipidemia comprising midodrine or pharmaceutically acceptable salt thereof as active ingredient |
| EP3582765B1 (de) | 2017-10-10 | 2021-04-28 | Vertice Pharma, LLC | Orale midodrinhydrochloridlösung und verwendungen davon |
| WO2019126770A1 (en) | 2017-12-22 | 2019-06-27 | Xenamed Corp. | Extended release midodrine hydrochloride compositions and methods of use |
| US10722473B2 (en) | 2018-11-19 | 2020-07-28 | Purdue Pharma L.P. | Methods and compositions particularly for treatment of attention deficit disorder |
| KR102151051B1 (ko) * | 2019-01-10 | 2020-09-02 | 고려대학교 산학협력단 | 당뇨병성 백내장 치료 또는 예방용 조성물 |
| WO2022157633A1 (en) * | 2021-01-20 | 2022-07-28 | Cadila Healthcare Limited | Enantiomerically pure desglymidodrine and process for preparation thereof |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3417576A1 (de) * | 1984-05-11 | 1985-11-14 | Lentia GmbH Chem. u. pharm. Erzeugnisse - Industriebedarf, 8000 München | Retardformen des alpha-(2,5-dimethoxy-phenyl)-ss-glycinamidoaethanols und verfahren zu ihrer herstellung |
| AT383270B (de) * | 1984-05-15 | 1987-06-10 | Chemie Linz Ag | Verfahren zur herstellung von oralen retardformen des alpha-(2,5-dimethoxy-phenyl)-betaglycinamido|thanols |
| DE59003337D1 (de) * | 1989-10-16 | 1993-12-09 | Danubia Petrochem Polymere | Pressling mit retardierter Wirkstofffreisetzung. |
-
2001
- 2001-03-29 WO PCT/DK2001/000213 patent/WO2001074334A1/en not_active Ceased
- 2001-03-29 CN CN01807541A patent/CN1422150A/zh active Pending
- 2001-03-29 AT AT01919228T patent/ATE283036T1/de not_active IP Right Cessation
- 2001-03-29 DE DE60107399T patent/DE60107399D1/de not_active Expired - Lifetime
- 2001-03-29 EE EEP200200556A patent/EE200200556A/xx unknown
- 2001-03-29 AU AU2001246388A patent/AU2001246388A1/en not_active Abandoned
- 2001-03-29 CA CA002403886A patent/CA2403886A1/en not_active Abandoned
- 2001-03-29 JP JP2001572079A patent/JP2003528909A/ja active Pending
- 2001-03-29 EP EP01919228A patent/EP1267841B1/de not_active Expired - Lifetime
-
2002
- 2002-09-30 NO NO20024673A patent/NO20024673L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| CN1422150A (zh) | 2003-06-04 |
| NO20024673D0 (no) | 2002-09-30 |
| EP1267841A1 (de) | 2003-01-02 |
| JP2003528909A (ja) | 2003-09-30 |
| CA2403886A1 (en) | 2001-10-11 |
| DE60107399D1 (de) | 2004-12-30 |
| WO2001074334A1 (en) | 2001-10-11 |
| EP1267841B1 (de) | 2004-11-24 |
| EE200200556A (et) | 2004-04-15 |
| NO20024673L (no) | 2002-11-27 |
| AU2001246388A1 (en) | 2001-10-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |