UA90893C2 - Пероральная дозированная форма производных гемцитабина - Google Patents

Пероральная дозированная форма производных гемцитабина

Info

Publication number
UA90893C2
UA90893C2 UAA200711518A UAA200711518A UA90893C2 UA 90893 C2 UA90893 C2 UA 90893C2 UA A200711518 A UAA200711518 A UA A200711518A UA A200711518 A UAA200711518 A UA A200711518A UA 90893 C2 UA90893 C2 UA 90893C2
Authority
UA
Ukraine
Prior art keywords
oral dosage
dosage forms
gemcitabine
derivatives
gemcitabine derivatives
Prior art date
Application number
UAA200711518A
Other languages
English (en)
Ukrainian (uk)
Inventor
Финн МИРЕН
Марит Лиланд САНДВОЛЬД
Оле Хенрик ЭРИКСЕН
Original Assignee
Клавис Фарма Ас
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Клавис Фарма Ас filed Critical Клавис Фарма Ас
Publication of UA90893C2 publication Critical patent/UA90893C2/ru

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A61K31/7068—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)

Abstract

Изобретение касается пероральных дозированных форм производных определенных длинноцепочных насыщенных и мононенасыщенных жирных кислот и 2',2'-дифтордеоксицитидина (гемцитабина). В частности, изобретение касается применения указанных производных гемцитабина или их фармацевтически приемлемой соли для приготовления пероральной дозированной формы для улучшения комплаентности при лечении рака.
UAA200711518A 2005-03-18 2006-03-07 Пероральная дозированная форма производных гемцитабина UA90893C2 (ru)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
NO20051467A NO322682B1 (no) 2005-03-18 2005-03-18 Anvendelse av gemcitabinderivater for fremstilling av orale doseringsformer ved kreftbehandling, samt slike orale doseringsformer

Publications (1)

Publication Number Publication Date
UA90893C2 true UA90893C2 (ru) 2010-06-10

Family

ID=35267108

Family Applications (1)

Application Number Title Priority Date Filing Date
UAA200711518A UA90893C2 (ru) 2005-03-18 2006-03-07 Пероральная дозированная форма производных гемцитабина

Country Status (13)

Country Link
US (1) US20080280851A1 (ru)
EP (1) EP1858527A4 (ru)
JP (1) JP2008533135A (ru)
KR (1) KR20070120539A (ru)
AU (1) AU2006223757A1 (ru)
CA (1) CA2600399A1 (ru)
IL (1) IL185866A0 (ru)
NO (1) NO322682B1 (ru)
NZ (1) NZ561377A (ru)
RU (1) RU2007138582A (ru)
UA (1) UA90893C2 (ru)
WO (1) WO2006098628A1 (ru)
ZA (1) ZA200707979B (ru)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8497292B2 (en) 2005-12-28 2013-07-30 Translational Therapeutics, Inc. Translational dysfunction based therapeutics
WO2010039039A1 (en) * 2008-10-03 2010-04-08 Clavis Pharma Asa Oral formulations of gemcitabine derivatives
CN101525361B (zh) 2009-04-21 2010-11-17 济南圣鲁金药物技术开发有限公司 基于吉西他滨结构的前药及其合成方法及应用
GB0907551D0 (en) 2009-05-01 2009-06-10 Univ Dundee Treatment or prophylaxis of proliferative conditions
EP3494974B1 (en) 2011-07-08 2023-10-18 The University of North Carolina at Chapel Hill Metal bisphosphonate nanoparticles for anti-cancer therapy and imaging and for treating bone disorders
CN102432654A (zh) * 2011-09-26 2012-05-02 宋云龙 吉西他滨酰胺衍生物及其制备方法和用途
JP6420247B2 (ja) 2012-11-13 2018-11-07 ボーイエン セラピューティクス，インコーポレイティド ゲムシタビンプロドラッグ及びその使用
CN105873569B (zh) 2013-11-06 2020-07-28 芝加哥大学 用于化疗剂、核酸和光敏剂的递送或共递送的纳米级载体
US10463684B2 (en) 2014-01-29 2019-11-05 Board Of Regents, The Uneversety Of Texas System Nucleobase analogue derivatives and their applications
CN109310702A (zh) 2016-05-20 2019-02-05 芝加哥大学 用于化学疗法、靶向疗法、光动力疗法、免疫疗法和它们的任何组合的纳米颗粒
CN107184592A (zh) * 2017-05-17 2017-09-22 广东艾时代生物科技有限责任公司 吉西他滨在制备治疗类风湿性关节炎药物中的应用
WO2019028250A1 (en) 2017-08-02 2019-02-07 The University Of Chicago NOMOGENEOUS ORGANOMETALLIC ORGANOMETRIC ORGANOMETRIC LAYERS FOR X-RAY INDUCED PHOTODYNAMIC THERAPY, RADIOTHERAPY, RODIODYNAMIC THERAPY, CHEMOTHERAPY, IMMUNOTHERAPY, AND ANY COMBINATION THEREOF
KR20200118827A (ko) 2018-02-02 2020-10-16 마베릭스 온콜로지, 잉크. 젬시타빈 모노포스페이트의 소분자 약물 컨쥬게이트

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1327358C (en) * 1987-11-17 1994-03-01 Morio Fujiu Fluoro cytidine derivatives
KR100483256B1 (ko) * 1997-01-24 2005-04-15 콘파마 아에스 젬시타빈 유도체
WO2004041203A2 (en) * 2002-11-04 2004-05-21 Xenoport, Inc. Gemcitabine prodrugs, pharmaceutical compositions and uses thereof

Also Published As

Publication number Publication date
NZ561377A (en) 2009-10-30
NO20051467D0 (no) 2005-03-18
RU2007138582A (ru) 2009-04-27
WO2006098628A1 (en) 2006-09-21
EP1858527A4 (en) 2010-10-27
CA2600399A1 (en) 2006-09-21
US20080280851A1 (en) 2008-11-13
JP2008533135A (ja) 2008-08-21
AU2006223757A1 (en) 2006-09-21
KR20070120539A (ko) 2007-12-24
EP1858527A1 (en) 2007-11-28
IL185866A0 (en) 2008-01-06
ZA200707979B (en) 2008-11-26
NO322682B1 (no) 2006-11-27

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