ATE283038T1 - Verfahren zu herstellung einer granulären zubereitung - Google Patents

Verfahren zu herstellung einer granulären zubereitung

Info

Publication number
ATE283038T1
ATE283038T1 AT96924165T AT96924165T ATE283038T1 AT E283038 T1 ATE283038 T1 AT E283038T1 AT 96924165 T AT96924165 T AT 96924165T AT 96924165 T AT96924165 T AT 96924165T AT E283038 T1 ATE283038 T1 AT E283038T1
Authority
AT
Austria
Prior art keywords
powdered
granular preparation
medicine
producing
preparation
Prior art date
Application number
AT96924165T
Other languages
English (en)
Inventor
Hiroaki Nakagami
Tadanao Yamao
Ario Funada
Original Assignee
Daiichi Seiyaku Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Daiichi Seiyaku Co filed Critical Daiichi Seiyaku Co
Application granted granted Critical
Publication of ATE283038T1 publication Critical patent/ATE283038T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/501—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
    • A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
    • A61K9/5047—Cellulose ethers containing no ester groups, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1611—Inorganic compounds

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Saccharide Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
AT96924165T 1995-07-21 1996-07-19 Verfahren zu herstellung einer granulären zubereitung ATE283038T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP20672695 1995-07-21
PCT/JP1996/002028 WO1997003656A1 (fr) 1995-07-21 1996-07-19 Preparation granulaire et son procede de production

Publications (1)

Publication Number Publication Date
ATE283038T1 true ATE283038T1 (de) 2004-12-15

Family

ID=16528097

Family Applications (1)

Application Number Title Priority Date Filing Date
AT96924165T ATE283038T1 (de) 1995-07-21 1996-07-19 Verfahren zu herstellung einer granulären zubereitung

Country Status (13)

Country Link
US (1) US6217910B1 (de)
EP (1) EP0841062B1 (de)
KR (1) KR100417746B1 (de)
CN (1) CN1089235C (de)
AT (1) ATE283038T1 (de)
AU (1) AU700961B2 (de)
DE (1) DE69633925T2 (de)
EA (1) EA000467B1 (de)
ES (1) ES2233971T3 (de)
NO (1) NO324286B1 (de)
PT (1) PT841062E (de)
TW (1) TW503114B (de)
WO (1) WO1997003656A1 (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6242019B1 (en) 1997-08-14 2001-06-05 Warner-Lambert Company Taste modified hard confectionery compositions containing functional ingredients
HK1040191A1 (zh) * 1998-07-31 2002-05-31 大塚制药株式会社 具有改良味道的药物组合物
CA2367373C (en) * 1999-03-17 2011-09-20 Daiichi Pharmaceutical Co., Ltd. Medicinal compositions
JP4310605B2 (ja) 2001-05-25 2009-08-12 大塚製薬株式会社 医薬用組成物
JP4974419B2 (ja) * 2001-06-12 2012-07-11 東和薬品株式会社 薬物含有徐放性顆粒およびそれを含む錠剤
SE0200154D0 (sv) 2002-01-21 2002-01-21 Galenica Ab New process
CA2475441C (en) 2002-02-21 2011-07-05 Otsuka Pharmaceutical Co., Ltd. Sustained release preparations and process for producing the same
WO2005000312A1 (ja) 2003-06-27 2005-01-06 Otsuka Pharmaceutical Co., Ltd. 薬物徐放性粒子及びその製法
GB0322848D0 (en) * 2003-09-30 2003-10-29 Alpharma Ltd Tetracycline controlled release pharmaceutical dosage form
JP3981134B2 (ja) * 2003-10-29 2007-09-26 塩野義製薬株式会社 不快味を改善した被覆製剤の製造方法
US20060241144A1 (en) * 2005-04-20 2006-10-26 Albert Cha Method for treating apathy syndrome
PT2001445E (pt) 2006-03-16 2014-10-24 Euro Celtique Sa Esferoides farmacêuticos
JP2009073774A (ja) * 2007-09-21 2009-04-09 Takada Seiyaku Kk レボフロキサシン粒状製剤の製造方法及び該方法で得られた粒状製剤
EP2198859A1 (de) 2008-12-17 2010-06-23 Losan Pharma GmbH Schmelzbeschichtete pharmazeutische Zusammensetzung mit Freisetzung
US20220370368A1 (en) 2019-10-31 2022-11-24 Hermes Pharma Gmbh Oral pharmaceutical composition comprising a melt-agglomerated active ingredient core

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS58214333A (ja) 1982-06-04 1983-12-13 Dai Ichi Seiyaku Co Ltd 粒状物
IT1200217B (it) * 1986-09-30 1989-01-05 Valducci Roberto Membrana per uso farmaceutico ed industriale
US5169645A (en) 1989-10-31 1992-12-08 Duquesne University Of The Holy Ghost Directly compressible granules having improved flow properties
JP3130058B2 (ja) * 1991-02-15 2001-01-31 第一製薬株式会社 マスクされた粒状物
KR950703935A (ko) * 1992-11-30 1995-11-17 밋첼 아이, 커시너 맛을 차단하는 약제학적 조성물
IL116674A (en) * 1995-01-09 2003-05-29 Mendell Co Inc Edward Microcrystalline cellulose-based excipient having improved compressibility, pharmaceutical compositions containing the same and methods for the preparation of said excipient and of solid dosage form thereof

Also Published As

Publication number Publication date
ES2233971T3 (es) 2005-06-16
CN1089235C (zh) 2002-08-21
US6217910B1 (en) 2001-04-17
EA199800145A1 (ru) 1998-08-27
EP0841062A4 (de) 2000-07-19
WO1997003656A1 (fr) 1997-02-06
KR100417746B1 (ko) 2004-05-31
KR19990035794A (ko) 1999-05-25
NO980245D0 (no) 1998-01-20
TW503114B (en) 2002-09-21
AU700961B2 (en) 1999-01-14
CN1207674A (zh) 1999-02-10
DE69633925T2 (de) 2005-11-24
PT841062E (pt) 2005-03-31
AU6470796A (en) 1997-02-18
EA000467B1 (ru) 1999-08-26
EP0841062A1 (de) 1998-05-13
NO324286B1 (no) 2007-09-17
DE69633925D1 (de) 2004-12-30
NO980245L (no) 1998-03-23
EP0841062B1 (de) 2004-11-24
HK1008491A1 (en) 1999-07-16

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