ATE283038T1 - Verfahren zu herstellung einer granulären zubereitung - Google Patents
Verfahren zu herstellung einer granulären zubereitungInfo
- Publication number
- ATE283038T1 ATE283038T1 AT96924165T AT96924165T ATE283038T1 AT E283038 T1 ATE283038 T1 AT E283038T1 AT 96924165 T AT96924165 T AT 96924165T AT 96924165 T AT96924165 T AT 96924165T AT E283038 T1 ATE283038 T1 AT E283038T1
- Authority
- AT
- Austria
- Prior art keywords
- powdered
- granular preparation
- medicine
- producing
- preparation
- Prior art date
Links
- 238000002360 preparation method Methods 0.000 title abstract 3
- 238000004519 manufacturing process Methods 0.000 title 1
- 239000003814 drug Substances 0.000 abstract 2
- 239000002245 particle Substances 0.000 abstract 2
- 235000019596 Masking bitterness Nutrition 0.000 abstract 1
- 239000011248 coating agent Substances 0.000 abstract 1
- 238000000576 coating method Methods 0.000 abstract 1
- 239000003085 diluting agent Substances 0.000 abstract 1
- 230000002209 hydrophobic effect Effects 0.000 abstract 1
- 238000007909 melt granulation Methods 0.000 abstract 1
- 238000002844 melting Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 229920000642 polymer Polymers 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1617—Organic compounds, e.g. phospholipids, fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/501—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
- A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
- A61K9/5047—Cellulose ethers containing no ester groups, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1611—Inorganic compounds
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Inorganic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Medicines Containing Plant Substances (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP20672695 | 1995-07-21 | ||
| PCT/JP1996/002028 WO1997003656A1 (fr) | 1995-07-21 | 1996-07-19 | Preparation granulaire et son procede de production |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE283038T1 true ATE283038T1 (de) | 2004-12-15 |
Family
ID=16528097
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT96924165T ATE283038T1 (de) | 1995-07-21 | 1996-07-19 | Verfahren zu herstellung einer granulären zubereitung |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US6217910B1 (de) |
| EP (1) | EP0841062B1 (de) |
| KR (1) | KR100417746B1 (de) |
| CN (1) | CN1089235C (de) |
| AT (1) | ATE283038T1 (de) |
| AU (1) | AU700961B2 (de) |
| DE (1) | DE69633925T2 (de) |
| EA (1) | EA000467B1 (de) |
| ES (1) | ES2233971T3 (de) |
| NO (1) | NO324286B1 (de) |
| PT (1) | PT841062E (de) |
| TW (1) | TW503114B (de) |
| WO (1) | WO1997003656A1 (de) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6242019B1 (en) | 1997-08-14 | 2001-06-05 | Warner-Lambert Company | Taste modified hard confectionery compositions containing functional ingredients |
| CN1161106C (zh) * | 1998-07-31 | 2004-08-11 | 大塚制药株式会社 | 具有改良味道的药物组合物 |
| EP2275141A1 (de) * | 1999-03-17 | 2011-01-19 | Daiichi Pharmaceutical Co., Ltd. | Geschmacksmaskierte pharmazeutische Zusammensetzungen |
| JP4310605B2 (ja) | 2001-05-25 | 2009-08-12 | 大塚製薬株式会社 | 医薬用組成物 |
| JP4974419B2 (ja) * | 2001-06-12 | 2012-07-11 | 東和薬品株式会社 | 薬物含有徐放性顆粒およびそれを含む錠剤 |
| SE0200154D0 (sv) * | 2002-01-21 | 2002-01-21 | Galenica Ab | New process |
| MXPA04008137A (es) | 2002-02-21 | 2004-11-26 | Otsuka Pharma Co Ltd | Preparaciones de liberacion sostenida y procedimiento para producir las mismas. |
| CN1812793A (zh) * | 2003-06-27 | 2006-08-02 | 大塚制药株式会社 | 药物持续释放颗粒及其制备方法 |
| GB0322848D0 (en) * | 2003-09-30 | 2003-10-29 | Alpharma Ltd | Tetracycline controlled release pharmaceutical dosage form |
| KR101168189B1 (ko) * | 2003-10-29 | 2012-07-25 | 시오노기세이야쿠가부시키가이샤 | 불쾌미를 개선한 피복 제제의 제조 방법 |
| US20060241144A1 (en) * | 2005-04-20 | 2006-10-26 | Albert Cha | Method for treating apathy syndrome |
| DK2001445T3 (da) | 2006-03-16 | 2014-10-27 | Euro Celtique | Farmaceutiske sfæroider |
| JP2009073774A (ja) * | 2007-09-21 | 2009-04-09 | Takada Seiyaku Kk | レボフロキサシン粒状製剤の製造方法及び該方法で得られた粒状製剤 |
| EP2198859A1 (de) | 2008-12-17 | 2010-06-23 | Losan Pharma GmbH | Schmelzbeschichtete pharmazeutische Zusammensetzung mit Freisetzung |
| US20220370368A1 (en) | 2019-10-31 | 2022-11-24 | Hermes Pharma Gmbh | Oral pharmaceutical composition comprising a melt-agglomerated active ingredient core |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS58214333A (ja) | 1982-06-04 | 1983-12-13 | Dai Ichi Seiyaku Co Ltd | 粒状物 |
| IT1200217B (it) * | 1986-09-30 | 1989-01-05 | Valducci Roberto | Membrana per uso farmaceutico ed industriale |
| US5169645A (en) * | 1989-10-31 | 1992-12-08 | Duquesne University Of The Holy Ghost | Directly compressible granules having improved flow properties |
| JP3130058B2 (ja) * | 1991-02-15 | 2001-01-31 | 第一製薬株式会社 | マスクされた粒状物 |
| JP2949448B2 (ja) * | 1992-11-30 | 1999-09-13 | ケーヴィ ファーマセチカル カンパニー | 味を隠された医薬材料 |
| IL116674A (en) * | 1995-01-09 | 2003-05-29 | Mendell Co Inc Edward | Microcrystalline cellulose-based excipient having improved compressibility, pharmaceutical compositions containing the same and methods for the preparation of said excipient and of solid dosage form thereof |
-
1996
- 1996-07-19 ES ES96924165T patent/ES2233971T3/es not_active Expired - Lifetime
- 1996-07-19 DE DE69633925T patent/DE69633925T2/de not_active Expired - Lifetime
- 1996-07-19 AT AT96924165T patent/ATE283038T1/de not_active IP Right Cessation
- 1996-07-19 KR KR10-1998-0700453A patent/KR100417746B1/ko not_active Expired - Fee Related
- 1996-07-19 CN CN96196993A patent/CN1089235C/zh not_active Expired - Fee Related
- 1996-07-19 PT PT96924165T patent/PT841062E/pt unknown
- 1996-07-19 US US09/000,346 patent/US6217910B1/en not_active Expired - Lifetime
- 1996-07-19 EP EP96924165A patent/EP0841062B1/de not_active Expired - Lifetime
- 1996-07-19 WO PCT/JP1996/002028 patent/WO1997003656A1/ja not_active Ceased
- 1996-07-19 EA EA199800145A patent/EA000467B1/ru not_active IP Right Cessation
- 1996-07-19 AU AU64707/96A patent/AU700961B2/en not_active Ceased
- 1996-07-20 TW TW085108846A patent/TW503114B/zh not_active IP Right Cessation
-
1998
- 1998-01-20 NO NO19980245A patent/NO324286B1/no not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| PT841062E (pt) | 2005-03-31 |
| CN1207674A (zh) | 1999-02-10 |
| KR19990035794A (ko) | 1999-05-25 |
| EP0841062A1 (de) | 1998-05-13 |
| EP0841062A4 (de) | 2000-07-19 |
| TW503114B (en) | 2002-09-21 |
| NO324286B1 (no) | 2007-09-17 |
| EA199800145A1 (ru) | 1998-08-27 |
| CN1089235C (zh) | 2002-08-21 |
| NO980245D0 (no) | 1998-01-20 |
| HK1008491A1 (en) | 1999-07-16 |
| EA000467B1 (ru) | 1999-08-26 |
| DE69633925T2 (de) | 2005-11-24 |
| NO980245L (no) | 1998-03-23 |
| US6217910B1 (en) | 2001-04-17 |
| AU6470796A (en) | 1997-02-18 |
| ES2233971T3 (es) | 2005-06-16 |
| AU700961B2 (en) | 1999-01-14 |
| WO1997003656A1 (fr) | 1997-02-06 |
| DE69633925D1 (de) | 2004-12-30 |
| KR100417746B1 (ko) | 2004-05-31 |
| EP0841062B1 (de) | 2004-11-24 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
Ref document number: 0841062 Country of ref document: EP |
|
| REN | Ceased due to non-payment of the annual fee |