ATE283110T1 - Verfahren zur herstellung von teilchen - Google Patents
Verfahren zur herstellung von teilchenInfo
- Publication number
- ATE283110T1 ATE283110T1 AT99937888T AT99937888T ATE283110T1 AT E283110 T1 ATE283110 T1 AT E283110T1 AT 99937888 T AT99937888 T AT 99937888T AT 99937888 T AT99937888 T AT 99937888T AT E283110 T1 ATE283110 T1 AT E283110T1
- Authority
- AT
- Austria
- Prior art keywords
- fluid
- suspension
- solution
- substance
- inlet means
- Prior art date
Links
- 239000002245 particle Substances 0.000 title abstract 7
- 238000004519 manufacturing process Methods 0.000 title 1
- 239000012530 fluid Substances 0.000 abstract 12
- 230000015572 biosynthetic process Effects 0.000 abstract 5
- 239000000725 suspension Substances 0.000 abstract 5
- 239000000126 substance Substances 0.000 abstract 4
- 238000000034 method Methods 0.000 abstract 2
- 239000012296 anti-solvent Substances 0.000 abstract 1
- 230000000903 blocking effect Effects 0.000 abstract 1
- 238000011144 upstream manufacturing Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/16—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
- C07C233/24—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring
- C07C233/25—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring having the carbon atom of the carboxamide group bound to a hydrogen atom or to a carbon atom of an acyclic saturated carbon skeleton
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1682—Processes
- A61K9/1688—Processes resulting in pure drug agglomerate optionally containing up to 5% of excipient
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D11/00—Solvent extraction
- B01D11/04—Solvent extraction of solutions which are liquid
- B01D11/0403—Solvent extraction of solutions which are liquid with a supercritical fluid
- B01D11/0411—Solvent extraction of solutions which are liquid with a supercritical fluid the supercritical fluid acting as solvent for the solvent and as anti-solvent for the solute, e.g. formation of particles from solutions
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2/00—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic
- B01J2/02—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic by dividing the liquid material into drops, e.g. by spraying, and solidifying the drops
- B01J2/04—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic by dividing the liquid material into drops, e.g. by spraying, and solidifying the drops in a gaseous medium
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/54—Improvements relating to the production of bulk chemicals using solvents, e.g. supercritical solvents or ionic liquids
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Physical Or Chemical Processes And Apparatus (AREA)
- Medicinal Preparation (AREA)
- Glanulating (AREA)
- Devices And Processes Conducted In The Presence Of Fluids And Solid Particles (AREA)
- Extraction Or Liquid Replacement (AREA)
- Manufacturing Of Micro-Capsules (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9804379.7A GB9804379D0 (en) | 1998-03-02 | 1998-03-02 | Method of particle formation |
| PCT/GB1999/000587 WO1999044733A1 (en) | 1998-03-02 | 1999-02-26 | Method of particle formation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE283110T1 true ATE283110T1 (de) | 2004-12-15 |
Family
ID=10827831
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT99937888T ATE283110T1 (de) | 1998-03-02 | 1999-02-26 | Verfahren zur herstellung von teilchen |
Country Status (11)
| Country | Link |
|---|---|
| EP (1) | EP1060008B1 (de) |
| JP (1) | JP4593777B2 (de) |
| AT (1) | ATE283110T1 (de) |
| AU (1) | AU753115B2 (de) |
| CA (1) | CA2321741C (de) |
| DE (1) | DE69922173T2 (de) |
| ES (1) | ES2232158T3 (de) |
| GB (2) | GB9804379D0 (de) |
| MX (1) | MXPA00008428A (de) |
| WO (1) | WO1999044733A1 (de) |
| ZA (1) | ZA991667B (de) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HK1049621A1 (zh) | 1999-06-09 | 2003-05-23 | 罗伯特‧E‧希弗斯 | 超临界流体辅助的喷雾和鼓泡乾燥 |
| GB9915975D0 (en) * | 1999-07-07 | 1999-09-08 | Bradford Particle Design Ltd | Method for the formation of particles |
| GB0027357D0 (en) | 2000-11-09 | 2000-12-27 | Bradford Particle Design Plc | Particle formation methods and their products |
| AU2002221320B2 (en) * | 2000-12-08 | 2006-06-15 | The University Of Sydney | Synthesis of small particles |
| AUPR197000A0 (en) | 2000-12-08 | 2001-01-11 | Unisearch Limited | Synthesis of small particles |
| GB0102075D0 (en) | 2001-01-26 | 2001-03-14 | Astrazeneca Ab | Process |
| EP1414633A4 (de) * | 2001-07-10 | 2005-01-26 | Univ Technology Corp | Vorrichtung und verfahren zur herstellung von teilchen |
| GB0208742D0 (en) | 2002-04-17 | 2002-05-29 | Bradford Particle Design Ltd | Particulate materials |
| GB0126716D0 (en) * | 2001-11-07 | 2002-01-02 | Advanced Phytonics Ltd | Method for the production of particles |
| US7582284B2 (en) | 2002-04-17 | 2009-09-01 | Nektar Therapeutics | Particulate materials |
| WO2004098561A2 (en) | 2003-05-08 | 2004-11-18 | Nektar Therapeutics Uk Ltd | Particulate materials |
| AU2006272438B2 (en) | 2005-07-15 | 2011-08-04 | Map Pharmaceuticals, Inc. | Method of particle formation |
| US7744923B2 (en) | 2006-10-11 | 2010-06-29 | Crititech, Inc. | Method for precipitation of small medicament particles into use containers |
| WO2008097664A1 (en) | 2007-02-11 | 2008-08-14 | Map Pharmaceuticals, Inc. | Method of therapeutic administration of dhe to enable rapid relief of migraine while minimizing side effect profile |
| US8585943B2 (en) | 2007-12-07 | 2013-11-19 | Xspray Microparticles Ab | Method and arrangement for the production of particles |
| US8323685B2 (en) | 2008-08-20 | 2012-12-04 | Baxter International Inc. | Methods of processing compositions containing microparticles |
| US8323615B2 (en) * | 2008-08-20 | 2012-12-04 | Baxter International Inc. | Methods of processing multi-phasic dispersions |
| US8367427B2 (en) | 2008-08-20 | 2013-02-05 | Baxter International Inc. | Methods of processing compositions containing microparticles |
| MX350838B (es) | 2011-02-11 | 2017-09-18 | Grain Proc Corporation * | Composicion de sal. |
| GB201402556D0 (en) | 2014-02-13 | 2014-04-02 | Crystec Ltd | Improvements relating to inhalable particles |
| CA2986349A1 (en) | 2015-07-22 | 2017-01-26 | Anavex Life Sciences Corp. | Crystal forms of tetrahydro-n,n-dimethyl-2,2-diphenyl-3-furanmethanamine hydrochloride, processes of making such forms, and their pharmaceutical compositions |
| CN111530103B (zh) * | 2020-05-08 | 2021-08-31 | 福建蓝烟新材料有限公司 | 一种超临界喷雾干燥方法 |
| GB202312252D0 (en) | 2023-08-10 | 2023-09-27 | Inhalis Therapeutics Sa | Crystalline compositions |
| GB202318661D0 (en) | 2023-12-06 | 2024-01-17 | Crystec Ltd | Tranexamic acid compositions |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9313642D0 (en) * | 1993-07-01 | 1993-08-18 | Glaxo Group Ltd | Method and apparatus for the formation of particles |
| SI9400079B (sl) * | 1994-02-15 | 2003-02-28 | Dr. Weidner Eckhard, Dipl. Ing. | Postopek in naprava za pridobivanje in frakcioniranje majhnih delcev iz raztopin nasičenih s plinom |
| GB9413202D0 (en) * | 1994-06-30 | 1994-08-24 | Univ Bradford | Method and apparatus for the formation of particles |
| WO1997031691A1 (en) * | 1996-03-01 | 1997-09-04 | The University Of Kansas | Methods and apparatus for particle precipitation and coating using near-critical and supercritical antisolvents |
| GB9703673D0 (en) * | 1997-02-21 | 1997-04-09 | Bradford Particle Design Ltd | Method and apparatus for the formation of particles |
| US6228394B1 (en) * | 1997-10-14 | 2001-05-08 | Boehringer Ingelheim Pharmaceuticals, Inc. | Supercritical fluid extraction of mould lubricant from hard shell capsules |
-
1998
- 1998-03-02 GB GBGB9804379.7A patent/GB9804379D0/en not_active Ceased
-
1999
- 1999-02-26 WO PCT/GB1999/000587 patent/WO1999044733A1/en not_active Ceased
- 1999-02-26 AU AU32601/99A patent/AU753115B2/en not_active Expired
- 1999-02-26 EP EP99937888A patent/EP1060008B1/de not_active Expired - Lifetime
- 1999-02-26 MX MXPA00008428A patent/MXPA00008428A/es active IP Right Grant
- 1999-02-26 AT AT99937888T patent/ATE283110T1/de not_active IP Right Cessation
- 1999-02-26 CA CA002321741A patent/CA2321741C/en not_active Expired - Lifetime
- 1999-02-26 DE DE69922173T patent/DE69922173T2/de not_active Expired - Lifetime
- 1999-02-26 JP JP2000534325A patent/JP4593777B2/ja not_active Expired - Fee Related
- 1999-02-26 ES ES99937888T patent/ES2232158T3/es not_active Expired - Lifetime
- 1999-03-01 GB GB9904658A patent/GB2334900B/en not_active Expired - Lifetime
- 1999-03-02 ZA ZA9901667A patent/ZA991667B/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP1060008A1 (de) | 2000-12-20 |
| GB9804379D0 (en) | 1998-04-22 |
| EP1060008B1 (de) | 2004-11-24 |
| JP2002505182A (ja) | 2002-02-19 |
| CA2321741A1 (en) | 1999-09-10 |
| DE69922173D1 (de) | 2004-12-30 |
| GB2334900B (en) | 2000-04-19 |
| ZA991667B (en) | 1999-11-16 |
| CA2321741C (en) | 2007-10-30 |
| MXPA00008428A (es) | 2003-04-25 |
| AU3260199A (en) | 1999-09-20 |
| GB2334900A (en) | 1999-09-08 |
| JP4593777B2 (ja) | 2010-12-08 |
| DE69922173T2 (de) | 2005-12-01 |
| GB9904658D0 (en) | 1999-04-21 |
| WO1999044733A1 (en) | 1999-09-10 |
| AU753115B2 (en) | 2002-10-10 |
| ES2232158T3 (es) | 2005-05-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |