ATE283355T1 - Mimetika von aus alternden zellen abgeleitete hemmer der dna synthese - Google Patents
Mimetika von aus alternden zellen abgeleitete hemmer der dna syntheseInfo
- Publication number
- ATE283355T1 ATE283355T1 AT95921340T AT95921340T ATE283355T1 AT E283355 T1 ATE283355 T1 AT E283355T1 AT 95921340 T AT95921340 T AT 95921340T AT 95921340 T AT95921340 T AT 95921340T AT E283355 T1 ATE283355 T1 AT E283355T1
- Authority
- AT
- Austria
- Prior art keywords
- mimetics
- inhibiters
- dna synthesis
- aging cells
- synthesis derived
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
- A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
- A61K9/1272—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers comprising non-phosphatidyl surfactants as bilayer-forming substances, e.g. cationic lipids or non-phosphatidyl liposomes coated or grafted with polymers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4702—Regulators; Modulating activity
- C07K14/4703—Inhibitors; Suppressors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
- C12N2310/11—Antisense
- C12N2310/111—Antisense spanning the whole gene, or a large part of it
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/30—Chemical structure
- C12N2310/32—Chemical structure of the sugar
- C12N2310/322—2'-R Modification
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Molecular Biology (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- Biophysics (AREA)
- Biomedical Technology (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Wood Science & Technology (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- General Engineering & Computer Science (AREA)
- Gastroenterology & Hepatology (AREA)
- Physics & Mathematics (AREA)
- Immunology (AREA)
- Plant Pathology (AREA)
- Dispersion Chemistry (AREA)
- Microbiology (AREA)
- Toxicology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/249,371 US5596079A (en) | 1991-12-16 | 1994-05-24 | Mimetics of senescent cell derived inhibitors of DNA synthesis |
| US26843994A | 1994-06-30 | 1994-06-30 | |
| US27453594A | 1994-07-13 | 1994-07-13 | |
| PCT/US1994/009700 WO1995006415A1 (en) | 1993-08-30 | 1994-08-26 | Senescent cell-derived inhibitors of dna synthesis |
| US32181494A | 1994-10-03 | 1994-10-03 | |
| US08/327,874 US6372249B1 (en) | 1991-12-16 | 1994-10-24 | Senscent cell-derived inhibitors of DNA synthesis |
| PCT/US1995/006451 WO1995031995A1 (en) | 1994-05-24 | 1995-05-23 | Mimetics of senescent cell derived inhibitors of dna synthesis |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE283355T1 true ATE283355T1 (de) | 2004-12-15 |
Family
ID=27557474
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT95921340T ATE283355T1 (de) | 1994-05-24 | 1995-05-23 | Mimetika von aus alternden zellen abgeleitete hemmer der dna synthese |
Country Status (6)
| Country | Link |
|---|---|
| EP (1) | EP0783317B1 (de) |
| AT (1) | ATE283355T1 (de) |
| AU (1) | AU2644495A (de) |
| DE (1) | DE69533804T2 (de) |
| ES (1) | ES2233943T3 (de) |
| WO (1) | WO1995031995A1 (de) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9422175D0 (en) | 1994-11-03 | 1994-12-21 | Univ Dundee | Indentification of the p21 waf1-pcna interaction site and therapeutic applications thereof |
| WO1997042222A1 (en) | 1996-05-08 | 1997-11-13 | Cyclacel Limited | Methods and means for inhibition of cdk4 activity |
| CA2546287C (en) | 2003-11-24 | 2014-04-22 | Canji, Inc. | Reduction of dermal scarring |
| ES2403558T3 (es) | 2004-08-27 | 2013-05-20 | Cyclacel Limited | Inhibidores purínicos y pirimidínicos de CDK y su uso para el tratamiento de enfermedades autoinmunitarias |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5302706A (en) * | 1991-12-16 | 1994-04-12 | Baylor College Of Medicine | Senescent cell derived inhibitors of DNA synthesis |
| CA2146965C (en) * | 1992-10-16 | 2003-07-29 | David H. Beach | Cyclin complex rearrangement and uses related thereto |
| CA2170641C (en) * | 1993-08-30 | 2011-11-15 | James R. Smith | Senescent cell-derived inhibitors of dna synthesis |
| AU695540B2 (en) * | 1993-10-27 | 1998-08-13 | Trustees Of Columbia University In The City Of New York, The | Method for generating a subtracted cDNA library and uses of the generated library |
| WO1995013375A1 (en) * | 1993-11-10 | 1995-05-18 | The Johns Hopkins University | Tumor suppressor waf1 |
| GB9422175D0 (en) * | 1994-11-03 | 1994-12-21 | Univ Dundee | Indentification of the p21 waf1-pcna interaction site and therapeutic applications thereof |
-
1995
- 1995-05-23 DE DE69533804T patent/DE69533804T2/de not_active Expired - Lifetime
- 1995-05-23 AT AT95921340T patent/ATE283355T1/de not_active IP Right Cessation
- 1995-05-23 ES ES95921340T patent/ES2233943T3/es not_active Expired - Lifetime
- 1995-05-23 WO PCT/US1995/006451 patent/WO1995031995A1/en not_active Ceased
- 1995-05-23 EP EP95921340A patent/EP0783317B1/de not_active Expired - Lifetime
- 1995-05-23 AU AU26444/95A patent/AU2644495A/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| DE69533804D1 (de) | 2004-12-30 |
| DE69533804T2 (de) | 2006-05-11 |
| EP0783317A1 (de) | 1997-07-16 |
| AU2644495A (en) | 1995-12-18 |
| WO1995031995A1 (en) | 1995-11-30 |
| ES2233943T3 (es) | 2005-06-16 |
| EP0783317B1 (de) | 2004-11-24 |
| EP0783317A4 (de) | 1997-12-10 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |