ATE284405T1 - Neues verfahren zur herstellung von oxabispidinen - Google Patents

Neues verfahren zur herstellung von oxabispidinen

Info

Publication number: ATE284405T1
Authority: AT; Austria
Prior art keywords: sup; formula; compound; oxabispidines; producing
Prior art date: 2001-04-12

Application number

AT02718766T

Other languages

English (en)

Inventor

Lal Cheema

David Cladingboel

Rhona Sinclair

Original Assignee

Astrazeneca Ab

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-04-12

Filing date

2002-04-12

Publication date

2004-12-15

2002-04-12 Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab

2004-12-15 Application granted granted Critical

2004-12-15 Publication of ATE284405T1 publication Critical patent/ATE284405T1/de

Links

238000000034 method Methods 0.000 title abstract 3
150000001875 compounds Chemical class 0.000 abstract 4
LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 2
238000006243 chemical reaction Methods 0.000 abstract 2
239000003795 chemical substances by application Substances 0.000 abstract 2
HRPVXLWXLXDGHG-UHFFFAOYSA-N Acrylamide Chemical compound NC(=O)C=C HRPVXLWXLXDGHG-UHFFFAOYSA-N 0.000 abstract 1
239000012948 isocyanate Substances 0.000 abstract 1
150000002513 isocyanates Chemical class 0.000 abstract 1
230000003647 oxidation Effects 0.000 abstract 1
238000007254 oxidation reaction Methods 0.000 abstract 1
230000008707 rearrangement Effects 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/08—Bridged systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Life Sciences & Earth Sciences (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Engineering & Computer Science (AREA)
Pharmacology & Pharmacy (AREA)
Bioinformatics & Cheminformatics (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Plural Heterocyclic Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Steroid Compounds (AREA)

AT02718766T 2001-04-12 2002-04-12 Neues verfahren zur herstellung von oxabispidinen ATE284405T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
SE0101324A SE0101324D0 (sv)	2001-04-12	2001-04-12	New process
PCT/SE2002/000727 WO2002083690A1 (en)	2001-04-12	2002-04-12	New process for the preparation of oxabispidines

Publications (1)

Publication Number	Publication Date
ATE284405T1 true ATE284405T1 (de)	2004-12-15

Family

ID=20283781

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT02718766T ATE284405T1 (de)	2001-04-12	2002-04-12	Neues verfahren zur herstellung von oxabispidinen

Country Status (19)

Country	Link
US (2)	US7169921B2 (de)
EP (1)	EP1385850B1 (de)
JP (1)	JP4248880B2 (de)
KR (1)	KR100848613B1 (de)
CN (1)	CN1267435C (de)
AT (1)	ATE284405T1 (de)
AU (1)	AU2002249748B2 (de)
BR (1)	BR0208861A (de)
CA (1)	CA2443475A1 (de)
DE (1)	DE60202203T2 (de)
ES (1)	ES2233809T3 (de)
IL (2)	IL158249A0 (de)
MX (1)	MXPA03009211A (de)
NO (1)	NO20034526L (de)
NZ (1)	NZ528515A (de)
PT (1)	PT1385850E (de)
SE (1)	SE0101324D0 (de)
WO (1)	WO2002083690A1 (de)
ZA (1)	ZA200307676B (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
SE0101324D0 (sv) *	2001-04-12	2001-04-12	Astrazeneca Ab	New process
GB0223712D0 (en)	2002-10-14	2002-11-20	Astrazeneca Ab	Chemical intermediate
US20040192738A1 (en) *	2003-03-18	2004-09-30	Aventis Pharma Deutschland Gmbh	2-(Butyl-1-sulfonylamino)-N-[1(R)-(6-methoxypyridin-3-yl)propyl] benzamide, its use as a medicament, and pharmaceutical preparations comprising it
SE0401539D0 (sv) *	2004-06-15	2004-06-15	Astrazeneca Ab	New compounds
SE0401540D0 (sv)	2004-06-15	2004-06-15	Astrazeneca Ab	New compounds
KR20080021114A (ko) *	2005-06-13	2008-03-06	아스트라제네카 아베	심부정맥의 치료를 위한 신규한 옥사비스피딘 화합물
WO2006134124A1 (en) *	2005-06-16	2006-12-21	Girindus Ag	Synthesis of hydroquinone derivatives
JP2008546765A (ja) *	2005-06-20	2008-12-25	アストラゼネカアクチボラグ	（アルコキシカルボニルアミノ）−アルキルスルホネートの製造方法
KR20080028435A (ko) *	2005-06-20	2008-03-31	아스트라제네카 아베	Ｎ,ｎ’-이치환된 옥사비스피딘의 제조 방법
AR054284A1 (es) *	2005-06-20	2007-06-13	Astrazeneca Ab	Procedimiento para la preparacion de sales de acido sulfonico de oxabispidinas
AR053901A1 (es) *	2005-06-20	2007-05-23	Astrazeneca Ab	Formas fisicas de oxabispidinas n,n'- disustituidas
AR057364A1 (es) *	2005-06-20	2007-11-28	Astrazeneca Ab	Proceso para el aislamiento de 4-(oxiranilmetoxi) -benzonitrilos
AU2006259936B2 (en) *	2005-06-20	2010-08-12	Astrazeneca Ab	Process for the preparation of 3,7-dihydroxy-1,5-diazacyclooctanes
JP6426694B2 (ja)	2013-03-15	2018-11-21	グローバルブラッドセラピューティクスインコーポレイテッド	ヘモグロビンの修飾のための化合物及びその使用
EA201992707A1 (ru)	2013-11-18	2020-06-30	Глобал Блад Терапьютикс, Инк.	Соединения и их применения для модуляции гемоглобина

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3196154A (en) *	1962-05-17	1965-07-20	Sterling Drug Inc	3-substituted-9-methyl-3, 9-diazabicyclo [3.3.1] nonanes
US5110933A (en) *	1989-11-13	1992-05-05	Board Of Regents Of Oklahoma State University	Salts of 3-azabicyclo[3.3.1]nonanes as antiarrhythmic agents, and precursors thereof
SE9704709D0 (sv) *	1997-12-17	1997-12-17	Astra Ab	Pharmaceutically active compounds
SE9903759D0 (sv) *	1999-10-18	1999-10-18	Astra Ab	Pharmaceutically active compounds
SE0101324D0 (sv) *	2001-04-12	2001-04-12	Astrazeneca Ab	New process

2001
- 2001-04-12 SE SE0101324A patent/SE0101324D0/xx unknown
2002
- 2002-04-12 IL IL15824902A patent/IL158249A0/xx unknown
- 2002-04-12 BR BR0208861-4A patent/BR0208861A/pt not_active IP Right Cessation
- 2002-04-12 CA CA002443475A patent/CA2443475A1/en not_active Abandoned
- 2002-04-12 JP JP2002581445A patent/JP4248880B2/ja not_active Expired - Fee Related
- 2002-04-12 CN CNB028115759A patent/CN1267435C/zh not_active Expired - Fee Related
- 2002-04-12 DE DE60202203T patent/DE60202203T2/de not_active Expired - Lifetime
- 2002-04-12 NZ NZ528515A patent/NZ528515A/en unknown
- 2002-04-12 PT PT02718766T patent/PT1385850E/pt unknown
- 2002-04-12 WO PCT/SE2002/000727 patent/WO2002083690A1/en not_active Ceased
- 2002-04-12 KR KR1020037013158A patent/KR100848613B1/ko not_active Expired - Fee Related
- 2002-04-12 EP EP02718766A patent/EP1385850B1/de not_active Expired - Lifetime
- 2002-04-12 AT AT02718766T patent/ATE284405T1/de not_active IP Right Cessation
- 2002-04-12 MX MXPA03009211A patent/MXPA03009211A/es active IP Right Grant
- 2002-04-12 ES ES02718766T patent/ES2233809T3/es not_active Expired - Lifetime
- 2002-04-12 US US10/474,593 patent/US7169921B2/en not_active Expired - Fee Related
- 2002-04-12 AU AU2002249748A patent/AU2002249748B2/en not_active Ceased
2003
- 2003-10-01 ZA ZA200307676A patent/ZA200307676B/en unknown
- 2003-10-02 IL IL158249A patent/IL158249A/en not_active IP Right Cessation
- 2003-10-09 NO NO20034526A patent/NO20034526L/no not_active Application Discontinuation
2006
- 2006-12-19 US US11/612,826 patent/US20070197519A1/en not_active Abandoned

Also Published As

Publication number	Publication date
BR0208861A (pt)	2004-10-19
JP4248880B2 (ja)	2009-04-02
KR20030087065A (ko)	2003-11-12
ZA200307676B (en)	2004-07-13
WO2002083690A1 (en)	2002-10-24
PT1385850E (pt)	2005-03-31
SE0101324D0 (sv)	2001-04-12
CN1520417A (zh)	2004-08-11
ES2233809T3 (es)	2005-06-16
US20070197519A1 (en)	2007-08-23
NZ528515A (en)	2005-06-24
NO20034526L (no)	2003-10-31
JP2004533432A (ja)	2004-11-04
US20040181060A1 (en)	2004-09-16
IL158249A0 (en)	2004-05-12
IL158249A (en)	2009-09-01
CA2443475A1 (en)	2002-10-24
KR100848613B1 (ko)	2008-07-28
US7169921B2 (en)	2007-01-30
NO20034526D0 (no)	2003-10-09
DE60202203T2 (de)	2005-12-15
HK1060886A1 (en)	2004-08-27
DE60202203D1 (de)	2005-01-13
MXPA03009211A (es)	2004-01-29
CN1267435C (zh)	2006-08-02
AU2002249748B2 (en)	2008-02-28
EP1385850B1 (de)	2004-12-08
EP1385850A1 (de)	2004-02-04

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Legal Events

Date

Code

Title

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2005-07-15

UEP

Publication of translation of european patent specification

Ref document number: 1385850

Country of ref document: EP

2012-01-15

REN

Ceased due to non-payment of the annual fee