ATE284678T1 - Acetaminophen mit verlängerter freisetzung - Google Patents
Acetaminophen mit verlängerter freisetzungInfo
- Publication number
- ATE284678T1 ATE284678T1 AT99948117T AT99948117T ATE284678T1 AT E284678 T1 ATE284678 T1 AT E284678T1 AT 99948117 T AT99948117 T AT 99948117T AT 99948117 T AT99948117 T AT 99948117T AT E284678 T1 ATE284678 T1 AT E284678T1
- Authority
- AT
- Austria
- Prior art keywords
- percent
- acetaminophen
- dissolution
- extended release
- acetaminophene
- Prior art date
Links
- RZVAJINKPMORJF-UHFFFAOYSA-N Acetaminophen Chemical compound CC(=O)NC1=CC=C(O)C=C1 RZVAJINKPMORJF-UHFFFAOYSA-N 0.000 title abstract 15
- 238000013265 extended release Methods 0.000 title abstract 4
- 229960005489 paracetamol Drugs 0.000 abstract 7
- 238000004090 dissolution Methods 0.000 abstract 5
- 239000000203 mixture Substances 0.000 abstract 3
- 239000007903 gelatin capsule Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000002245 particle Substances 0.000 abstract 1
- 239000008363 phosphate buffer Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5084—Mixtures of one or more drugs in different galenical forms, at least one of which being granules, microcapsules or (coated) microparticles according to A61K9/16 or A61K9/50, e.g. for obtaining a specific release pattern or for combining different drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
- A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
- A61K9/5047—Cellulose ethers containing no ester groups, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
- A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/146,248 US6126967A (en) | 1998-09-03 | 1998-09-03 | Extended release acetaminophen particles |
| PCT/US1999/020273 WO2000013678A1 (en) | 1998-09-03 | 1999-09-03 | Extended release acetaminophen |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE284678T1 true ATE284678T1 (de) | 2005-01-15 |
Family
ID=22516495
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT99948117T ATE284678T1 (de) | 1998-09-03 | 1999-09-03 | Acetaminophen mit verlängerter freisetzung |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US6126967A (de) |
| EP (1) | EP1109540B1 (de) |
| AT (1) | ATE284678T1 (de) |
| AU (2) | AU5802299A (de) |
| CA (1) | CA2339931C (de) |
| DE (1) | DE69922664T2 (de) |
| ES (1) | ES2234301T3 (de) |
| WO (2) | WO2000013673A1 (de) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7964192B1 (en) * | 1997-12-02 | 2011-06-21 | Janssen Alzheimer Immunotherapy | Prevention and treatment of amyloidgenic disease |
| WO2001019901A2 (en) * | 1999-09-14 | 2001-03-22 | Smithkline Beecham Corporation | Process for making aqueous coated beadlets |
| GB0009522D0 (en) * | 2000-04-19 | 2000-06-07 | Smithkline Beecham Plc | Composition |
| US7101573B2 (en) | 2001-09-28 | 2006-09-05 | Mcneil-Pcc, Inc. | Simethicone solid oral dosage form |
| US8110223B2 (en) * | 2002-12-31 | 2012-02-07 | University Of Maryland, Baltimore | Methods for making pharmaceutical dosage forms containing active cushioning components |
| US20040186180A1 (en) | 2003-03-21 | 2004-09-23 | Gelotte Cathy K. | Non-steroidal anti-inflammatory drug dosing regimen |
| US20050095300A1 (en) * | 2003-10-30 | 2005-05-05 | Wynn David W. | Controlled release analgesic suspensions |
| US20050095299A1 (en) * | 2003-10-30 | 2005-05-05 | Wynn David W. | Controlled release analgesic suspensions |
| US20080069891A1 (en) | 2006-09-15 | 2008-03-20 | Cima Labs, Inc. | Abuse resistant drug formulation |
| US9226907B2 (en) | 2008-02-01 | 2016-01-05 | Abbvie Inc. | Extended release hydrocodone acetaminophen and related methods and uses thereof |
| US20090264530A1 (en) * | 2008-04-16 | 2009-10-22 | Nickell Robert P | Combined nsaid and acetaminophen formulation and method |
| KR101573889B1 (ko) | 2009-10-09 | 2015-12-04 | 영진약품공업주식회사 | 속효성과 지속성을 동시에 갖는 약제학적 조성물 |
| HRP20220112T1 (hr) | 2013-12-24 | 2022-04-15 | Virginia Commonwealth University | Upotreba oksidacijskog sulfata kolesterola (ocs) za liječenje akutne insuficijencije jetre |
| EP3344240A4 (de) * | 2015-09-01 | 2019-09-04 | Wellesley Pharmaceuticals, LLC | Formulierung mit erweiterter, verzögerter und sofortiger freisetzung, verfahren zur herstellung und verwendung davon |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IE58110B1 (en) * | 1984-10-30 | 1993-07-14 | Elan Corp Plc | Controlled release powder and process for its preparation |
| US4867984A (en) * | 1984-11-06 | 1989-09-19 | Nagin K. Patel | Drug in bead form and process for preparing same |
| US4874613A (en) * | 1987-03-06 | 1989-10-17 | Baker Cummins Pharmaceuticals, Inc. | Taste concealing pharmaceutical dosage unit |
| US4820522A (en) * | 1987-07-27 | 1989-04-11 | Mcneilab, Inc. | Oral sustained release acetaminophen formulation and process |
| US5032384A (en) * | 1989-01-27 | 1991-07-16 | Block Drug Company, Inc. | Compositions and method for the treatment of disease |
| US5026559A (en) * | 1989-04-03 | 1991-06-25 | Kinaform Technology, Inc. | Sustained-release pharmaceutical preparation |
| US5133974A (en) * | 1989-05-05 | 1992-07-28 | Kv Pharmaceutical Company | Extended release pharmaceutical formulations |
| US4983401A (en) * | 1989-05-22 | 1991-01-08 | Kinaform Technology, Inc. | Sustained release pharmaceutical preparations having pH controlled membrane coatings |
| US5273760A (en) * | 1991-12-24 | 1993-12-28 | Euroceltigue, S.A. | Stabilized controlled release substrate having a coating derived from an aqueous dispersion of hydrophobic polymer |
| JPH0971524A (ja) * | 1995-09-08 | 1997-03-18 | Fujisawa Pharmaceut Co Ltd | 徐放性粒剤およびその製造方法 |
| US5773031A (en) * | 1996-02-27 | 1998-06-30 | L. Perrigo Company | Acetaminophen sustained-release formulation |
| US5780055A (en) * | 1996-09-06 | 1998-07-14 | University Of Maryland, Baltimore | Cushioning beads and tablet comprising the same capable of forming a suspension |
-
1998
- 1998-09-03 US US09/146,248 patent/US6126967A/en not_active Expired - Lifetime
-
1999
- 1999-09-01 WO PCT/US1999/020113 patent/WO2000013673A1/en not_active Ceased
- 1999-09-01 AU AU58022/99A patent/AU5802299A/en not_active Withdrawn
- 1999-09-03 AT AT99948117T patent/ATE284678T1/de not_active IP Right Cessation
- 1999-09-03 EP EP99948117A patent/EP1109540B1/de not_active Expired - Lifetime
- 1999-09-03 WO PCT/US1999/020273 patent/WO2000013678A1/en not_active Ceased
- 1999-09-03 ES ES99948117T patent/ES2234301T3/es not_active Expired - Lifetime
- 1999-09-03 AU AU61357/99A patent/AU751194B2/en not_active Ceased
- 1999-09-03 CA CA002339931A patent/CA2339931C/en not_active Expired - Fee Related
- 1999-09-03 DE DE69922664T patent/DE69922664T2/de not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| CA2339931C (en) | 2006-04-18 |
| HK1034900A1 (en) | 2001-11-09 |
| EP1109540A1 (de) | 2001-06-27 |
| EP1109540A4 (de) | 2002-03-20 |
| DE69922664T2 (de) | 2005-12-01 |
| WO2000013673A1 (en) | 2000-03-16 |
| AU6135799A (en) | 2000-03-27 |
| WO2000013678A9 (en) | 2001-02-01 |
| WO2000013673A8 (en) | 2000-08-24 |
| DE69922664D1 (de) | 2005-01-20 |
| AU751194B2 (en) | 2002-08-08 |
| WO2000013678A1 (en) | 2000-03-16 |
| US6126967A (en) | 2000-10-03 |
| EP1109540B1 (de) | 2004-12-15 |
| AU5802299A (en) | 2000-03-27 |
| CA2339931A1 (en) | 2000-03-16 |
| ES2234301T3 (es) | 2005-06-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |