ATE209495T1 - Antiatherosclerotische mittel - Google Patents

Antiatherosclerotische mittel

Info

Publication number
ATE209495T1
ATE209495T1 AT94906461T AT94906461T ATE209495T1 AT E209495 T1 ATE209495 T1 AT E209495T1 AT 94906461 T AT94906461 T AT 94906461T AT 94906461 T AT94906461 T AT 94906461T AT E209495 T1 ATE209495 T1 AT E209495T1
Authority
AT
Austria
Prior art keywords
ester
dihydroequilin
alpha
sulfate
absence
Prior art date
Application number
AT94906461T
Other languages
English (en)
Inventor
Steven Jay Adelman
Kurt Edric Steiner
Original Assignee
American Home Prod
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/157,661 external-priority patent/US5482935A/en
Application filed by American Home Prod filed Critical American Home Prod
Application granted granted Critical
Publication of ATE209495T1 publication Critical patent/ATE209495T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Steroid Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Medicinal Preparation (AREA)
AT94906461T 1993-01-05 1993-12-22 Antiatherosclerotische mittel ATE209495T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US77793A 1993-01-05 1993-01-05
US08/157,661 US5482935A (en) 1993-01-05 1993-12-01 Anti-atherosclerotic use of 17 alpha-dihydroequilin
PCT/US1993/012559 WO1994015612A1 (en) 1993-01-05 1993-12-22 Anti-atherosclerotic agents

Publications (1)

Publication Number Publication Date
ATE209495T1 true ATE209495T1 (de) 2001-12-15

Family

ID=26668138

Family Applications (1)

Application Number Title Priority Date Filing Date
AT94906461T ATE209495T1 (de) 1993-01-05 1993-12-22 Antiatherosclerotische mittel

Country Status (16)

Country Link
EP (1) EP0678027B1 (de)
JP (1) JP3344585B2 (de)
CN (1) CN1071573C (de)
AT (1) ATE209495T1 (de)
AU (1) AU6015794A (de)
CA (1) CA2152187A1 (de)
CY (1) CY2361B1 (de)
DE (1) DE69331237T2 (de)
DK (1) DK0678027T3 (de)
ES (1) ES2165382T3 (de)
IL (1) IL108155A (de)
MX (1) MX9400254A (de)
PH (1) PH30474A (de)
PT (1) PT678027E (de)
SG (1) SG52359A1 (de)
WO (1) WO1994015612A1 (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6855703B1 (en) * 2000-03-10 2005-02-15 Endeavor Pharmaceuticals Pharmaceutical compositions of conjugated estrogens and methods of analyzing mixtures containing estrogenic compounds

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3436411A (en) 1967-12-28 1969-04-01 American Home Prod Process for cleaving an a-ring ether group in 13-alkylgona (and 8-isogona)-1,3,5(10)-trienes and delta-7-,delta-8(9)-,and delta-8(9),14(15)-dehydro derivatives thereof
US3507889A (en) * 1968-06-11 1970-04-21 American Home Prod Process for the preparation of 17alpha-dihydroequilenin and related compounds
US3608075A (en) * 1969-07-28 1971-09-21 American Home Prod Compositions and methods of treating the menopausal syndrome
US3646076A (en) 1970-06-02 1972-02-29 American Home Prod Process for ethynylating 17-keto steroidal phenols
US4154820A (en) * 1976-02-23 1979-05-15 Akzona Incorporated Compositions containing alkali metal sulfate salts of conjugated estrogens and antioxidants as stabilizers
US4379780A (en) * 1980-09-29 1983-04-12 American Home Products Corporation 17 α-Dihydroequilin hapten and assay method

Also Published As

Publication number Publication date
MX9400254A (es) 1994-08-31
CA2152187A1 (en) 1994-07-21
IL108155A0 (en) 1994-04-12
DE69331237D1 (de) 2002-01-10
JP3344585B2 (ja) 2002-11-11
SG52359A1 (en) 1998-09-28
WO1994015612A1 (en) 1994-07-21
IL108155A (en) 1999-08-17
EP0678027B1 (de) 2001-11-28
AU6015794A (en) 1994-08-15
ES2165382T3 (es) 2002-03-16
PH30474A (en) 1997-05-28
DE69331237T2 (de) 2002-06-13
HK1011282A1 (en) 1999-07-09
CY2361B1 (en) 2004-06-04
CN1071573C (zh) 2001-09-26
JPH08505392A (ja) 1996-06-11
DK0678027T3 (da) 2002-03-18
EP0678027A1 (de) 1995-10-25
CN1096443A (zh) 1994-12-21
PT678027E (pt) 2002-04-29

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee