ATE284710T1 - Adjuvans für vitale impfstoffe - Google Patents
Adjuvans für vitale impfstoffeInfo
- Publication number
- ATE284710T1 ATE284710T1 AT96303835T AT96303835T ATE284710T1 AT E284710 T1 ATE284710 T1 AT E284710T1 AT 96303835 T AT96303835 T AT 96303835T AT 96303835 T AT96303835 T AT 96303835T AT E284710 T1 ATE284710 T1 AT E284710T1
- Authority
- AT
- Austria
- Prior art keywords
- adjuvans
- vaccines
- vital
- adjuvant
- compositions
- Prior art date
Links
- 239000002671 adjuvant Substances 0.000 title abstract 3
- 229960005486 vaccine Drugs 0.000 title abstract 2
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 abstract 3
- 239000000203 mixture Substances 0.000 abstract 2
- YYGNTYWPHWGJRM-UHFFFAOYSA-N (6E,10E,14E,18E)-2,6,10,15,19,23-hexamethyltetracosa-2,6,10,14,18,22-hexaene Chemical compound CC(C)=CCCC(C)=CCCC(C)=CCCC=C(C)CCC=C(C)CCC=C(C)C YYGNTYWPHWGJRM-UHFFFAOYSA-N 0.000 abstract 1
- BHEOSNUKNHRBNM-UHFFFAOYSA-N Tetramethylsqualene Natural products CC(=C)C(C)CCC(=C)C(C)CCC(C)=CCCC=C(C)CCC(C)C(=C)CCC(C)C(C)=C BHEOSNUKNHRBNM-UHFFFAOYSA-N 0.000 abstract 1
- 159000000013 aluminium salts Chemical class 0.000 abstract 1
- 229910000329 aluminium sulfate Inorganic materials 0.000 abstract 1
- 239000000872 buffer Substances 0.000 abstract 1
- PRAKJMSDJKAYCZ-UHFFFAOYSA-N dodecahydrosqualene Natural products CC(C)CCCC(C)CCCC(C)CCCCC(C)CCCC(C)CCCC(C)C PRAKJMSDJKAYCZ-UHFFFAOYSA-N 0.000 abstract 1
- 229940031439 squalene Drugs 0.000 abstract 1
- TUHBEKDERLKLEC-UHFFFAOYSA-N squalene Natural products CC(=CCCC(=CCCC(=CCCC=C(/C)CCC=C(/C)CC=C(C)C)C)C)C TUHBEKDERLKLEC-UHFFFAOYSA-N 0.000 abstract 1
- 239000004094 surface-active agent Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55566—Emulsions, e.g. Freund's adjuvant, MF59
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/459,600 US5718904A (en) | 1995-06-02 | 1995-06-02 | Adjuvants for viral vaccines |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE284710T1 true ATE284710T1 (de) | 2005-01-15 |
Family
ID=23825435
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT96303835T ATE284710T1 (de) | 1995-06-02 | 1996-05-29 | Adjuvans für vitale impfstoffe |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US5718904A (de) |
| EP (1) | EP0745387B1 (de) |
| JP (1) | JP4344017B2 (de) |
| KR (1) | KR970000248A (de) |
| CN (1) | CN1141810A (de) |
| AT (1) | ATE284710T1 (de) |
| AU (1) | AU712972B2 (de) |
| CA (1) | CA2177668C (de) |
| DE (1) | DE69634024T2 (de) |
| DK (1) | DK0745387T3 (de) |
| ES (1) | ES2233955T3 (de) |
| HU (1) | HUP9601466A2 (de) |
| NZ (1) | NZ286699A (de) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PT973546E (pt) * | 1997-04-08 | 2004-06-30 | Merck & Co Inc | Formulacoes estabilizadas de virus de papiloma humano |
| US6165481A (en) * | 1997-12-25 | 2000-12-26 | Nippon Petrochemicals Company, Inc. | Highly pure squalane, raw material for pharmaceuticals and cosmetics prepared by using the same and method for producing the same |
| AU769539B2 (en) | 1999-01-29 | 2004-01-29 | Zoetis Services Llc | Adjuvants for use in vaccines |
| AU2004226591B2 (en) * | 2003-04-04 | 2009-06-04 | Zoetis Services Llc | Microfluidized oil-in-water emulsions and vaccine compositions |
| KR20110132416A (ko) | 2004-04-05 | 2011-12-07 | 화이자 프로덕츠 인코포레이티드 | 미세유체화된 수중유 유화액 및 백신 조성물 |
| CN1315533C (zh) * | 2004-06-24 | 2007-05-16 | 上海市农业科学院畜牧兽医研究所 | 猪细小病毒油乳剂灭活疫苗 |
| US20060228369A1 (en) * | 2005-04-11 | 2006-10-12 | Program For Appropriate Technology In Health | Stabilization and preservation of temperature-sensitive vaccines |
| DK1909830T3 (da) * | 2005-08-02 | 2011-12-19 | Novartis Vaccines & Diagnostic | Formindskelse af interferens mellem olieholdige adjuvanser og antigener indeholdende overfladeaktivt middel |
| FR2896162B1 (fr) * | 2006-01-13 | 2008-02-15 | Sanofi Pasteur Sa | Emulsion huile dans eau thermoreversible |
| CA2634888C (en) * | 2006-01-26 | 2016-06-21 | Pfizer Products Inc. | Novel glycolipid adjuvant compositions |
| US7682619B2 (en) * | 2006-04-06 | 2010-03-23 | Cornell Research Foundation, Inc. | Canine influenza virus |
| ITFI20060163A1 (it) * | 2006-06-29 | 2006-09-28 | Menarini Internat Operations Luxembourg Sa | Composizione farmaceutica contenente un anticorpo monoclonale anti idiotipico anti-ca-125 ed alluminio |
| PL2068918T5 (pl) | 2006-09-26 | 2024-12-02 | Access To Advanced Health Institute | Kompozycja szczepionki zawierająca syntetyczny adiuwant |
| US20090181078A1 (en) | 2006-09-26 | 2009-07-16 | Infectious Disease Research Institute | Vaccine composition containing synthetic adjuvant |
| GB0622282D0 (en) | 2006-11-08 | 2006-12-20 | Novartis Ag | Quality control methods |
| CA2764374C (en) | 2009-06-05 | 2019-11-19 | Infectious Disease Research Institute | Synthetic glucopyranosyl lipid adjuvants |
| US20110305748A1 (en) | 2010-03-11 | 2011-12-15 | Immune Design, Corp. | Vaccines for Pandemic Influenza |
| EA027236B1 (ru) | 2011-04-08 | 2017-07-31 | Иммьюн Дизайн Корп. | Иммуногенные композиции и способы применения таких композиций для индукции гуморального и клеточного иммунного ответа |
| US20120288515A1 (en) | 2011-04-27 | 2012-11-15 | Immune Design Corp. | Synthetic long peptide (slp)-based vaccines |
| HRP20181102T1 (hr) | 2012-05-16 | 2018-09-07 | Immune Design Corp | Cjepiva za hsv-2 |
| CN102764431B (zh) * | 2012-08-03 | 2014-10-22 | 江苏省农业科学院 | 一种猪支原体肺炎雾化活疫苗及其制备与检验方法 |
| CN104043119B (zh) * | 2013-03-13 | 2016-05-25 | 上海医药工业研究院 | 一种新型疫苗佐剂及其制备方法 |
| MX370573B (es) | 2013-04-18 | 2019-12-17 | Immune Design Corp | Monoterapia con glucopiranosil lipido a para usarse en el tratamiento del cancer. |
| US9463198B2 (en) | 2013-06-04 | 2016-10-11 | Infectious Disease Research Institute | Compositions and methods for reducing or preventing metastasis |
| US10653766B2 (en) | 2014-03-12 | 2020-05-19 | Bavarian Nordic A/S | Use of oil and water emulsions for increasing B cell responses with modified Vaccinia Ankara virus |
| EP3843782A1 (de) | 2018-08-29 | 2021-07-07 | Centre Hospitalier Universitaire Vaudois (CHUV) | Ebolaimpfstoffzusammensetzungen und verfahren zu ihrer verwendung |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4073743A (en) * | 1975-04-17 | 1978-02-14 | Merck & Co., Inc. | Process for preparing an emulsion |
| US4466957A (en) * | 1982-02-25 | 1984-08-21 | American Home Products Corporation | Vaccine adjuvants |
| DE3446515A1 (de) * | 1984-12-20 | 1986-06-26 | Behringwerke Ag, 3550 Marburg | Oeladjuvierte vaccine und verfahren zu ihrer herstellung |
| US4806352A (en) * | 1986-04-15 | 1989-02-21 | Ribi Immunochem Research Inc. | Immunological lipid emulsion adjuvant |
| US4803070A (en) * | 1986-04-15 | 1989-02-07 | Ribi Immunochem Research Inc. | Immunological emulsion adjuvants for polysaccharide vaccines |
| US5376369A (en) * | 1987-11-03 | 1994-12-27 | Syntex (U.S.A.) Inc. | Vaccine adjuvant |
| CA2017507C (en) * | 1989-05-25 | 1996-11-12 | Gary Van Nest | Adjuvant formulation comprising a submicron oil droplet emulsion |
-
1995
- 1995-06-02 US US08/459,600 patent/US5718904A/en not_active Expired - Lifetime
-
1996
- 1996-05-16 JP JP12143896A patent/JP4344017B2/ja not_active Expired - Lifetime
- 1996-05-29 AT AT96303835T patent/ATE284710T1/de active
- 1996-05-29 ES ES96303835T patent/ES2233955T3/es not_active Expired - Lifetime
- 1996-05-29 CA CA002177668A patent/CA2177668C/en not_active Expired - Lifetime
- 1996-05-29 AU AU54575/96A patent/AU712972B2/en not_active Expired
- 1996-05-29 DK DK96303835T patent/DK0745387T3/da active
- 1996-05-29 EP EP96303835A patent/EP0745387B1/de not_active Revoked
- 1996-05-29 DE DE69634024T patent/DE69634024T2/de not_active Expired - Lifetime
- 1996-05-30 NZ NZ286699A patent/NZ286699A/en not_active IP Right Cessation
- 1996-05-30 HU HU9601466A patent/HUP9601466A2/hu unknown
- 1996-05-31 KR KR1019960018975A patent/KR970000248A/ko not_active Ceased
- 1996-06-01 CN CN96110402A patent/CN1141810A/zh active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| CN1141810A (zh) | 1997-02-05 |
| JP4344017B2 (ja) | 2009-10-14 |
| CA2177668A1 (en) | 1996-12-03 |
| EP0745387A2 (de) | 1996-12-04 |
| HUP9601466A2 (en) | 1997-03-28 |
| KR970000248A (ko) | 1997-01-21 |
| DE69634024T2 (de) | 2005-12-08 |
| HU9601466D0 (en) | 1996-07-29 |
| CA2177668C (en) | 2009-02-24 |
| EP0745387A3 (de) | 1998-03-11 |
| NZ286699A (en) | 1997-10-24 |
| US5718904A (en) | 1998-02-17 |
| AU5457596A (en) | 1996-12-12 |
| EP0745387B1 (de) | 2004-12-15 |
| DK0745387T3 (da) | 2005-02-21 |
| JPH08325163A (ja) | 1996-12-10 |
| ES2233955T3 (es) | 2005-06-16 |
| DE69634024D1 (de) | 2005-01-20 |
| AU712972B2 (en) | 1999-11-18 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
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