ATE285763T1 - Verwendung von gabab-rezeptor agonisten und deren pharmazeutisch akzeptierbaren derivate bei der therapie zur erhaltung von nikotinabstinenz bei nikotinabhängigen patienten - Google Patents

Verwendung von gabab-rezeptor agonisten und deren pharmazeutisch akzeptierbaren derivate bei der therapie zur erhaltung von nikotinabstinenz bei nikotinabhängigen patienten

Info

Publication number
ATE285763T1
ATE285763T1 AT00947901T AT00947901T ATE285763T1 AT E285763 T1 ATE285763 T1 AT E285763T1 AT 00947901 T AT00947901 T AT 00947901T AT 00947901 T AT00947901 T AT 00947901T AT E285763 T1 ATE285763 T1 AT E285763T1
Authority
AT
Austria
Prior art keywords
nicotine
therapy
pharmaceutically acceptable
acceptable derivatives
maintaining
Prior art date
Application number
AT00947901T
Other languages
English (en)
Inventor
Gian Luigi Gessa
Giancarlo Colombo
Luca Pani
Walter Fratta
Original Assignee
Molteni & C
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Molteni & C filed Critical Molteni & C
Application granted granted Critical
Publication of ATE285763T1 publication Critical patent/ATE285763T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/662—Phosphorus acids or esters thereof having P—C bonds, e.g. foscarnet, trichlorfon
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/34—Tobacco-abuse

Landscapes

  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Addiction (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
AT00947901T 1999-07-30 2000-06-30 Verwendung von gabab-rezeptor agonisten und deren pharmazeutisch akzeptierbaren derivate bei der therapie zur erhaltung von nikotinabstinenz bei nikotinabhängigen patienten ATE285763T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT1999MI001715A IT1313585B1 (it) 1999-07-30 1999-07-30 Uso di agonisti dei recettori gabab per la terapia di mantenimentodell'astinenza da nicotina in soggetti nicotino-dipendenti.
PCT/EP2000/006120 WO2001008675A1 (en) 1999-07-30 2000-06-30 Use of agonists of gabab receptors and pharmaceutically acceptable derivates thereof, in the therapy of maintaining nicotine abstinence-dependent patients

Publications (1)

Publication Number Publication Date
ATE285763T1 true ATE285763T1 (de) 2005-01-15

Family

ID=11383467

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00947901T ATE285763T1 (de) 1999-07-30 2000-06-30 Verwendung von gabab-rezeptor agonisten und deren pharmazeutisch akzeptierbaren derivate bei der therapie zur erhaltung von nikotinabstinenz bei nikotinabhängigen patienten

Country Status (16)

Country Link
EP (1) EP1202727B1 (de)
CN (1) CN1176650C (de)
AT (1) ATE285763T1 (de)
AU (1) AU6153400A (de)
CA (1) CA2379752C (de)
DE (1) DE60017147T2 (de)
DK (1) DK1202727T3 (de)
ES (1) ES2235913T3 (de)
HK (1) HK1046849B (de)
IL (2) IL147876A0 (de)
IT (1) IT1313585B1 (de)
PL (1) PL196334B1 (de)
PT (1) PT1202727E (de)
RU (1) RU2262352C2 (de)
SI (1) SI1202727T1 (de)
WO (1) WO2001008675A1 (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2354120A1 (de) 2003-08-20 2011-08-10 XenoPort, Inc. Synthese von Acyloxyalkylcarbamat-Prodrugs und Zwischenprodukten davon
AU2004267100B2 (en) * 2003-08-20 2010-10-07 Xenoport, Inc. Acyloxyalkyl carbamate prodrugs, methods of synthesis and use
US7566738B2 (en) 2004-11-03 2009-07-28 Xenoport, Inc. Acyloxyalkyl carbamate prodrugs of sulfinic acids, methods of synthesis, and use
US7494985B2 (en) 2004-11-03 2009-02-24 Xenoport, Inc. Acyloxyalkyl carbamate prodrugs, methods of synthesis, and use
WO2008033572A1 (en) 2006-09-15 2008-03-20 Xenoport, Inc. Acyloxyalkyl carbamate prodrugs, methods of synthesis and use
JP4498407B2 (ja) 2006-12-22 2010-07-07 キヤノン株式会社 プロセスカートリッジ、電子写真画像形成装置、及び、電子写真感光体ドラムユニット
WO2009094563A2 (en) 2008-01-25 2009-07-30 Xenoport, Inc. Crystalline form of calcium-salts of (3s)-aminomethyl-b-methyl-hexanoic acids and methods of use
CA2710538A1 (en) 2008-01-25 2009-07-30 Xenoport, Inc. Crystalline form of a (3s)-aminomethyl-5-methyl-hexanoic acid prodrug and methods of use
WO2009094577A2 (en) 2008-01-25 2009-07-30 Xenoport, Inc. Mesophasic forms of (3s)-aminomethyl-5-methyl-hexanoic acid prodrugs and methods of use
WO2010017504A1 (en) 2008-08-07 2010-02-11 Xenoport, Inc. Methods of synthesizing 1-(acyloxy)-alkyl carbamate prodrugs
WO2010017498A1 (en) 2008-08-07 2010-02-11 Xenoport, Inc. Methods of synthesizing n-hydroxysuccinimidyl carbonates
US10071068B2 (en) 2009-03-03 2018-09-11 Xenoport, Inc. Sustained release oral dosage forms of an R-baclofen prodrug
EP2419401A2 (de) 2009-04-17 2012-02-22 XenoPort, Inc. Gamma-aminobuttersäurederivate als gabab-rezeptorliganden
WO2011081558A1 (ru) * 2009-08-21 2011-07-07 Komissarov Jury Vladimirovich Курительное устройство для отказа от табачного курения
US8580850B2 (en) 2011-08-11 2013-11-12 Xenoport, Inc. Anhydrous and hemihydrate crystalline forms of an (R)-baclofen prodrug, methods of synthesis and methods of use
EP3761979A4 (de) * 2018-04-06 2021-06-30 Ovid Therapeutics Inc. Verwendung von gaboxadol zur behandlung von substanzmissbrauch

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4126684A (en) * 1976-02-11 1978-11-21 Ciba-Geigy Corporation 4-amino-3-p-halophenylbutyric acids and their derivatives used in the control of narcotic abuse
US5073539A (en) * 1990-01-22 1991-12-17 Ciba-Geigy Corporation Transdermal administration of zwitterionic drugs
US5760049A (en) * 1997-02-21 1998-06-02 Synapse Pharmaceuticals International, Inc. Method for controlling tobacco use and alleviating withdrawal symptoms due to cessation of tobacco use
US6541520B1 (en) * 1998-08-05 2003-04-01 Brookhaven Science Associates Treatment of addiction and addiction-related behavior
RU2132203C1 (ru) * 1998-09-03 1999-06-27 Шакирзянов Галимзян Закирович Способ лечения табачной зависимости и антитабачный комбинированный препарат

Also Published As

Publication number Publication date
IL147876A0 (en) 2002-08-14
PT1202727E (pt) 2005-05-31
AU6153400A (en) 2001-02-19
WO2001008675A1 (en) 2001-02-08
DK1202727T3 (da) 2005-05-09
EP1202727A1 (de) 2002-05-08
CN1176650C (zh) 2004-11-24
ITMI991715A1 (it) 2001-01-30
DE60017147T2 (de) 2006-01-12
HK1046849A1 (en) 2003-01-30
IL147876A (en) 2007-06-17
PL353373A1 (en) 2003-11-17
ITMI991715A0 (it) 1999-07-30
CA2379752A1 (en) 2001-02-08
ES2235913T3 (es) 2005-07-16
CN1377265A (zh) 2002-10-30
RU2262352C2 (ru) 2005-10-20
SI1202727T1 (de) 2005-08-31
EP1202727B1 (de) 2004-12-29
HK1046849B (en) 2005-07-15
IT1313585B1 (it) 2002-09-09
CA2379752C (en) 2008-05-27
PL196334B1 (pl) 2007-12-31
DE60017147D1 (de) 2005-02-03

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