ATE285785T1 - Hgf mutant und dessen verwendung als antikrebsmittel - Google Patents
Hgf mutant und dessen verwendung als antikrebsmittelInfo
- Publication number
- ATE285785T1 ATE285785T1 AT96935432T AT96935432T ATE285785T1 AT E285785 T1 ATE285785 T1 AT E285785T1 AT 96935432 T AT96935432 T AT 96935432T AT 96935432 T AT96935432 T AT 96935432T AT E285785 T1 ATE285785 T1 AT E285785T1
- Authority
- AT
- Austria
- Prior art keywords
- alpha
- hgf
- fragment
- active ingredient
- anticancer agent
- Prior art date
Links
- 239000002246 antineoplastic agent Substances 0.000 title abstract 3
- 102000003745 Hepatocyte Growth Factor Human genes 0.000 abstract 3
- 108090000100 Hepatocyte Growth Factor Proteins 0.000 abstract 3
- 206010028980 Neoplasm Diseases 0.000 abstract 2
- 239000004480 active ingredient Substances 0.000 abstract 2
- 210000004027 cell Anatomy 0.000 abstract 2
- 239000012634 fragment Substances 0.000 abstract 2
- 208000022072 Gallbladder Neoplasms Diseases 0.000 abstract 1
- 206010027476 Metastases Diseases 0.000 abstract 1
- 239000005557 antagonist Substances 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 210000000232 gallbladder Anatomy 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 230000009545 invasion Effects 0.000 abstract 1
- 231100000225 lethality Toxicity 0.000 abstract 1
- 208000020816 lung neoplasm Diseases 0.000 abstract 1
- 230000009401 metastasis Effects 0.000 abstract 1
- 230000001394 metastastic effect Effects 0.000 abstract 1
- 206010061289 metastatic neoplasm Diseases 0.000 abstract 1
- 238000011275 oncology therapy Methods 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
- A61K38/1833—Hepatocyte growth factor; Scatter factor; Tumor cytotoxic factor II
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Gastroenterology & Hepatology (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP30072895A JP3832674B2 (ja) | 1995-10-24 | 1995-10-24 | 抗癌剤 |
| PCT/JP1996/003105 WO1997016205A1 (fr) | 1995-10-24 | 1996-10-23 | Agent antitumoral |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE285785T1 true ATE285785T1 (de) | 2005-01-15 |
Family
ID=17888391
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT96935432T ATE285785T1 (de) | 1995-10-24 | 1996-10-23 | Hgf mutant und dessen verwendung als antikrebsmittel |
Country Status (7)
| Country | Link |
|---|---|
| EP (1) | EP0890361B1 (de) |
| JP (1) | JP3832674B2 (de) |
| AT (1) | ATE285785T1 (de) |
| CA (1) | CA2235805C (de) |
| DE (1) | DE69634138T2 (de) |
| ES (1) | ES2235200T3 (de) |
| WO (1) | WO1997016205A1 (de) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6346510B1 (en) | 1995-10-23 | 2002-02-12 | The Children's Medical Center Corporation | Therapeutic antiangiogenic endostatin compositions |
| AU784359B2 (en) * | 1999-12-15 | 2006-03-16 | Entremed, Inc | Compositions and methods for inhibiting endothelial cell proliferation |
| EP1320384B1 (de) | 2000-08-28 | 2007-10-10 | Damavand Wound AB | Die synergistischen wirkungen von hgf und antibakterieller behandlung |
| US20030118585A1 (en) | 2001-10-17 | 2003-06-26 | Agy Therapeutics | Use of protein biomolecular targets in the treatment and visualization of brain tumors |
| CA2548282A1 (en) * | 2003-12-11 | 2005-06-30 | Genentech, Inc. | Methods and compositions for inhibiting c-met dimerization and activation |
| WO2007110698A2 (en) * | 2005-11-16 | 2007-10-04 | Fariba Nayeri | Methods for inhibiting carcinogenesis and/or metastasis in an individual with endogenous c-met ligands and inhibitors |
| WO2009125831A1 (ja) * | 2008-04-11 | 2009-10-15 | 有限会社スリーピー | Nk4に対するモノクローナル抗体 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6566098B1 (en) * | 1990-09-14 | 2003-05-20 | The United States Of America As Represented By The Department Of Health And Human Services | DNA encoding truncated hepatocyte growth factor variants |
| JP3030386B2 (ja) * | 1991-05-15 | 2000-04-10 | 敏一 中村 | 抗ガン剤 |
| ATE222603T1 (de) * | 1992-05-18 | 2002-09-15 | Genentech Inc | Hepatozytwachstumfaktor variante |
| ATE160585T1 (de) * | 1992-09-18 | 1997-12-15 | Us Gov Health & Human Serv | Eine methode zur herstellung von hepatozytwachstumsfaktor und eine zelllinie |
-
1995
- 1995-10-24 JP JP30072895A patent/JP3832674B2/ja not_active Expired - Fee Related
-
1996
- 1996-10-23 DE DE69634138T patent/DE69634138T2/de not_active Expired - Lifetime
- 1996-10-23 AT AT96935432T patent/ATE285785T1/de not_active IP Right Cessation
- 1996-10-23 EP EP96935432A patent/EP0890361B1/de not_active Expired - Lifetime
- 1996-10-23 CA CA002235805A patent/CA2235805C/en not_active Expired - Fee Related
- 1996-10-23 WO PCT/JP1996/003105 patent/WO1997016205A1/ja not_active Ceased
- 1996-10-23 ES ES96935432T patent/ES2235200T3/es not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| DE69634138D1 (de) | 2005-02-03 |
| EP0890361A4 (de) | 2001-04-11 |
| JPH09110716A (ja) | 1997-04-28 |
| ES2235200T3 (es) | 2005-07-01 |
| DE69634138T2 (de) | 2006-02-09 |
| WO1997016205A1 (fr) | 1997-05-09 |
| CA2235805C (en) | 2008-10-28 |
| EP0890361A1 (de) | 1999-01-13 |
| CA2235805A1 (en) | 1997-05-09 |
| EP0890361B1 (de) | 2004-12-29 |
| JP3832674B2 (ja) | 2006-10-11 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |