ATE286143T1 - Verfahren zur herstellung eines diagnostischen standard-gentranskriptionsmusters - Google Patents

Verfahren zur herstellung eines diagnostischen standard-gentranskriptionsmusters

Info

Publication number
ATE286143T1
ATE286143T1 AT98919350T AT98919350T ATE286143T1 AT E286143 T1 ATE286143 T1 AT E286143T1 AT 98919350 T AT98919350 T AT 98919350T AT 98919350 T AT98919350 T AT 98919350T AT E286143 T1 ATE286143 T1 AT E286143T1
Authority
AT
Austria
Prior art keywords
producing
standard diagnostic
diagnostic gene
gene transcription
disease
Prior art date
Application number
AT98919350T
Other languages
English (en)
Inventor
Praveen Sharma
Anders Loenneborg
Original Assignee
Diagenic As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Diagenic As filed Critical Diagenic As
Application granted granted Critical
Publication of ATE286143T1 publication Critical patent/ATE286143T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6809—Methods for determination or identification of nucleic acids involving differential detection
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6816—Hybridisation assays characterised by the detection means

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
AT98919350T 1997-04-30 1998-04-30 Verfahren zur herstellung eines diagnostischen standard-gentranskriptionsmusters ATE286143T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
NO972006A NO972006D0 (no) 1997-04-30 1997-04-30 Ny metode for diagnose av sykdommer
PCT/GB1998/001261 WO1998049342A1 (en) 1997-04-30 1998-04-30 Method of preparing a standard diagnostic gene transcript pattern

Publications (1)

Publication Number Publication Date
ATE286143T1 true ATE286143T1 (de) 2005-01-15

Family

ID=19900683

Family Applications (2)

Application Number Title Priority Date Filing Date
AT98919350T ATE286143T1 (de) 1997-04-30 1998-04-30 Verfahren zur herstellung eines diagnostischen standard-gentranskriptionsmusters
AT03075068T ATE412003T1 (de) 1997-04-30 1998-04-30 Verfahren zur diagnose der alzheimer erkrankung auf der basis eines gen transkriptionsmusters

Family Applications After (1)

Application Number Title Priority Date Filing Date
AT03075068T ATE412003T1 (de) 1997-04-30 1998-04-30 Verfahren zur diagnose der alzheimer erkrankung auf der basis eines gen transkriptionsmusters

Country Status (13)

Country Link
US (4) US6720138B2 (de)
EP (3) EP2050825A1 (de)
JP (1) JP4163758B2 (de)
AT (2) ATE286143T1 (de)
AU (1) AU7222698A (de)
CY (1) CY1108716T1 (de)
DE (2) DE69828392T2 (de)
DK (2) DK1323728T3 (de)
ES (2) ES2316693T3 (de)
HK (1) HK1026003A1 (de)
NO (2) NO972006D0 (de)
PT (2) PT979308E (de)
WO (1) WO1998049342A1 (de)

Families Citing this family (81)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NO972006D0 (no) * 1997-04-30 1997-04-30 Forskningsparken I Aas As Ny metode for diagnose av sykdommer
US20070031841A1 (en) * 2001-02-28 2007-02-08 Choong-Chin Liew Method for the detection of gene transcripts in blood and uses thereof
US20050003394A1 (en) * 1999-01-06 2005-01-06 Chondrogene Limited Method for the detection of rheumatoid arthritis related gene transcripts in blood
US20060134635A1 (en) * 2001-02-28 2006-06-22 Chondrogene Limited Method for the detection of coronary artery disease related gene transcripts in blood
WO2000040749A2 (en) * 1999-01-06 2000-07-13 Genenews Inc. Method for the detection of gene transcripts in blood and uses thereof
US20040241726A1 (en) * 1999-01-06 2004-12-02 Chondrogene Limited Method for the detection of allergies related gene transcripts in blood
US20040248169A1 (en) * 1999-01-06 2004-12-09 Chondrogene Limited Method for the detection of obesity related gene transcripts in blood
US7473528B2 (en) 1999-01-06 2009-01-06 Genenews Inc. Method for the detection of Chagas disease related gene transcripts in blood
US20040241728A1 (en) * 1999-01-06 2004-12-02 Chondrogene Limited Method for the detection of lung disease related gene transcripts in blood
US20050123938A1 (en) * 1999-01-06 2005-06-09 Chondrogene Limited Method for the detection of osteoarthritis related gene transcripts in blood
US20040265868A1 (en) * 1999-01-06 2004-12-30 Chondrogene Limited Method for the detection of depression related gene transcripts in blood
US20040248170A1 (en) * 1999-01-06 2004-12-09 Chondrogene Limited Method for the detection of hyperlipidemia related gene transcripts in blood
US6365376B1 (en) * 1999-02-19 2002-04-02 E. I. Du Pont De Nemours And Company Genes and enzymes for the production of adipic acid intermediates
AU782926B2 (en) * 1999-03-10 2005-09-08 Cold Spring Harbor Laboratory Gene chip technology for determining memory genes
US7005256B1 (en) 1999-03-10 2006-02-28 Cold Spring Harbor Laboratory Gene chip technology for determining memory genes
EP1208228A2 (de) * 1999-05-19 2002-05-29 Mitokor Differentielle genexpression in spezifischen regionen vom gehirn in neurodegenerativen erkrankungen
PT1410011E (pt) 2001-06-18 2011-07-25 Rosetta Inpharmatics Llc Diagnóstico e prognóstico de pacientes com cancro da mama
US20050064446A1 (en) * 2001-11-01 2005-03-24 Minerva Biotechnologies Corporation Detection of binding species with colloidal and non-colloidal structures
GB0227238D0 (en) * 2002-11-21 2002-12-31 Diagenic As Product and method
US7217807B2 (en) * 2002-11-26 2007-05-15 Rosetta Genomics Ltd Bioinformatically detectable group of novel HIV regulatory genes and uses thereof
FR2853907B1 (fr) * 2003-04-18 2007-08-03 Commissariat Energie Atomique Procede de preparation de fragments d'adn par fragmentation selective d'acides nucleiques et ses applications
US7888497B2 (en) * 2003-08-13 2011-02-15 Rosetta Genomics Ltd. Bioinformatically detectable group of novel regulatory oligonucleotides and uses thereof
WO2005076939A2 (en) * 2004-02-09 2005-08-25 University Of Kentucky Research Foundation Assay and method for diagnosing and treating alzheimer’s disease
US7593483B2 (en) * 2004-05-07 2009-09-22 Broadcom Corporation Nonlinear mapping in digital-to-analog and analog-to-digital converters
US7687616B1 (en) 2004-05-14 2010-03-30 Rosetta Genomics Ltd Small molecules modulating activity of micro RNA oligonucleotides and micro RNA targets and uses thereof
CA2566519C (en) 2004-05-14 2020-04-21 Rosetta Genomics Ltd. Micrornas and uses thereof
US7795419B2 (en) * 2004-05-26 2010-09-14 Rosetta Genomics Ltd. Viral and viral associated miRNAs and uses thereof
EP2471924A1 (de) 2004-05-28 2012-07-04 Asuragen, INC. Verfahren und Zusammensetzungen mit microRNA
GB0412301D0 (en) * 2004-06-02 2004-07-07 Diagenic As Product and method
US7867703B2 (en) * 2004-08-26 2011-01-11 Agilent Technologies, Inc. Element defined sequence complexity reduction
US7713693B1 (en) 2004-09-01 2010-05-11 University Of Louisiana At Monroe Human cancer cell specific gene transcript
ES2534300T3 (es) 2004-11-12 2015-04-21 Asuragen, Inc. Procedimientos y composiciones que implican miARN y moléculas inhibidoras de miARN
CN103497993A (zh) * 2005-02-07 2014-01-08 基因信息公司 轻度骨关节炎生物标志物及其用途
US20070082350A1 (en) * 2005-02-09 2007-04-12 Philip Landfield Assay and method for diagnosing and treating alzheimer's disease
US20080075789A1 (en) * 2006-02-28 2008-03-27 The Regents Of The University Of California Genes differentially expressed in bipolar disorder and/or schizophrenia
CA2664383C (en) 2006-09-19 2017-08-22 Asuragen, Inc. Micrornas differentially expressed in pancreatic diseases and uses thereof
EP2145001A2 (de) 2006-09-19 2010-01-20 Asuragen, Inc. Von mir-15, mir-26, mir -31,mir -145, mir-147, mir-188, mir-215, mir-216 mir-331, mmu-mir-292-3p regulierte gene und stoffwechselwege als ziele für einen therapeutischen eingriff
US20090029868A1 (en) * 2006-10-31 2009-01-29 Applera Corporation Expression signature in peripheral blood for detection of aortic aneurysm
WO2008073919A2 (en) * 2006-12-08 2008-06-19 Asuragen, Inc. Mir-20 regulated genes and pathways as targets for therapeutic intervention
EP2104737B1 (de) * 2006-12-08 2013-04-10 Asuragen, INC. Funktionen und ziele von let-7-mikro-rnas
CN101622348A (zh) * 2006-12-08 2010-01-06 奥斯瑞根公司 作为治疗性干预靶标的miR-20调节的基因和途径
EP2104735A2 (de) * 2006-12-08 2009-09-30 Asuragen, INC. Mir-21-regulierte gene und pfade als ziele für therapeutische interventionen
CA2671270A1 (en) * 2006-12-29 2008-07-17 Asuragen, Inc. Mir-16 regulated genes and pathways as targets for therapeutic intervention
US20090232893A1 (en) * 2007-05-22 2009-09-17 Bader Andreas G miR-143 REGULATED GENES AND PATHWAYS AS TARGETS FOR THERAPEUTIC INTERVENTION
AU2008261951A1 (en) * 2007-06-08 2008-12-18 Asuragen, Inc. miR-34 regulated genes and pathways as targets for therapeutic intervention
US8361714B2 (en) 2007-09-14 2013-01-29 Asuragen, Inc. Micrornas differentially expressed in cervical cancer and uses thereof
WO2009052386A1 (en) * 2007-10-18 2009-04-23 Asuragen, Inc. Micrornas differentially expressed in lung diseases and uses thereof
WO2009070805A2 (en) * 2007-12-01 2009-06-04 Asuragen, Inc. Mir-124 regulated genes and pathways as targets for therapeutic intervention
US20090192114A1 (en) * 2007-12-21 2009-07-30 Dmitriy Ovcharenko miR-10 Regulated Genes and Pathways as Targets for Therapeutic Intervention
WO2009100430A2 (en) * 2008-02-08 2009-08-13 Asuragen, Inc miRNAs DIFFERENTIALLY EXPRESSED IN LYMPH NODES FROM CANCER PATIENTS
US20090253780A1 (en) * 2008-03-26 2009-10-08 Fumitaka Takeshita COMPOSITIONS AND METHODS RELATED TO miR-16 AND THERAPY OF PROSTATE CANCER
WO2009126726A1 (en) * 2008-04-08 2009-10-15 Asuragen, Inc Methods and compositions for diagnosing and modulating human papillomavirus (hpv)
US8258111B2 (en) * 2008-05-08 2012-09-04 The Johns Hopkins University Compositions and methods related to miRNA modulation of neovascularization or angiogenesis
CA2728171A1 (en) * 2008-08-27 2010-03-04 H. Lundbeck A/S System and methods for measuring biomarker profiles
US20100179213A1 (en) * 2008-11-11 2010-07-15 Mirna Therapeutics, Inc. Methods and Compositions Involving miRNAs In Cancer Stem Cells
GB201000688D0 (en) 2010-01-15 2010-03-03 Diagenic Asa Product and method
EP3214174B1 (de) 2010-03-04 2019-10-16 InteRNA Technologies B.V. Mirna-molekül, das über seine quelle definiert ist, und seine diagnostischen und therapeutischen verwendungen bei mit emt assoziierten krankheiten
EP2591106A1 (de) 2010-07-06 2013-05-15 InteRNA Technologies B.V. Mirna und ihre diagnostischen und therapeutischen verwendungen für mit melanomen assoziierte erkrankungen oder leiden oder für mit dem aktivierten braf-pfad assoziierte erkrankungen oder leiden
JP6155194B2 (ja) 2010-11-17 2017-06-28 インターペース ダイアグノスティックス リミテッド ライアビリティ カンパニー 良性甲状腺新生物と悪性甲状腺新生物を区別するためのバイオマーカーとしてのｍｉＲＮＡ
EP2474617A1 (de) 2011-01-11 2012-07-11 InteRNA Technologies BV MIR zur Behandlung von Neoangiogenese
US9222085B2 (en) 2011-02-03 2015-12-29 Mirna Therapeutics, Inc. Synthetic mimics of MIR-124
US20140057295A1 (en) 2011-02-28 2014-02-27 Barbara J. Stegmann Anti-mullerian hormone changes in pregnancy and prediction of adverse pregnancy outcomes and gender
US9746458B2 (en) * 2011-04-27 2017-08-29 Loma Linda University Medical Center Dynactin subunit p62 biomarker for neurological conditions
US9644241B2 (en) 2011-09-13 2017-05-09 Interpace Diagnostics, Llc Methods and compositions involving miR-135B for distinguishing pancreatic cancer from benign pancreatic disease
WO2013063519A1 (en) 2011-10-26 2013-05-02 Asuragen, Inc. Methods and compositions involving mirna expression levels for distinguishing pancreatic cysts
WO2013063544A1 (en) 2011-10-27 2013-05-02 Asuragen, Inc. Mirnas as diagnostic biomarkers to distinguish benign from malignant thyroid tumors
WO2013064702A2 (en) 2011-11-03 2013-05-10 Diagenic Asa Probes for diagnosis and monitoring of neurodegenerative disease
US20150152499A1 (en) 2012-07-03 2015-06-04 Interna Technologies B.V. Diagnostic portfolio and its uses
US20140100124A1 (en) 2012-10-04 2014-04-10 Asuragen, Inc. Diagnostic mirnas for differential diagnosis of incidental pancreatic cystic lesions
WO2014145612A1 (en) 2013-03-15 2014-09-18 Ajay Goel Tissue and blood-based mirna biomarkers for the diagnosis, prognosis and metastasis-predictive potential in colorectal cancer
ES2935257T3 (es) 2013-03-15 2023-03-03 Univ Chicago Métodos y composiciones relacionadas con la actividad de las células T
WO2014151551A1 (en) 2013-03-15 2014-09-25 Baylor Research Institute Ulcerative colitis (uc)-associated colorectal neoplasia markers
AU2018358016A1 (en) 2017-11-03 2020-05-07 Interna Technologies B.V. MiRNA molecule, equivalent, antagomir, or source thereof for treating and/or diagnosing a condition and/or a disease associated with neuronal deficiency or for neuronal (re)generation
EP3714053B1 (de) 2017-11-22 2025-12-31 The University of Chicago Von chemischer sonde abhängige bewertung der proteinaktivität und verwendung davon
CN114174532A (zh) 2019-04-05 2022-03-11 德克萨斯大学系统董事会 细胞条形码编码的方法和应用
EP3952849B1 (de) 2019-04-12 2024-09-18 The Regents Of The University Of California Zusammensetzungen und verfahren zur erhöhung der muskelmasse und des oxidativen stoffwechsels
US12551669B2 (en) 2020-07-15 2026-02-17 Biogen Ma Inc. Medical system including two access ports
IL299904B1 (en) 2020-07-20 2026-05-01 Cerebral Therapeutics Inc Liquid catheter device for recording brain status
US12605537B2 (en) 2022-02-15 2026-04-21 Biogen Ma Inc. Implantable medical device for use with or having recording electrode
WO2024028794A1 (en) 2022-08-02 2024-02-08 Temple Therapeutics BV Methods for treating endometrial and ovarian hyperproliferative disorders
WO2025248505A1 (en) 2024-05-31 2025-12-04 Wayne State University Methods for treating endometrial and ovarian hyperproliferative disorders

Family Cites Families (47)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4981783A (en) 1986-04-16 1991-01-01 Montefiore Medical Center Method for detecting pathological conditions
US6040138A (en) 1995-09-15 2000-03-21 Affymetrix, Inc. Expression monitoring by hybridization to high density oligonucleotide arrays
US5800992A (en) 1989-06-07 1998-09-01 Fodor; Stephen P.A. Method of detecting nucleic acids
US5925525A (en) 1989-06-07 1999-07-20 Affymetrix, Inc. Method of identifying nucleotide differences
US5871928A (en) 1989-06-07 1999-02-16 Fodor; Stephen P. A. Methods for nucleic acid analysis
JP2802125B2 (ja) 1989-06-23 1998-09-24 キヤノン株式会社 核酸の検出方法
US5614192A (en) * 1989-07-19 1997-03-25 Connective Therapeutics, Inc. T cell receptor peptides as therapeutics for immune-related disease
US5474796A (en) * 1991-09-04 1995-12-12 Protogene Laboratories, Inc. Method and apparatus for conducting an array of chemical reactions on a support surface
DK0534640T3 (de) * 1991-09-23 1997-03-17 Pfizer
GB2260811B (en) 1991-10-23 1995-07-05 Yorkshire Cancer Research Camp Detection of malignant tumours
EP0631623A4 (de) 1992-03-04 1996-09-25 Synaptic Pharma Corp Dna kodierend für taurin und gaba transportern und ihre verwendungen.
US6114114A (en) * 1992-07-17 2000-09-05 Incyte Pharmaceuticals, Inc. Comparative gene transcript analysis
EP0667920B1 (de) * 1992-10-29 2003-01-15 Thomas Jefferson University Methoden zur detektion von mikrometastasen bei prostata-krebs
US5633137A (en) 1992-12-01 1997-05-27 The University Of South Florida Method for measuring specific gene expression: transcriptional activity per gene dose
US5677125A (en) 1994-01-14 1997-10-14 Vanderbilt University Method of detection and diagnosis of pre-invasive cancer
WO1997027317A1 (en) 1996-01-23 1997-07-31 Affymetrix, Inc. Nucleic acid analysis techniques
US5830645A (en) * 1994-12-09 1998-11-03 The Regents Of The University Of California Comparative fluorescence hybridization to nucleic acid arrays
US5545531A (en) 1995-06-07 1996-08-13 Affymax Technologies N.V. Methods for making a device for concurrently processing multiple biological chip assays
US6156502A (en) 1995-12-21 2000-12-05 Beattie; Kenneth Loren Arbitrary sequence oligonucleotide fingerprinting
WO1997029212A1 (en) 1996-02-08 1997-08-14 Affymetrix, Inc. Chip-based speciation and phenotypic characterization of microorganisms
AU4327697A (en) 1996-08-20 1998-03-06 Motorola, Inc. Method and apparatus for detecting predetermined molecular structures in a sample
EP0960214A4 (de) * 1996-12-06 2004-08-04 Urocor Inc Diagnose des Krankheitszustandesan HAnd von mRNA-Profilen
US6235474B1 (en) 1996-12-30 2001-05-22 The Johns Hopkins University Methods and kits for diagnosing and determination of the predisposition for diseases
US6190857B1 (en) * 1997-03-24 2001-02-20 Urocor, Inc. Diagnosis of disease state using MRNA profiles in peripheral leukocytes
NO972006D0 (no) * 1997-04-30 1997-04-30 Forskningsparken I Aas As Ny metode for diagnose av sykdommer
US5994076A (en) 1997-05-21 1999-11-30 Clontech Laboratories, Inc. Methods of assaying differential expression
WO1999006831A2 (en) 1997-07-29 1999-02-11 Dorssers Lambert C J Breast cancer resistance genes, methods for their detection and uses thereof
US6607879B1 (en) * 1998-02-09 2003-08-19 Incyte Corporation Compositions for the detection of blood cell and immunological response gene expression
WO1999044062A1 (en) 1998-02-25 1999-09-02 The United States Of America As Represented By The Secretary Department Of Health And Human Services Cellular arrays for rapid molecular profiling
US6004755A (en) 1998-04-07 1999-12-21 Incyte Pharmaceuticals, Inc. Quantitative microarray hybridizaton assays
CN1313908A (zh) 1998-08-21 2001-09-19 纳克斯科尔公司 使用可交联的固定的核酸的检测法
AU1115200A (en) 1998-10-13 2000-05-01 Clontech Laboratories, Inc. Nucleic acid arrays
US6593084B2 (en) 1998-10-13 2003-07-15 Robert E. Bird Carcinogen assay
EP1131470A4 (de) 1998-10-28 2004-11-10 Vysis Inc Zelluläre arrays sowie verfahren zur detektion und verwendung von markern für genetische störungen
WO2000026412A1 (en) 1998-11-02 2000-05-11 Kenneth Loren Beattie Nucleic acid analysis using sequence-targeted tandem hybridization
US20040265868A1 (en) * 1999-01-06 2004-12-30 Chondrogene Limited Method for the detection of depression related gene transcripts in blood
US20040265869A1 (en) * 1999-01-06 2004-12-30 Chondrogene Limited Method for the detection of type II diabetes related gene transcripts in blood
US20040241726A1 (en) * 1999-01-06 2004-12-02 Chondrogene Limited Method for the detection of allergies related gene transcripts in blood
US20040248169A1 (en) * 1999-01-06 2004-12-09 Chondrogene Limited Method for the detection of obesity related gene transcripts in blood
WO2000040749A2 (en) * 1999-01-06 2000-07-13 Genenews Inc. Method for the detection of gene transcripts in blood and uses thereof
US20050042630A1 (en) * 1999-01-06 2005-02-24 Chondrogene Limited Method for the detection of asthma related gene transcripts in blood
US20040241727A1 (en) * 1999-01-06 2004-12-02 Chondrogene Limited Method for the detection of schizophrenia related gene transcripts in blood
US7473528B2 (en) * 1999-01-06 2009-01-06 Genenews Inc. Method for the detection of Chagas disease related gene transcripts in blood
US20040241728A1 (en) * 1999-01-06 2004-12-02 Chondrogene Limited Method for the detection of lung disease related gene transcripts in blood
US20040248170A1 (en) * 1999-01-06 2004-12-09 Chondrogene Limited Method for the detection of hyperlipidemia related gene transcripts in blood
US20050003394A1 (en) * 1999-01-06 2005-01-06 Chondrogene Limited Method for the detection of rheumatoid arthritis related gene transcripts in blood
US20020169560A1 (en) * 2001-05-12 2002-11-14 X-Mine Analysis mechanism for genetic data

Also Published As

Publication number Publication date
DE69840154D1 (de) 2008-12-04
US20020022222A1 (en) 2002-02-21
HK1026003A1 (en) 2000-12-01
AU7222698A (en) 1998-11-24
DK0979308T3 (da) 2005-04-18
US6720138B2 (en) 2004-04-13
DE69828392D1 (de) 2005-02-03
EP2050825A1 (de) 2009-04-22
DK1323728T3 (da) 2009-03-02
WO1998049342A1 (en) 1998-11-05
HK1057217A1 (en) 2004-03-19
JP2001526534A (ja) 2001-12-18
ATE412003T1 (de) 2008-11-15
EP0979308A1 (de) 2000-02-16
US20040121390A1 (en) 2004-06-24
PT979308E (pt) 2005-03-31
NO972006D0 (no) 1997-04-30
EP1323728A3 (de) 2004-02-04
EP0979308B1 (de) 2004-12-29
DE69828392T2 (de) 2005-12-01
EP1323728A2 (de) 2003-07-02
ES2316693T3 (es) 2009-04-16
NO20040371L (no) 1999-12-14
NO327084B1 (no) 2009-04-20
US20130337446A1 (en) 2013-12-19
US20050227286A1 (en) 2005-10-13
EP1323728B1 (de) 2008-10-22
CY1108716T1 (el) 2014-04-09
PT1323728E (pt) 2009-01-23
ES2230688T3 (es) 2005-05-01
JP4163758B2 (ja) 2008-10-08

Similar Documents

Publication Publication Date Title
DE69828392D1 (de) Verfahren zur Herstellung eines diagnostischen Standard-Gentranskriptionsmusters
WO2000077260A8 (en) Genomic profiling: a rapid method for testing a complex biological sample for the presence of many types of organisms
NZ788335A (en) Determination of base modifications of nucleic acids
US5650277A (en) Method of determining the presence and quantifying the number of di- and trinucleotide repeats
CN110878343B (zh) 一种用于遗传性耳聋致病基因SLC26A4突变快速检测的Cpf1试剂盒及其检测方法
ATE361996T1 (de) Methoden und zusammensetzungen zur vervielfältigung von rna sequenzen
ATE333517T1 (de) Verfahren und sondenset zur erkennung von krebs
WO2001057275A3 (en) Human genome-derived single exon nucleic acid probes useful for analysis of gene expression in human brain
DE69131596D1 (de) Dns-abhängige rns-polymerase-transkripte als reportermoleküle zur signalverstärkung in nukleinsäure-hybridisierungsuntersuchungen
EP1366196A4 (de) Verfahren und zusammensetzungen zur amplifikation von rna
WO2002074911A3 (en) Identification of gene expression alterations underlying the aging process in mammals
CN109852667A (zh) 基于单分子力谱探测核酸末端结构的方法
ATE220427T1 (de) Verfahren zum nachweis von nukleinsäure- zielsequenzen mittels in vitro transkription von einem rna-promoter
TW200502400A (en) Nucleic acid detection
WO2005054516A3 (en) Peptide nucleic acid probes for analysis of certain staphylococcus species
DE50206574D1 (de) Verfahren zur herstellung eines arrays zur detektion von komponenten aus einer biologischen probe
EP4265721A1 (de) Verfahren zur beurteilung der adapterligationseffizienz in einer sequenz einer dna-probe
WO2006125012A3 (en) Compositions, methods and kits for real-time nucleic acid analysis in live cells
WO2021243170A3 (en) Method and system for rna isolation from self-collected and small volume samples
JPWO2005118791A1 (ja) 微量試料を用いる網羅的遺伝子発現プロフィール解析法
DE69535023D1 (de) Ein diagnose-verfahren und ein testsatz für die bestimmung des kell blutgruppln-nenotyps
ATE378427T1 (de) Verfahren zur bestimmung einer unbekannten pns seqenz und seine verwendungen
WO1999024607A3 (en) DETECTION AND TYPING OF THE iceA GENE OF $i(HELICOBACTER PYLORI)
CN109082424A (zh) 一种标记Marker及其制备方法
WO2002099117A3 (en) Nucleic acid regulatory sequences and uses therefor

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification

Ref document number: 0979308

Country of ref document: EP