ATE286382T1 - Polyethylenglycol-matrixpellets für fettige, ölige oder klebrige arzneistoffe - Google Patents

Polyethylenglycol-matrixpellets für fettige, ölige oder klebrige arzneistoffe

Info

Publication number
ATE286382T1
ATE286382T1 AT98957269T AT98957269T ATE286382T1 AT E286382 T1 ATE286382 T1 AT E286382T1 AT 98957269 T AT98957269 T AT 98957269T AT 98957269 T AT98957269 T AT 98957269T AT E286382 T1 ATE286382 T1 AT E286382T1
Authority
AT
Austria
Prior art keywords
oily
fatty
polyethylene glycol
medicinal substances
matrix pellets
Prior art date
Application number
AT98957269T
Other languages
English (en)
Inventor
Christer Karlsson
Per Johan Lundberg
Adam Rosinski
Malin Soederbom
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Application granted granted Critical
Publication of ATE286382T1 publication Critical patent/ATE286382T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/662—Phosphorus acids or esters thereof having P—C bonds, e.g. foscarnet, trichlorfon
    • A61K31/663—Compounds having two or more phosphorus acid groups or esters thereof, e.g. clodronic acid, pamidronic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4422—1,4-Dihydropyridines, e.g. nifedipine, nicardipine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT98957269T 1997-11-28 1998-11-18 Polyethylenglycol-matrixpellets für fettige, ölige oder klebrige arzneistoffe ATE286382T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE9704401A SE9704401D0 (sv) 1997-11-28 1997-11-28 Matrix pellets for greasy, oily or sticky drug substances
PCT/SE1998/002090 WO1999027913A1 (en) 1997-11-28 1998-11-18 Polyethylene glycol matrix pellets for greasy, oily or sticky drug substances

Publications (1)

Publication Number Publication Date
ATE286382T1 true ATE286382T1 (de) 2005-01-15

Family

ID=20409178

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98957269T ATE286382T1 (de) 1997-11-28 1998-11-18 Polyethylenglycol-matrixpellets für fettige, ölige oder klebrige arzneistoffe

Country Status (23)

Country Link
US (2) US6555138B1 (de)
EP (1) EP1032371B1 (de)
JP (1) JP2001524514A (de)
KR (1) KR20010032558A (de)
CN (1) CN1280493A (de)
AR (1) AR016684A1 (de)
AT (1) ATE286382T1 (de)
AU (1) AU746324B2 (de)
BR (1) BR9814756A (de)
CA (1) CA2311930A1 (de)
DE (1) DE69828527T2 (de)
HU (1) HUP0004405A3 (de)
ID (1) ID24185A (de)
IL (1) IL136144A0 (de)
NO (1) NO20002720L (de)
NZ (1) NZ504354A (de)
PL (1) PL340926A1 (de)
RU (1) RU2216316C2 (de)
SE (1) SE9704401D0 (de)
SK (1) SK6592000A3 (de)
TW (1) TW570813B (de)
WO (1) WO1999027913A1 (de)
ZA (1) ZA9810465B (de)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6515009B1 (en) 1991-09-27 2003-02-04 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
US5811447A (en) 1993-01-28 1998-09-22 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
SE9704401D0 (sv) * 1997-11-28 1997-11-28 Astra Ab Matrix pellets for greasy, oily or sticky drug substances
IT1319202B1 (it) 2000-10-12 2003-09-26 Nicox Sa Farmaci per le malattie a base infiammatoria.
US6462021B1 (en) 2000-11-06 2002-10-08 Astrazeneca Ab Use of low molecular weight thrombin inhibitor
AR035216A1 (es) 2000-12-01 2004-05-05 Astrazeneca Ab Derivados de acido mandelico ,derivados farmaceuticamente aceptables, uso de estos derivados para la fabricacion de medicamentos, metodos de tratamiento ,procesos para la preparacion de estos derivados, y compuestos intermediarios
US6613083B2 (en) 2001-05-02 2003-09-02 Eckhard Alt Stent device and method
SE0201658D0 (sv) * 2002-05-31 2002-05-31 Astrazeneca Ab Immediate release pharmaceutical formulation
JP3887588B2 (ja) * 2002-08-30 2007-02-28 株式会社リガク Ｘ線回折による応力測定法
US8986737B2 (en) * 2002-09-05 2015-03-24 Wm. Marsh Rice University Antibiotic microspheres for treatment and prevention of osteomyelitis and enhancement of bone regrowth
CN100513398C (zh) 2002-12-03 2009-07-15 Axys药物公司 作为因子viia抑制剂的2-(2-羟基联苯-3-基)-1h-苯并咪唑-5-甲脒衍生物
US20070059358A1 (en) * 2003-07-02 2007-03-15 Tianjin Tasly Pharmaceutical Co., Ltd., China Matrix adjuvants and the drop pills prepared with them
EP2043613A1 (de) * 2006-07-14 2009-04-08 Fmc Corporation Feste form
EP2114455A4 (de) * 2006-12-20 2010-03-17 Mylan Pharmaceuticals Ulc Pharmazeutische zusammensetzung mit einem heissschmelzgranuliertem gleitmittel
AU2014201170B2 (en) * 2006-12-20 2015-09-24 Mylan Pharmaceuticals Ulc Pharmaceutical composition comprising a hot-melt granulated lubricant
US20080311162A1 (en) * 2007-05-16 2008-12-18 Olivia Darmuzey Solid form
CN110279885B (zh) 2013-09-19 2022-07-26 泰尔茂株式会社 聚合物颗粒
BR112016005768B1 (pt) 2013-09-19 2021-09-21 Microvention, Inc Películas de polímero
BR112016010067B1 (pt) 2013-11-08 2023-01-10 Terumo Corporation Partículas de polímero e métodos de preparação
CN104133014B (zh) * 2014-07-16 2015-09-16 广州法尔麦兰药物技术有限公司 一种考察布洛伪麻缓释制剂释放度的方法
US9907880B2 (en) 2015-03-26 2018-03-06 Microvention, Inc. Particles
KR102310696B1 (ko) 2016-09-28 2021-10-12 테루모 가부시키가이샤 색전 조성물

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE557670C (de) 1932-08-26 Friedrich Rittershausen Abtast- bzw. Bildzusammensetzvorrichtung
DE454386C (de) 1924-05-27 1928-01-06 Chemische Produkte Vormals H S Verfahren zur Herstellung pharmazeutischer und diaetetischer Praeparate in kugelaehnlicher Form
US2699054A (en) 1953-10-09 1955-01-11 Lloyd H Conover Tetracycline
DE2251197C3 (de) 1972-10-19 1980-05-08 Hoechst Ag, 6000 Frankfurt Verfahren zur Herstellung von hxxochdosierten Tabletten von Tetracyclin- Derivaten
GB8613689D0 (en) * 1986-06-05 1986-07-09 Euro Celtique Sa Pharmaceutical composition
DE3636123A1 (de) * 1986-10-23 1988-05-05 Rentschler Arzneimittel Arzneizubereitungen zur oralen verabreichung, die als einzeldosis 10 bis 240 mg dihydropyridin enthalten
US5051261A (en) * 1987-11-24 1991-09-24 Fmc Corporation Method for preparing a solid sustained release form of a functionally active composition
DE3871343D1 (de) * 1987-11-25 1992-06-25 American Cyanamid Co System fuer die verzoegerte (kontrollierte) freisetzung von substituierten dihydropyridin-calciumantagonisten.
US5876754A (en) * 1992-01-17 1999-03-02 Alfatec-Pharma Gmbh Solid bodies containing active substances and a structure consisting of hydrophilic macromolecules, plus a method of producing such bodies
ES2133633T3 (es) * 1992-01-17 1999-09-16 Alfatec Pharma Gmbh Procedimiento para la produccion de polvos, granulados o peletes que contienen una sustancia activa, con una estructura a base de macromoleculas hidrofilas, y su utilizacion.
EP0557670B1 (de) * 1992-02-25 1999-05-06 Spirig Ag Pharmazeutische Präparate Minocyclin enthaltende Pellets
US5431920A (en) * 1993-09-21 1995-07-11 Merck Frosst, Canada, Inc. Enteric coated oral compositions containing bisphosphonic acid antihypercalcemic agents
SE9704401D0 (sv) * 1997-11-28 1997-11-28 Astra Ab Matrix pellets for greasy, oily or sticky drug substances

Also Published As

Publication number Publication date
AU746324B2 (en) 2002-04-18
RU2216316C2 (ru) 2003-11-20
CN1280493A (zh) 2001-01-17
DE69828527T2 (de) 2005-12-29
NO20002720L (no) 2000-07-28
HUP0004405A3 (en) 2004-03-29
AU1356499A (en) 1999-06-16
WO1999027913A1 (en) 1999-06-10
IL136144A0 (en) 2001-05-20
NZ504354A (en) 2001-12-21
KR20010032558A (ko) 2001-04-25
HUP0004405A2 (hu) 2001-08-28
SK6592000A3 (en) 2001-01-18
NO20002720D0 (no) 2000-05-26
BR9814756A (pt) 2000-10-03
SE9704401D0 (sv) 1997-11-28
DE69828527D1 (de) 2005-02-10
ZA9810465B (en) 1999-05-21
EP1032371A1 (de) 2000-09-06
AR016684A1 (es) 2001-07-25
TW570813B (en) 2004-01-11
ID24185A (id) 2000-07-13
PL340926A1 (en) 2001-03-12
US20030175352A1 (en) 2003-09-18
CA2311930A1 (en) 1999-06-10
EP1032371B1 (de) 2005-01-05
JP2001524514A (ja) 2001-12-04
US6555138B1 (en) 2003-04-29

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Legal Events

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RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties