ATE286895T1 - Sulfonyl-pyrrolidinderivate geeignet für die behandlung von neurologischen krankheiten - Google Patents

Sulfonyl-pyrrolidinderivate geeignet für die behandlung von neurologischen krankheiten

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Publication number
ATE286895T1
ATE286895T1 AT01960365T AT01960365T ATE286895T1 AT E286895 T1 ATE286895 T1 AT E286895T1 AT 01960365 T AT01960365 T AT 01960365T AT 01960365 T AT01960365 T AT 01960365T AT E286895 T1 ATE286895 T1 AT E286895T1
Authority
AT
Austria
Prior art keywords
sulfonyl
treatment
neurological diseases
pyrrolidine derivatives
derivatives suitable
Prior art date
Application number
AT01960365T
Other languages
English (en)
Inventor
Vincent Mutel
Juergen Wichmann
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Application granted granted Critical
Publication of ATE286895T1 publication Critical patent/ATE286895T1/de

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
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    • A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/46—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with hetero atoms directly attached to the ring nitrogen atom
    • C07D207/48—Sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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  • Pharmacology & Pharmacy (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Diabetes (AREA)
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  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Addiction (AREA)
  • Pain & Pain Management (AREA)
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  • Urology & Nephrology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
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  • Hospice & Palliative Care (AREA)
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AT01960365T 2000-06-30 2001-06-22 Sulfonyl-pyrrolidinderivate geeignet für die behandlung von neurologischen krankheiten ATE286895T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP00113894 2000-06-30
PCT/EP2001/007135 WO2002002554A1 (en) 2000-06-30 2001-06-22 Sulfonyl-pyrrolidine derivatives useful for the treatment of neurological disorders

Publications (1)

Publication Number Publication Date
ATE286895T1 true ATE286895T1 (de) 2005-01-15

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AT01960365T ATE286895T1 (de) 2000-06-30 2001-06-22 Sulfonyl-pyrrolidinderivate geeignet für die behandlung von neurologischen krankheiten

Country Status (34)

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US (2) US6589978B2 (de)
EP (1) EP1299383B1 (de)
JP (1) JP3994051B2 (de)
KR (1) KR100529423B1 (de)
CN (1) CN1178936C (de)
AR (1) AR029288A1 (de)
AT (1) ATE286895T1 (de)
AU (2) AU2001281877B2 (de)
BR (1) BR0112093A (de)
CA (1) CA2413243A1 (de)
CZ (1) CZ2003280A3 (de)
DE (1) DE60108394T2 (de)
DK (1) DK1299383T3 (de)
EC (1) ECSP024403A (de)
ES (1) ES2234869T3 (de)
HR (1) HRP20021023B1 (de)
HU (1) HUP0301167A3 (de)
IL (2) IL153425A0 (de)
JO (1) JO2384B1 (de)
MA (1) MA26923A1 (de)
MX (1) MXPA02012270A (de)
MY (1) MY126903A (de)
NO (1) NO324218B1 (de)
NZ (1) NZ523025A (de)
PE (1) PE20020103A1 (de)
PL (1) PL360396A1 (de)
PT (1) PT1299383E (de)
RU (1) RU2272026C2 (de)
SI (1) SI1299383T1 (de)
TW (1) TWI265928B (de)
UY (1) UY26812A1 (de)
WO (1) WO2002002554A1 (de)
YU (1) YU99702A (de)
ZA (1) ZA200209966B (de)

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EP2021000A2 (de) 2006-05-09 2009-02-11 Braincells, Inc. Neurogenese mittels angiotensin-modulation
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BRPI0714764A2 (pt) * 2006-09-29 2014-12-30 Gruenenthal Gmbh Derivados substituídos de sulfonamida
US8933105B2 (en) 2007-02-28 2015-01-13 Takeda Pharmaceutical Company Limited Pyrrole compounds
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HRP20021023B1 (en) 2006-08-31
IL153425A (en) 2007-08-19
NO324218B1 (no) 2007-09-10
US20030212066A1 (en) 2003-11-13
KR100529423B1 (ko) 2005-11-17
US6589978B2 (en) 2003-07-08
US6995182B2 (en) 2006-02-07
NO20026263D0 (no) 2002-12-27
ZA200209966B (en) 2004-03-09
DE60108394T2 (de) 2006-03-02
HK1058358A1 (en) 2004-05-14
CA2413243A1 (en) 2002-01-10
HUP0301167A2 (hu) 2003-08-28
HRP20021023A2 (en) 2004-08-31
HUP0301167A3 (en) 2009-12-28
JP3994051B2 (ja) 2007-10-17
MY126903A (en) 2006-10-31
CZ2003280A3 (cs) 2003-12-17
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CN1178936C (zh) 2004-12-08
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NO20026263L (no) 2002-12-27
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RU2272026C2 (ru) 2006-03-20
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MA26923A1 (fr) 2004-12-20
PT1299383E (pt) 2005-05-31
JO2384B1 (en) 2007-06-17
EP1299383A1 (de) 2003-04-09
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US20020019424A1 (en) 2002-02-14
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