ATE287661T1 - Augenanalytfühler - Google Patents

Augenanalytfühler

Info

Publication number
ATE287661T1
ATE287661T1 AT00960520T AT00960520T ATE287661T1 AT E287661 T1 ATE287661 T1 AT E287661T1 AT 00960520 T AT00960520 T AT 00960520T AT 00960520 T AT00960520 T AT 00960520T AT E287661 T1 ATE287661 T1 AT E287661T1
Authority
AT
Austria
Prior art keywords
analyte
fluid
moiety
concentration
analyst
Prior art date
Application number
AT00960520T
Other languages
English (en)
Inventor
Wayne Front March
Original Assignee
Novartis Pharma Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Pharma Gmbh filed Critical Novartis Pharma Gmbh
Application granted granted Critical
Publication of ATE287661T1 publication Critical patent/ATE287661T1/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/145Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A61B5/1455Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/145Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A61B5/14532Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue for measuring glucose, e.g. by tissue impedance measurement
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/41Detecting, measuring or recording for evaluating the immune or lymphatic systems
    • A61B5/411Detecting or monitoring allergy or intolerance reactions to an allergenic agent or substance
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/0002Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00Nanotechnology
    • Y10S977/902Specified use of nanostructure
    • Y10S977/904Specified use of nanostructure for medical, immunological, body treatment, or diagnosis
    • Y10S977/905Specially adapted for travel through blood circulatory system

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biophysics (AREA)
  • Public Health (AREA)
  • Pathology (AREA)
  • Optics & Photonics (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Immunology (AREA)
  • Vascular Medicine (AREA)
  • Emergency Medicine (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Prostheses (AREA)
  • Eye Examination Apparatus (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AT00960520T 1999-08-26 2000-08-24 Augenanalytfühler ATE287661T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US15079299P 1999-08-26 1999-08-26
US18598000P 2000-03-01 2000-03-01
PCT/EP2000/008285 WO2001013783A1 (en) 1999-08-26 2000-08-24 Ocular analyte sensor

Publications (1)

Publication Number Publication Date
ATE287661T1 true ATE287661T1 (de) 2005-02-15

Family

ID=26848047

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00960520T ATE287661T1 (de) 1999-08-26 2000-08-24 Augenanalytfühler

Country Status (15)

Country Link
US (2) US6681127B2 (de)
EP (1) EP1206213B1 (de)
JP (1) JP4421160B2 (de)
KR (1) KR100675706B1 (de)
CN (1) CN1196436C (de)
AT (1) ATE287661T1 (de)
AU (1) AU767995B2 (de)
BR (1) BR0013609B1 (de)
CA (1) CA2381520C (de)
DE (1) DE60017755T2 (de)
HK (1) HK1048244B (de)
HU (1) HU226183B1 (de)
MX (1) MXPA02002029A (de)
NO (1) NO20020851L (de)
WO (1) WO2001013783A1 (de)

Families Citing this family (82)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6544193B2 (en) * 1996-09-04 2003-04-08 Marcio Marc Abreu Noninvasive measurement of chemical substances
US6120460A (en) * 1996-09-04 2000-09-19 Abreu; Marcio Marc Method and apparatus for signal acquisition, processing and transmission for evaluation of bodily functions
CA2381520C (en) * 1999-08-26 2009-05-26 Novartis Ag Ocular analyte sensor
US7998412B2 (en) 2000-01-07 2011-08-16 Smart Holograms Limited Ophthalmic device comprising a holographic sensor
GB0016841D0 (en) 2000-07-07 2000-08-30 Stanley Christopher J Optical device for measurement of analytes in tears
DE60223668T2 (de) 2001-04-27 2008-10-30 Eyesense Ag Kit zur messung von blutzuckerkonzentrationen
US6827966B2 (en) * 2001-05-30 2004-12-07 Novartis Ag Diffusion-controllable coatings on medical device
US6650915B2 (en) * 2001-09-13 2003-11-18 Fovioptics, Inc. Non-invasive measurement of blood analytes using photodynamics
US20050010091A1 (en) * 2003-06-10 2005-01-13 Woods Joe W. Non-invasive measurement of blood glucose using retinal imaging
US20030153026A1 (en) * 2002-01-04 2003-08-14 Javier Alarcon Entrapped binding protein as biosensors
US20050239155A1 (en) * 2002-01-04 2005-10-27 Javier Alarcon Entrapped binding protein as biosensors
US6939298B2 (en) * 2002-02-28 2005-09-06 Gmp Vision Solutions, Inc Device and method for monitoring aqueous flow within the eye
US8328420B2 (en) 2003-04-22 2012-12-11 Marcio Marc Abreu Apparatus and method for measuring biologic parameters
KR101124852B1 (ko) * 2002-04-22 2012-03-28 마시오 마크 아우렐리오 마틴스 애브리우 생물학적 파라미터 측정 장치 및 방법
US8849379B2 (en) * 2002-04-22 2014-09-30 Geelux Holdings, Ltd. Apparatus and method for measuring biologic parameters
US9848815B2 (en) 2002-04-22 2017-12-26 Geelux Holdings, Ltd. Apparatus and method for measuring biologic parameters
US6895264B2 (en) * 2002-08-26 2005-05-17 Fovioptics Inc. Non-invasive psychophysical measurement of glucose using photodynamics
US7244394B2 (en) 2002-10-03 2007-07-17 Novartis Ag Methods and kits for assays of analytes of interest in tears
US20050038329A1 (en) * 2002-11-20 2005-02-17 Morris Carol Ann Methods and kits for assays of rapid screening of diabetes
WO2004064629A1 (en) * 2003-01-21 2004-08-05 Ehrfeld Miktotechnik Ag Sensor system for detecting analytes in tear fluid
US7534207B2 (en) * 2003-02-07 2009-05-19 Alfred E. Mann Institute For Biomedical Engineering At The University Of Southern California Implantable device with sensors for differential monitoring of internal condition
DE602004022638D1 (de) 2003-02-28 2009-10-01 Eyesense Ag Biomoleküle enthaltende copolymere
US20040181172A1 (en) * 2003-03-12 2004-09-16 Carney Fiona Patricia Devices for collecting analytes of interest in tears
EP1644330B1 (de) * 2003-06-27 2011-08-17 The University Of Maryland Heterocyclische verbindungen mit quaternärem stickstoff zum nachweis von wässrigen monosacchariden in physiologischen flüssigkeiten
WO2005015184A1 (en) 2003-07-30 2005-02-17 Novartis Ag Reflection hologram sensor in contact lens
EP1654543B1 (de) 2003-08-07 2010-07-07 EyeSense AG Ophthalmischer sensor
US7214190B1 (en) 2003-09-09 2007-05-08 Kitchener Clark Wilson Apparatus and method for noninvasive monitoring of analytes in body fluids
CA2540076A1 (en) * 2003-09-25 2005-04-07 Smart Holograms Limited Ophthalmic device comprising a holographic sensor
US10227063B2 (en) 2004-02-26 2019-03-12 Geelux Holdings, Ltd. Method and apparatus for biological evaluation
US20060258920A1 (en) * 2004-04-14 2006-11-16 Oculir, Inc. Non-Invasive Analyte Measurement Glasses and Method of Use
AU2005251479A1 (en) * 2004-06-14 2005-12-22 Eyesense Ag Combined apparatus for measuring the blood glucose level from an ocular fluid
JP4455216B2 (ja) 2004-08-06 2010-04-21 キヤノン株式会社 検出装置
CA2543964A1 (en) * 2005-04-19 2006-10-19 Anton Sabeta Ophthalmic lens characterization
CA2944254A1 (en) 2005-10-24 2007-05-03 Marcio Marc Abreu Apparatus and method for measuring biologic parameters
US8515518B2 (en) * 2005-12-28 2013-08-20 Abbott Diabetes Care Inc. Analyte monitoring
JP4615470B2 (ja) 2006-03-29 2011-01-19 卓郎 簑和田 大脳の認知力を用いた疾患治療・予防の方法および医薬
DK1882446T3 (da) 2006-07-24 2009-01-12 Eyesense Ag Anordning til måling af en analyt i en öjenvæske
US8090426B2 (en) 2006-10-27 2012-01-03 Felder Robin A Microelectronic biosensor plug
DE102007003341B4 (de) * 2007-01-17 2018-01-04 Eyesense Ag Okularsensor und Messsystem zum Nachweis eines Analyten in einer Augenflüssigkeit
US8446341B2 (en) * 2007-03-07 2013-05-21 University Of Washington Contact lens with integrated light-emitting component
KR20100016598A (ko) * 2007-05-10 2010-02-12 보르그워너 인코퍼레이티드 냉각 팬용 상승작용적 블레이드와 허브 구조
DE102007024642A1 (de) 2007-05-24 2008-11-27 Eyesense Ag Hydrogel-Implantat für Sensorik von Metaboliten am Auge
US7802883B2 (en) 2007-12-20 2010-09-28 Johnson & Johnson Vision Care, Inc. Cosmetic contact lenses having a sparkle effect
DE502008003439D1 (de) 2008-10-02 2011-06-16 Eyesense Ag Implantationsvorrichtung für Metabolitsensoren
ES2530450T3 (es) 2008-10-02 2015-03-03 Eyesense Ag Elemento sensor implantable
CA2683467C (en) * 2008-10-24 2016-01-26 Jin Zhang Contact lens integrated with a biosensor for detection of glucose and other components in tears
US20100168851A1 (en) * 2008-12-30 2010-07-01 David Paul Vanderbilt Surface Modified Biomedical Devices
EP2410908A1 (de) * 2009-03-26 2012-02-01 The Arizona Board of Regents for and on behalf of Arizona State University Integrierte vorrichtung für oberflächenkontakt-probennahme und -extraktion sowie elektrochemische messungen
CN102596013A (zh) * 2009-09-18 2012-07-18 阿克伦大学 用于无创实时检测血糖水平的光学装置和方法
US8741591B2 (en) 2009-10-09 2014-06-03 The Research Foundation For The State University Of New York pH-insensitive glucose indicator protein
WO2012080218A1 (de) 2010-12-17 2012-06-21 Eyesense Ag Kompetitiver biosensor mit erhöhter sensitivität
CN103370623B (zh) 2010-12-17 2016-05-04 视觉股份公司 水凝胶在具有提高的灵敏度的生物传感器中的用途
EP2508935A1 (de) 2011-04-08 2012-10-10 Nxp B.V. Flexibler Augeneinsatz und Glukosemesssystem
WO2013019722A1 (en) * 2011-08-01 2013-02-07 Massachusetts Institute Of Technology Photoluminescent nanostructure-based sensors
EP3659495B1 (de) 2011-09-13 2022-12-14 Dose Medical Corporation Intraokularer physiologischer sensor
US8874182B2 (en) 2013-01-15 2014-10-28 Google Inc. Encapsulated electronics
US9730638B2 (en) 2013-03-13 2017-08-15 Glaukos Corporation Intraocular physiological sensor
US9289623B2 (en) * 2013-03-15 2016-03-22 Johnson & Johnson Vision Care, Inc. Method and device for monitoring and treatment of seasonal affective disorder
US20140350373A1 (en) * 2013-05-21 2014-11-27 Johnson & Johnson Vision Care, Inc. Ophthalmic lens with a passive event-based coloration system
US9084561B2 (en) * 2013-06-17 2015-07-21 Google Inc. Symmetrically arranged sensor electrodes in an ophthalmic electrochemical sensor
US9044075B2 (en) * 2013-06-24 2015-06-02 Google Inc. Container
ES2531189B2 (es) * 2013-08-05 2015-12-18 Universidad De Alicante Procedimiento de cuantificación de la opacidad ocular de una lente intraocular
EP3055659A4 (de) 2013-10-11 2017-12-06 Marcio Marc Abreu Verfahren und vorrichtung für biologische evaluierung
US9701458B2 (en) 2013-12-19 2017-07-11 Verily Life Sciences Llc Packaging for an active contact lens
US9576168B2 (en) * 2013-12-30 2017-02-21 Verily Life Sciences Llc Conditional retrieval
CA2936229A1 (en) 2014-01-10 2015-07-16 Marcio Marc Abreu Device for measuring the infrared output of the abreu brain thermal tunnel
WO2015106180A1 (en) 2014-01-10 2015-07-16 Marcio Marc Abreu Devices to monitor and provide treatment at an abreu brain tunnel
JP2017503604A (ja) 2014-01-22 2017-02-02 マーシオ マーク アブリュー Abreu脳熱トンネルでの治療を提供するように構成されたデバイス
JP2016008818A (ja) * 2014-06-20 2016-01-18 ソニー株式会社 検出装置および方法、並びにプログラム
KR101638106B1 (ko) * 2014-07-02 2016-07-11 충남대학교 산학협력단 형광 가교 폴리(n-아이소프로필 아크릴아마이드) 마이크로젤, 이의 제조방법 및 이를 포함하는 센서
EP2979662A1 (de) * 2014-08-01 2016-02-03 Akkolens International B.V. Intraokularlinse mit einem stromgenerator und zusätzlichen funktionssystemen
WO2016054079A1 (en) 2014-09-29 2016-04-07 Zyomed Corp. Systems and methods for blood glucose and other analyte detection and measurement using collision computing
JP2018512915A (ja) 2015-03-10 2018-05-24 マーシオ マーク アブリュー Abtt終端の温度を測定するためのデバイス、装置、システム、及び方法
WO2016178151A1 (en) * 2015-05-04 2016-11-10 Ecole Polytechnique Federale De Lausanne (Epfl) Ophthalmic contact lens with a compressible affinity matrix
JP2017023328A (ja) * 2015-07-21 2017-02-02 富士ゼロックス株式会社 光学活性物質の濃度算出システム及びプログラム
CH711991B1 (de) * 2015-12-22 2023-11-30 Dosilab AG Dosimetervorrichtung.
US9554738B1 (en) 2016-03-30 2017-01-31 Zyomed Corp. Spectroscopic tomography systems and methods for noninvasive detection and measurement of analytes using collision computing
AU2017298463B2 (en) * 2016-07-20 2022-09-01 University Of Maryland, Baltimore Silicone hydrogel based fluorescent assay and contact lens
WO2018187693A1 (en) 2017-04-06 2018-10-11 TearDX LLC Ocular devices and methods for the employment thereof
KR102480725B1 (ko) * 2017-12-28 2022-12-22 트랜지션즈 옵티칼 리미티드 콘택트렌즈의 광학 특성을 측정하기 위한 방법 및 시스템
JP7033673B2 (ja) 2018-03-13 2022-03-10 株式会社メニコン 判定システム、演算装置、判定方法、およびプログラム
WO2019175662A1 (en) * 2018-03-13 2019-09-19 Menicon Co. Ltd. Glucose sensing contact lens

Family Cites Families (43)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3769961A (en) 1972-07-20 1973-11-06 I Fatt Conjunctival device
US4168112A (en) * 1978-01-05 1979-09-18 Polymer Technology Corporation Contact lens with a hydrophilic, polyelectrolyte complex coating and method for forming same
US4344438A (en) 1978-08-02 1982-08-17 The United States Of America As Represented By The Department Of Health, Education And Welfare Optical sensor of plasma constituents
US4298801A (en) * 1980-01-17 1981-11-03 General Electric Company L-U Arm handle assembly
US4330299A (en) 1981-03-09 1982-05-18 Evreka, Inc. Article and method for measuring glucose level in body fluids
DE3313047A1 (de) 1983-04-12 1984-10-18 Max Planck Gesellschaft zur Förderung der Wissenschaften e.V., 3400 Göttingen Anordnung zur messung von diffundierenden partikeln
EP0236023A3 (de) 1986-03-03 1988-09-07 Seymour Norman Blackman Nicht-eindringendes Verfahren zum Messen des Blut-Glucose-Spiegels
US5263992A (en) 1986-10-17 1993-11-23 Bio-Metric Systems, Inc. Biocompatible device with covalently bonded biocompatible agent
SU1534406A1 (ru) 1987-11-25 1990-01-07 Военно-Медицинская Краснознаменная Академия Им.С.М.Кирова Способ диагностики скрытой формы сахарного диабета
US5342789A (en) 1989-12-14 1994-08-30 Sensor Technologies, Inc. Method and device for detecting and quantifying glucose in body fluids
US6040194A (en) 1989-12-14 2000-03-21 Sensor Technologies, Inc. Methods and device for detecting and quantifying substances in body fluids
US5222495A (en) 1990-02-02 1993-06-29 Angiomedics Ii, Inc. Non-invasive blood analysis by near infrared absorption measurements using two closely spaced wavelengths
GB9022304D0 (en) 1990-10-15 1990-11-28 Ares Serono Res & Dev Ltd Assay technique
US5435307A (en) * 1991-03-29 1995-07-25 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Surface fluorescent monitor
US5203328A (en) * 1991-07-17 1993-04-20 Georgia Tech Research Corporation Apparatus and methods for quantitatively measuring molecular changes in the ocular lens
US5246867A (en) 1992-01-17 1993-09-21 University Of Maryland At Baltimore Determination and quantification of saccharides by luminescence lifetimes and energy transfer
DE4208645A1 (de) 1992-03-18 1993-09-23 Bayer Ag Optischer festphasenbiosensor auf basis fluoreszenzfarbstoffmarkierter polyionischer schichten
US5433197A (en) 1992-09-04 1995-07-18 Stark; Edward W. Non-invasive glucose measurement method and apparatus
US6256522B1 (en) * 1992-11-23 2001-07-03 University Of Pittsburgh Of The Commonwealth System Of Higher Education Sensors for continuous monitoring of biochemicals and related method
US5341805A (en) 1993-04-06 1994-08-30 Cedars-Sinai Medical Center Glucose fluorescence monitor and method
US5383452A (en) 1993-07-01 1995-01-24 Buchert; Janusz Method, apparatus and procedure for non-invasive monitoring blood glucose by measuring the polarization ratio of blood luminescence
US5352411A (en) 1993-08-13 1994-10-04 Khuri Raja N Device for determination of tear constituents
GB2284809B (en) 1993-11-07 1998-04-29 Japan Res Dev Corp A fluorescent phenylboronic acid suitable for use in the detection of saccharides
CA2235738C (en) 1995-11-22 2005-07-26 Minimed, Inc. Detection of biological molecules using chemical amplification and optical sensors
JP3599878B2 (ja) 1996-03-01 2004-12-08 テルモ株式会社 血糖計
US6120460A (en) 1996-09-04 2000-09-19 Abreu; Marcio Marc Method and apparatus for signal acquisition, processing and transmission for evaluation of bodily functions
US5830139A (en) 1996-09-04 1998-11-03 Abreu; Marcio M. Tonometer system for measuring intraocular pressure by applanation and/or indentation
US5898004A (en) 1996-11-06 1999-04-27 University Of Pittsburgh Of The Commonwealth System Of Higher Education Polymerized crystalline colloidal array sensors
US5854078A (en) 1996-11-06 1998-12-29 University Of Pittsburgh Polymerized crystalline colloidal array sensor methods
AU5446098A (en) 1996-11-21 1998-06-10 Lawrence Livermore National Laboratory Detection of biological molecules using boronate-based chemical amplification and optical sensors
US6197928B1 (en) 1997-03-14 2001-03-06 The Regents Of The University Of California Fluorescent protein sensors for detection of analytes
US6540895B1 (en) * 1997-09-23 2003-04-01 California Institute Of Technology Microfabricated cell sorter for chemical and biological materials
JP3543923B2 (ja) 1997-12-25 2004-07-21 富士写真フイルム株式会社 グルコース濃度測定装置
EP1069857A2 (de) * 1998-04-06 2001-01-24 The General Hospital Corporation Nichtinvasive überwachung des gewebeglukosespiegels
AU759888B2 (en) 1998-07-17 2003-05-01 University Of Maryland At Baltimore Engineered proteins for analyte sensing
AU5565299A (en) 1998-08-17 2000-03-06 California Institute Of Technology Devices and methods for analysis of non-ionic solutes
WO2000016099A1 (en) 1998-09-11 2000-03-23 Sensor Technologies, Inc. Recombinant reduced valency carbohydrate binding ligands
WO2000013580A1 (en) * 1998-09-11 2000-03-16 Amira Medical Device for determination of an analyte in a body fluid intergrated with an insulin pump
WO2000064492A1 (en) 1999-04-27 2000-11-02 University Of Pittsburgh Of The Commonwealth System Of Higher Education Apparatus for optically monitoring concentration of a bioanalyte in blood and related methods
CA2381520C (en) * 1999-08-26 2009-05-26 Novartis Ag Ocular analyte sensor
US6366793B1 (en) * 1999-09-10 2002-04-02 Beckman Coulter, Inc. Minimally invasive methods for measuring analtes in vivo
WO2001018237A1 (en) 1999-09-10 2001-03-15 University Of Maryland, Baltimore Inactive enzymes as non-consuming sensors
GB0016841D0 (en) 2000-07-07 2000-08-30 Stanley Christopher J Optical device for measurement of analytes in tears

Also Published As

Publication number Publication date
BR0013609A (pt) 2002-05-21
HUP0202889A2 (en) 2003-01-28
US20010034500A1 (en) 2001-10-25
US6850786B2 (en) 2005-02-01
NO20020851D0 (no) 2002-02-21
HU226183B1 (en) 2008-06-30
CA2381520A1 (en) 2001-03-01
WO2001013783A1 (en) 2001-03-01
DE60017755D1 (de) 2005-03-03
EP1206213A1 (de) 2002-05-22
HK1048244A1 (en) 2003-03-28
US6681127B2 (en) 2004-01-20
MXPA02002029A (es) 2002-08-20
AU767995B2 (en) 2003-11-27
HK1048244B (zh) 2005-07-29
KR20020026599A (ko) 2002-04-10
DE60017755T2 (de) 2005-06-30
CA2381520C (en) 2009-05-26
NO20020851L (no) 2002-02-21
CN1196436C (zh) 2005-04-13
CN1371256A (zh) 2002-09-25
EP1206213B1 (de) 2005-01-26
JP2003507717A (ja) 2003-02-25
JP4421160B2 (ja) 2010-02-24
AU7279600A (en) 2001-03-19
BR0013609B1 (pt) 2009-01-13
KR100675706B1 (ko) 2007-02-01
US20040059207A1 (en) 2004-03-25

Similar Documents

Publication Publication Date Title
ATE287661T1 (de) Augenanalytfühler
DE602004030474D1 (de) Erfahren dafür
GB2409033B (en) Extended focal region measuring apparatus and method
Vashist Non-invasive glucose monitoring technology in diabetes management: A review
Sebag et al. Raman spectroscopy of human vitreous in proliferative diabetic retinopathy.
Ascaso et al. Noninvasive continuous monitoring of tear glucose using glucose-sensing contact lenses
WO2003009745A3 (en) Instruments and methods for examining and quantifying cataracts
US10028659B2 (en) Aptamer-based sensors, implantable devices and detection system
WO2003101277A3 (en) Noninvasive detection of a physiologic parameter within a body tissue of a patient
WO2004062480A2 (en) Implantable devices and methods for measuring intraocular, subconjunctival or subdermal pressure and/or analyte concentration
WO2002003855A1 (en) Optical device for measurement of analytes in tears
WO2004046726A3 (en) Methods and kits for assays of rapid screening of diabetes
DE602004028020D1 (de) Ophthalmischer sensor
WO2008014132A3 (en) Combination analyte measurement device and method of use
EP1599131B1 (de) Vorrichtung zur messung der konzentration eines analyts in einer augenflüssigkeit
WO2003055382A3 (de) Verfahren und vorrichtung zur bestimmung eines lichttransportparameters in einer biologischen matrix
NO332247B1 (no) Optisk sensor inneholdende partikler for in situ maling av analytter
WO2005012553A3 (en) Optical in vivo probe of analyte concentration within the sterile matrix under the human nail
WO2004056278A3 (en) Method for diagnosing a disease state using ocular characteristics
WO1999057306A3 (en) Method for diagnosing a vascular condition
Wingert et al. Clinical evaluation of five portable tonometers
US5869231A (en) Method for reproducibly determining the components of lacrimal fluid
WO2004093640A3 (en) Load sensing applanation tonometer
Bauer et al. Non-invasive assessment of ocular pharmacokinetics using confocal Raman spectroscopy
RU2008129048A (ru) Устройство с трансдермальными датчиками аналитов и способы его применения

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties