ATE287700T1 - Strahlung-sensitive liposomen - Google Patents

Strahlung-sensitive liposomen

Info

Publication number
ATE287700T1
ATE287700T1 AT00988017T AT00988017T ATE287700T1 AT E287700 T1 ATE287700 T1 AT E287700T1 AT 00988017 T AT00988017 T AT 00988017T AT 00988017 T AT00988017 T AT 00988017T AT E287700 T1 ATE287700 T1 AT E287700T1
Authority
AT
Austria
Prior art keywords
liposome
radiation
liposomal
present
sensitive liposomes
Prior art date
Application number
AT00988017T
Other languages
English (en)
Inventor
David F O'brien
Kathy A Mcgovern
Bruce Bondurant
Robert M Sutherland
Original Assignee
Univ Arizona
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Arizona filed Critical Univ Arizona
Application granted granted Critical
Publication of ATE287700T1 publication Critical patent/ATE287700T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0009—Galenical forms characterised by the drug release technique; Application systems commanded by energy involving or responsive to electricity, magnetism or acoustic waves; Galenical aspects of sonophoresis, iontophoresis, electroporation or electroosmosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
    • A61K9/1273—Polymersomes; Liposomes with polymerisable or polymerised bilayer-forming substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dispersion Chemistry (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Neurosurgery (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Radiation-Therapy Devices (AREA)
AT00988017T 1999-11-30 2000-11-30 Strahlung-sensitive liposomen ATE287700T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US16810099P 1999-11-30 1999-11-30
PCT/US2000/032902 WO2001039744A2 (en) 1999-11-30 2000-11-30 Radiation sensitive liposomes

Publications (1)

Publication Number Publication Date
ATE287700T1 true ATE287700T1 (de) 2005-02-15

Family

ID=22610124

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00988017T ATE287700T1 (de) 1999-11-30 2000-11-30 Strahlung-sensitive liposomen

Country Status (7)

Country Link
US (4) US6989153B2 (de)
EP (1) EP1233752B1 (de)
JP (2) JP4829454B2 (de)
AT (1) ATE287700T1 (de)
AU (1) AU2427601A (de)
DE (1) DE60017787T2 (de)
WO (1) WO2001039744A2 (de)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE287700T1 (de) 1999-11-30 2005-02-15 Univ Arizona Strahlung-sensitive liposomen
US8071740B2 (en) 2000-11-17 2011-12-06 Vascular Biogenics Ltd. Promoters exhibiting endothelial cell specificity and methods of using same for regulation of angiogenesis
US6838452B2 (en) 2000-11-24 2005-01-04 Vascular Biogenics Ltd. Methods employing and compositions containing defined oxidized phospholipids for prevention and treatment of atherosclerosis
US20060014013A1 (en) * 2001-03-10 2006-01-19 Saavedra Steven S Stabilized biocompatible supported lipid membrane
CA2449054C (en) * 2001-05-30 2011-01-04 The Scripps Research Institute Integrin targeting liposome for nucleic acid delivery
CA2463816C (en) 2001-10-19 2014-07-08 Vascular Biogenics Ltd. Polynucleotide constructs, pharmaceutical compositions and methods for targeted downregulation of angiogenesis and anticancer therapy
AR036316A1 (es) * 2002-08-29 2004-08-25 Monte Verde S A Una composicion farmaceutica de liposomas de tamano pequeno y metodo de preparacion
FR2848854B1 (fr) * 2002-12-24 2005-03-18 Coletica Particules comprenant un biopolymere degradable sous l'effet d'une onde electromagnetique telle qu'emise par un rayonnement solaire
US7711313B2 (en) * 2004-05-14 2010-05-04 Google Inc. Broadcast monitoring system and method for intelligent optimization
EP1600153A1 (de) * 2004-05-26 2005-11-30 Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts Wirkstoffabgabe-Überwachung ermöglichende pharmazeutische Zusammensetzung mit verzögerter Freisetzung
US7807847B2 (en) 2004-07-09 2010-10-05 Vascular Biogenics Ltd. Process for the preparation of oxidized phospholipids
US20090317455A1 (en) * 2006-08-31 2009-12-24 Naoto Oku Reverse targeting lipid vesicle
US9006217B2 (en) 2007-01-09 2015-04-14 Vascular Biogenics Ltd. High-purity phospholipids
US8569529B2 (en) 2007-01-09 2013-10-29 Vascular Biogenics Ltd. High-purity phospholipids
US20100104628A1 (en) * 2007-03-28 2010-04-29 Duke University method of treating neuroblastoma
US8784846B2 (en) * 2007-07-30 2014-07-22 Loma Linda University Medical Center Systems and methods for particle radiation enhanced delivery of therapy
JP5370153B2 (ja) * 2007-08-20 2013-12-18 コニカミノルタ株式会社 造影剤用化合物含有糖修飾リポソーム及び造影剤
WO2009042839A1 (en) * 2007-09-28 2009-04-02 Varian Medical Systems, Inc. Radiation sensitive liposomes
JP5207169B2 (ja) * 2007-10-18 2013-06-12 独立行政法人日本原子力研究開発機構 電離放射線分解性リポソーム、それを用いたリポソーム製剤、並びにリポソームの調整方法
JP5752599B2 (ja) 2008-11-06 2015-07-22 ヴァスキュラー バイオジェニックス リミテッド 酸化脂質化合物およびその使用
US8808733B2 (en) 2009-03-31 2014-08-19 The Board Of Trustees Of The University Of Arkansas Method of controlled drug release from a liposome carrier
UY32560A (es) 2009-04-29 2010-11-30 Bayer Schering Pharma Ag Inmunoconjugados de antimesotelina y usos de los mismos
WO2010135714A2 (en) 2009-05-22 2010-11-25 The Methodist Hospital Research Institute Methods for modulating adipocyte expression using microrna compositions
AU2012239888B9 (en) * 2011-04-06 2017-10-12 Alzeca Biosciences, LLC Lipid-based nanoparticles
US9849087B2 (en) 2011-11-08 2017-12-26 The Board Of Trustees Of The University Of Arkansas Methods and compositions for X-ray induced release from pH sensitive liposomes
JP6130401B2 (ja) 2012-01-20 2017-05-17 アンナプラガダ，アナンス 医学画像を客観的に特徴付けるための方法および組成物
US9993553B2 (en) 2013-03-14 2018-06-12 The Regents Of The University Of California Methods and compositions for targeted release of molecules from nanoscale carriers
EP3174544B1 (de) * 2014-07-31 2020-12-09 Universita' Degli Studi Di Cagliari Ester eines phospholipids mit konjugierter linolsäure zur behandlung von psychiatrischen störungen mit neuroinflammatorischer und neurodegenerativer basis
KR102409017B1 (ko) 2014-10-08 2022-06-16 텍사스 칠드런스 하스피탈 리포좀을 이용한 아밀로이드 플라크의 mri 영상화
US9771385B2 (en) 2014-11-26 2017-09-26 Vascular Biogenics Ltd. Oxidized lipids
ES2855299T3 (es) 2014-11-26 2021-09-23 Vascular Biogenics Ltd Lípidos oxidados y tratamiento o prevención de la fibrosis
US10842746B1 (en) 2016-08-25 2020-11-24 Verily Life Sciences Llc Bi-directionally crosslinked liposomes and method of making same
EP3934752A1 (de) 2019-03-08 2022-01-12 Mevion Medical Systems, Inc. Abgabe von strahlung durch eine säule und erzeugung eines behandlungsplanes dafür
WO2022092411A1 (ko) * 2020-10-30 2022-05-05 가천대학교 산학협력단 대식작용 추적 pet 이미징을 위한 리포좀 및 이를 포함하는 나노 프로브
EP4356930A1 (de) 2022-10-21 2024-04-24 Universite De Bordeaux Lichtempfindliche diazirinkonjugierte phospholipide und deren verwendungen
KR20260040011A (ko) * 2023-06-28 2026-03-23 사노피 백신즈 유에스 인크. 핵산 전달을 위한 헬퍼 지질

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5061484A (en) * 1988-03-11 1991-10-29 Alpha Therapeutic Corporation Perfluorochemical emulsion with stabilized vesicles
US20020150539A1 (en) * 1989-12-22 2002-10-17 Unger Evan C. Ultrasound imaging and treatment
US5088499A (en) 1989-12-22 1992-02-18 Unger Evan C Liposomes as contrast agents for ultrasonic imaging and methods for preparing the same
FR2694559B1 (fr) * 1992-08-06 1994-10-28 Atta Nouveaux dérivés amphiphiles d'aminoacides ou de peptides, leur procédé de préparation et leur utilisation dans des préparations à usage biomédical.
US5366881A (en) * 1993-02-23 1994-11-22 The United States Of America As Represented By The Secretary Of The Navy Polymerizable lipids for preparing vesicles that controllably release an encapsulant
US6531156B1 (en) * 1994-04-15 2003-03-11 Temple University Aqueous solven encapsulation method, apparatus and microcapsules
US20020010144A1 (en) * 1994-04-29 2002-01-24 Robert Sobol Enhancing the sensitivity of tumor cells to therapies
US6080423A (en) * 1994-08-11 2000-06-27 Regents Of The University Of California Three dimensional colorimetric assay assemblies
US5885613A (en) 1994-09-30 1999-03-23 The University Of British Columbia Bilayer stabilizing components and their use in forming programmable fusogenic liposomes
US6090800A (en) * 1997-05-06 2000-07-18 Imarx Pharmaceutical Corp. Lipid soluble steroid prodrugs
US6159443A (en) * 1999-04-29 2000-12-12 Vanderbilt University X-ray guided drug delivery
ATE287700T1 (de) 1999-11-30 2005-02-15 Univ Arizona Strahlung-sensitive liposomen
GB0518890D0 (en) * 2005-09-15 2005-10-26 Ucl Biomedica Plc Method of determining damage to skin
US20080314767A1 (en) * 2007-06-22 2008-12-25 Bausch & Lomb Incorporated Ophthalmic Solutions

Also Published As

Publication number Publication date
US6989153B2 (en) 2006-01-24
US20020064554A1 (en) 2002-05-30
US20060099141A1 (en) 2006-05-11
US8535712B2 (en) 2013-09-17
DE60017787T2 (de) 2006-01-05
JP2003515550A (ja) 2003-05-07
US20110217236A1 (en) 2011-09-08
EP1233752B1 (de) 2005-01-26
WO2001039744A3 (en) 2002-01-24
AU2427601A (en) 2001-06-12
EP1233752A2 (de) 2002-08-28
JP4829454B2 (ja) 2011-12-07
US20130053618A1 (en) 2013-02-28
JP2011173896A (ja) 2011-09-08
DE60017787D1 (de) 2005-03-03
WO2001039744A2 (en) 2001-06-07

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