ATE423547T1 - N-acyl-phosphatidylethanolamin-vermittelte wirkstoffdarreichung in liposomenform - Google Patents
N-acyl-phosphatidylethanolamin-vermittelte wirkstoffdarreichung in liposomenformInfo
- Publication number
- ATE423547T1 ATE423547T1 AT97945550T AT97945550T ATE423547T1 AT E423547 T1 ATE423547 T1 AT E423547T1 AT 97945550 T AT97945550 T AT 97945550T AT 97945550 T AT97945550 T AT 97945550T AT E423547 T1 ATE423547 T1 AT E423547T1
- Authority
- AT
- Austria
- Prior art keywords
- phosphatidylethanolamine
- acyl
- active ingredient
- liposome form
- ingredient dosage
- Prior art date
Links
- 239000002502 liposome Substances 0.000 title abstract 3
- 239000004480 active ingredient Substances 0.000 title 1
- 239000012867 bioactive agent Substances 0.000 abstract 1
- 150000008104 phosphatidylethanolamines Chemical class 0.000 abstract 1
- 229940067605 phosphatidylethanolamines Drugs 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
- A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S424/00—Drug, bio-affecting and body treating compositions
- Y10S424/812—Liposome comprising an antibody, antibody fragment, antigen, or other specific or nonspecific immunoeffector
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/829—Liposomes, e.g. encapsulation
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T428/00—Stock material or miscellaneous articles
- Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
- Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
- Y10T428/2984—Microcapsule with fluid core [includes liposome]
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Dispersion Chemistry (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Cosmetics (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US2855796P | 1996-10-15 | 1996-10-15 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE423547T1 true ATE423547T1 (de) | 2009-03-15 |
Family
ID=21844115
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT97945550T ATE423547T1 (de) | 1996-10-15 | 1997-10-15 | N-acyl-phosphatidylethanolamin-vermittelte wirkstoffdarreichung in liposomenform |
Country Status (13)
| Country | Link |
|---|---|
| US (2) | US6120797A (de) |
| EP (1) | EP0966267B1 (de) |
| AT (1) | ATE423547T1 (de) |
| AU (1) | AU725257B2 (de) |
| CA (1) | CA2276269C (de) |
| DE (1) | DE69739277D1 (de) |
| ES (1) | ES2321769T3 (de) |
| HU (1) | HUP0000522A3 (de) |
| IL (1) | IL130822A (de) |
| NO (1) | NO993257L (de) |
| NZ (2) | NZ514133A (de) |
| SK (1) | SK283760B6 (de) |
| WO (1) | WO1998016199A1 (de) |
Families Citing this family (63)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2343767T3 (es) | 1997-09-18 | 2010-08-09 | Pacira Pharmaceuticals, Inc. | Composiciones anestesicas liposomicas de liberacion sostenida. |
| JP4575592B2 (ja) | 1997-11-14 | 2010-11-04 | パシラ ファーマシューティカルズ インコーポレーテッド | 多小胞リポソームの製造 |
| US6979456B1 (en) | 1998-04-01 | 2005-12-27 | Jagotec Ag | Anticancer compositions |
| WO2000003660A1 (en) | 1998-07-17 | 2000-01-27 | Skyepharma, Inc. | Biodegradable compositions for the controlled release of encapsulated substances |
| JP4198318B2 (ja) | 1998-08-19 | 2008-12-17 | ヤーゴテック アクチェンゲゼルシャフト | プロポフォールの注射可能水性分散物 |
| EP1419252A2 (de) * | 2001-04-04 | 2004-05-19 | Merrion Research I Limited | Genetische analyse der peyer'schen plaques und m zellen und verfahren und zusammensetzungen zur targeting der peyer'schen plaques und m zellen |
| US20030096000A1 (en) * | 2001-05-31 | 2003-05-22 | Solis Rosa Maria | Encapsulation of nanosuspensions in liposomes and microspheres |
| WO2003047499A2 (en) | 2001-12-04 | 2003-06-12 | Ben Gurion University Of The Negev Research And Development Authority | Amphiphilic compounds and vesicles/liposomes for organ-specific drug targeting |
| EP1471885A4 (de) * | 2002-01-09 | 2009-04-22 | Transave Inc | Wirkungsvolle liposom-verkapselung |
| US20060062839A1 (en) * | 2002-01-09 | 2006-03-23 | Elan Pharmaceuticals, Inc. | Efficient liposomal encapsulation under mild conditions |
| WO2003059322A1 (en) * | 2002-01-09 | 2003-07-24 | Elan Pharmaceuticals, Inc. | Efficient nucleic acid encapsulation into medium sized liposomes |
| CA2475630C (en) * | 2002-02-12 | 2011-01-18 | Hunza Di Pistolesi Elvira & C. S.A.S. | N-acyl-phosphatidyl-ethanolamines and/or mixtures of n-acyl-ethanolamines with phosphatidic acids or lysophosphatidic acids |
| DE60335469D1 (de) * | 2002-07-02 | 2011-02-03 | Univ Texas | Radioaktiv markierte verbindungen und liposome und ihre herstellungs- und anwendungsverfahren |
| ITMI20021455A1 (it) * | 2002-07-02 | 2004-01-02 | Ugo Raffaello Citernesi | Formulazioni fosfolipidiche di lexitropsine loro preparazione ed impiego terapeutico |
| WO2005011708A1 (en) * | 2003-07-31 | 2005-02-10 | The Board Of Regents Of The University Of Texas System | Compositions and methods for treating, preventing and/or ameliorating cancers, the onset of cancers or the symptoms of cancers |
| US8062891B2 (en) | 2003-10-24 | 2011-11-22 | Gencia Corporation | Nonviral vectors for delivering polynucleotides to plants |
| WO2005056752A2 (en) | 2003-10-24 | 2005-06-23 | Gencia Corporation | Methods and compositions for delivering polynucleotides |
| US20090123468A1 (en) | 2003-10-24 | 2009-05-14 | Gencia Corporation | Transducible polypeptides for modifying metabolism |
| US8133733B2 (en) | 2003-10-24 | 2012-03-13 | Gencia Corporation | Nonviral vectors for delivering polynucleotides to target tissues |
| US8507277B2 (en) | 2003-10-24 | 2013-08-13 | Gencia Corporation | Nonviral vectors for delivering polynucleotides |
| ITMI20041280A1 (it) * | 2004-06-24 | 2004-09-24 | Hunza Di Pistolesi Elvira & C | Preparazione farmaceutiche dietetiche e-o cosmetiche per il trattamento dell'obesita' dell'alopecia della cellulite e dell'invecchiamento cutaneo |
| JP2006248978A (ja) * | 2005-03-10 | 2006-09-21 | Mebiopharm Co Ltd | 新規なリポソーム製剤 |
| US7846445B2 (en) * | 2005-09-27 | 2010-12-07 | Amunix Operating, Inc. | Methods for production of unstructured recombinant polymers and uses thereof |
| US20090099031A1 (en) * | 2005-09-27 | 2009-04-16 | Stemmer Willem P | Genetic package and uses thereof |
| WO2007038619A2 (en) * | 2005-09-27 | 2007-04-05 | Amunix, Inc. | Proteinaceous pharmaceuticals and uses thereof |
| US7855279B2 (en) * | 2005-09-27 | 2010-12-21 | Amunix Operating, Inc. | Unstructured recombinant polymers and uses thereof |
| JP5738516B2 (ja) | 2005-12-30 | 2015-06-24 | ゼンサン (シャンハイ) サイエンス アンド テクノロジー リミテッド | 心機能改善のためのニューレグリンの徐放 |
| WO2008030818A2 (en) * | 2006-09-05 | 2008-03-13 | Mebiopharm Co., Ltd. | Novel liposome compositions |
| JP2010513354A (ja) * | 2006-12-19 | 2010-04-30 | ノヴォソム アクチェンゲゼルシャフト | トランスフェクションエンハンサー要素を含む脂質および脂質集合体 |
| MX2010001684A (es) * | 2007-08-15 | 2010-04-21 | Amunix Inc | Composiciones y metodos para modificar propiedades de polipeptidos biologicamente activos. |
| WO2010004597A1 (en) * | 2008-07-08 | 2010-01-14 | Chemi Spa | Rocess for the production of n-acyl-phosphatidyl-etanolamine |
| CN108530543B (zh) | 2009-02-03 | 2023-06-23 | 阿穆尼克斯制药公司 | 延伸重组多肽和包含该延伸重组多肽的组合物 |
| DK2440241T3 (en) | 2009-06-08 | 2017-10-02 | Amunix Operating Inc | GROWTH HORMON POLYPEPTIDES AND PROCEDURES FOR PREPARING AND USING THEREOF |
| JP5839597B2 (ja) | 2009-06-08 | 2016-01-06 | アムニクス オペレーティング インコーポレイテッド | グルコース調節ポリペプチド並びにその作成及び使用方法 |
| CN102741275B (zh) | 2009-08-24 | 2016-08-03 | 阿穆尼克斯运营公司 | 凝血因子ix组合物及其制备和使用方法 |
| CN106619515A (zh) | 2009-08-27 | 2017-05-10 | 工业研究与发展基金会有限公司 | 脂质体组合物及其用途 |
| BR112012009801A8 (pt) | 2009-10-30 | 2016-08-30 | Cns Therapeutics Inc | Polipeptídeo neurturina e variante de neurturina |
| WO2012094727A1 (en) * | 2010-10-29 | 2012-07-19 | The Governing Council Of The University Of Toronto | Lipid encapsulation of surface enhanced raman scattering (sers) nanoparticles |
| LT3564260T (lt) | 2012-02-15 | 2023-01-10 | Bioverativ Therapeutics Inc. | Viii faktoriaus kompozicijos ir jų gamybos bei panaudojimo būdai |
| EP2822577B1 (de) | 2012-02-15 | 2019-02-06 | Bioverativ Therapeutics Inc. | Rekombinante faktor-viii-proteine |
| TWI667255B (zh) | 2013-08-14 | 2019-08-01 | 美商生物化學醫療公司 | 因子viii-xten融合物及其用途 |
| SG11201605242YA (en) | 2014-01-10 | 2016-07-28 | Biogen Ma Inc | Factor viii chimeric proteins and uses thereof |
| CA2943190A1 (en) | 2014-03-25 | 2015-10-01 | The Government Of The United States Of America As Represented By The Secretary Of The Army | Non-toxic adjuvant formulation comprising a monophosphoryl lipid a (mpla)-containing liposome composition and a saponin |
| IL257231B (en) | 2015-08-03 | 2022-09-01 | Bioverativ Therapeutics Inc | Factor ix fusion proteins and methods of making and using same |
| IL286493B (en) | 2015-11-06 | 2022-07-01 | Memorial Sloan Kettering Cancer Center | Triterpene saponin analogues, methods of producing same, compositions comprising same and uses thereof |
| JP7041673B2 (ja) * | 2016-10-13 | 2022-03-24 | カーノット, エルエルシー | N-アシルエタノールアミド誘導体およびその使用 |
| MX2019006444A (es) | 2016-12-02 | 2019-10-30 | Bioverativ Therapeutics Inc | Métodos de tratamiento de artropatía hemofílica utilizando factores de coagulación quiméricos. |
| AU2018258070A1 (en) | 2017-04-25 | 2019-10-24 | Adjuvance Technologies, Inc. | Triterpene saponin analogues |
| ES3052812T3 (en) | 2017-05-08 | 2026-01-14 | Flagship Pioneering Innovations V Inc | Compositions for facilitating membrane fusion and uses thereof |
| WO2019079160A1 (en) | 2017-10-16 | 2019-04-25 | Adjuvance Technologies, Inc. | TRITERPENIC SAPONIN ANALOGS |
| SI3793588T1 (sl) | 2018-05-18 | 2025-07-31 | Bioverativ Therapeutics Inc. | Postopki zdravljenja hemofilije A |
| AU2019378036B2 (en) | 2018-11-14 | 2026-05-07 | Flagship Pioneering Innovations V, Inc | Compositions and methods for compartment-specific cargo delivery |
| IL298815A (en) | 2020-06-25 | 2023-02-01 | Amunix Pharmaceuticals Inc | Bispecific compositions targeting HER-2 and methods for their preparation and use |
| US11033495B1 (en) | 2021-01-22 | 2021-06-15 | Pacira Pharmaceuticals, Inc. | Manufacturing of bupivacaine multivesicular liposomes |
| US12151024B2 (en) | 2021-01-22 | 2024-11-26 | Pacira Pharmaceuticals, Inc. | Manufacturing of bupivacaine multivesicular liposomes |
| US11278494B1 (en) | 2021-01-22 | 2022-03-22 | Pacira Pharmaceuticals, Inc. | Manufacturing of bupivacaine multivesicular liposomes |
| US11357727B1 (en) | 2021-01-22 | 2022-06-14 | Pacira Pharmaceuticals, Inc. | Manufacturing of bupivacaine multivesicular liposomes |
| GB2627096A (en) | 2021-10-14 | 2024-08-14 | Pacira Pharmaceuticals Inc | Bupivacaine multivesicular liposome formulations and uses thereof |
| MX2024010416A (es) | 2022-03-14 | 2024-09-05 | Pfizer | Metodos de produccion de un adyuvante. |
| WO2025057058A1 (en) | 2023-09-13 | 2025-03-20 | Pfizer Inc. | Methods for producing an adjuvant |
| US12251468B1 (en) | 2024-05-20 | 2025-03-18 | Pacira Pharmaceuticals, Inc. | Manufacturing of bupivacaine multivesicular liposomes |
| US12246092B1 (en) | 2024-05-20 | 2025-03-11 | Pacira Pharmaceuticals, Inc. | Manufacturing of bupivacaine multivesicular liposomes |
| US12251472B1 (en) | 2024-05-20 | 2025-03-18 | Pacira Pharmaceuticals, Inc. | Manufacturing of bupivacaine multivesicular liposomes |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4610868A (en) * | 1984-03-20 | 1986-09-09 | The Liposome Company, Inc. | Lipid matrix carriers for use in drug delivery systems |
| CA1338702C (en) * | 1987-03-05 | 1996-11-12 | Lawrence D. Mayer | High drug:lipid formulations of liposomal- antineoplastic agents |
-
1997
- 1997-10-15 WO PCT/US1997/018112 patent/WO1998016199A1/en not_active Ceased
- 1997-10-15 SK SK993-99A patent/SK283760B6/sk unknown
- 1997-10-15 DE DE69739277T patent/DE69739277D1/de not_active Expired - Lifetime
- 1997-10-15 AT AT97945550T patent/ATE423547T1/de not_active IP Right Cessation
- 1997-10-15 IL IL13082297A patent/IL130822A/xx not_active IP Right Cessation
- 1997-10-15 AU AU46723/97A patent/AU725257B2/en not_active Ceased
- 1997-10-15 NZ NZ514133A patent/NZ514133A/en unknown
- 1997-10-15 ES ES97945550T patent/ES2321769T3/es not_active Expired - Lifetime
- 1997-10-15 US US08/951,056 patent/US6120797A/en not_active Expired - Fee Related
- 1997-10-15 HU HU0000522A patent/HUP0000522A3/hu unknown
- 1997-10-15 NZ NZ336538A patent/NZ336538A/en unknown
- 1997-10-15 CA CA002276269A patent/CA2276269C/en not_active Expired - Fee Related
- 1997-10-15 EP EP97945550A patent/EP0966267B1/de not_active Expired - Lifetime
-
1999
- 1999-06-30 NO NO993257A patent/NO993257L/no unknown
-
2000
- 2000-01-19 US US09/487,053 patent/US6294191B1/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| NZ336538A (en) | 2001-11-30 |
| IL130822A0 (en) | 2001-07-24 |
| DE69739277D1 (de) | 2009-04-09 |
| CA2276269C (en) | 2008-09-02 |
| WO1998016199A1 (en) | 1998-04-23 |
| ES2321769T3 (es) | 2009-06-10 |
| NO993257D0 (no) | 1999-06-30 |
| HUP0000522A1 (hu) | 2000-09-28 |
| US6120797A (en) | 2000-09-19 |
| AU725257B2 (en) | 2000-10-12 |
| AU4672397A (en) | 1998-05-11 |
| NO993257L (no) | 1999-07-28 |
| CA2276269A1 (en) | 1998-04-23 |
| NZ514133A (en) | 2001-09-28 |
| US6294191B1 (en) | 2001-09-25 |
| SK99399A3 (en) | 2000-06-12 |
| EP0966267A4 (de) | 2006-02-01 |
| SK283760B6 (sk) | 2004-01-08 |
| HUP0000522A3 (en) | 2000-10-30 |
| IL130822A (en) | 2005-12-18 |
| EP0966267A1 (de) | 1999-12-29 |
| EP0966267B1 (de) | 2009-02-25 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DE69739277D1 (de) | N-acyl-phosphatidylethanolamin-vermittelte wirkstoffdarreichung in liposomenform | |
| PT1093819E (pt) | Compostos e composicoes para fornecimento de agentes activos | |
| IL140710A0 (en) | Pulmonary delivery of active agents | |
| ES2161085T3 (es) | Formulaciones que contienen oxaliplatino. | |
| FI954990A0 (fi) | Aktiiviainetta sisältävä transdermaalinen valmiste | |
| FR2784294B1 (fr) | Composition cosmetique et/ou dermatologique renfermant au moins un extrait de murier, au moins un extrait de scutellaire et au moins un derive d'acide salicylique | |
| AU3559895A (en) | Polyethylene glycol modified ceramide lipids and liposome uses thereof | |
| SE9704546D0 (sv) | Novel compounds | |
| DE69905170D1 (en) | Thiazolopyrimidinderivate | |
| DE60138566D1 (en) | Selbstformende thermodynamisch stabile liposome | |
| TR200001203T2 (tr) | Yeni birleşik maddeler | |
| IL128801A0 (en) | Combination of no synthase inhibitors and traps of reactive forms of oxygen | |
| TR200100366T2 (tr) | Aktif madde dağıtmaya mahsus bileşikler ve bileşimler. | |
| DK0960107T3 (da) | 6-Thiosubstituerede paclitaxeler | |
| ES2108698T3 (es) | Liposomas exentos de sustancias activas, para el tratamiento de aterosclerosis. | |
| WO1999047101A3 (en) | Compositions containing lysophosphatidic acids which inhibit apoptosis and uses thereof | |
| IL139318A0 (en) | Sugar alcohol mixtures as therapeutic agents and pharmaceutical compositions containing the same | |
| ES2071995T3 (es) | Composicion para la activacion de macrofagia. | |
| ATE345778T1 (de) | (ester)-lysolecithine in liposomen | |
| BR9810433A (pt) | Composições anti-helmìnticas | |
| BR9812002A (pt) | Compostos com efeito antiprimeiro-passe | |
| SE9701184D0 (sv) | Substanser för att åstadkomma preferens och skapa acceptans | |
| GB9818445D0 (en) | Medicaments | |
| MX9705592A (es) | Composiciones farmaceuticas que contienen corticosteroides y preparacion de las mismas. | |
| ITRM980392A0 (it) | Plasmide per la produzione di peptidi antimicrobici in batteri ricombinati |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |