ATE287724T1 - Verfahren zur vorbeugung und behandlung von beschädigung des schleimhautgewebes - Google Patents

Verfahren zur vorbeugung und behandlung von beschädigung des schleimhautgewebes

Info

Publication number: ATE287724T1
Authority: AT; Austria
Prior art keywords: analogues; aii; preventing; treating damage; mucous tissue
Prior art date: 1999-12-16

Application number

AT00980704T

Other languages

English (en)

Inventor

Kathleen E Rodgers

Gere S Dizerega

Original Assignee

Univ Southern California

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1999-12-16

Filing date

2000-11-27

Publication date

2005-02-15

2000-11-27 Application filed by Univ Southern California filed Critical Univ Southern California

2005-02-15 Application granted granted Critical

2005-02-15 Publication of ATE287724T1 publication Critical patent/ATE287724T1/de

Links

CZGUSIXMZVURDU-JZXHSEFVSA-N Ile(5)-angiotensin II Chemical compound C([C@@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC=1NC=NC=1)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CC=1C=CC=CC=1)C([O-])=O)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(N)=[NH2+])NC(=O)[C@@H]([NH3+])CC([O-])=O)C(C)C)C1=CC=C(O)C=C1 CZGUSIXMZVURDU-JZXHSEFVSA-N 0.000 abstract 5
ORWYRWWVDCYOMK-HBZPZAIKSA-N angiotensin I Chemical compound C([C@@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC=1NC=NC=1)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N[C@@H](CC=1NC=NC=1)C(=O)N[C@@H](CC(C)C)C(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CC(O)=O)C(C)C)C1=CC=C(O)C=C1 ORWYRWWVDCYOMK-HBZPZAIKSA-N 0.000 abstract 4
102000005862 Angiotensin II Human genes 0.000 abstract 3
101800000733 Angiotensin-2 Proteins 0.000 abstract 3
229950006323 angiotensin ii Drugs 0.000 abstract 3
101800000734 Angiotensin-1 Proteins 0.000 abstract 2
102400000344 Angiotensin-1 Human genes 0.000 abstract 2
102000004881 Angiotensinogen Human genes 0.000 abstract 1
108090001067 Angiotensinogen Proteins 0.000 abstract 1
210000004400 mucous membrane Anatomy 0.000 abstract 1
239000008194 pharmaceutical composition Substances 0.000 abstract 1
239000000018 receptor agonist Substances 0.000 abstract 1
229940044601 receptor agonist Drugs 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/14—Angiotensins: Related peptides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
- A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
- A61K31/704—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/193—Colony stimulating factors [CSF]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/02—Drugs for genital or sexual disorders; Contraceptives for disorders of the vagina
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Immunology (AREA)
Epidemiology (AREA)
Communicable Diseases (AREA)
Pulmonology (AREA)
Oncology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Molecular Biology (AREA)
Biophysics (AREA)
Transplantation (AREA)
Otolaryngology (AREA)
Endocrinology (AREA)
Vascular Medicine (AREA)
Biochemistry (AREA)
Virology (AREA)
Genetics & Genomics (AREA)
Gynecology & Obstetrics (AREA)
Reproductive Health (AREA)
Zoology (AREA)
Gastroenterology & Hepatology (AREA)
Urology & Nephrology (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Peptides Or Proteins (AREA)
Disintegrating Or Milling (AREA)
Materials For Medical Uses (AREA)

AT00980704T 1999-12-16 2000-11-27 Verfahren zur vorbeugung und behandlung von beschädigung des schleimhautgewebes ATE287724T1 (de)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US17124999P	1999-12-16	1999-12-16
US21322400P	2000-06-19	2000-06-19
PCT/US2000/032141 WO2001043761A2 (en)	1999-12-16	2000-11-27	Methods for treating and preventing damage to mucosal tissue

Publications (1)

Publication Number	Publication Date
ATE287724T1 true ATE287724T1 (de)	2005-02-15

Family

ID=26866886

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT00980704T ATE287724T1 (de)	1999-12-16	2000-11-27	Verfahren zur vorbeugung und behandlung von beschädigung des schleimhautgewebes

Country Status (8)

Country	Link
EP (1)	EP1239867B1 (de)
JP (1)	JP3901520B2 (de)
AT (1)	ATE287724T1 (de)
AU (1)	AU1793101A (de)
CA (1)	CA2393755C (de)
DE (1)	DE60017793T2 (de)
MX (1)	MXPA02005993A (de)
WO (1)	WO2001043761A2 (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CN102861019B (zh)	2004-12-24	2016-05-25	诺华股份有限公司	治疗或预防神经性疼痛的药物
EP2952185A1 (de)	2006-03-20	2015-12-09	Spinifex Pharmaceuticals Pty Ltd	Verfahren zur behandlung oder prophylaxe von entzündlichen schmerzen
AT508569A1 (de)	2009-07-23	2011-02-15	Affiris Ag	Pharmaceutical compound
US8557958B1 (en)	2012-06-18	2013-10-15	Tarix Pharmaceuticals Ltd.	Compositions and methods for treatment of diabetes
US8633158B1 (en)	2012-10-02	2014-01-21	Tarix Pharmaceuticals Ltd.	Angiotensin in treating brain conditions
US9333233B2 (en)	2014-02-25	2016-05-10	Tarix Pharmaceuticals Ltd.	Methods and compositions for the delayed treatment of stroke

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4377573A (en) *	1978-01-06	1983-03-22	Leveen Harry H	Method of control of gastrointestinal bleeding
DE3445932A1 (de) *	1984-12-17	1986-06-26	Boehringer Ingelheim KG, 6507 Ingelheim	Pharmazeutische zusammensetzungen
US5015629A (en) *	1989-06-26	1991-05-14	University Of Southern California	Tissue repair
US5955430A (en) *	1993-09-24	1999-09-21	University Of Southern California	Use of angiotensin II fragments and analogs thereof in tissue repair
US5567733B1 (en) *	1995-04-27	1999-08-24	Jon G Dishler	Irritation relief using nonsteroidal anti-inflammatory compounds
US5972887A (en) *	1996-09-19	1999-10-26	The Nemours Foundation	Treatment of intestinal epithelial cell malfunctions with Hepatocyte Growth Factor
SE9800550D0 (sv) *	1998-02-24	1998-02-24	A & Science Invest Ab	A pharmaceutical preparation comprising an angiotensin II type 2 receptor agonist, and use thereof

2000
- 2000-11-27 MX MXPA02005993A patent/MXPA02005993A/es unknown
- 2000-11-27 AT AT00980704T patent/ATE287724T1/de not_active IP Right Cessation
- 2000-11-27 CA CA2393755A patent/CA2393755C/en not_active Expired - Fee Related
- 2000-11-27 JP JP2001544898A patent/JP3901520B2/ja not_active Expired - Fee Related
- 2000-11-27 AU AU17931/01A patent/AU1793101A/en not_active Abandoned
- 2000-11-27 WO PCT/US2000/032141 patent/WO2001043761A2/en not_active Ceased
- 2000-11-27 DE DE60017793T patent/DE60017793T2/de not_active Expired - Lifetime
- 2000-11-27 EP EP00980704A patent/EP1239867B1/de not_active Expired - Lifetime

Also Published As

Publication number	Publication date
EP1239867A2 (de)	2002-09-18
JP3901520B2 (ja)	2007-04-04
AU1793101A (en)	2001-06-25
WO2001043761A2 (en)	2001-06-21
CA2393755A1 (en)	2001-06-21
DE60017793D1 (de)	2005-03-03
WO2001043761A3 (en)	2002-03-07
MXPA02005993A (es)	2002-10-23
EP1239867B1 (de)	2005-01-26
JP2003517019A (ja)	2003-05-20
CA2393755C (en)	2010-09-21
DE60017793T2 (de)	2006-01-05

Legal Events

Date	Code	Title	Description
2005-07-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties

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