ATE288280T1 - Verfahren zum blokieren von sec-rezeptoren - Google Patents

Verfahren zum blokieren von sec-rezeptoren

Info

Publication number: ATE288280T1
Authority: AT; Austria
Prior art keywords: blocking; sec; receptors; sec receptors; peptide
Prior art date: 1994-09-09

Application number

AT95931632T

Other languages

English (en)

Inventor

David H Perlmutter

Original Assignee

Univ Washington

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1994-09-09

Filing date

1995-09-07

Publication date

2005-02-15

1995-09-07 Application filed by Univ Washington filed Critical Univ Washington

2005-02-15 Application granted granted Critical

2005-02-15 Publication of ATE288280T1 publication Critical patent/ATE288280T1/de

Links

230000000903 blocking effect Effects 0.000 title abstract 2
108090000765 processed proteins & peptides Proteins 0.000 abstract 2
108010005584 serpin-enzyme complex receptor Proteins 0.000 abstract 2
102000013455 Amyloid beta-Peptides Human genes 0.000 abstract 1
108010090849 Amyloid beta-Peptides Proteins 0.000 abstract 1
230000002401 inhibitory effect Effects 0.000 abstract 1
230000002887 neurotoxic effect Effects 0.000 abstract 1
239000012622 synthetic inhibitor Substances 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/81—Protease inhibitors
- C07K14/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
- C07K14/811—Serine protease (E.C. 3.4.21) inhibitors
- C07K14/8121—Serpins
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/81—Protease inhibitors
- C07K14/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
- C07K14/811—Serine protease (E.C. 3.4.21) inhibitors
- C07K14/8121—Serpins
- C07K14/8125—Alpha-1-antitrypsin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
Molecular Biology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Genetics & Genomics (AREA)
Biophysics (AREA)
Biochemistry (AREA)
Gastroenterology & Hepatology (AREA)
Bioinformatics & Cheminformatics (AREA)
Neurosurgery (AREA)
Engineering & Computer Science (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Hospice & Palliative Care (AREA)
General Chemical & Material Sciences (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Psychiatry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
Peptides Or Proteins (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Electrical Discharge Machining, Electrochemical Machining, And Combined Machining (AREA)
Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
Indole Compounds (AREA)

AT95931632T 1994-09-09 1995-09-07 Verfahren zum blokieren von sec-rezeptoren ATE288280T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US08/306,872 US5514653A (en)	1994-09-09	1994-09-09	Method of blocking the SEC receptor
PCT/US1995/010989 WO1996007425A1 (en)	1994-09-09	1995-09-07	Method of blocking the sec receptor

Publications (1)

Publication Number	Publication Date
ATE288280T1 true ATE288280T1 (de)	2005-02-15

Family

ID=23187244

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT95931632T ATE288280T1 (de)	1994-09-09	1995-09-07	Verfahren zum blokieren von sec-rezeptoren

Country Status (8)

Country	Link
US (1)	US5514653A (de)
EP (1)	EP0781143B1 (de)
JP (1)	JPH10505086A (de)
AT (1)	ATE288280T1 (de)
AU (1)	AU3498795A (de)
CA (1)	CA2199180A1 (de)
DE (1)	DE69533988D1 (de)
WO (1)	WO1996007425A1 (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5792749A (en) *	1997-01-09	1998-08-11	Virginia Commonwealth University	Method and composition for lowering low density lipoprotein cholesterol
DE19725619A1 (de) *	1997-06-17	1998-12-24	Fraunhofer Ges Forschung	Peptide als Agonisten und/oder Inhibitoren der Amyloidbildung und Zytotoxizität sowie der Verwendung bei Alzheimer'schen Krankheit, beim Typ II Diabetes mellitus und bei spongiformen Encephalopathien
AU3511500A (en)	1999-03-05	2000-09-21	Trustees Of University Technology Corporation, The	Inhibitors of serine protease activity, methods and compositions for treatment of nitric oxide-induced clinical conditions
US6849605B1 (en)	1999-03-05	2005-02-01	The Trustees Of University Technology Corporation	Inhibitors of serine protease activity, methods and compositions for treatment of viral infections
AU3731400A (en)	1999-03-05	2000-09-21	Trustees Of University Technology Corporation, The	Methods and compositions useful in inhibiting apoptosis
AU3864000A (en) *	1999-03-05	2000-09-21	Trustees Of University Technology Corporation, The	Inhibitors of serine protease activity, methods and compositions for treatment of herpes viruses
KR20090016517A (ko)	1999-12-23	2009-02-13	벨루스 헬스 (인터내셔널) 리미티드	대뇌 아밀로이드 혈관병증을 조절하는 화합물 및 방법
DE10148553A1 (de) *	2001-10-01	2003-04-17	Protagen Ag	Proteinaseinhibitoren zur Therapie und Diagnose von neurodegenerativen Krankheiten
US20040220242A1 (en) *	2003-05-02	2004-11-04	Leland Shapiro	Inhibitors of serine protease activity, methods and compositions for treatment of nitric oxide induced clinical conditions
EP1660094A4 (de) *	2003-08-26	2009-09-16	Univ Colorado	Hemmer der serinprotease-aktivität und ihre verwendung bei verfahren und zusammensetzungen zur behandlung von bakterieninfektionen
CA2839917A1 (en)	2011-06-24	2012-12-27	The Regents Of The University Of Colorado, A Body Corporate	Compositions, methods and uses for alpha-1 antitrypsin fusion molecules
US9951104B2 (en)	2012-01-09	2018-04-24	Serpin Pharma, Llc	Peptides and methods of using same
AU2013202648B2 (en)	2012-01-10	2016-05-19	Konkuk University	Compositions, methods and uses for alpha-1 antitrypsin fusion molecules
EP3014726B1 (de)	2013-06-26	2017-07-19	TWS (Macau Commercial Offshore) Limited	Elektrisches energiespeichersystem
CA2996975C (en)	2015-08-28	2022-02-15	Serpin Pharma, Llc	Methods for treatment of diseases

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AU577259B2 (en) *	1982-08-13	1988-09-22	Zymogenetics Inc.	Glycolytic promters for regulated protein expression protease inhibitor
JPS60186290A (ja) *	1983-08-10	1985-09-21	チモ−ジエネテイツクス　インコ−ポレ−テツド	アルフア−１−アンチトリプシンを細菌に表現させる方法
US5157019A (en) *	1986-03-18	1992-10-20	Monsanto Company	Serine protease inhibitors
US5187153A (en) *	1986-11-17	1993-02-16	Scios Nova Inc.	Methods of treatment using Alzheimer's amyloid polypeptide derivatives
US5137873A (en) *	1990-07-27	1992-08-11	The Children's Medical Center Corporation	Substance p and tachykinin agonists for treatment of alzheimer's disease
US5164295A (en) *	1991-03-06	1992-11-17	The Upjohn Company	Method for identifying amyloid protein-extracellular matrix protein affinity altering compounds
US5175253A (en) *	1991-04-24	1992-12-29	Washington University	Binding peptides
US5604201A (en) *	1993-01-08	1997-02-18	State Of Oregon, Acting By And Through The Oregon State Board Of Higher Education On Behalf Of The Oregon Health Sciences University, A Non-Profit Organization	Methods and reagents for inhibiting furin endoprotease

1994
- 1994-09-09 US US08/306,872 patent/US5514653A/en not_active Expired - Fee Related
1995
- 1995-09-07 JP JP8509559A patent/JPH10505086A/ja not_active Ceased
- 1995-09-07 DE DE69533988T patent/DE69533988D1/de not_active Expired - Lifetime
- 1995-09-07 AU AU34987/95A patent/AU3498795A/en not_active Abandoned
- 1995-09-07 EP EP95931632A patent/EP0781143B1/de not_active Expired - Lifetime
- 1995-09-07 WO PCT/US1995/010989 patent/WO1996007425A1/en not_active Ceased
- 1995-09-07 CA CA002199180A patent/CA2199180A1/en not_active Abandoned
- 1995-09-07 AT AT95931632T patent/ATE288280T1/de not_active IP Right Cessation

Also Published As

Publication number	Publication date
EP0781143A1 (de)	1997-07-02
CA2199180A1 (en)	1996-03-14
EP0781143B1 (de)	2005-02-02
AU3498795A (en)	1996-03-27
DE69533988D1 (de)	2005-03-10
JPH10505086A (ja)	1998-05-19
WO1996007425A1 (en)	1996-03-14
US5514653A (en)	1996-05-07

Legal Events

Date	Code	Title	Description
2005-08-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties

Publication	Publication Date	Title
ATE288280T1 (de)	2005-02-15	Verfahren zum blokieren von sec-rezeptoren
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DE69018625D1 (de)	1995-05-18	Verfahren zum aufkonzentrieren von chlorgas.
DE69114199D1 (de)	1995-12-07	Verfahren zum Zementieren von Öl- und Gasbohrlöchern.
DE69522713D1 (de)	2001-10-18	Verfahren zum assoziieren von datentragenden objekten mit objekten der benutzerschnittstelle
DE69409775D1 (de)	1998-05-28	Zusammensetzung zum Beschichten von Kautschuk-Gegenständen
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DE68923481D1 (de)	1995-08-24	Verfahren zum Behandeln von Sojabohnen.
DE69801798D1 (de)	2001-10-31	Verfahren zur Dehydrierung von gesättigten aliphatischen Kohlenwasserstoffen in olefinischen Kohlenwasserstoffen
DE69627517D1 (de)	2003-05-22	Adaptiver regler zum spritzgiessen
DE59601109D1 (de)	1999-02-18	Verfahren zum behandeln von hausmüll
DE69615843D1 (de)	2001-11-15	Il-8 antagonisten zur behandlung von asthma
DE69625024D1 (de)	2003-01-09	Verfahren zum Nachweis von Protein im Harn
DE58906497D1 (de)	1994-02-03	Verfahren zum abdichten von schadhaften rohrleitungen.
DE3689766D1 (de)	1994-05-11	Monoklonaler antikörper-inhibitor des plasminogenaktivators, hybridomen, herstellung monoklonaler antikörper und deren verwendung zur reinigung, beseitigung, inhibition oder zum testverfahren von inhibitoren.
DE69408408D1 (de)	1998-03-12	Vorrichtung zum automatischen Umschalten von Rohrleitungen
DE69400735D1 (de)	1996-11-21	Vorrichtung zum Anbringen von Dichtungen
DE58906818D1 (de)	1994-03-10	Verfahren zum Desaktivieren von Radikalen.