ATE288423T1 - Benzoesäureester von oxazolidinonen, die hydroxyacetylpiperazin-gruppen tragen - Google Patents
Benzoesäureester von oxazolidinonen, die hydroxyacetylpiperazin-gruppen tragenInfo
- Publication number
- ATE288423T1 ATE288423T1 AT00980849T AT00980849T ATE288423T1 AT E288423 T1 ATE288423 T1 AT E288423T1 AT 00980849 T AT00980849 T AT 00980849T AT 00980849 T AT00980849 T AT 00980849T AT E288423 T1 ATE288423 T1 AT E288423T1
- Authority
- AT
- Austria
- Prior art keywords
- hydroxyacetylpiperazine
- oxazolidinones
- bearing
- groups
- benzoic acid
- Prior art date
Links
- IZXIZTKNFFYFOF-UHFFFAOYSA-N 2-Oxazolidone Chemical group O=C1NCCO1 IZXIZTKNFFYFOF-UHFFFAOYSA-N 0.000 title 1
- YKZWLZLFBNIZCC-UHFFFAOYSA-N 2-hydroxy-1-piperazin-1-ylethanone Chemical group OCC(=O)N1CCNCC1 YKZWLZLFBNIZCC-UHFFFAOYSA-N 0.000 title 1
- WPYMKLBDIGXBTP-UHFFFAOYSA-N benzoic acid Chemical class OC(=O)C1=CC=CC=C1 WPYMKLBDIGXBTP-UHFFFAOYSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
- C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D263/16—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D263/18—Oxygen atoms
- C07D263/20—Oxygen atoms attached in position 2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Ophthalmology & Optometry (AREA)
- Dermatology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US17067599P | 1999-12-14 | 1999-12-14 | |
| PCT/US2000/032432 WO2001044212A1 (en) | 1999-12-14 | 2000-12-06 | Benzoic acid esters of oxazolidinones having a hydroxyacetylpiperazine substituent |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE288423T1 true ATE288423T1 (de) | 2005-02-15 |
Family
ID=22620832
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT00980849T ATE288423T1 (de) | 1999-12-14 | 2000-12-06 | Benzoesäureester von oxazolidinonen, die hydroxyacetylpiperazin-gruppen tragen |
Country Status (26)
| Country | Link |
|---|---|
| US (1) | US6281210B1 (de) |
| EP (1) | EP1242395B1 (de) |
| JP (1) | JP2003516977A (de) |
| KR (1) | KR20020062332A (de) |
| CN (1) | CN1390211A (de) |
| AR (1) | AR026547A1 (de) |
| AT (1) | ATE288423T1 (de) |
| AU (1) | AU1805801A (de) |
| BR (1) | BR0015177A (de) |
| CA (1) | CA2387047A1 (de) |
| CO (1) | CO5261527A1 (de) |
| CZ (1) | CZ20022389A3 (de) |
| DE (1) | DE60017941T2 (de) |
| EA (1) | EA200200673A1 (de) |
| ES (1) | ES2236006T3 (de) |
| HU (1) | HUP0203787A3 (de) |
| IL (1) | IL150031A0 (de) |
| MX (1) | MXPA02005909A (de) |
| NO (1) | NO20022811L (de) |
| PE (1) | PE20010851A1 (de) |
| PL (1) | PL355369A1 (de) |
| PT (1) | PT1242395E (de) |
| SK (1) | SK5972002A3 (de) |
| TW (1) | TW544449B (de) |
| WO (1) | WO2001044212A1 (de) |
| ZA (1) | ZA200202953B (de) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9928568D0 (en) | 1999-12-03 | 2000-02-02 | Zeneca Ltd | Chemical compounds |
| DE19962924A1 (de) | 1999-12-24 | 2001-07-05 | Bayer Ag | Substituierte Oxazolidinone und ihre Verwendung |
| GB0009803D0 (en) | 2000-04-25 | 2000-06-07 | Astrazeneca Ab | Chemical compounds |
| ATE321024T1 (de) * | 2000-10-17 | 2006-04-15 | Pharmacia & Upjohn Co Llc | Verfahren zur herstellung von oxazolidinonverbindungen |
| DE10129725A1 (de) | 2001-06-20 | 2003-01-02 | Bayer Ag | Kombinationstherapie substituierter Oxazolidinone |
| TW200403240A (en) * | 2002-06-28 | 2004-03-01 | Upjohn Co | Difluorothioacetamides of oxazolidinones as antibacterial agents |
| TW200404069A (en) * | 2002-06-28 | 2004-03-16 | Upjohn Co | Difluorothioacetamides of oxazolidinones with a glycoloylpiperazine substituent |
| ATE344036T1 (de) * | 2002-11-21 | 2006-11-15 | Pharmacia & Upjohn Co Llc | N-(4-(piperazin-1-yl)-phenyl-2-oxazolidinon-5- carbonsäureamid-derivate und verwandte verbindungen als antibakterielle mittel |
| DE10300111A1 (de) * | 2003-01-07 | 2004-07-15 | Bayer Healthcare Ag | Verfahren zur Herstellung von 5-Chlor-N-({(5S)-2-oxo-3-[4-(3-oxo-4-morpholinyl)-phenyl]-1,3-oxazolidin-5-yl}-methyl)-2-thiophencarboxamid |
| DE10355461A1 (de) | 2003-11-27 | 2005-06-23 | Bayer Healthcare Ag | Verfahren zur Herstellung einer festen, oral applizierbaren pharmazeutischen Zusammensetzung |
| DE102004062475A1 (de) * | 2004-12-24 | 2006-07-06 | Bayer Healthcare Ag | Feste, oral applizierbare pharmazeutische Darreichungsformen mit modifizierter Freisetzung |
| EP1685841A1 (de) | 2005-01-31 | 2006-08-02 | Bayer Health Care Aktiengesellschaft | Prophylaxe und Behandlung von thrombolischen Erkrankungen |
| DE102005045518A1 (de) * | 2005-09-23 | 2007-03-29 | Bayer Healthcare Ag | 2-Aminoethoxyessigsäure-Derivate und ihre Verwendung |
| DE102005047561A1 (de) | 2005-10-04 | 2007-04-05 | Bayer Healthcare Ag | Feste, oral applizierbare pharmazeutische Darreichungsformen mit schneller Wirkstofffreisetzung |
| WO2007039132A1 (de) | 2005-10-04 | 2007-04-12 | Bayer Healthcare Ag | Neue polymorphe form und die amorphe form von 5-chlor-n- ( { ( 5s ) -2-0x0-3-[4-( 3-oxo-4-morpholinyl) - phenyl] -1,3-oxazolidin-5-yl} -methyl) -2- thiophencarboxamid |
| US20100210602A1 (en) * | 2006-12-12 | 2010-08-19 | The Johns Hopkins University | PhoU (PerF), A PERSISTENCE SWITCH INVOLVED IN PERSISTER FORMATION AND TOLERANCE TO MULTIPLE ANTIBIOTICS AND STRESSES AS A DRUG TARGET FOR PERSISTER BACTERIA |
| WO2009001192A2 (en) * | 2007-06-22 | 2008-12-31 | Orchid Research Laboratories Limited | Novel compounds and their use |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ274966A (en) * | 1993-11-22 | 1998-01-26 | Upjohn Co | Substituted-hydroxyacetyl piperazine phenyl oxazolidinone derivatives, use in pharmaceutical compositions |
| MY116093A (en) * | 1996-02-26 | 2003-11-28 | Upjohn Co | Azolyl piperazinyl phenyl oxazolidinone antimicrobials |
| FI19992555A7 (fi) * | 1997-05-30 | 1999-11-30 | Upjohn Co | Antibakteerisia oksatosolidinoniaineita, joilla on tiokarbonyylifunktionaalisuus |
| GB9812019D0 (en) * | 1998-06-05 | 1998-07-29 | Zeneca Ltd | Chemical compounds |
-
2000
- 2000-11-15 PE PE2000001220A patent/PE20010851A1/es not_active Application Discontinuation
- 2000-11-20 AR ARP000106119A patent/AR026547A1/es unknown
- 2000-11-24 TW TW089125030A patent/TW544449B/zh not_active IP Right Cessation
- 2000-12-06 CA CA002387047A patent/CA2387047A1/en not_active Abandoned
- 2000-12-06 DE DE60017941T patent/DE60017941T2/de not_active Expired - Fee Related
- 2000-12-06 AU AU18058/01A patent/AU1805801A/en not_active Abandoned
- 2000-12-06 HU HU0203787A patent/HUP0203787A3/hu unknown
- 2000-12-06 IL IL15003100A patent/IL150031A0/xx unknown
- 2000-12-06 MX MXPA02005909A patent/MXPA02005909A/es not_active Application Discontinuation
- 2000-12-06 ES ES00980849T patent/ES2236006T3/es not_active Expired - Lifetime
- 2000-12-06 JP JP2001544702A patent/JP2003516977A/ja active Pending
- 2000-12-06 US US09/732,088 patent/US6281210B1/en not_active Expired - Fee Related
- 2000-12-06 KR KR1020027007514A patent/KR20020062332A/ko not_active Withdrawn
- 2000-12-06 BR BR0015177-7A patent/BR0015177A/pt not_active IP Right Cessation
- 2000-12-06 WO PCT/US2000/032432 patent/WO2001044212A1/en not_active Ceased
- 2000-12-06 EA EA200200673A patent/EA200200673A1/ru unknown
- 2000-12-06 EP EP00980849A patent/EP1242395B1/de not_active Expired - Lifetime
- 2000-12-06 PT PT00980849T patent/PT1242395E/pt unknown
- 2000-12-06 PL PL00355369A patent/PL355369A1/xx not_active Application Discontinuation
- 2000-12-06 CZ CZ20022389A patent/CZ20022389A3/cs unknown
- 2000-12-06 AT AT00980849T patent/ATE288423T1/de not_active IP Right Cessation
- 2000-12-06 SK SK597-2002A patent/SK5972002A3/sk unknown
- 2000-12-06 CN CN00815710A patent/CN1390211A/zh active Pending
- 2000-12-12 CO CO00094338A patent/CO5261527A1/es not_active Application Discontinuation
-
2002
- 2002-04-15 ZA ZA200202953A patent/ZA200202953B/xx unknown
- 2002-06-13 NO NO20022811A patent/NO20022811L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| AU1805801A (en) | 2001-06-25 |
| AR026547A1 (es) | 2003-02-19 |
| ES2236006T3 (es) | 2005-07-16 |
| PE20010851A1 (es) | 2001-08-17 |
| WO2001044212A1 (en) | 2001-06-21 |
| EP1242395A1 (de) | 2002-09-25 |
| US6281210B1 (en) | 2001-08-28 |
| IL150031A0 (en) | 2002-12-01 |
| SK5972002A3 (en) | 2003-01-09 |
| CO5261527A1 (es) | 2003-03-31 |
| KR20020062332A (ko) | 2002-07-25 |
| PL355369A1 (en) | 2004-04-19 |
| MXPA02005909A (es) | 2002-10-23 |
| CZ20022389A3 (cs) | 2002-10-16 |
| CA2387047A1 (en) | 2001-06-21 |
| TW544449B (en) | 2003-08-01 |
| BR0015177A (pt) | 2002-06-18 |
| DE60017941D1 (de) | 2005-03-10 |
| CN1390211A (zh) | 2003-01-08 |
| NO20022811D0 (no) | 2002-06-13 |
| NO20022811L (no) | 2002-06-13 |
| PT1242395E (pt) | 2005-05-31 |
| EP1242395B1 (de) | 2005-02-02 |
| HUP0203787A2 (hu) | 2003-07-28 |
| HUP0203787A3 (en) | 2005-06-28 |
| EA200200673A1 (ru) | 2002-12-26 |
| DE60017941T2 (de) | 2006-03-30 |
| JP2003516977A (ja) | 2003-05-20 |
| ZA200202953B (en) | 2003-09-23 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
Ref document number: 1242395 Country of ref document: EP |
|
| REN | Ceased due to non-payment of the annual fee |