ATE288441T1 - Beta-ketophosphonaten - Google Patents

Beta-ketophosphonaten

Info

Publication number: ATE288441T1
Authority: AT; Austria
Prior art keywords: ketophosphonates; followed; beta; reaction; purification
Prior art date: 2001-09-27

Application number

AT02755252T

Other languages

English (en)

Inventor

Christopher John Harris

Alan Craig Smith

Julie Ann Salter

Original Assignee

Rhodia Cons Spec Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-09-27

Filing date

2002-08-23

Publication date

2005-02-15

2002-08-23 Application filed by Rhodia Cons Spec Ltd filed Critical Rhodia Cons Spec Ltd

2005-02-15 Application granted granted Critical

2005-02-15 Publication of ATE288441T1 publication Critical patent/ATE288441T1/de

Links

238000006243 chemical reaction Methods 0.000 abstract 2
238000000746 purification Methods 0.000 abstract 2
239000002904 solvent Substances 0.000 abstract 2
WETWJCDKMRHUPV-UHFFFAOYSA-N acetyl chloride Chemical compound CC(Cl)=O WETWJCDKMRHUPV-UHFFFAOYSA-N 0.000 abstract 1
239000012346 acetyl chloride Substances 0.000 abstract 1
150000001266 acyl halides Chemical class 0.000 abstract 1
150000004945 aromatic hydrocarbons Chemical class 0.000 abstract 1
230000015572 biosynthetic process Effects 0.000 abstract 1
MVPPADPHJFYWMZ-UHFFFAOYSA-N chlorobenzene Chemical compound ClC1=CC=CC=C1 MVPPADPHJFYWMZ-UHFFFAOYSA-N 0.000 abstract 1
238000006114 decarboxylation reaction Methods 0.000 abstract 1
150000002148 esters Chemical class 0.000 abstract 1
238000000034 method Methods 0.000 abstract 1
ZJAOAACCNHFJAH-UHFFFAOYSA-N phosphonoformic acid Chemical compound OC(=O)P(O)(O)=O ZJAOAACCNHFJAH-UHFFFAOYSA-N 0.000 abstract 1
239000011541 reaction mixture Substances 0.000 abstract 1
GGUBFICZYGKNTD-UHFFFAOYSA-N triethyl phosphonoacetate Chemical compound CCOC(=O)CP(=O)(OCC)OCC GGUBFICZYGKNTD-UHFFFAOYSA-N 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
- C07F9/40—Esters thereof
- C07F9/4003—Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
- C07F9/4056—Esters of arylalkanephosphonic acids
- C07F9/4059—Compounds containing the structure (RY)2P(=X)-(CH2)n-C(=O)-(CH2)m-Ar, (X, Y = O, S, Se; n>=1, m>=0)
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
- C07F9/40—Esters thereof
- C07F9/4003—Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
- C07F9/4006—Esters of acyclic acids which can have further substituents on alkyl

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Biochemistry (AREA)
General Health & Medical Sciences (AREA)
Molecular Biology (AREA)
Crystallography & Structural Chemistry (AREA)
Saccharide Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

AT02755252T 2001-09-27 2002-08-23 Beta-ketophosphonaten ATE288441T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GBGB0123202.4A GB0123202D0 (en)	2001-09-27	2001-09-27	Beta-ketophosphonates
PCT/GB2002/003922 WO2003027129A1 (en)	2001-09-27	2002-08-23	Beta-ketophosphonates

Publications (1)

Publication Number	Publication Date
ATE288441T1 true ATE288441T1 (de)	2005-02-15

Family

ID=9922770

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT02755252T ATE288441T1 (de)	2001-09-27	2002-08-23	Beta-ketophosphonaten

Country Status (9)

Country	Link
US (1)	US7112692B2 (de)
EP (1)	EP1430065B1 (de)
JP (1)	JP4399262B2 (de)
AT (1)	ATE288441T1 (de)
CA (1)	CA2463287C (de)
DE (1)	DE60202884T2 (de)
ES (1)	ES2236554T3 (de)
GB (1)	GB0123202D0 (de)
WO (1)	WO2003027129A1 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US7235688B1 (en)	2004-11-04	2007-06-26	University Of Notre Dame Du Lac	Process for preparing histone deacetylase inhibitors and intermediates thereof
US20070021612A1 (en) *	2004-11-04	2007-01-25	University Of Notre Dame Du Lac	Processes and compounds for preparing histone deacetylase inhibitors and intermediates thereof
CN104341449A (zh) *	2014-09-30	2015-02-11	苏州大学	一种β-羰基膦酸酯衍生物的制备方法
CN105330690B (zh) *	2015-10-19	2017-03-29	深圳瑞科生物科技有限公司	一种药物中间体芳基酮膦酸酯化合物的合成方法

2001
- 2001-09-27 GB GBGB0123202.4A patent/GB0123202D0/en not_active Ceased
2002
- 2002-08-23 US US10/485,899 patent/US7112692B2/en not_active Expired - Lifetime
- 2002-08-23 DE DE60202884T patent/DE60202884T2/de not_active Expired - Lifetime
- 2002-08-23 AT AT02755252T patent/ATE288441T1/de not_active IP Right Cessation
- 2002-08-23 CA CA002463287A patent/CA2463287C/en not_active Expired - Fee Related
- 2002-08-23 JP JP2003530716A patent/JP4399262B2/ja not_active Expired - Fee Related
- 2002-08-23 EP EP02755252A patent/EP1430065B1/de not_active Expired - Lifetime
- 2002-08-23 WO PCT/GB2002/003922 patent/WO2003027129A1/en not_active Ceased
- 2002-08-23 ES ES02755252T patent/ES2236554T3/es not_active Expired - Lifetime

Also Published As

Publication number	Publication date
EP1430065A1 (de)	2004-06-23
WO2003027129A1 (en)	2003-04-03
CA2463287C (en)	2009-12-15
US20040267040A1 (en)	2004-12-30
DE60202884T2 (de)	2005-10-27
EP1430065B1 (de)	2005-02-02
CA2463287A1 (en)	2003-04-03
GB0123202D0 (en)	2001-11-21
JP4399262B2 (ja)	2010-01-13
JP2005503443A (ja)	2005-02-03
DE60202884D1 (de)	2005-03-10
US7112692B2 (en)	2006-09-26
ES2236554T3 (es)	2005-07-16

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Legal Events

Date	Code	Title	Description
2005-08-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties