ATE289194T1 - Eindämmung der wiederaufnahme von drogenmissbrauch - Google Patents

Eindämmung der wiederaufnahme von drogenmissbrauch

Info

Publication number: ATE289194T1
Authority: AT; Austria
Prior art keywords: resumption; reducing; drug abuse; receptor agonists; adrenergic receptor
Prior art date: 2000-02-28

Application number

AT01909964T

Other languages

English (en)

Inventor

Keith Davies

Dzung Anh Le

Original Assignee

Britannia Pharmaceuticals Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-02-28

Filing date

2001-02-28

Publication date

2005-03-15

2001-02-28 Application filed by Britannia Pharmaceuticals Ltd filed Critical Britannia Pharmaceuticals Ltd

2005-03-15 Application granted granted Critical

2005-03-15 Publication of ATE289194T1 publication Critical patent/ATE289194T1/de

Links

206010013654 Drug abuse Diseases 0.000 title 1
208000011117 substance-related disease Diseases 0.000 title 1
LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 2
239000000048 adrenergic agonist Substances 0.000 abstract 2
229940126157 adrenergic receptor agonist Drugs 0.000 abstract 2
SNICXCGAKADSCV-JTQLQIEISA-N (-)-Nicotine Chemical compound CN1CCC[C@H]1C1=CC=CN=C1 SNICXCGAKADSCV-JTQLQIEISA-N 0.000 abstract 1
GJSURZIOUXUGAL-UHFFFAOYSA-N Clonidine Chemical compound ClC1=CC=CC(Cl)=C1NC1=NCCN1 GJSURZIOUXUGAL-UHFFFAOYSA-N 0.000 abstract 1
WDZVGELJXXEGPV-YIXHJXPBSA-N Guanabenz Chemical compound NC(N)=N\N=C\C1=C(Cl)C=CC=C1Cl WDZVGELJXXEGPV-YIXHJXPBSA-N 0.000 abstract 1
102000030484 alpha-2 Adrenergic Receptor Human genes 0.000 abstract 1
108020004101 alpha-2 Adrenergic Receptor Proteins 0.000 abstract 1
229960002896 clonidine Drugs 0.000 abstract 1
229940079593 drug Drugs 0.000 abstract 1
239000003814 drug Substances 0.000 abstract 1
229960004553 guanabenz Drugs 0.000 abstract 1
KSMAGQUYOIHWFS-UHFFFAOYSA-N lofexidine Chemical compound N=1CCNC=1C(C)OC1=C(Cl)C=CC=C1Cl KSMAGQUYOIHWFS-UHFFFAOYSA-N 0.000 abstract 1
229960005209 lofexidine Drugs 0.000 abstract 1
239000000463 material Substances 0.000 abstract 1
229960002715 nicotine Drugs 0.000 abstract 1
SNICXCGAKADSCV-UHFFFAOYSA-N nicotine Natural products CN1CCCC1C1=CC=CN=C1 SNICXCGAKADSCV-UHFFFAOYSA-N 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4168—1,3-Diazoles having a nitrogen attached in position 2, e.g. clonidine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Epidemiology (AREA)
Engineering & Computer Science (AREA)
Chemical Kinetics & Catalysis (AREA)
Addiction (AREA)
Bioinformatics & Cheminformatics (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Psychiatry (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Hydrogenated Pyridines (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Medicines Containing Plant Substances (AREA)

AT01909964T 2000-02-28 2001-02-28 Eindämmung der wiederaufnahme von drogenmissbrauch ATE289194T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GBGB0004708.4A GB0004708D0 (en)	2000-02-28	2000-02-28	Restricting reinstatement of drug use
PCT/GB2001/000847 WO2001064201A2 (en)	2000-02-28	2001-02-28	Restricting reinstatement of drug use

Publications (1)

Publication Number	Publication Date
ATE289194T1 true ATE289194T1 (de)	2005-03-15

Family

ID=9886566

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT01909964T ATE289194T1 (de)	2000-02-28	2001-02-28	Eindämmung der wiederaufnahme von drogenmissbrauch

Country Status (8)

Country	Link
US (1)	US20040077636A1 (de)
EP (1)	EP1267849B1 (de)
AT (1)	ATE289194T1 (de)
AU (1)	AU2001237550A1 (de)
DE (1)	DE60108947T2 (de)
ES (1)	ES2236183T3 (de)
GB (2)	GB0004708D0 (de)
WO (1)	WO2001064201A2 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
SE521512C2 (sv)	2001-06-25	2003-11-11	Niconovum Ab	Anordning för administrering av en substans till främre delen av en individs munhåla
WO2003063528A2 (en)	2002-01-16	2003-07-31	Sure On Sight Ltd	Secure messaging via a mobile communications network
ES2285233T3 (es)	2002-12-20	2007-11-16	Niconovum Ab	Un material en particulas que contiene nicotina y celulosa microcristalina fisicamente y quimicamente estable.
EP1749525A1 (de) *	2005-07-15	2007-02-07	Laboratorios Del Dr. Esteve, S.A.	Zusammensetzung enthaltend substituierte Pyrazoline und gegen Sucht wirksame Mittel
ES2319074B1 (es) *	2005-07-15	2009-12-03	Laboratorios Del Dr. Esteve, S.A.	Combinacion de principios activos.
US9402809B2 (en)	2006-03-16	2016-08-02	Niconovum Usa, Inc.	Snuff composition
US20090246256A1 (en) *	2008-03-27	2009-10-01	Al-Ghananeem Abeer M	Compositions and Methods for Transmucosal Delivery of Lofexidine

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4800209A (en) *	1981-12-14	1989-01-24	Merrell Dow Pharmaceuticals Inc.	Method of alleviating withdrawal symptoms
US4382946A (en) *	1981-12-14	1983-05-10	Merrell Dow Pharmaceuticals Inc.	Method of alleviating withdrawal symptoms
US4783456A (en) *	1984-03-02	1988-11-08	Research Foundation For Mental Hygiene, Inc.	Method of preventing withdrawal symptoms associated with the cessation or reduction of tobacco smoking
US4788189A (en) *	1988-02-29	1988-11-29	Glazer Howard I	Method to treat smoking withdrawal symptoms by potentiated central noradrenergic blocking
PT99629A (pt) *	1991-11-28	1993-05-31	Antonio Feria Reis Valle	Metodo de desintoxicacao de opiaceos
US5272149A (en) *	1992-05-05	1993-12-21	Stalling Reginald W	Symptom controlled receptor substitution for addiction withdrawl
WO1996014071A1 (es) *	1994-11-04	1996-05-17	Legarda Ibanez Juan Jose	Combinacion de farmacos como medicamento destinado a supresion de dependencia de individuos a opiaceos
US5789411A (en) *	1995-09-11	1998-08-04	Lance L. Gooberman P. C.	Improvements to rapid opioid detoxification

2000
- 2000-02-28 GB GBGB0004708.4A patent/GB0004708D0/en not_active Ceased
- 2000-02-28 GB GB0111220A patent/GB2359488A/en not_active Withdrawn
2001
- 2001-02-28 DE DE60108947T patent/DE60108947T2/de not_active Expired - Lifetime
- 2001-02-28 AU AU2001237550A patent/AU2001237550A1/en not_active Abandoned
- 2001-02-28 US US10/204,788 patent/US20040077636A1/en not_active Abandoned
- 2001-02-28 EP EP01909964A patent/EP1267849B1/de not_active Expired - Lifetime
- 2001-02-28 AT AT01909964T patent/ATE289194T1/de active
- 2001-02-28 ES ES01909964T patent/ES2236183T3/es not_active Expired - Lifetime
- 2001-02-28 WO PCT/GB2001/000847 patent/WO2001064201A2/en not_active Ceased

Also Published As

Publication number	Publication date
ES2236183T3 (es)	2005-07-16
GB0004708D0 (en)	2000-04-19
EP1267849A2 (de)	2003-01-02
DE60108947T2 (de)	2005-10-27
WO2001064201A2 (en)	2001-09-07
EP1267849B1 (de)	2005-02-16
AU2001237550A1 (en)	2001-09-12
US20040077636A1 (en)	2004-04-22
GB0111220D0 (en)	2001-06-27
DE60108947D1 (de)	2005-03-24
WO2001064201A3 (en)	2002-07-18
GB2359488A (en)	2001-08-29

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2005-11-15

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