ATE289806T1 - Verfahren zur herstellung pharmazeutischer zusammensetzungen von lipidpartikeln, enthaltend einen lipidwirkstoff sowie ein protein - Google Patents

Verfahren zur herstellung pharmazeutischer zusammensetzungen von lipidpartikeln, enthaltend einen lipidwirkstoff sowie ein protein

Info

Publication number
ATE289806T1
ATE289806T1 AT98934120T AT98934120T ATE289806T1 AT E289806 T1 ATE289806 T1 AT E289806T1 AT 98934120 T AT98934120 T AT 98934120T AT 98934120 T AT98934120 T AT 98934120T AT E289806 T1 ATE289806 T1 AT E289806T1
Authority
AT
Austria
Prior art keywords
lipid
protein
active ingredient
pharmaceutical compositions
particles containing
Prior art date
Application number
AT98934120T
Other languages
English (en)
Inventor
Mattias Andersson
Dorota Johansson
Percy Li
Bjoern Norrlind
Bengt Westgren
Original Assignee
Pfizer Health Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Health Ab filed Critical Pfizer Health Ab
Application granted granted Critical
Publication of ATE289806T1 publication Critical patent/ATE289806T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5107—Excipients; Inactive ingredients
    • A61K9/5123—Organic compounds, e.g. fats, sugars
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1275—Lipoproteins or protein-free species thereof, e.g. chylomicrons; Artificial high-density lipoproteins [HDL], low-density lipoproteins [LDL] or very-low-density lipoproteins [VLDL]; Precursors thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Optics & Photonics (AREA)
  • Nanotechnology (AREA)
  • Biomedical Technology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Dispersion Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT98934120T 1997-07-22 1998-07-22 Verfahren zur herstellung pharmazeutischer zusammensetzungen von lipidpartikeln, enthaltend einen lipidwirkstoff sowie ein protein ATE289806T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE9702776A SE9702776D0 (sv) 1997-07-22 1997-07-22 Method of preparing pharmaceutical compositions
PCT/SE1998/001407 WO1999004761A1 (en) 1997-07-22 1998-07-22 Method of preparing pharmaceutical compositions of lipid particles comprising a lipid agent and a protein

Publications (1)

Publication Number Publication Date
ATE289806T1 true ATE289806T1 (de) 2005-03-15

Family

ID=20407807

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98934120T ATE289806T1 (de) 1997-07-22 1998-07-22 Verfahren zur herstellung pharmazeutischer zusammensetzungen von lipidpartikeln, enthaltend einen lipidwirkstoff sowie ein protein

Country Status (12)

Country Link
EP (1) EP1014947B1 (de)
JP (1) JP3813439B2 (de)
AT (1) ATE289806T1 (de)
AU (1) AU744738B2 (de)
CA (1) CA2297924C (de)
DE (1) DE69829191T2 (de)
ES (1) ES2236919T3 (de)
NO (1) NO20000330L (de)
NZ (1) NZ502840A (de)
PT (1) PT1014947E (de)
SE (1) SE9702776D0 (de)
WO (1) WO1999004761A1 (de)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8206749B1 (en) * 1999-02-26 2012-06-26 Novartis Vaccines And Diagnostics, Inc. Microemulsions with adsorbed macromolecules and microparticles
AU2596401A (en) * 1999-12-22 2001-07-03 Surgical Sealants, Inc. Methods and compositions for sealing tissue leaks
CZ20013523A3 (cs) * 2000-02-02 2002-03-13 Florida State University Research Foundation, Inc. Taxany s C10 heterosubstituovaným acetátem jako protinádorové látky
US6514523B1 (en) * 2000-02-14 2003-02-04 Ottawa Heart Institute Research Corporation Carrier particles for drug delivery and process for preparation
CA2407027C (en) * 2000-04-20 2011-02-15 Rtp Pharma Inc. Improved water-insoluble drug particle process
US6599441B1 (en) * 2000-07-18 2003-07-29 Emerald Biostructures, Inc. Crystallization solutions
CN101284136A (zh) 2002-12-03 2008-10-15 布朗歇特洛克菲勒神经科学研究所 传输物质穿过血脑屏障的人工低密度脂蛋白载体
US7803400B2 (en) 2002-12-03 2010-09-28 Blanchette Rockefeller Neurosciences Institute Artificial low-density lipoprotein carriers for transport of substances across the blood-brain barrier
KR100720213B1 (ko) * 2003-04-04 2007-05-21 화이자 프로덕츠 인코포레이티드 미세 유동화된 수중 유적형 유화액 및 백신 조성물
JP4050784B2 (ja) * 2005-02-03 2008-02-20 株式会社Ｎｒｌファーマ マトリックス型腸溶性・徐放性組成物
US7951396B2 (en) * 2005-03-28 2011-05-31 Regeron, Inc. Preparation of nanoliposome-encapsulating proteins and protein-encapsulated nanoliposome
US20070151853A1 (en) * 2005-12-29 2007-07-05 Invitrogen Corporation Compositions and Methods for Improving Resolution of Biomolecules Separated on Polyacrylamide Gels
EP1915986A1 (de) 2006-10-23 2008-04-30 BIOPHARM GESELLSCHAFT ZUR BIOTECHNOLOGISCHEN ENTWICKLUNG VON PHARMAKA mbH Wachstumsfaktorhaltige Lipidformulierungen
CH715456B1 (de) 2007-04-27 2020-04-30 Mibelle Ag Kosmetisches Produkt zur topischen Anwendung für den Schutz und die Erneuerung von Hautstammzellen, welches sich von dedifferenzierten Pflanzenzellen ableitet.
US8071759B2 (en) 2008-07-18 2011-12-06 Affymetrix, Inc. Water soluble cholesterol derivatives
US8734853B2 (en) 2008-11-17 2014-05-27 University Of North Texas Health Science Center At Fort Worth HDL particles for delivery of nucleic acids
JP4912510B2 (ja) * 2009-08-31 2012-04-11 ナノキャリア株式会社 粒子組成物及びこれを有する医薬組成物
US20160346221A1 (en) 2015-06-01 2016-12-01 Autotelic Llc Phospholipid-coated therapeutic agent nanoparticles and related methods
WO2025215934A1 (ja) * 2024-04-09 2025-10-16 コニカミノルタ株式会社 予測装置、予測装置の粒径分布予測方法、および粒径分布予測プログラム

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5128318A (en) * 1987-05-20 1992-07-07 The Rogosin Institute Reconstituted HDL particles and uses thereof
IL86799A (en) * 1987-07-02 1993-03-15 Kabi Pharmacia Ab Method and device for injection
US5576016A (en) * 1993-05-18 1996-11-19 Pharmos Corporation Solid fat nanoemulsions as drug delivery vehicles
US5652339A (en) * 1993-12-31 1997-07-29 Rotkreuzstiftung Zentrallaboratorium Method of producing reconstituted lipoproteins

Also Published As

Publication number Publication date
DE69829191T2 (de) 2005-07-21
EP1014947B1 (de) 2005-03-02
SE9702776D0 (sv) 1997-07-22
NO20000330D0 (no) 2000-01-21
DE69829191D1 (de) 2005-04-07
WO1999004761A1 (en) 1999-02-04
CA2297924C (en) 2007-04-10
JP2001510786A (ja) 2001-08-07
ES2236919T3 (es) 2005-07-16
AU8371898A (en) 1999-02-16
CA2297924A1 (en) 1999-02-04
PT1014947E (pt) 2005-05-31
AU744738B2 (en) 2002-02-28
NO20000330L (no) 2000-03-21
NZ502840A (en) 2002-08-28
EP1014947A1 (de) 2000-07-05
JP3813439B2 (ja) 2006-08-23

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