ATE245445T1 - Suspension enthaltend ein epi-hne protein, verfahren zu ihrer herstellung, daraus hergestelltes trockenpulveraerosol, arzneimittelzusammensetzungen enthaltend diese suspension oder dieses aerosol und ihre verwendungen - Google Patents
Suspension enthaltend ein epi-hne protein, verfahren zu ihrer herstellung, daraus hergestelltes trockenpulveraerosol, arzneimittelzusammensetzungen enthaltend diese suspension oder dieses aerosol und ihre verwendungenInfo
- Publication number
- ATE245445T1 ATE245445T1 AT01992586T AT01992586T ATE245445T1 AT E245445 T1 ATE245445 T1 AT E245445T1 AT 01992586 T AT01992586 T AT 01992586T AT 01992586 T AT01992586 T AT 01992586T AT E245445 T1 ATE245445 T1 AT E245445T1
- Authority
- AT
- Austria
- Prior art keywords
- suspension
- aerosol
- dry powder
- epi
- producing
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/0078—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/55—Protease inhibitors
- A61K38/57—Protease inhibitors from animals; from humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Pulmonology (AREA)
- Otolaryngology (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Dispersion Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP00403035A EP1201249A1 (de) | 2000-10-31 | 2000-10-31 | Suspension von EPI-HNE-4, daraus hergestelltes Trockenpulveraerosol, Herstellungsverfahren und Arzneimittel enthaltend diese Suspension- oder Aerosolzubereitung und ihre Verwendung |
| EP01401731 | 2001-06-28 | ||
| PCT/EP2001/012983 WO2002036158A1 (en) | 2000-10-31 | 2001-10-26 | Suspension of an epi-hne protein, process of preparation thereof, dry powder aerosol derived therefrom, pharmaceutical compositions containing said suspension or aerosol, and their uses |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE245445T1 true ATE245445T1 (de) | 2003-08-15 |
Family
ID=26073607
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT01992586T ATE245445T1 (de) | 2000-10-31 | 2001-10-26 | Suspension enthaltend ein epi-hne protein, verfahren zu ihrer herstellung, daraus hergestelltes trockenpulveraerosol, arzneimittelzusammensetzungen enthaltend diese suspension oder dieses aerosol und ihre verwendungen |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US6814982B2 (de) |
| EP (1) | EP1223972B1 (de) |
| JP (1) | JP2004512377A (de) |
| KR (1) | KR100826342B1 (de) |
| CN (2) | CN100396329C (de) |
| AT (1) | ATE245445T1 (de) |
| AU (2) | AU2002217014B2 (de) |
| BR (1) | BR0115020A (de) |
| CA (1) | CA2426992A1 (de) |
| DE (1) | DE60100500T2 (de) |
| DK (1) | DK1223972T3 (de) |
| ES (1) | ES2203601T3 (de) |
| HK (1) | HK1048064B (de) |
| MX (1) | MXPA03003785A (de) |
| PT (1) | PT1223972E (de) |
| WO (1) | WO2002036158A1 (de) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6057287A (en) | 1994-01-11 | 2000-05-02 | Dyax Corp. | Kallikrein-binding "Kunitz domain" proteins and analogues thereof |
| US7153829B2 (en) | 2002-06-07 | 2006-12-26 | Dyax Corp. | Kallikrein-inhibitor therapies |
| ES2348230T3 (es) * | 2002-06-07 | 2010-12-01 | Dyax Corp. | Prevención y reducción de la isquemia. |
| US20040265238A1 (en) | 2003-06-27 | 2004-12-30 | Imtiaz Chaudry | Inhalable formulations for treating pulmonary hypertension and methods of using same |
| US20050089515A1 (en) * | 2003-08-29 | 2005-04-28 | Dyax Corp. | Poly-pegylated protease inhibitors |
| US7235530B2 (en) | 2004-09-27 | 2007-06-26 | Dyax Corporation | Kallikrein inhibitors and anti-thrombolytic agents and uses thereof |
| WO2006071102A1 (en) * | 2004-12-30 | 2006-07-06 | Dobeel Co., Ltd. | Spray-dried composition containing collectin family proteins or variants therof and process for preparing the same |
| US20090075887A1 (en) * | 2007-08-21 | 2009-03-19 | Genzyme Corporation | Treatment with Kallikrein Inhibitors |
| US8637454B2 (en) | 2009-01-06 | 2014-01-28 | Dyax Corp. | Treatment of mucositis with kallikrein inhibitors |
| SMT201800552T1 (it) | 2010-01-06 | 2018-11-09 | Dyax Corp | Proteine che legano la callicreina plasmatica |
| KR102320178B1 (ko) | 2011-01-06 | 2021-11-02 | 다케다 파머수티컬 컴패니 리미티드 | 혈장 칼리크레인 결합 단백질 |
| US10428158B2 (en) | 2014-03-27 | 2019-10-01 | Dyax Corp. | Compositions and methods for treatment of diabetic macular edema |
| EP3387018A1 (de) | 2015-12-11 | 2018-10-17 | Dyax Corp. | Plasma-kallikrein-inhibitoren und verwendungen davon zur behandlung von hereditärem angioödem |
| CN110141561A (zh) * | 2018-03-29 | 2019-08-20 | 中国人民解放军军事科学院军事医学研究院 | 一种可气溶胶化蛋白干粉吸入剂的制备技术 |
| EP4090427A1 (de) | 2020-01-13 | 2022-11-23 | Takeda Pharmaceutical Company Limited | Plasma-kallikrein-inhibitoren und verwendungen davon zur pädiatrischen behandlung von hereditärem angioödem |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5663143A (en) * | 1988-09-02 | 1997-09-02 | Dyax Corp. | Engineered human-derived kunitz domains that inhibit human neutrophil elastase |
| US5148381A (en) * | 1991-02-07 | 1992-09-15 | Intel Corporation | One-dimensional interpolation circuit and method based on modification of a parallel multiplier |
| AU1581692A (en) * | 1991-03-01 | 1992-10-06 | Protein Engineering Corporation | Inhibitors of human neutrophil elastase and human cathepsin g |
| EP1184393A1 (de) | 2000-09-04 | 2002-03-06 | Debiopharm S.A. | Verfahren zur Reinigung von EPI-HNE Proteinen |
-
2001
- 2001-10-26 CN CNB01818118XA patent/CN100396329C/zh not_active Expired - Fee Related
- 2001-10-26 CN CNB2004100856047A patent/CN1287856C/zh not_active Expired - Fee Related
- 2001-10-26 JP JP2002538967A patent/JP2004512377A/ja active Pending
- 2001-10-26 MX MXPA03003785A patent/MXPA03003785A/es active IP Right Grant
- 2001-10-26 ES ES01992586T patent/ES2203601T3/es not_active Expired - Lifetime
- 2001-10-26 DE DE60100500T patent/DE60100500T2/de not_active Expired - Lifetime
- 2001-10-26 EP EP01992586A patent/EP1223972B1/de not_active Expired - Lifetime
- 2001-10-26 AU AU2002217014A patent/AU2002217014B2/en not_active Ceased
- 2001-10-26 CA CA002426992A patent/CA2426992A1/en not_active Abandoned
- 2001-10-26 DK DK01992586T patent/DK1223972T3/da active
- 2001-10-26 PT PT01992586T patent/PT1223972E/pt unknown
- 2001-10-26 AT AT01992586T patent/ATE245445T1/de not_active IP Right Cessation
- 2001-10-26 KR KR1020037005928A patent/KR100826342B1/ko not_active Expired - Fee Related
- 2001-10-26 WO PCT/EP2001/012983 patent/WO2002036158A1/en not_active Ceased
- 2001-10-26 AU AU1701402A patent/AU1701402A/xx active Pending
- 2001-10-26 HK HK03100036.3A patent/HK1048064B/en not_active IP Right Cessation
- 2001-10-26 BR BR0115020-0A patent/BR0115020A/pt not_active IP Right Cessation
-
2003
- 2003-04-17 US US10/417,854 patent/US6814982B2/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| CN1287856C (zh) | 2006-12-06 |
| EP1223972A1 (de) | 2002-07-24 |
| ES2203601T3 (es) | 2004-04-16 |
| US6814982B2 (en) | 2004-11-09 |
| PT1223972E (pt) | 2003-11-28 |
| WO2002036158A8 (en) | 2004-03-04 |
| CN1636595A (zh) | 2005-07-13 |
| WO2002036158A1 (en) | 2002-05-10 |
| HK1048064B (en) | 2004-02-13 |
| BR0115020A (pt) | 2003-12-23 |
| HK1048064A1 (en) | 2003-03-21 |
| DE60100500D1 (de) | 2003-08-28 |
| AU1701402A (en) | 2002-05-15 |
| CN100396329C (zh) | 2008-06-25 |
| EP1223972B1 (de) | 2003-07-23 |
| CN1471405A (zh) | 2004-01-28 |
| AU2002217014B2 (en) | 2006-11-02 |
| KR20030059809A (ko) | 2003-07-10 |
| MXPA03003785A (es) | 2004-04-20 |
| JP2004512377A (ja) | 2004-04-22 |
| DE60100500T2 (de) | 2004-04-15 |
| KR100826342B1 (ko) | 2008-05-02 |
| US20040013659A1 (en) | 2004-01-22 |
| DK1223972T3 (da) | 2003-11-03 |
| CA2426992A1 (en) | 2002-05-10 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
Ref document number: 1223972 Country of ref document: EP |
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| REN | Ceased due to non-payment of the annual fee |