ATE245445T1 - Suspension enthaltend ein epi-hne protein, verfahren zu ihrer herstellung, daraus hergestelltes trockenpulveraerosol, arzneimittelzusammensetzungen enthaltend diese suspension oder dieses aerosol und ihre verwendungen - Google Patents
Suspension enthaltend ein epi-hne protein, verfahren zu ihrer herstellung, daraus hergestelltes trockenpulveraerosol, arzneimittelzusammensetzungen enthaltend diese suspension oder dieses aerosol und ihre verwendungenInfo
- Publication number
- ATE245445T1 ATE245445T1 AT01992586T AT01992586T ATE245445T1 AT E245445 T1 ATE245445 T1 AT E245445T1 AT 01992586 T AT01992586 T AT 01992586T AT 01992586 T AT01992586 T AT 01992586T AT E245445 T1 ATE245445 T1 AT E245445T1
- Authority
- AT
- Austria
- Prior art keywords
- suspension
- aerosol
- dry powder
- epi
- producing
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/0078—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/55—Protease inhibitors
- A61K38/57—Protease inhibitors from animals; from humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Pulmonology (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Dispersion Chemistry (AREA)
- Otolaryngology (AREA)
- Zoology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP00403035A EP1201249A1 (de) | 2000-10-31 | 2000-10-31 | Suspension von EPI-HNE-4, daraus hergestelltes Trockenpulveraerosol, Herstellungsverfahren und Arzneimittel enthaltend diese Suspension- oder Aerosolzubereitung und ihre Verwendung |
| EP01401731 | 2001-06-28 | ||
| PCT/EP2001/012983 WO2002036158A1 (en) | 2000-10-31 | 2001-10-26 | Suspension of an epi-hne protein, process of preparation thereof, dry powder aerosol derived therefrom, pharmaceutical compositions containing said suspension or aerosol, and their uses |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE245445T1 true ATE245445T1 (de) | 2003-08-15 |
Family
ID=26073607
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT01992586T ATE245445T1 (de) | 2000-10-31 | 2001-10-26 | Suspension enthaltend ein epi-hne protein, verfahren zu ihrer herstellung, daraus hergestelltes trockenpulveraerosol, arzneimittelzusammensetzungen enthaltend diese suspension oder dieses aerosol und ihre verwendungen |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US6814982B2 (de) |
| EP (1) | EP1223972B1 (de) |
| JP (1) | JP2004512377A (de) |
| KR (1) | KR100826342B1 (de) |
| CN (2) | CN100396329C (de) |
| AT (1) | ATE245445T1 (de) |
| AU (2) | AU1701402A (de) |
| BR (1) | BR0115020A (de) |
| CA (1) | CA2426992A1 (de) |
| DE (1) | DE60100500T2 (de) |
| DK (1) | DK1223972T3 (de) |
| ES (1) | ES2203601T3 (de) |
| HK (1) | HK1048064B (de) |
| MX (1) | MXPA03003785A (de) |
| PT (1) | PT1223972E (de) |
| WO (1) | WO2002036158A1 (de) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6057287A (en) | 1994-01-11 | 2000-05-02 | Dyax Corp. | Kallikrein-binding "Kunitz domain" proteins and analogues thereof |
| DK2311432T3 (en) | 2002-06-07 | 2015-02-02 | Dyax Corp | Modified Kunitz domain polypeptides and their use in reducing ischemia or the onset of a systemic inflammatory response associated with a surgical procedure |
| US7153829B2 (en) | 2002-06-07 | 2006-12-26 | Dyax Corp. | Kallikrein-inhibitor therapies |
| US20040265238A1 (en) | 2003-06-27 | 2004-12-30 | Imtiaz Chaudry | Inhalable formulations for treating pulmonary hypertension and methods of using same |
| AU2004268145B2 (en) * | 2003-08-29 | 2010-09-16 | Takeda Pharmaceutical Company Limited | Poly-PEGylated protease inhibitors |
| US7235530B2 (en) | 2004-09-27 | 2007-06-26 | Dyax Corporation | Kallikrein inhibitors and anti-thrombolytic agents and uses thereof |
| CN101094651B (zh) * | 2004-12-30 | 2011-03-09 | 多贝尔有限公司 | 含有胶原凝集素家族蛋白质或者其变体的喷雾干燥的组合物和其制备方法 |
| WO2009026334A2 (en) * | 2007-08-21 | 2009-02-26 | Genzyme Corporation | Treatment with kallikrein inhibitors |
| US8637454B2 (en) | 2009-01-06 | 2014-01-28 | Dyax Corp. | Treatment of mucositis with kallikrein inhibitors |
| ES2688093T3 (es) | 2010-01-06 | 2018-10-30 | Dyax Corp. | Proteínas de unión a calicreína plasmática |
| IL269565B2 (en) | 2011-01-06 | 2024-06-01 | Dyax Corp | Plasma kallikrein binding proteins |
| EP3122782A4 (de) | 2014-03-27 | 2017-09-13 | Dyax Corp. | Zusammensetzungen und verfahren zur behandlung von diabetischem makulaödem |
| BR112018011622A2 (pt) | 2015-12-11 | 2018-11-27 | Dyax Corp | método para tratar ataque de angioedema hereditário (hae) ou reduzir a taxa de ataque de hae |
| CN110141561A (zh) * | 2018-03-29 | 2019-08-20 | 中国人民解放军军事科学院军事医学研究院 | 一种可气溶胶化蛋白干粉吸入剂的制备技术 |
| CA3167336A1 (en) | 2020-01-13 | 2021-07-22 | Takeda Pharmaceutical Company Limited | Plasma kallikrein inhibitors and uses thereof for treating pediatric hereditary angioedema attack |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1992015605A2 (en) * | 1991-03-01 | 1992-09-17 | Protein Engineering Corporation | Inhibitors of human neutrophil elastase and human cathepsin g |
| US5663143A (en) * | 1988-09-02 | 1997-09-02 | Dyax Corp. | Engineered human-derived kunitz domains that inhibit human neutrophil elastase |
| US5148381A (en) * | 1991-02-07 | 1992-09-15 | Intel Corporation | One-dimensional interpolation circuit and method based on modification of a parallel multiplier |
| EP1184393A1 (de) | 2000-09-04 | 2002-03-06 | Debiopharm S.A. | Verfahren zur Reinigung von EPI-HNE Proteinen |
-
2001
- 2001-10-26 WO PCT/EP2001/012983 patent/WO2002036158A1/en not_active Ceased
- 2001-10-26 AU AU1701402A patent/AU1701402A/xx active Pending
- 2001-10-26 MX MXPA03003785A patent/MXPA03003785A/es active IP Right Grant
- 2001-10-26 AU AU2002217014A patent/AU2002217014B2/en not_active Ceased
- 2001-10-26 EP EP01992586A patent/EP1223972B1/de not_active Expired - Lifetime
- 2001-10-26 KR KR1020037005928A patent/KR100826342B1/ko not_active Expired - Fee Related
- 2001-10-26 ES ES01992586T patent/ES2203601T3/es not_active Expired - Lifetime
- 2001-10-26 CA CA002426992A patent/CA2426992A1/en not_active Abandoned
- 2001-10-26 CN CNB01818118XA patent/CN100396329C/zh not_active Expired - Fee Related
- 2001-10-26 JP JP2002538967A patent/JP2004512377A/ja active Pending
- 2001-10-26 HK HK03100036.3A patent/HK1048064B/en not_active IP Right Cessation
- 2001-10-26 CN CNB2004100856047A patent/CN1287856C/zh not_active Expired - Fee Related
- 2001-10-26 BR BR0115020-0A patent/BR0115020A/pt not_active IP Right Cessation
- 2001-10-26 AT AT01992586T patent/ATE245445T1/de not_active IP Right Cessation
- 2001-10-26 PT PT01992586T patent/PT1223972E/pt unknown
- 2001-10-26 DK DK01992586T patent/DK1223972T3/da active
- 2001-10-26 DE DE60100500T patent/DE60100500T2/de not_active Expired - Lifetime
-
2003
- 2003-04-17 US US10/417,854 patent/US6814982B2/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| HK1048064B (en) | 2004-02-13 |
| BR0115020A (pt) | 2003-12-23 |
| KR100826342B1 (ko) | 2008-05-02 |
| WO2002036158A1 (en) | 2002-05-10 |
| CN1287856C (zh) | 2006-12-06 |
| WO2002036158A8 (en) | 2004-03-04 |
| CN1636595A (zh) | 2005-07-13 |
| HK1048064A1 (en) | 2003-03-21 |
| JP2004512377A (ja) | 2004-04-22 |
| CA2426992A1 (en) | 2002-05-10 |
| DE60100500T2 (de) | 2004-04-15 |
| KR20030059809A (ko) | 2003-07-10 |
| AU1701402A (en) | 2002-05-15 |
| ES2203601T3 (es) | 2004-04-16 |
| AU2002217014B2 (en) | 2006-11-02 |
| CN100396329C (zh) | 2008-06-25 |
| MXPA03003785A (es) | 2004-04-20 |
| EP1223972B1 (de) | 2003-07-23 |
| EP1223972A1 (de) | 2002-07-24 |
| CN1471405A (zh) | 2004-01-28 |
| DK1223972T3 (da) | 2003-11-03 |
| US6814982B2 (en) | 2004-11-09 |
| DE60100500D1 (de) | 2003-08-28 |
| PT1223972E (pt) | 2003-11-28 |
| US20040013659A1 (en) | 2004-01-22 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
Ref document number: 1223972 Country of ref document: EP |
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| REN | Ceased due to non-payment of the annual fee |