ATE290096T1 - Coenzym zur herstellung von l-carnitin - Google Patents

Coenzym zur herstellung von l-carnitin

Info

Publication number
ATE290096T1
ATE290096T1 AT99954351T AT99954351T ATE290096T1 AT E290096 T1 ATE290096 T1 AT E290096T1 AT 99954351 T AT99954351 T AT 99954351T AT 99954351 T AT99954351 T AT 99954351T AT E290096 T1 ATE290096 T1 AT E290096T1
Authority
AT
Austria
Prior art keywords
carnitine
coenzyme
production
butyrobetainyl
crotonobetaine
Prior art date
Application number
AT99954351T
Other languages
English (en)
Inventor
Thomas Elssner
Hans-Peter Kleber
Original Assignee
Sigma Tau Ind Farmaceuti
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE1998150433 external-priority patent/DE19850433A1/de
Priority claimed from DE1998150426 external-priority patent/DE19850426A1/de
Application filed by Sigma Tau Ind Farmaceuti filed Critical Sigma Tau Ind Farmaceuti
Application granted granted Critical
Publication of ATE290096T1 publication Critical patent/ATE290096T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • C07H19/20—Purine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/007—Carnitine; Butyrobetaine; Crotonobetaine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
    • C12P41/001—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by metabolizing one of the enantiomers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • Molecular Biology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Compounds Of Unknown Constitution (AREA)
AT99954351T 1998-10-27 1999-10-22 Coenzym zur herstellung von l-carnitin ATE290096T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE1998150433 DE19850433A1 (de) 1998-10-27 1998-10-27 Crotonobetainyl-Coenzym A, Verfahren zu seiner Herstellung
DE1998150426 DE19850426A1 (de) 1998-10-27 1998-10-27 gamma-Butyrobetainyl-Coenzym A und Verfahren zu seiner Herstellung
PCT/IT1999/000339 WO2000024919A1 (en) 1998-10-27 1999-10-22 Coenzymes useful for the synthesis of l-carnitine

Publications (1)

Publication Number Publication Date
ATE290096T1 true ATE290096T1 (de) 2005-03-15

Family

ID=26049898

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99954351T ATE290096T1 (de) 1998-10-27 1999-10-22 Coenzym zur herstellung von l-carnitin

Country Status (11)

Country Link
US (2) US6379936B1 (de)
EP (2) EP1151130B1 (de)
JP (1) JP2002528468A (de)
AT (1) ATE290096T1 (de)
AU (1) AU1075400A (de)
DE (1) DE69924026T2 (de)
DK (1) DK1151130T3 (de)
ES (1) ES2237954T3 (de)
PT (1) PT1151130E (de)
SI (1) SI1151130T1 (de)
WO (1) WO2000024919A1 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030162241A1 (en) * 2000-04-17 2003-08-28 Fritz Pittner Method for determining the concentration of carnitine in fluids
US7407778B2 (en) * 2002-02-07 2008-08-05 Pettegrew Jay W Compounds, compositions and methods for treating neuropsychiatric disorders
US7700074B2 (en) * 2002-02-07 2010-04-20 Pettegrew Jay W Method and system for diagnosis of neuropsychiatric disorders including chronic alcoholism
US20060257842A1 (en) * 2003-05-29 2006-11-16 Pettegrew Jay W Cryopreservation media and molecules
DE602004022301D1 (de) * 2003-05-29 2009-09-10 Jay W Pettegrew Glycerophosphocholin und derivate davon zur medizinischen abbildung von neuropsychiatrischen erkrankungen
US20050232911A1 (en) * 2004-04-19 2005-10-20 Schreiber Brian D Prevention and treatment of metabolic abnormalities associated with excess intramyocellular lipid
KR100713104B1 (ko) * 2005-07-07 2007-05-02 씨제이 주식회사 뉴로스포라 크라사 유래의ｓ-아데노실메티오닌-6-ｎ-라이신-메틸트란스퍼라제, 그를코딩하는 폴리뉴클레오티드, 상기 폴리뉴클레오티드를포함하는 벡터 및 숙주세포 및 상기 숙주세포를 이용하여트리메틸라이신을 생산하는 방법

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1142201B (it) 1980-06-24 1986-10-08 Sigma Tau Ind Farmaceuti Procedimento per la produzione enzimatica di l-carnitina
DD221905B1 (de) 1983-11-03 1987-03-18 Univ Leipzig Verfahren zur herstellung von l(-)-carnitin und seinen derivaten
EP0320460B1 (de) 1987-10-26 1994-04-27 Sigma-Tau Industrie Farmaceutiche Riunite S.p.A. Verfahren zur Isolierung des Enzyms Karnitin-Hydrolyase von zur Familie der Enterobakteriaceae gehörenden Stämmen und Verwendung des immobilisierten Enzyms zur Herstellung von L(-)Karnitin
IT1240833B (it) 1990-05-14 1993-12-17 Sigma Tau Ind Farmaceuti Procedimento biocatalitico per la produzione di l-(-)- carnitina da crotonilbetaina e ceppi di proteeae per l'uso in tale procedimento
ATE257515T1 (de) * 1993-10-08 2004-01-15 Lonza Ag Gene für den butyrobetain/crotonobetain-l- carnitin-stoffwechsel und ihre verwendung zur mikrobiologischen herstellung von l-carnitin
FR2715167B1 (fr) * 1994-01-20 1996-04-12 Inst Nat Sciences Appliq Lyon Procédé de production de la L-carnitine par voie microbiologique.
DE4402127A1 (de) * 1994-01-21 1995-07-27 Univ Leipzig Carnitinracemase und Verfahren zu ihrer Herstellung

Also Published As

Publication number Publication date
EP1452604A3 (de) 2005-03-30
DK1151130T3 (da) 2005-06-20
JP2002528468A (ja) 2002-09-03
US20020146787A1 (en) 2002-10-10
EP1151130B1 (de) 2005-03-02
AU1075400A (en) 2000-05-15
SI1151130T1 (en) 2005-06-30
DE69924026D1 (de) 2005-04-07
US6379936B1 (en) 2002-04-30
WO2000024919A1 (en) 2000-05-04
EP1151130A1 (de) 2001-11-07
EP1452604A2 (de) 2004-09-01
US6562608B2 (en) 2003-05-13
DE69924026T2 (de) 2006-02-09
PT1151130E (pt) 2005-06-30
ES2237954T3 (es) 2005-08-01

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