ATE290606T1 - Bestimmung der länge von repetitiven nukleinsäuresequenzen durch eine diskontinuierliche verlängerung von startermolekülen - Google Patents
Bestimmung der länge von repetitiven nukleinsäuresequenzen durch eine diskontinuierliche verlängerung von startermolekülenInfo
- Publication number
- ATE290606T1 ATE290606T1 AT99964062T AT99964062T ATE290606T1 AT E290606 T1 ATE290606 T1 AT E290606T1 AT 99964062 T AT99964062 T AT 99964062T AT 99964062 T AT99964062 T AT 99964062T AT E290606 T1 ATE290606 T1 AT E290606T1
- Authority
- AT
- Austria
- Prior art keywords
- nucleic acid
- determination
- length
- acid sequences
- starter molecules
- Prior art date
Links
- 150000007523 nucleic acids Chemical group 0.000 title abstract 2
- 230000003252 repetitive effect Effects 0.000 title 1
- 239000007858 starting material Substances 0.000 title 1
- 239000003153 chemical reaction reagent Substances 0.000 abstract 3
- 239000002773 nucleotide Substances 0.000 abstract 2
- 125000003729 nucleotide group Chemical group 0.000 abstract 2
- 102000039446 nucleic acids Human genes 0.000 abstract 1
- 108020004707 nucleic acids Proteins 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
- C12Q1/6837—Enzymatic or biochemical coupling of nucleic acids to a solid phase using probe arrays or probe chips
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/6858—Allele-specific amplification
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6869—Methods for sequencing
- C12Q1/6874—Methods for sequencing involving nucleic acid arrays, e.g. sequencing by hybridisation
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Physics & Mathematics (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Analytical Chemistry (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/205,114 US6309829B1 (en) | 1997-05-27 | 1998-12-03 | Length determination of nucleic acid repeat sequences by discontinuous primer extension |
| PCT/US1999/028584 WO2000032824A2 (en) | 1998-12-03 | 1999-12-01 | Length determination of nucleic acid repeat sequences by discontinuous primer extension |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE290606T1 true ATE290606T1 (de) | 2005-03-15 |
Family
ID=22760853
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT99964062T ATE290606T1 (de) | 1998-12-03 | 1999-12-01 | Bestimmung der länge von repetitiven nukleinsäuresequenzen durch eine diskontinuierliche verlängerung von startermolekülen |
Country Status (8)
| Country | Link |
|---|---|
| US (4) | US6309829B1 (de) |
| EP (1) | EP1135528B1 (de) |
| JP (2) | JP2002531106A (de) |
| AT (1) | ATE290606T1 (de) |
| AU (1) | AU758964B2 (de) |
| CA (1) | CA2353793A1 (de) |
| DE (1) | DE69924140T2 (de) |
| WO (1) | WO2000032824A2 (de) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6309829B1 (en) * | 1997-05-27 | 2001-10-30 | Pe Corporation (Ny) | Length determination of nucleic acid repeat sequences by discontinuous primer extension |
| US9708358B2 (en) | 2000-10-06 | 2017-07-18 | The Trustees Of Columbia University In The City Of New York | Massive parallel method for decoding DNA and RNA |
| EP3034627B1 (de) | 2000-10-06 | 2019-01-30 | The Trustees of Columbia University in the City of New York | Massives paralleles verfahren zum entschlüsseln von dna und rna |
| US20040185477A1 (en) * | 2003-01-10 | 2004-09-23 | Sention Inc. | Methods of detecting differences in genomic sequence representation |
| GB0324456D0 (en) * | 2003-10-20 | 2003-11-19 | Isis Innovation | Parallel DNA sequencing methods |
| WO2006034387A1 (en) | 2004-09-21 | 2006-03-30 | Applera Corporation | TWO-COLOR REAL-TIME/END-POINT QUANTITATION OF MICRORNAS (miRNAs) |
| WO2006076650A2 (en) * | 2005-01-12 | 2006-07-20 | Applera Corporation | Compositions, methods, and kits for selective amplification of nucleic acids |
| WO2007053702A2 (en) | 2005-10-31 | 2007-05-10 | The Trustees Of Columbia University In The City Of New York | Synthesis of four color 3'-o-allyl modified photocleavable fluorescent nucleotides and related methods |
| US8796432B2 (en) * | 2005-10-31 | 2014-08-05 | The Trustees Of Columbia University In The City Of New York | Chemically cleavable 3'-o-allyl-DNTP-allyl-fluorophore fluorescent nucleotide analogues and related methods |
| US20080038727A1 (en) * | 2006-03-10 | 2008-02-14 | Applera Corporation | MicroRNA and Messenger RNA Detection on Arrays |
| EP2049688B1 (de) | 2006-08-01 | 2018-01-24 | Applied Biosystems, LLC | Nachweis von analyten und nukleinsäuren |
| GB2457402B (en) | 2006-12-01 | 2011-10-19 | Univ Columbia | Four-color DNA sequencing by synthesis using cleavable fluorescent nucleotide reversible terminators |
| EP2207900B1 (de) | 2007-10-19 | 2015-04-29 | The Trustees of Columbia University in the City of New York | Konstruktion und synthese spaltbarer fluoreszenznukleotide als reversible terminatoren für die dna-sequenzierung mittels synthese |
| EP2209911B1 (de) | 2007-10-19 | 2013-10-16 | The Trustees of Columbia University in the City of New York | Dna-sequenzierung mit reversiblen nicht-fluoreszenz-nukleotid-terminatoren und mit einer spaltbaren markierung modifizierten nukleotidterminatoren und eine deoxyinosineverbindung mit einer reversiblen terminatorgruppe |
| US20100330569A1 (en) * | 2009-04-23 | 2010-12-30 | Intelligent Bio-Systems, Inc. | Hydroxymethyl Linkers For Labeling Nucleotides |
| US8592158B2 (en) * | 2009-07-10 | 2013-11-26 | Perkinelmer Health Sciences, Inc. | Detecting multinucleotide repeats |
| US20140170653A1 (en) | 2011-04-15 | 2014-06-19 | Life Technologies Corporation | Chemical ligation |
| US9977861B2 (en) * | 2012-07-18 | 2018-05-22 | Illumina Cambridge Limited | Methods and systems for determining haplotypes and phasing of haplotypes |
| WO2014144883A1 (en) | 2013-03-15 | 2014-09-18 | The Trustees Of Columbia University In The City Of New York | Raman cluster tagged molecules for biological imaging |
| US10557134B2 (en) | 2015-02-24 | 2020-02-11 | Trustees Of Boston University | Protection of barcodes during DNA amplification using molecular hairpins |
| EP3181699A1 (de) | 2015-12-17 | 2017-06-21 | Oniris | Mikro-rnas als prädiktive biomarker von typ-1-diabetes |
| GB201803019D0 (en) * | 2018-02-26 | 2018-04-11 | Univ Newcastle | Methods for detecting target polynucleotides |
Family Cites Families (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5367066A (en) | 1984-10-16 | 1994-11-22 | Chiron Corporation | Oligonucleotides with selectably cleavable and/or abasic sites |
| US5512439A (en) | 1988-11-21 | 1996-04-30 | Dynal As | Oligonucleotide-linked magnetic particles and uses thereof |
| US5075217A (en) | 1989-04-21 | 1991-12-24 | Marshfield Clinic | Length polymorphisms in (dC-dA)n ·(dG-dT)n sequences |
| US5547839A (en) * | 1989-06-07 | 1996-08-20 | Affymax Technologies N.V. | Sequencing of surface immobilized polymers utilizing microflourescence detection |
| US5302509A (en) | 1989-08-14 | 1994-04-12 | Beckman Instruments, Inc. | Method for sequencing polynucleotides |
| US5189056A (en) | 1989-12-19 | 1993-02-23 | University Of North Carolina At Chapel Hill | Protection of moist stratified squamous epithelia against damage from noxious luminal agents |
| IL97222A (en) | 1990-02-16 | 1995-08-31 | Orion Yhtymae Oy | Method and reagent for determining specific nucleotide variations |
| JPH0697522A (ja) * | 1990-11-30 | 1994-04-08 | Internatl Business Mach Corp <Ibm> | 超伝導材料の薄膜の製造方法 |
| US6004744A (en) | 1991-03-05 | 1999-12-21 | Molecular Tool, Inc. | Method for determining nucleotide identity through extension of immobilized primer |
| US5518900A (en) | 1993-01-15 | 1996-05-21 | Molecular Tool, Inc. | Method for generating single-stranded DNA molecules |
| DE4141178A1 (de) | 1991-12-13 | 1993-06-17 | Europ Lab Molekularbiolog | Verfahren zur sequenzierung von nukleinsaeuren |
| EP1382386A3 (de) | 1992-02-19 | 2004-12-01 | The Public Health Research Institute Of The City Of New York, Inc. | Neue Ordnungen für Oligonukleotide und ihr Nutzen zum Sortieren, Isolieren, Sequenzierung und Manipulieren von Nukleinsäuren |
| WO1993019205A1 (en) | 1992-03-19 | 1993-09-30 | The Regents Of The University Of California | Multiple tag labeling method for dna sequencing |
| US5981176A (en) | 1992-06-17 | 1999-11-09 | City Of Hope | Method of detecting and discriminating between nucleic acid sequences |
| US5650277A (en) | 1992-07-02 | 1997-07-22 | Diagenetics Ltd. | Method of determining the presence and quantifying the number of di- and trinucleotide repeats |
| US5374527A (en) | 1993-01-21 | 1994-12-20 | Applied Biosystems, Inc. | High resolution DNA sequencing method using low viscosity medium |
| AU3933393A (en) | 1993-03-17 | 1994-10-11 | City Of Hope | Nucleic acid sequences having single stranded ends |
| US5767259A (en) | 1994-12-27 | 1998-06-16 | Naxcor | Oligonucleotides containing base-free linking groups with photoactivatable side chains |
| US5695933A (en) | 1993-05-28 | 1997-12-09 | Massachusetts Institute Of Technology | Direct detection of expanded nucleotide repeats in the human genome |
| US5610287A (en) | 1993-12-06 | 1997-03-11 | Molecular Tool, Inc. | Method for immobilizing nucleic acid molecules |
| FR2718753B1 (fr) | 1994-04-15 | 1996-07-19 | Pasteur Institut | Procédé de comptage de mono-, di- et trinucléotides répétés dans un génome eucaryote et trousse permettant la mise en Óoeuvre de ce procédé. |
| US5580728A (en) | 1994-06-17 | 1996-12-03 | Perlin; Mark W. | Method and system for genotyping |
| GB9507238D0 (en) * | 1995-04-07 | 1995-05-31 | Isis Innovation | Detecting dna sequence variations |
| US5753439A (en) * | 1995-05-19 | 1998-05-19 | Trustees Of Boston University | Nucleic acid detection methods |
| AU5797696A (en) | 1995-05-19 | 1996-11-29 | Ely Michael Rabani | Parallel multiplex polynucleotide sequencing |
| EP0832287B1 (de) | 1995-06-07 | 2007-10-10 | Solexa, Inc | Oligonukleotid-tags zur sortierung und identifizierung |
| AU735440B2 (en) | 1996-02-09 | 2001-07-05 | Cornell Research Foundation Inc. | Detection of nucleic acid sequence differences using the ligase detection reaction with addressable arrays |
| DE19714288A1 (de) * | 1997-04-07 | 1998-10-08 | Hilti Ag | Bohr- und/oder Meisselgerät |
| US5945284A (en) | 1997-05-27 | 1999-08-31 | The Perkin-Elmer Corporation | Length determination of nucleic acid repeat sequences by discontinuous primer extension |
| US6309829B1 (en) * | 1997-05-27 | 2001-10-30 | Pe Corporation (Ny) | Length determination of nucleic acid repeat sequences by discontinuous primer extension |
-
1998
- 1998-12-03 US US09/205,114 patent/US6309829B1/en not_active Expired - Lifetime
-
1999
- 1999-12-01 AT AT99964062T patent/ATE290606T1/de not_active IP Right Cessation
- 1999-12-01 EP EP99964062A patent/EP1135528B1/de not_active Expired - Lifetime
- 1999-12-01 CA CA002353793A patent/CA2353793A1/en not_active Abandoned
- 1999-12-01 DE DE69924140T patent/DE69924140T2/de not_active Expired - Lifetime
- 1999-12-01 JP JP2000585455A patent/JP2002531106A/ja active Pending
- 1999-12-01 AU AU20375/00A patent/AU758964B2/en not_active Ceased
- 1999-12-01 WO PCT/US1999/028584 patent/WO2000032824A2/en not_active Ceased
-
2001
- 2001-10-22 US US10/038,520 patent/US6773887B2/en not_active Expired - Lifetime
-
2004
- 2004-07-14 US US10/892,403 patent/US7294464B2/en not_active Expired - Fee Related
-
2007
- 2007-03-30 US US11/731,192 patent/US7414115B2/en not_active Expired - Fee Related
-
2010
- 2010-04-13 JP JP2010092670A patent/JP2010213709A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| AU2037500A (en) | 2000-06-19 |
| EP1135528A2 (de) | 2001-09-26 |
| WO2000032824A3 (en) | 2001-05-10 |
| US7414115B2 (en) | 2008-08-19 |
| DE69924140T2 (de) | 2006-01-19 |
| US7294464B2 (en) | 2007-11-13 |
| US20050112619A1 (en) | 2005-05-26 |
| US6773887B2 (en) | 2004-08-10 |
| WO2000032824A2 (en) | 2000-06-08 |
| JP2010213709A (ja) | 2010-09-30 |
| CA2353793A1 (en) | 2000-06-08 |
| JP2002531106A (ja) | 2002-09-24 |
| US20070178519A1 (en) | 2007-08-02 |
| US6309829B1 (en) | 2001-10-30 |
| DE69924140D1 (de) | 2005-04-14 |
| EP1135528B1 (de) | 2005-03-09 |
| AU758964B2 (en) | 2003-04-03 |
| US20040126756A1 (en) | 2004-07-01 |
| WO2000032824A9 (en) | 2001-07-19 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |