ATE290835T1 - Zusammengesetzte gerüstmatrix mit stiftanker zur reparatur und wiederherstellung von gewebe - Google Patents

Zusammengesetzte gerüstmatrix mit stiftanker zur reparatur und wiederherstellung von gewebe

Info

Publication number
ATE290835T1
ATE290835T1 AT02254534T AT02254534T ATE290835T1 AT E290835 T1 ATE290835 T1 AT E290835T1 AT 02254534 T AT02254534 T AT 02254534T AT 02254534 T AT02254534 T AT 02254534T AT E290835 T1 ATE290835 T1 AT E290835T1
Authority
AT
Austria
Prior art keywords
scaffold
porous
restoration
tissue repair
infused
Prior art date
Application number
AT02254534T
Other languages
English (en)
Inventor
Kelly R Brown
Mark C Zimmerman
Yufu Li
Original Assignee
Ethicon Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ethicon Inc filed Critical Ethicon Inc
Application granted granted Critical
Publication of ATE290835T1 publication Critical patent/ATE290835T1/de

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Classifications

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    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/56—Porous materials, e.g. foams or sponges
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    • A61L27/40—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
    • A61L27/42—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having an inorganic matrix
    • A61L27/425—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having an inorganic matrix of phosphorus containing material, e.g. apatite
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    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
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    • A61F2310/00389—The prosthesis being coated or covered with a particular material
    • A61F2310/0097—Coating or prosthesis-covering structure made of pharmaceutical products, e.g. antibiotics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Inorganic Chemistry (AREA)
  • Composite Materials (AREA)
  • Materials Engineering (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Rheumatology (AREA)
  • Dispersion Chemistry (AREA)
  • Materials For Medical Uses (AREA)
  • Prostheses (AREA)
  • Reinforcement Elements For Buildings (AREA)
AT02254534T 2001-06-28 2002-06-27 Zusammengesetzte gerüstmatrix mit stiftanker zur reparatur und wiederherstellung von gewebe ATE290835T1 (de)

Applications Claiming Priority (1)

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US09/893,813 US6626950B2 (en) 2001-06-28 2001-06-28 Composite scaffold with post anchor for the repair and regeneration of tissue

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ATE290835T1 true ATE290835T1 (de) 2005-04-15

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US (1) US6626950B2 (de)
EP (1) EP1277450B1 (de)
JP (1) JP4278927B2 (de)
AT (1) ATE290835T1 (de)
AU (1) AU784508B2 (de)
CA (1) CA2391697A1 (de)
DE (1) DE60203219T2 (de)

Families Citing this family (304)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE220564T1 (de) 1997-08-14 2002-08-15 Sulzer Innotec Ag Zusammensetzung und vorrichtung zur reparatur von knorpelgewebe in vivo bestehend aus nanokapseln mit osteoinduktiven und/oder chondroinduktiven faktoren
US20020095157A1 (en) 1999-07-23 2002-07-18 Bowman Steven M. Graft fixation device combination
US6179840B1 (en) 1999-07-23 2001-01-30 Ethicon, Inc. Graft fixation device and method
CA2393776C (en) 1999-12-15 2009-02-10 Sulzer Orthopedics Ltd. Preparation for repairing cartilage defects or cartilage/bone defects in human or animal joints
US8177841B2 (en) 2000-05-01 2012-05-15 Arthrosurface Inc. System and method for joint resurface repair
US7896885B2 (en) 2002-12-03 2011-03-01 Arthrosurface Inc. Retrograde delivery of resurfacing devices
US6520964B2 (en) 2000-05-01 2003-02-18 Std Manufacturing, Inc. System and method for joint resurface repair
US6610067B2 (en) 2000-05-01 2003-08-26 Arthrosurface, Incorporated System and method for joint resurface repair
US7896883B2 (en) 2000-05-01 2011-03-01 Arthrosurface, Inc. Bone resurfacing system and method
US7678151B2 (en) 2000-05-01 2010-03-16 Ek Steven W System and method for joint resurface repair
US7163541B2 (en) 2002-12-03 2007-01-16 Arthrosurface Incorporated Tibial resurfacing system
CA2365376C (en) 2000-12-21 2006-03-28 Ethicon, Inc. Use of reinforced foam implants with enhanced integrity for soft tissue repair and regeneration
US7597715B2 (en) 2005-04-21 2009-10-06 Biomet Manufacturing Corp. Method and apparatus for use of porous implants
US8123814B2 (en) 2001-02-23 2012-02-28 Biomet Manufacturing Corp. Method and appartus for acetabular reconstruction
US20020120340A1 (en) * 2001-02-23 2002-08-29 Metzger Robert G. Knee joint prosthesis
US7497874B1 (en) 2001-02-23 2009-03-03 Biomet Manufacturing Corp. Knee joint prosthesis
US20030003127A1 (en) * 2001-06-27 2003-01-02 Ethicon, Inc. Porous ceramic/porous polymer layered scaffolds for the repair and regeneration of tissue
JP4691322B2 (ja) * 2001-09-24 2011-06-01 ワルソー・オーソペディック，インコーポレイテッド 多孔質セラミック複合体骨移植片
US7371258B2 (en) * 2001-10-26 2008-05-13 St. Jude Medical, Inc. Valved prosthesis with porous substrate
EP1455689B1 (de) * 2001-10-30 2007-02-21 Eyeborn (Proprietary) Limited Orbitalimplantat
US6712850B2 (en) * 2001-11-30 2004-03-30 Ethicon, Inc. Porous tissue scaffolds for the repair and regeneration of dermal tissue
US8187326B2 (en) * 2002-05-22 2012-05-29 Advanced Technologies And Regenerative Medicine, Llc. Attachment of absorbable tissue scaffolds to fixation devices
US6989034B2 (en) * 2002-05-31 2006-01-24 Ethicon, Inc. Attachment of absorbable tissue scaffolds to fixation devices
US20100185294A1 (en) * 2002-06-04 2010-07-22 Arthrosurface Incorporated Nanorough Alloy Substrate
US7622562B2 (en) 2002-06-26 2009-11-24 Zimmer Orthobiologics, Inc. Rapid isolation of osteoinductive protein mixtures from mammalian bone tissue
US20040002770A1 (en) * 2002-06-28 2004-01-01 King Richard S. Polymer-bioceramic composite for orthopaedic applications and method of manufacture thereof
JP4353510B2 (ja) * 2002-09-09 2009-10-28 株式会社カネカ 組織再生用支持体及びその製造方法
US7824701B2 (en) 2002-10-18 2010-11-02 Ethicon, Inc. Biocompatible scaffold for ligament or tendon repair
US20040078090A1 (en) 2002-10-18 2004-04-22 Francois Binette Biocompatible scaffolds with tissue fragments
US7901408B2 (en) 2002-12-03 2011-03-08 Arthrosurface, Inc. System and method for retrograde procedure
US6994730B2 (en) 2003-01-31 2006-02-07 Howmedica Osteonics Corp. Meniscal and tibial implants
US8388624B2 (en) 2003-02-24 2013-03-05 Arthrosurface Incorporated Trochlear resurfacing system and method
US8197837B2 (en) 2003-03-07 2012-06-12 Depuy Mitek, Inc. Method of preparation of bioabsorbable porous reinforced tissue implants and implants thereof
US6993406B1 (en) 2003-04-24 2006-01-31 Sandia Corporation Method for making a bio-compatible scaffold
US7067123B2 (en) 2003-04-29 2006-06-27 Musculoskeletal Transplant Foundation Glue for cartilage repair
GB0311221D0 (en) * 2003-05-15 2003-06-18 Orthogem Ltd Biomaterial
US7901457B2 (en) 2003-05-16 2011-03-08 Musculoskeletal Transplant Foundation Cartilage allograft plug
ES2306826T3 (es) * 2003-06-24 2008-11-16 Dr. H. C. Robert Mathys Foundation Dispositivo ortopedico para la reparacion de cartilagos.
US8226715B2 (en) 2003-06-30 2012-07-24 Depuy Mitek, Inc. Scaffold for connective tissue repair
US10583220B2 (en) 2003-08-11 2020-03-10 DePuy Synthes Products, Inc. Method and apparatus for resurfacing an articular surface
EP1845890A4 (de) 2003-11-20 2010-06-09 Arthrosurface Inc System und verfahren für rückläufigen vorgang
US7951163B2 (en) 2003-11-20 2011-05-31 Arthrosurface, Inc. Retrograde excision system and apparatus
US7316822B2 (en) 2003-11-26 2008-01-08 Ethicon, Inc. Conformable tissue repair implant capable of injection delivery
EP1537839A1 (de) * 2003-12-02 2005-06-08 Dr. h. c. Robert Mathys Foundation Prothesenvorrchtung zur Knorpelreparatur
US7901461B2 (en) * 2003-12-05 2011-03-08 Ethicon, Inc. Viable tissue repair implants and methods of use
US7666230B2 (en) * 2003-12-08 2010-02-23 Depuy Products, Inc. Implant device for cartilage regeneration in load bearing articulation regions
ES2404682T3 (es) 2003-12-11 2013-05-28 Isto Technologies Inc. Sistema de cartílago particulado
US11395865B2 (en) 2004-02-09 2022-07-26 DePuy Synthes Products, Inc. Scaffolds with viable tissue
US7592431B2 (en) * 2004-02-26 2009-09-22 Immunovative Therapies, Ltd. Biodegradable T-cell Activation device
DK2573166T3 (da) 2004-02-26 2016-07-04 Immunovative Therapies Ltd Fremgangsmåder til fremstilling af T-celler til celleterapi
CA2557231C (en) 2004-03-05 2013-12-31 The Trustees Of Columbia University In The City Of New York Multi-phased, biodegradable and osteointegrative composite scaffold for biological fixation of musculoskeletal soft tissue to bone
CA2557436A1 (en) * 2004-03-05 2005-09-29 The Trustees Of Columbia University In The City Of New York Polymer-ceramic-hydrogel composite scaffold for osteochondral repair
US8221780B2 (en) 2004-04-20 2012-07-17 Depuy Mitek, Inc. Nonwoven tissue scaffold
US8137686B2 (en) 2004-04-20 2012-03-20 Depuy Mitek, Inc. Nonwoven tissue scaffold
US7803182B2 (en) * 2004-05-28 2010-09-28 Cordis Corporation Biodegradable vascular device with buffering agent
US7785615B2 (en) * 2004-05-28 2010-08-31 Cordis Corporation Biodegradable medical implant with encapsulated buffering agent
WO2006004885A2 (en) 2004-06-28 2006-01-12 Arthrosurface, Inc. System for articular surface replacement
US7384430B2 (en) 2004-06-30 2008-06-10 Depuy Products, Inc. Low crystalline polymeric material for orthopaedic implants and an associated method
CA2570521C (en) * 2004-07-12 2013-06-25 Isto Technologies, Inc. Tissue matrix system
US8512730B2 (en) * 2004-07-12 2013-08-20 Isto Technologies, Inc. Methods of tissue repair and compositions therefor
DE102004044102B4 (de) * 2004-09-07 2014-07-31 Technische Universität Dresden Implantat zur Behandlung von osteochondralen Defekten, sowie Verfahren zu dessen Herstellung
US20080140184A1 (en) * 2004-09-30 2008-06-12 Pellegrino-Gensey J Lee Scaffold device
US7837740B2 (en) 2007-01-24 2010-11-23 Musculoskeletal Transplant Foundation Two piece cancellous construct for cartilage repair
US20090319045A1 (en) 2004-10-12 2009-12-24 Truncale Katherine G Cancellous constructs, cartilage particles and combinations of cancellous constructs and cartilage particles
US8796015B2 (en) * 2004-11-09 2014-08-05 Proxy Biomedical Limited Tissue scaffold
US7828853B2 (en) 2004-11-22 2010-11-09 Arthrosurface, Inc. Articular surface implant and delivery system
US20060157882A1 (en) * 2004-12-10 2006-07-20 Simona Percec Filled ultramicrocellular structures
US8017395B2 (en) 2004-12-17 2011-09-13 Lifescan, Inc. Seeding cells on porous supports
US20060140915A1 (en) * 2004-12-28 2006-06-29 Schatz Richard A Veterinary protocol for cellular regeneration
US7896921B2 (en) 2004-12-30 2011-03-01 Depuy Products, Inc. Orthopaedic bearing and method for making the same
US7879275B2 (en) 2004-12-30 2011-02-01 Depuy Products, Inc. Orthopaedic bearing and method for making the same
US7883653B2 (en) 2004-12-30 2011-02-08 Depuy Products, Inc. Method of making an implantable orthopaedic bearing
ITMI20050343A1 (it) * 2005-03-04 2006-09-05 Fin Ceramica Faenza S R L Sostituto cartilagineo e osteocindrale comprendente una struttura multistrato e relativo impiego
US8292967B2 (en) 2005-04-21 2012-10-23 Biomet Manufacturing Corp. Method and apparatus for use of porous implants
US8021432B2 (en) * 2005-12-05 2011-09-20 Biomet Manufacturing Corp. Apparatus for use of porous implants
US8066778B2 (en) 2005-04-21 2011-11-29 Biomet Manufacturing Corp. Porous metal cup with cobalt bearing surface
US8266780B2 (en) 2005-04-21 2012-09-18 Biomet Manufacturing Corp. Method and apparatus for use of porous implants
US7531190B2 (en) * 2005-05-25 2009-05-12 Biomet Manufacturing Corp. Porous ceramic structure containing biologics
AU2006202209B2 (en) 2005-05-27 2011-04-14 Lifescan, Inc. Amniotic fluid derived cells
CN101484575B (zh) * 2005-06-08 2013-10-02 森托科尔公司 用于眼变性的细胞疗法
US7815926B2 (en) 2005-07-11 2010-10-19 Musculoskeletal Transplant Foundation Implant for articular cartilage repair
AU2006282754A1 (en) * 2005-08-26 2007-03-01 Zimmer, Inc. Implants and methods for repair, replacement and treatment of joint disease
US20070055373A1 (en) * 2005-09-08 2007-03-08 Zimmer Spine, Inc. Facet replacement/spacing and flexible spinal stabilization
US8921109B2 (en) 2005-09-19 2014-12-30 Histogenics Corporation Cell-support matrix having narrowly defined uniformly vertically and non-randomly organized porosity and pore density and a method for preparation thereof
US20070087033A1 (en) * 2005-10-14 2007-04-19 Sigg Daniel C Self-fixating scaffolds
US20070100460A1 (en) * 2005-10-27 2007-05-03 Rhodes James M Orthopaedic implant systems with anti-abrasion studs
US8216319B2 (en) * 2005-10-27 2012-07-10 Depuy Products, Inc. Method of repairing a knee joint
US20070122448A1 (en) * 2005-11-28 2007-05-31 Alireza Rezania Compositions and methods to create a vascularized environment for cellular transplantation
ES2528272T3 (es) 2005-12-07 2015-02-06 Isto Technologies Inc. Métodos de reparación de cartílago
CN100446817C (zh) * 2006-02-24 2008-12-31 东华大学 一种用微波加热法制备聚己内酯组织工程载体材料的方法
CN100446818C (zh) * 2006-02-24 2008-12-31 东华大学 一种以聚己内酯为原料的组织工程载体材料及其制备方法
US7941875B1 (en) * 2006-02-27 2011-05-17 Brown Medical Industries Trabecular matrix like protectors and method
EP2021462B1 (de) 2006-04-28 2019-01-09 Lifescan, Inc. Differenzierung menschlicher embryonischer stammzellen
US8741643B2 (en) 2006-04-28 2014-06-03 Lifescan, Inc. Differentiation of pluripotent stem cells to definitive endoderm lineage
KR100737167B1 (ko) 2006-06-16 2007-07-10 한국과학기술연구원 조직공학용 다공성 뼈-연골 복합 지지체의 제조 방법
EP1878450A1 (de) * 2006-07-10 2008-01-16 Ecole Polytechnique Federale De Lausanne (Epfl) Polymerkomposit mit einem Porengradient
CN101505689B (zh) 2006-08-22 2012-08-29 三菱电机株式会社 激光加工装置、植入材料以及植入材料制造装置
EP2076218B1 (de) 2006-10-09 2016-03-09 Active Implants Corporation Meniskusprothesenvorrichtung
US8192491B2 (en) * 2006-10-09 2012-06-05 Active Implants Corporation Meniscus prosthetic device
US9943410B2 (en) 2011-02-28 2018-04-17 DePuy Synthes Products, Inc. Modular tissue scaffolds
US20110282392A1 (en) * 2006-10-30 2011-11-17 Tissue Regeneration Systems, Inc. Degradable cage for bone fusion
ATE539102T1 (de) * 2006-10-31 2012-01-15 Surmodics Pharmaceuticals Inc Kugelförmige polymer-partikel
CN100421736C (zh) * 2006-11-01 2008-10-01 华中科技大学 一种基于仿生结构的叠层梯度复合支架材料及其制备方法
NL1032851C2 (nl) * 2006-11-10 2008-05-14 Fondel Finance B V Kit en werkwijze voor het fixeren van een prothese of deel daarvan en/of het vullen van benige defecten.
US20100047309A1 (en) * 2006-12-06 2010-02-25 Lu Helen H Graft collar and scaffold apparatuses for musculoskeletal tissue engineering and related methods
AU2007332787A1 (en) 2006-12-11 2008-06-19 Arthrosurface Incorporated Retrograde resection apparatus and method
US8696762B2 (en) * 2006-12-11 2014-04-15 Medizinische Hochschule Hannover Implant of cross-linked spider silk threads
US8163549B2 (en) 2006-12-20 2012-04-24 Zimmer Orthobiologics, Inc. Method of obtaining viable small tissue particles and use for tissue repair
US20080154372A1 (en) * 2006-12-21 2008-06-26 Peckham Steven M Osteochondral implant using a growth factor concentration gradient for repair of bone and cartilage tissue
US20100136082A1 (en) * 2006-12-22 2010-06-03 Laboratoire Medidom S.A. In situ system for intra-articular chondral and osseous tissue repair
US8562616B2 (en) 2007-10-10 2013-10-22 Biomet Manufacturing, Llc Knee joint prosthesis system and method for implantation
US8187280B2 (en) 2007-10-10 2012-05-29 Biomet Manufacturing Corp. Knee joint prosthesis system and method for implantation
US8328873B2 (en) 2007-01-10 2012-12-11 Biomet Manufacturing Corp. Knee joint prosthesis system and method for implantation
CN101646403B (zh) 2007-01-10 2013-03-20 拜欧米特制造公司 用于移植的膝关节假体系统
US8163028B2 (en) 2007-01-10 2012-04-24 Biomet Manufacturing Corp. Knee joint prosthesis system and method for implantation
WO2008094597A2 (en) * 2007-01-30 2008-08-07 University Of Georgia Research Foundation, Inc. Early mesoderm cells, a stable population of mesendoderm cells that has utility for generation of endoderm and mesoderm lineages and multipotent migratory cells (mmc)
EP1964583A1 (de) * 2007-02-09 2008-09-03 Royal College of Surgeons in Ireland Verfahren zur Herstellung eines Kollagen/Hydroxyapatitverbundgerüsts
US8753391B2 (en) * 2007-02-12 2014-06-17 The Trustees Of Columbia University In The City Of New York Fully synthetic implantable multi-phased scaffold
US7758643B2 (en) * 2007-02-26 2010-07-20 Biomet Sports Medicine, Llc Stable cartilage defect repair plug
US8435551B2 (en) 2007-03-06 2013-05-07 Musculoskeletal Transplant Foundation Cancellous construct with support ring for repair of osteochondral defects
JP2008272453A (ja) * 2007-03-30 2008-11-13 Jms Co Ltd 多孔質体の製造方法およびその用途
US20080255665A1 (en) * 2007-04-11 2008-10-16 Active Implants Corporation Anchored prosthetic meniscus device
AU2008240191B2 (en) 2007-04-12 2013-09-19 Zimmer, Inc. Compositions and methods for tissue repair
ITTO20070373A1 (it) * 2007-05-29 2008-11-30 Torino Politecnico Coppa acetabolare ceramica monoblocco per protesi d'anca.
US8066770B2 (en) * 2007-05-31 2011-11-29 Depuy Products, Inc. Sintered coatings for implantable prostheses
US20100178313A1 (en) * 2007-06-13 2010-07-15 Fmc Corporation Implantable Degradable Biopolymer Fiber Devices
US9080145B2 (en) 2007-07-01 2015-07-14 Lifescan Corporation Single pluripotent stem cell culture
CN104250632B (zh) 2007-07-01 2018-09-11 生命扫描有限公司 单个多能干细胞培养
EP2014256A1 (de) * 2007-07-12 2009-01-14 Straumann Holding AG Verbundmaterial zur Knochenreparatur
US20090018655A1 (en) * 2007-07-13 2009-01-15 John Brunelle Composite Implant for Surgical Repair
US7998380B2 (en) * 2007-07-13 2011-08-16 Wisconsin Alumni Research Foundation Method of fabricating a tissue engineering scaffold
KR101555824B1 (ko) 2007-07-18 2015-09-25 라이프스캔, 인코포레이티드 인간 배아 줄기 세포의 분화
KR101617243B1 (ko) 2007-07-31 2016-05-02 라이프스캔, 인코포레이티드 인간 배아 줄기 세포의 분화
US8632600B2 (en) 2007-09-25 2014-01-21 Depuy (Ireland) Prosthesis with modular extensions
US8128703B2 (en) 2007-09-28 2012-03-06 Depuy Products, Inc. Fixed-bearing knee prosthesis having interchangeable components
US8715359B2 (en) * 2009-10-30 2014-05-06 Depuy (Ireland) Prosthesis for cemented fixation and method for making the prosthesis
US9204967B2 (en) 2007-09-28 2015-12-08 Depuy (Ireland) Fixed-bearing knee prosthesis having interchangeable components
CA3123528C (en) 2007-11-27 2026-01-13 Lifescan, Inc. Differentiation of human embryonic stem cells to pancreatic cells
US9040072B2 (en) * 2007-12-07 2015-05-26 Ethicon, Inc. Use of coupling agents to improve the interface in absorbable polymer composites
WO2009089340A1 (en) * 2008-01-09 2009-07-16 Innovative Health Technologies, Llc Implant pellets and methods for performing bone augmentation and preservation
JP5232484B2 (ja) * 2008-01-31 2013-07-10 日本特殊陶業株式会社 生体インプラント
BR122017025207B1 (pt) 2008-02-21 2021-03-16 Centocor Ortho Biotech Inc superfície que faz parte de um recipiente ou matriz destinada para uso em uma cultura de células ou análises, desprovida de uma camada de células alimentadoras e desprovida de uma camada adsorvente
DE102008010893B3 (de) * 2008-02-23 2009-07-09 Resorba Wundversorgung Gmbh & Co. Kg Implantat zum Einbringen in einen Alveolarraum
US8043375B2 (en) 2008-03-06 2011-10-25 MoiRai Orthopaedic, LLC Cartilage implants
FR2928828B1 (fr) * 2008-03-21 2010-04-02 Tornier Sa Implant de resurfacage du cartilage
US8361147B2 (en) 2008-04-09 2013-01-29 Active Implants Corporation Meniscus prosthetic devices with anti-migration features
US7991599B2 (en) * 2008-04-09 2011-08-02 Active Implants Corporation Meniscus prosthetic device selection and implantation methods
US8016884B2 (en) * 2008-04-09 2011-09-13 Active Implants Corporation Tensioned meniscus prosthetic devices and associated methods
US7611653B1 (en) * 2008-04-09 2009-11-03 Active Implants Corporation Manufacturing and material processing for prosthetic devices
US8623648B2 (en) 2008-04-24 2014-01-07 Janssen Biotech, Inc. Treatment of pluripotent cells
US20100015711A1 (en) 2008-06-30 2010-01-21 Janet Davis Differentiation of Pluripotent Stem Cells
US8012217B2 (en) * 2008-07-03 2011-09-06 Fellowship of Orthopaedic Researchers, LLC Talar implants and methods of use
US8608801B2 (en) * 2008-07-06 2013-12-17 The Trustees Of Columbia University In The City Of New York Osteochondral implants, arthroplasty methods, devices, and systems
US20110305672A1 (en) 2008-07-25 2011-12-15 University Of Georgia Research Foundation, Inc. COMPOSITIONS FOR MESODERM DERIVED ISL1+ MULTIPOTENT CELLS (IMPs), EPICARDIAL PROGENITOR CELLS (EPCs) AND MULTIPOTENT CD56C CELLS (C56Cs) AND METHODS OF PRODUCING AND USING SAME
EP2318520B1 (de) 2008-07-25 2017-10-11 The University Of Georgia Research Foundation, Inc. Zusammensetzungen für multipotente isl1+zellen (imps), epikardiale vorläuferzellen (epcs) und multipotente cxcr4+cd56+-zellen (c56 cs) aus dem mesoderm und anwendungsverfahren
US20100028307A1 (en) * 2008-07-31 2010-02-04 O'neil John J Pluripotent stem cell differentiation
US9358056B2 (en) 2008-08-13 2016-06-07 Smed-Ta/Td, Llc Orthopaedic implant
WO2010019781A1 (en) 2008-08-13 2010-02-18 Smed-Ta/Td, Llc Drug delivery implants
US9616205B2 (en) 2008-08-13 2017-04-11 Smed-Ta/Td, Llc Drug delivery implants
US9700431B2 (en) 2008-08-13 2017-07-11 Smed-Ta/Td, Llc Orthopaedic implant with porous structural member
CA2734183C (en) * 2008-08-13 2016-11-01 Smed-Ta/Td, Llc Orthopaedic implant with spatially varying porosity
CA2734254C (en) 2008-08-13 2018-06-05 Smed-Ta/Td, Llc Orthopaedic screws
US10842645B2 (en) 2008-08-13 2020-11-24 Smed-Ta/Td, Llc Orthopaedic implant with porous structural member
US9387280B2 (en) * 2008-09-05 2016-07-12 Synovis Orthopedic And Woundcare, Inc. Device for soft tissue repair or replacement
CA2742267C (en) 2008-10-31 2019-06-04 Centocor Ortho Biotech Inc. Differentiation of human embryonic stem cells to the pancreatic endocrine lineage
BRPI0919885A2 (pt) * 2008-10-31 2015-08-11 Centocor Ortho Biotech Inc Diferenciação de células-tronco embrionárias humanas para a linhagem endócrina pancreática
US20100124781A1 (en) 2008-11-20 2010-05-20 Shelley Nelson Pluripotent Stem Cell Culture on Micro-Carriers
AU2009316583B2 (en) * 2008-11-20 2016-04-21 Janssen Biotech, Inc. Methods and compositions for cell attachment and cultivation on planar substrates
US20100151114A1 (en) * 2008-12-17 2010-06-17 Zimmer, Inc. In-line treatment of yarn prior to creating a fabric
US8822610B2 (en) 2008-12-22 2014-09-02 ATRP Solutions, Inc. Control over controlled radical polymerization processes
US8815971B2 (en) 2008-12-22 2014-08-26 ATRP Solutions, Inc. Control over controlled radical polymerization processes
AU2010207472B2 (en) 2009-01-23 2015-05-21 Royal College Of Surgeons In Ireland Layered scaffold suitable for osteochondral repair
KR101073050B1 (ko) * 2009-03-17 2011-10-12 주식회사 제네웰 연골 재생을 위한 다공성 연골-골 복합 지지체의 제조 방법
US20100249832A1 (en) * 2009-03-31 2010-09-30 Joshua Stopek Multizone Implants
US20100249854A1 (en) * 2009-03-31 2010-09-30 Thomas Jonathan D Multizone Implants
US9592043B2 (en) * 2009-03-31 2017-03-14 Covidien Lp Multizone implants
US20100256758A1 (en) * 2009-04-02 2010-10-07 Synvasive Technology, Inc. Monolithic orthopedic implant with an articular finished surface
US8556972B2 (en) * 2009-04-02 2013-10-15 Sevika Holding AG Monolithic orthopedic implant with an articular finished surface
WO2010121250A1 (en) 2009-04-17 2010-10-21 Arthrosurface Incorporated Glenoid resurfacing system and method
EP2429429B1 (de) 2009-04-17 2018-07-25 Arthrosurface Incorporated Schultergelenk-oberflächenersatzsystem
US10945743B2 (en) 2009-04-17 2021-03-16 Arthrosurface Incorporated Glenoid repair system and methods of use thereof
US8475531B1 (en) * 2009-04-21 2013-07-02 Scott A. Maxson Anchored multi-phasic osteochondral construct
WO2010123574A1 (en) 2009-04-23 2010-10-28 Atrp Solutions Inc Star macromolecules for personal and home care
US8173750B2 (en) 2009-04-23 2012-05-08 ATRP Solutions, Inc. Star macromolecules for personal and home care
US9783628B2 (en) 2009-04-23 2017-10-10 ATRP Solutions, Inc. Dual-mechanism thickening agents for hydraulic fracturing fluids
JP5711736B2 (ja) 2009-07-10 2015-05-07 バイオ２ テクノロジーズ，インク． 生体組織工学のためのデバイスおよび方法
US20110206828A1 (en) * 2009-07-10 2011-08-25 Bio2 Technologies, Inc. Devices and Methods for Tissue Engineering
US9775721B2 (en) 2009-07-10 2017-10-03 Bio2 Technologies, Inc. Resorbable interbody device
WO2011008733A2 (en) * 2009-07-14 2011-01-20 Doctors Research Group, Inc. Multi-density polymeric interbody spacer and method for fabrication thereof
US20110015743A1 (en) * 2009-07-14 2011-01-20 Doctors Research Group, Inc. Multi-density polymeric interbody spacer
BR112012001480A2 (pt) 2009-07-20 2015-09-01 Janssen Biotech Inc Diferenciação de células-tronco embriônicas humanas
JP5819826B2 (ja) * 2009-07-20 2015-11-24 ヤンセン バイオテツク，インコーポレーテツド ヒト胚性幹細胞の分化
CA2768644A1 (en) * 2009-07-20 2011-01-27 Janssen Biotech, Inc. Differentiation of human embryonic stem cells
ES2566026T3 (es) 2009-08-25 2016-04-08 Fellowship Of Orthopaedic Researchers, Inc. Implantes trocleares
ES2665006T3 (es) * 2009-10-29 2018-04-24 Janssen Biotech, Inc. Células madre pluripotentes
CA2784415C (en) 2009-12-23 2019-06-18 Jean Xu Differentiation of human embryonic stem cells
US9133439B2 (en) * 2009-12-23 2015-09-15 Janssen Biotech, Inc. Differentiation of human embryonic stem cells
US9011547B2 (en) 2010-01-21 2015-04-21 Depuy (Ireland) Knee prosthesis system
US8444699B2 (en) * 2010-02-18 2013-05-21 Biomet Manufacturing Corp. Method and apparatus for augmenting bone defects
US8974519B2 (en) 2010-02-19 2015-03-10 Cardiovascular Systems, Inc. Therapeutic agent delivery system, device and method for localized application of therapeutic substances to a biological conduit
IT1398443B1 (it) * 2010-02-26 2013-02-22 Lima Lto S P A Ora Limacorporate Spa Elemento protesico integrato
WO2011109279A2 (en) * 2010-03-01 2011-09-09 Centocor Ortho Biotech Inc. Methods for purifying cells derived from pluripotent stem cells
CA2792048A1 (en) 2010-03-05 2011-09-09 Arthrosurface Incorporated Tibial resurfacing system and method
US9752125B2 (en) 2010-05-12 2017-09-05 Janssen Biotech, Inc. Differentiation of human embryonic stem cells
EP2389900B1 (de) * 2010-05-24 2013-03-27 Episurf Medical AB Implantat für eine Knorpelreparatur mit einem abstehenden Bolzen
EP2389905B1 (de) 2010-05-24 2012-05-23 Episurf Medical AB Methode zur Gestaltung eines OP-Kits zur Knorpelreparatur in einem Gelenk
EP2389901B8 (de) * 2010-05-24 2013-05-15 Episurf IP Management AB Implantat zur Knorpelreparatur
EP2389904B1 (de) 2010-05-24 2013-07-24 Episurf IP Management AB OP-Kit zur Knorpelreparatur mit einem Implantat und einem Werkzeugsatz
EP2389899B1 (de) 2010-05-24 2015-04-29 Episurf IP Management AB Methode zur Gestaltung eines OP-Kits zur Knorpelreparatur in einem Gelenk
KR20130100122A (ko) 2010-08-12 2013-09-09 얀센 바이오테크 인코포레이티드 췌장 내분비 전구 세포를 이용한 당뇨병의 치료
US8690956B2 (en) 2010-08-23 2014-04-08 Fellowship Of Orthopaedic Researchers, Inc. Talar implants and methods of use
CN108517310B (zh) 2010-08-31 2022-02-15 詹森生物科技公司 人胚胎干细胞的分化
PH12013500349A1 (en) 2010-08-31 2022-03-30 Janssen Biotech Inc Differentiation of pluripotent stem cells
US8435305B2 (en) 2010-08-31 2013-05-07 Zimmer, Inc. Osteochondral graft delivery device and uses thereof
CA2809300A1 (en) 2010-08-31 2012-03-08 Janssen Biotech, Inc. Differentiation of human embryonic stem cells
WO2012048275A2 (en) 2010-10-08 2012-04-12 Caridianbct, Inc. Configurable methods and systems of growing and harvesting cells in a hollow fiber bioreactor system
EP2640430B1 (de) * 2010-11-17 2016-03-09 Zimmer, Inc. Keramische monoblockimplantate mit osseointegrationsbefestigungsflächen
US9587064B2 (en) 2010-12-08 2017-03-07 ATRP Solutions, Inc. Salt-tolerant star macromolecules
EP2652125B1 (de) 2010-12-15 2017-04-26 Kadimastem Ltd. Aus pluripotenten stammzellen abgeleitete insulinproduzierende zellen
US8551525B2 (en) 2010-12-23 2013-10-08 Biostructures, Llc Bone graft materials and methods
US8691126B2 (en) 2011-01-18 2014-04-08 Wisconsin Alumni Research Foundation Method of fabricating an injection molded component
US8771353B2 (en) 2011-03-08 2014-07-08 DePuy Synthes Products, LLC Method and implant for replacing damaged meniscal tissue
US9066716B2 (en) 2011-03-30 2015-06-30 Arthrosurface Incorporated Suture coil and suture sheath for tissue repair
KR101375828B1 (ko) * 2011-03-31 2014-03-17 인제대학교 산학협력단 골-연골 재생용 복합 지지체, 이의 제조 방법 및 이를 유효성분으로 함유하는 골-연골 질환 치료용 조성물
PH12013502252B1 (en) 2011-05-03 2018-09-21 Immunovative Therapies Ltd Induction of il-12 using immunotherapy
PH12013502253A1 (en) 2011-05-03 2019-11-29 Immunovative Therapies Ltd Methods for handling biological drugs containing living cells
CH705356A2 (de) * 2011-08-11 2013-02-15 Regenhu Ag Körper mit einer Grundstruktur aus Knochenersatzmaterial und Verfahren zur Herstellung.
US9351834B2 (en) 2011-09-12 2016-05-31 Biomet Manufacturing, Llc Negative-positive pressurizable implant
US9113879B2 (en) 2011-12-15 2015-08-25 Ethicon Endo-Surgery, Inc. Devices and methods for endoluminal plication
US9113866B2 (en) 2011-12-15 2015-08-25 Ethicon Endo-Surgery, Inc. Devices and methods for endoluminal plication
US20130165982A1 (en) 2011-12-22 2013-06-27 Arthrosurface Incorporated System and Method for Bone Fixation
KR102203056B1 (ko) 2011-12-22 2021-01-14 얀센 바이오테크 인코포레이티드 인간 배아 줄기 세포의 단일 인슐린 호르몬 양성 세포로의 분화
KR20140131999A (ko) 2012-03-07 2014-11-14 얀센 바이오테크 인코포레이티드 만능 줄기 세포의 증폭 및 유지를 위한 한정 배지
US8992547B2 (en) 2012-03-21 2015-03-31 Ethicon Endo-Surgery, Inc. Methods and devices for creating tissue plications
US9498334B2 (en) * 2012-03-27 2016-11-22 DePuy Synthes Products, Inc. Glenoid defect-filling component
ITUD20120059A1 (it) * 2012-04-06 2013-10-07 Limacorporate Spa Elemento protesico per estremita' ossee quali dita o denti e relativo procedimento di realizzazione
KR102667288B1 (ko) 2012-06-08 2024-05-17 얀센 바이오테크 인코포레이티드 인간 배아 줄기 세포의 췌장 내분비 세포로의 분화
US20130345826A1 (en) 2012-06-22 2013-12-26 Collagen Matrix, Inc. Implants for Bone and Cartilage Repair
WO2014008126A1 (en) 2012-07-03 2014-01-09 Arthrosurface Incorporated System and method for joint resurfacing and repair
CN105189643B (zh) 2012-08-30 2019-01-15 派诺聚合物技术公司 用于水力压裂液的双重机制增稠剂
US9125967B2 (en) * 2012-11-13 2015-09-08 University Of Iowa Research Foundation Fluorapatite glass-ceramics
US10245306B2 (en) 2012-11-16 2019-04-02 Isto Technologies Ii, Llc Flexible tissue matrix and methods for joint repair
EP2931326A1 (de) * 2012-12-11 2015-10-21 Dr.h.c. Robert Mathys Stiftung Knochenersatz und verfahren zu dessen herstellung
US20140178343A1 (en) 2012-12-21 2014-06-26 Jian Q. Yao Supports and methods for promoting integration of cartilage tissue explants
RU2768963C2 (ru) 2012-12-31 2022-03-25 Янссен Байотек, Инк. Культивация эмбриональных стволовых клеток человека в воздушно-жидкостной зоне взаимодействия с целью их дифференцировки в панкреатические эндокринные клетки
WO2014105546A1 (en) 2012-12-31 2014-07-03 Janssen Biotech, Inc. Differentiation of human embryonic stem cells into pancreatic endocrine cells using hb9 regulators
WO2014106141A1 (en) 2012-12-31 2014-07-03 Janssen Biotech, Inc. Suspension and clustering of human pluripotent cells for differentiation into pancreatic endocrine cells
US10370644B2 (en) 2012-12-31 2019-08-06 Janssen Biotech, Inc. Method for making human pluripotent suspension cultures and cells derived therefrom
CN103083729B (zh) * 2013-01-28 2014-08-20 西南科技大学 一种三维多孔复合棒材的制备方法
MX374990B (es) 2013-02-04 2025-03-06 Pilot Polymer Tech Inc Métodos para la elaboración de macromoléculas en forma de estrella tolerantes a las sales que comprende una pluralidad de brazos poliméricos.
US9630346B2 (en) 2013-03-05 2017-04-25 Wisconsin Alumni Research Foundation Method of fabricating an injection molded component
US9724203B2 (en) 2013-03-15 2017-08-08 Smed-Ta/Td, Llc Porous tissue ingrowth structure
US9408699B2 (en) 2013-03-15 2016-08-09 Smed-Ta/Td, Llc Removable augment for medical implant
US9681966B2 (en) 2013-03-15 2017-06-20 Smed-Ta/Td, Llc Method of manufacturing a tubular medical implant
US20160296664A1 (en) 2013-04-12 2016-10-13 The Trustees Of Columbia University In The City Of New York Methods for host cell homing and dental pulp regeneration
DK2986236T3 (da) 2013-04-15 2020-01-20 Episurf Ip Man Ab System til udformning af et styreværktøj og/eller kirurgiske kitværktøjer og/eller et implantat, som omfatter en positioneringsmarkering
US20190231538A1 (en) 2013-04-15 2019-08-01 Episurf Ip-Management Ab Method of designing and positioning a medical implant and an implant comprising a positioning mark
US9492200B2 (en) 2013-04-16 2016-11-15 Arthrosurface Incorporated Suture system and method
ITMI20130636A1 (it) * 2013-04-18 2014-10-19 Novagenit S R L Metodo per la preparazione di biomateriali biocompatibili e biodegradabili a base di collagene e granuli di idrossiapatite/¿-tricalcio fosfato per uso in chirurgia ortopedica e biomateriali così ottenuti
US9555564B2 (en) 2013-11-11 2017-01-31 Wisconsin Alumni Research Foundation Method of fabricating a foamed, injection molded component with improved ductility and toughness
CN105793411B (zh) 2013-11-16 2018-04-17 泰尔茂比司特公司 生物反应器中的细胞扩增
US11607319B2 (en) 2014-03-07 2023-03-21 Arthrosurface Incorporated System and method for repairing articular surfaces
US10624748B2 (en) 2014-03-07 2020-04-21 Arthrosurface Incorporated System and method for repairing articular surfaces
US20150250472A1 (en) 2014-03-07 2015-09-10 Arthrosurface Incorporated Delivery System for Articular Surface Implant
JP6783143B2 (ja) 2014-03-25 2020-11-11 テルモ ビーシーティー、インコーポレーテッド 培地の受動的補充
EP3954759A1 (de) 2014-05-16 2022-02-16 Janssen Biotech, Inc. Verwendung kleiner moleküle zur verstärkung der mafa-expression in endokrinen pankreaszellen
CN107075015B (zh) 2014-07-03 2019-08-23 派诺聚合物技术公司 表面活性剂-相容性星形大分子
WO2016044721A1 (en) 2014-09-19 2016-03-24 Regenerative Medical Solutions, Inc. Compositions and methods for differentiating stem cells into cell populations comprising beta-like cells
US20160090569A1 (en) 2014-09-26 2016-03-31 Terumo Bct, Inc. Scheduled Feed
US10179191B2 (en) 2014-10-09 2019-01-15 Isto Technologies Ii, Llc Flexible tissue matrix and methods for joint repair
US10077420B2 (en) 2014-12-02 2018-09-18 Histogenics Corporation Cell and tissue culture container
US11666447B1 (en) * 2015-03-05 2023-06-06 Taq Ortho, LLC Bone implant augment and offset device
US11678917B1 (en) * 2015-03-05 2023-06-20 Taq Ortho, LLC Bone insert augment and offset method
WO2017004592A1 (en) 2015-07-02 2017-01-05 Terumo Bct, Inc. Cell growth with mechanical stimuli
ITUB20152661A1 (it) * 2015-07-30 2017-01-30 Tecres Spa Dispositivo protesico antibiotato
US9925298B2 (en) 2015-10-27 2018-03-27 Council Of Scientific & Industrial Research Porous polymer scaffold useful for tissue engineering in stem cell transplantation
EP4231015B1 (de) 2015-11-30 2024-10-30 Kadimastem Ltd. Verfahren zur differenzierung und reinigung endokriner pankreaszellen
EP3187196A1 (de) * 2015-12-29 2017-07-05 Fundacíon Tecnalia Research & Innovation Artikel aus uhmwpe-polymer, verfahren zu dessen herstellung und daraus hergestelltes implantat und/oder gerüst
GB201600385D0 (en) 2016-01-08 2016-02-24 Ucl Business Plc Osteochondral scaffold
CA3020905A1 (en) 2016-04-14 2017-10-19 Janssen Biotech, Inc. Differentiation of pluripotent stem cells to intestinal midgut endoderm cells
US11965175B2 (en) 2016-05-25 2024-04-23 Terumo Bct, Inc. Cell expansion
US11685883B2 (en) 2016-06-07 2023-06-27 Terumo Bct, Inc. Methods and systems for coating a cell growth surface
US11104874B2 (en) 2016-06-07 2021-08-31 Terumo Bct, Inc. Coating a bioreactor
WO2018136934A1 (en) * 2017-01-23 2018-07-26 Bōnwrx Ltd Method and apparatus for using elastomeric materials in surgical applications
US11629332B2 (en) 2017-03-31 2023-04-18 Terumo Bct, Inc. Cell expansion
US11624046B2 (en) 2017-03-31 2023-04-11 Terumo Bct, Inc. Cell expansion
US12234441B2 (en) 2017-03-31 2025-02-25 Terumo Bct, Inc. Cell expansion
US12097304B2 (en) 2017-05-10 2024-09-24 Board Of Trustees Of The University Of Arkansas Biocompatible structure for tissue regeneration and methods of making and using same
WO2019022780A1 (en) 2017-07-27 2019-01-31 Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College FUNCTIONAL PANCREATIC CELLS FROM FÉLINSPREADING ADIPOSE TISSUE
WO2019028344A1 (en) 2017-08-04 2019-02-07 Arthrosurface Incorporated JOINT SURFACE IMPLANT WITH MULTIPLE COMPONENTS
US10786370B2 (en) * 2017-12-28 2020-09-29 Industrial Technology Research Institute Cartilage repair implant, auxiliary surgical tool kit and cartilage repair system
US20190314163A1 (en) * 2018-04-16 2019-10-17 Brahm Holdings, Llc Spinal implant and related methods
SE543241C2 (en) 2018-04-27 2020-10-27 Episurf Ip Man Ab An implant for cartilage and / or bone repair
GB2609338B (en) 2019-03-12 2023-06-14 Arthrosurface Inc Humeral and glenoid articular surface implant systems and methods
NL1043315B1 (en) * 2019-06-27 2021-02-01 Jointsphere B V Plug-shaped implant for the replacement and regeneration of biological tissue and method for preparing the implant
US11565021B1 (en) * 2019-08-12 2023-01-31 Ortho Development Corporation Composite structure porous implant for replacing bone stock
US12434302B2 (en) 2019-11-25 2025-10-07 Ortho Development Corporation Method for manufacturing porous structures using additive manufacturing
CN112451741B (zh) * 2020-12-30 2022-09-09 杭州电子科技大学 一种控制药物多级释放的生物活性支架及其制造方法
EP4314244B1 (de) 2021-03-23 2025-07-23 Terumo BCT, Inc. Zellerfassung und -erweiterung
US20240182864A1 (en) 2021-03-24 2024-06-06 Salk Institute For Biological Studies Novel chemical combinations and methods of use thereof, towards differentiation of human progenitor cells into functional beta cells
CN118647345A (zh) * 2021-11-26 2024-09-13 宝丽富乐有限责任公司 植入物
US12152699B2 (en) 2022-02-28 2024-11-26 Terumo Bct, Inc. Multiple-tube pinch valve assembly
USD1099116S1 (en) 2022-09-01 2025-10-21 Terumo Bct, Inc. Display screen or portion thereof with a graphical user interface for displaying cell culture process steps and measurements of an associated bioreactor device
WO2025151535A1 (en) * 2024-01-08 2025-07-17 Hyalex Orthopaedics, Inc. Metatarsophalangeal joint implants and methods thereof

Family Cites Families (59)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3929971A (en) 1973-03-30 1975-12-30 Research Corp Porous biomaterials and method of making same
US4057537A (en) 1975-01-28 1977-11-08 Gulf Oil Corporation Copolymers of L-(-)-lactide and epsilon caprolactone
US4045418A (en) 1975-01-28 1977-08-30 Gulf Oil Corporation Copolymers of D,L-lactide and epsilon caprolactone
US4186448A (en) 1976-04-16 1980-02-05 Brekke John H Device and method for treating and healing a newly created bone void
US4208511A (en) 1977-01-19 1980-06-17 Ethicon, Inc. Isomorphic copolyoxalates and sutures thereof
US4141087A (en) 1977-01-19 1979-02-27 Ethicon, Inc. Isomorphic copolyoxalates and sutures thereof
US4105034A (en) 1977-06-10 1978-08-08 Ethicon, Inc. Poly(alkylene oxalate) absorbable coating for sutures
US4205399A (en) 1977-06-13 1980-06-03 Ethicon, Inc. Synthetic absorbable surgical devices of poly(alkylene oxalates)
US4140678A (en) 1977-06-13 1979-02-20 Ethicon, Inc. Synthetic absorbable surgical devices of poly(alkylene oxalates)
US4130639A (en) 1977-09-28 1978-12-19 Ethicon, Inc. Absorbable pharmaceutical compositions based on isomorphic copolyoxalates
US4479271A (en) * 1981-10-26 1984-10-30 Zimmer, Inc. Prosthetic device adapted to promote bone/tissue ingrowth
US5133755A (en) 1986-01-28 1992-07-28 Thm Biomedical, Inc. Method and apparatus for diodegradable, osteogenic, bone graft substitute device
FI80605C (fi) 1986-11-03 1990-07-10 Biocon Oy Benkirurgisk biokompositmaterial.
CA1340581C (en) 1986-11-20 1999-06-08 Joseph P. Vacanti Chimeric neomorphogenesis of organs by controlled cellular implantation using artificial matrices
DE3644588C1 (de) 1986-12-27 1988-03-10 Ethicon Gmbh Implantat und Verfahren zu seiner Herstellung
US4861733A (en) 1987-02-13 1989-08-29 Interpore International Calcium phosphate bone substitute materials
US5306311A (en) 1987-07-20 1994-04-26 Regen Corporation Prosthetic articular cartilage
GB2215209B (en) 1988-03-14 1992-08-26 Osmed Inc Method and apparatus for biodegradable, osteogenic, bone graft substitute device
US5108755A (en) * 1989-04-27 1992-04-28 Sri International Biodegradable composites for internal medical use
US5067964A (en) 1989-12-13 1991-11-26 Stryker Corporation Articular surface repair
GB8928250D0 (en) 1989-12-14 1990-02-21 Erba Carlo Spa Use of supercritical fluids to obtain porous sponges of biodegradable polymers
US5486359A (en) 1990-11-16 1996-01-23 Osiris Therapeutics, Inc. Human mesenchymal stem cells
JP3007903B2 (ja) 1991-03-29 2000-02-14 京セラ株式会社 人工椎間板
US5502159A (en) 1991-04-17 1996-03-26 United States Surgical Corporation Absorbable composition
US5225520A (en) 1991-04-17 1993-07-06 United States Surgical Corporation Absorbable composition
DE69307299T2 (de) 1992-02-14 1997-04-30 Board of Regents, the University of Texas System, Austin, Tex. Mehrphasiges, biologisch abbaubares implantat/träger und verfahren zu seiner herstellung
US5468253A (en) 1993-01-21 1995-11-21 Ethicon, Inc. Elastomeric medical device
US5514378A (en) 1993-02-01 1996-05-07 Massachusetts Institute Of Technology Biocompatible polymer membranes and methods of preparation of three dimensional membrane structures
US5403347A (en) 1993-05-27 1995-04-04 United States Surgical Corporation Absorbable block copolymers and surgical articles fabricated therefrom
US5522895A (en) 1993-07-23 1996-06-04 Rice University Biodegradable bone templates
AU7564494A (en) 1993-08-13 1995-03-14 Smith & Nephew Richards Inc. Microporous polymeric foams and microtextured surfaces
WO1995008354A1 (en) 1993-09-24 1995-03-30 Takiron Co., Ltd. Implantation material
US5431679A (en) 1994-03-10 1995-07-11 United States Surgical Corporation Absorbable block copolymers and surgical articles fabricated therefrom
US5686091A (en) 1994-03-28 1997-11-11 The Johns Hopkins University School Of Medicine Biodegradable foams for cell transplantation
US5632745A (en) 1995-02-07 1997-05-27 R&D Biologicals, Inc. Surgical implantation of cartilage repair unit
US5769899A (en) 1994-08-12 1998-06-23 Matrix Biotechnologies, Inc. Cartilage repair unit
US5749874A (en) 1995-02-07 1998-05-12 Matrix Biotechnologies, Inc. Cartilage repair unit and method of assembling same
US5713374A (en) 1995-02-10 1998-02-03 The Hospital For Joint Diseases Orthopaedic Institute Fixation method for the attachment of wound repair materials to cartilage defects
US5464929A (en) 1995-03-06 1995-11-07 Ethicon, Inc. Absorbable polyoxaesters
US5595751A (en) 1995-03-06 1997-01-21 Ethicon, Inc. Absorbable polyoxaesters containing amines and/or amido groups
US5607687A (en) 1995-03-06 1997-03-04 Ethicon, Inc. Polymer blends containing absorbable polyoxaesters
US5700583A (en) 1995-03-06 1997-12-23 Ethicon, Inc. Hydrogels of absorbable polyoxaesters containing amines or amido groups
US5618552A (en) 1995-03-06 1997-04-08 Ethicon, Inc. Absorbable polyoxaesters
US5597579A (en) 1995-03-06 1997-01-28 Ethicon, Inc. Blends of absorbable polyoxaamides
US5859150A (en) 1995-03-06 1999-01-12 Ethicon, Inc. Prepolymers of absorbable polyoxaesters
US5698213A (en) 1995-03-06 1997-12-16 Ethicon, Inc. Hydrogels of absorbable polyoxaesters
US5648088A (en) 1995-03-06 1997-07-15 Ethicon, Inc. Blends of absorbable polyoxaesters containing amines and/or amide groups
US5716413A (en) 1995-10-11 1998-02-10 Osteobiologics, Inc. Moldable, hand-shapable biodegradable implant material
GB9522478D0 (en) * 1995-11-02 1996-01-03 Howmedica Prosthetic bearing element and implant incorporating such an element
US5723508A (en) 1996-01-25 1998-03-03 Northwestern University Method of fabricating emulsion freeze-dried scaffold bodies and resulting products
US6296667B1 (en) 1997-10-01 2001-10-02 Phillips-Origen Ceramic Technology, Llc Bone substitutes
US6136029A (en) 1997-10-01 2000-10-24 Phillips-Origen Ceramic Technology, Llc Bone substitute materials
NL1010248C1 (nl) 1998-10-05 2000-04-06 Armand Francois Victor Mathijs Werkwijze voor het impregneren van poreuze, steenachtige objecten.
EP1027897B1 (de) 1999-02-10 2005-04-13 IsoTis N.V. Verfahren zur Knorpelgeweberegeneration
US6103255A (en) 1999-04-16 2000-08-15 Rutgers, The State University Porous polymer scaffolds for tissue engineering
US6251143B1 (en) 1999-06-04 2001-06-26 Depuy Orthopaedics, Inc. Cartilage repair unit
DE19933382A1 (de) 1999-07-16 2001-02-01 Eska Implants Gmbh & Co Füllimplantat für Knorpel- und Knochendefekte in einem Gelenk
CA2393776C (en) 1999-12-15 2009-02-10 Sulzer Orthopedics Ltd. Preparation for repairing cartilage defects or cartilage/bone defects in human or animal joints
US20020183858A1 (en) * 2001-06-05 2002-12-05 Contiliano Joseph H. Attachment of absorbable tissue scaffolds to scaffold fixation devices

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