ATE292630T1 - 3-(1-hydroxy-pentylidene)-5-nitro-3h-benzofuran 2-on, ein verfahren zu seiner herstellung und seine verwendung - Google Patents

3-(1-hydroxy-pentylidene)-5-nitro-3h-benzofuran 2-on, ein verfahren zu seiner herstellung und seine verwendung

Info

Publication number: ATE292630T1
Authority: AT; Austria
Prior art keywords: pentylidene; benzofuran; nitro; hydroxy; production
Prior art date: 2000-01-17

Application number

AT01810033T

Other languages

English (en)

Inventor

Alain Schouteeten

Francoise Mordacq

Original Assignee

Clariant France Sa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-01-17

Filing date

2001-01-15

Publication date

2005-04-15

2001-01-15 Application filed by Clariant France Sa filed Critical Clariant France Sa

2005-04-15 Application granted granted Critical

2005-04-15 Publication of ATE292630T1 publication Critical patent/ATE292630T1/de

Links

238000000034 method Methods 0.000 title abstract 3
RJMPDGNCDFVLHH-UHFFFAOYSA-N 3-(1-hydroxypentylidene)-5-nitro-1-benzofuran-2-one Chemical compound C1=C([N+]([O-])=O)C=C2C(=C(O)CCCC)C(=O)OC2=C1 RJMPDGNCDFVLHH-UHFFFAOYSA-N 0.000 title abstract 2
238000004519 manufacturing process Methods 0.000 title abstract 2
150000001875 compounds Chemical class 0.000 abstract 2
238000002360 preparation method Methods 0.000 abstract 2
230000015572 biosynthetic process Effects 0.000 abstract 1
239000000543 intermediate Substances 0.000 abstract 1
238000003786 synthesis reaction Methods 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/82—Benzo [b] furans; Hydrogenated benzo [b] furans with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
- C07D307/83—Oxygen atoms

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Furan Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

AT01810033T 2000-01-17 2001-01-15 3-(1-hydroxy-pentylidene)-5-nitro-3h-benzofuran 2-on, ein verfahren zu seiner herstellung und seine verwendung ATE292630T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
FR0000523A FR2803846B1 (fr)	2000-01-17	2000-01-17	3-(1-hydroxy-pentylidene)-5-nitro-3h-benzofuran-2-one, son procede de preparation et son utilisation

Publications (1)

Publication Number	Publication Date
ATE292630T1 true ATE292630T1 (de)	2005-04-15

Family

ID=8845968

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT01810033T ATE292630T1 (de)	2000-01-17	2001-01-15	3-(1-hydroxy-pentylidene)-5-nitro-3h-benzofuran 2-on, ein verfahren zu seiner herstellung und seine verwendung

Country Status (13)

Country	Link
US (2)	US6515147B2 (de)
EP (1)	EP1116719B1 (de)
JP (1)	JP4408578B2 (de)
KR (1)	KR100788529B1 (de)
CN (1)	CN1204133C (de)
AT (1)	ATE292630T1 (de)
DE (1)	DE60109829T2 (de)
DK (1)	DK1116719T3 (de)
ES (1)	ES2238408T3 (de)
FR (1)	FR2803846B1 (de)
HU (1)	HUP0100146A3 (de)
NO (1)	NO327039B1 (de)
TW (1)	TW564246B (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE10237819A1 (de)	2002-08-19	2004-03-04	Bayer Ag	5-Nitrobenzofurane
FR2864536B1 (fr) *	2003-12-24	2006-03-17	Clariant France Sa	Procede de preparation de n-alkyl-2 (hydroxy-4-benzoyl)-3 benzofurannes et intermediaires pour sa mise en oeuvre
GB0719180D0 (en) *	2007-10-02	2007-11-14	Cambrex Karlskoga Ab	New process
TWI519298B (zh)	2008-04-17	2016-02-01	賽諾菲安萬特公司	決奈達隆（ｄｒｏｎｅｄａｒｏｎｅ）於製備用於預防心血管疾病住院或死亡之藥劑之用途
FR2930149B1 (fr) *	2008-04-17	2011-02-18	Sanofi Aventis	Association de dronedarone avec au moins un diuretique, son application en therapeutique
EP2116239A1 (de) *	2008-04-29	2009-11-11	Sanofi-Aventis	Verfahren zur Verwaltung von Risiken in Zusammenhang mit der Zunahme von Serumkreatinin bei der Dronedaron-Behandlung
EP2246341A1 (de)	2009-01-23	2010-11-03	Lonza Ltd.	Verfahren zur Herstellung von 2-Alkyl-3-aroyl-5-nitro-benzofuranen
CN102276561A (zh) *	2010-06-09	2011-12-14	江苏恒瑞医药股份有限公司	决奈达隆及其盐的制备方法
US8602215B2 (en)	2010-06-30	2013-12-10	Sanofi	Methods for reducing the risk of an adverse dronedarone/beta-blockers interaction in a patient suffering from atrial fibrillation

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3248401A (en) *		1966-04-26		Diethylaminoe hoxybenzoyl benzofurans
US4252817A (en) *	1975-03-12	1981-02-24	Sandoz Ltd.	Substituted-2,3-dihydrobenzofuran-2-ones
FR2642755B1 (de) *	1989-02-07	1993-11-05	Sanofi
FR2665444B1 (fr) *	1990-08-06	1992-11-27	Sanofi Sa	Derives d'amino-benzofuranne, benzothiophene ou indole, leur procede de preparation ainsi que les compositions les contenant.
GB9416219D0 (en) *	1994-08-11	1994-10-05	Karobio Ab	Receptor ligands

2000
- 2000-01-17 FR FR0000523A patent/FR2803846B1/fr not_active Expired - Fee Related
2001
- 2001-01-10 TW TW090100495A patent/TW564246B/zh not_active IP Right Cessation
- 2001-01-15 EP EP01810033A patent/EP1116719B1/de not_active Expired - Lifetime
- 2001-01-15 AT AT01810033T patent/ATE292630T1/de active
- 2001-01-15 ES ES01810033T patent/ES2238408T3/es not_active Expired - Lifetime
- 2001-01-15 HU HU0100146A patent/HUP0100146A3/hu unknown
- 2001-01-15 DE DE60109829T patent/DE60109829T2/de not_active Expired - Lifetime
- 2001-01-15 DK DK01810033T patent/DK1116719T3/da active
- 2001-01-16 JP JP2001007465A patent/JP4408578B2/ja not_active Expired - Fee Related
- 2001-01-16 KR KR1020010002333A patent/KR100788529B1/ko not_active Expired - Fee Related
- 2001-01-16 NO NO20010265A patent/NO327039B1/no not_active IP Right Cessation
- 2001-01-17 CN CNB01101296XA patent/CN1204133C/zh not_active Expired - Fee Related
- 2001-01-17 US US09/761,452 patent/US6515147B2/en not_active Ceased
2005
- 2005-02-03 US US11/050,627 patent/USRE39755E1/en not_active Expired - Lifetime

Also Published As

Publication number	Publication date
NO20010265D0 (no)	2001-01-16
JP2001233870A (ja)	2001-08-28
DK1116719T3 (da)	2005-07-18
USRE39755E1 (en)	2007-07-31
CN1306000A (zh)	2001-08-01
DE60109829T2 (de)	2006-01-19
HUP0100146A2 (hu)	2002-01-28
HU0100146D0 (en)	2001-03-28
NO327039B1 (no)	2009-04-06
US20010012900A1 (en)	2001-08-09
EP1116719B1 (de)	2005-04-06
ES2238408T3 (es)	2005-09-01
KR100788529B1 (ko)	2007-12-24
EP1116719A3 (de)	2001-10-24
FR2803846A1 (fr)	2001-07-20
KR20010076278A (ko)	2001-08-11
FR2803846B1 (fr)	2002-04-05
US6515147B2 (en)	2003-02-04
NO20010265L (no)	2001-07-18
HUP0100146A3 (en)	2003-07-28
EP1116719A2 (de)	2001-07-18
DE60109829D1 (de)	2005-05-12
CN1204133C (zh)	2005-06-01
TW564246B (en)	2003-12-01
JP4408578B2 (ja)	2010-02-03

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2005-11-15

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