ATE293883T1 - Verwendung von antioxidantien zur behandlung cholestatischer lebererkrankungen - Google Patents
Verwendung von antioxidantien zur behandlung cholestatischer lebererkrankungenInfo
- Publication number
- ATE293883T1 ATE293883T1 AT97901425T AT97901425T ATE293883T1 AT E293883 T1 ATE293883 T1 AT E293883T1 AT 97901425 T AT97901425 T AT 97901425T AT 97901425 T AT97901425 T AT 97901425T AT E293883 T1 ATE293883 T1 AT E293883T1
- Authority
- AT
- Austria
- Prior art keywords
- antioxidants
- liver disease
- cholestatic liver
- treat cholestatic
- treat
- Prior art date
Links
- 206010008635 Cholestasis Diseases 0.000 title abstract 2
- 239000003963 antioxidant agent Substances 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- 206010067125 Liver injury Diseases 0.000 abstract 1
- 231100000359 cholestasis Toxicity 0.000 abstract 1
- 230000007870 cholestasis Effects 0.000 abstract 1
- 208000019425 cirrhosis of liver Diseases 0.000 abstract 1
- 230000004761 fibrosis Effects 0.000 abstract 1
- 238000009472 formulation Methods 0.000 abstract 1
- 231100000753 hepatic injury Toxicity 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/04—Sulfur, selenium or tellurium; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Inorganic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines Containing Plant Substances (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US1004996P | 1996-01-16 | 1996-01-16 | |
| PCT/US1997/000403 WO1997025864A1 (en) | 1996-01-16 | 1997-01-15 | Use of antioxidant agents to treat cholestatic liver disease |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE293883T1 true ATE293883T1 (de) | 2005-05-15 |
Family
ID=21743557
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT97901425T ATE293883T1 (de) | 1996-01-16 | 1997-01-15 | Verwendung von antioxidantien zur behandlung cholestatischer lebererkrankungen |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US6069167A (de) |
| EP (1) | EP0893949B1 (de) |
| AT (1) | ATE293883T1 (de) |
| AU (1) | AU724620B2 (de) |
| CA (1) | CA2242991C (de) |
| DE (1) | DE69733132D1 (de) |
| WO (1) | WO1997025864A1 (de) |
Families Citing this family (51)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9722361D0 (en) * | 1997-10-24 | 1997-12-17 | Pharma Nord Uk Ltd | Pharmaceutical formulation for treating liver disorders |
| US6616942B1 (en) * | 1999-03-29 | 2003-09-09 | Soft Gel Technologies, Inc. | Coenzyme Q10 formulation and process methodology for soft gel capsules manufacturing |
| US6623734B2 (en) * | 2000-06-22 | 2003-09-23 | Soft Gel Technologies, Inc. | Super absorption coenzyme Q10 |
| US6855733B2 (en) * | 2001-01-24 | 2005-02-15 | Soft Gel Technologies, Inc. | Formulation and manufacturing process for coenzyme Q10 soft gel capsules |
| US6596762B2 (en) | 2001-05-17 | 2003-07-22 | The Regents Of The University Of Colorado | Antioxidant compositions and use for treatment of hepatic steatosis and steatohepatitis |
| US20080089877A1 (en) * | 2003-08-14 | 2008-04-17 | Udell Ronald G | Super Absorption Coenzyme Q10 |
| WO2005023274A1 (en) * | 2003-09-05 | 2005-03-17 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Treatment and prevention of inflammatory disease and mitochondrial dysfunction with high dose selenium |
| US7169385B2 (en) * | 2003-09-29 | 2007-01-30 | Ronald G. Udell | Solubilized CoQ-10 and carnitine |
| US8105583B2 (en) * | 2003-09-29 | 2012-01-31 | Soft Gel Technologies, Inc. | Solubilized CoQ-10 |
| US8124072B2 (en) | 2003-09-29 | 2012-02-28 | Soft Gel Technologies, Inc. | Solubilized CoQ-10 |
| US20050074444A1 (en) * | 2003-10-01 | 2005-04-07 | Papas Andreas M. | Coenzyme Q10 treatment for cystic fibrosis |
| US20050107465A1 (en) * | 2003-10-01 | 2005-05-19 | Papas Andreas M. | Composition for treating inflammatory bowel disease |
| TW200524579A (en) * | 2003-11-28 | 2005-08-01 | Kaneka Corp | Composition for protecting liver functions |
| US7790190B2 (en) * | 2004-03-20 | 2010-09-07 | Yasoo Health, Inc. | Aqueous emulsions of lipophile solubilized with vitamin E TPGS and linoleic acid |
| US7284385B2 (en) * | 2004-09-16 | 2007-10-23 | Hess Spencer W | Pre-dried air reactivation for diesel fuel heated dessicant reactivator |
| DE102004049339A1 (de) * | 2004-10-08 | 2006-04-13 | Basf Ag | Verfahren zur Reinigung von phosphorhaltigen Chelat-Liganden |
| WO2006092449A2 (en) * | 2005-03-02 | 2006-09-08 | Metanomics Gmbh | Process for the production of fine chemicals |
| US20070167422A1 (en) * | 2006-01-18 | 2007-07-19 | Yu Kwok S | Pharmaceutical compositions comprising 17-allylamino-17-demethoxygeldanamycin |
| EP2063905B1 (de) | 2006-09-18 | 2014-07-30 | Raptor Pharmaceutical Inc | Behandlungen von lebererkrankungen durch verabreichung von konjugaten aus rezeptor-assoziierten proteinen |
| US8343541B2 (en) * | 2007-03-15 | 2013-01-01 | Soft Gel Technologies, Inc. | Ubiquinol and alpha lipoic acid compositions |
| WO2008116171A1 (en) * | 2007-03-21 | 2008-09-25 | Raptor Pharmaceutical Inc. | Cyclic receptor-associated protein (rap) peptides |
| EP2346519B1 (de) | 2008-10-02 | 2015-12-02 | George Zabrecky | Verfahren und formulierungen zur behandlung von chronischer lebererkrankung |
| ES2687027T3 (es) | 2010-11-04 | 2018-10-23 | Albireo Ab | Inhibidores de ibat para el tratamiento de enfermedades hepáticas |
| DK2637646T3 (en) * | 2010-11-08 | 2016-08-29 | Albireo Ab | PHARMACEUTICAL COMBINATION CONTAINING AN IBAT inhibitor and a bile acid binder |
| US20130108573A1 (en) | 2011-10-28 | 2013-05-02 | Lumena Pharmaceuticals, Inc. | Bile Acid Recycling Inhibitors for Treatment of Hypercholemia and Cholestatic Liver Disease |
| AU2012328526B2 (en) | 2011-10-28 | 2017-05-25 | Shire Human Genetic Therapies, Inc. | Bile acid recycling inhibitors for treatment of pediatric cholestatic liver diseases |
| JO3301B1 (ar) | 2013-04-26 | 2018-09-16 | Albireo Ab | تعديلات بلورية على إيلوبيكسيبات |
| CN106659726A (zh) | 2014-06-25 | 2017-05-10 | Ea制药株式会社 | 固体制剂及其着色防止或着色减少方法 |
| EP3012252A1 (de) | 2014-10-24 | 2016-04-27 | Ferring BV | Kristalline Form von elobixibat |
| US20160367620A1 (en) | 2015-06-19 | 2016-12-22 | Harry B. Demopoulos | Glutathione |
| CN108601739B (zh) | 2016-02-09 | 2022-01-04 | 阿尔比里奥公司 | 考来烯胺丸剂及其制备方法 |
| ES2874669T3 (es) | 2016-02-09 | 2021-11-05 | Albireo Ab | Formulación oral de colestiramina y uso de la misma |
| WO2017138878A1 (en) | 2016-02-09 | 2017-08-17 | Albireo Ab | Oral cholestyramine formulation and use thereof |
| CN111032019B (zh) | 2017-08-09 | 2022-07-05 | 阿尔比里奥公司 | 考来烯胺颗粒、口服考来烯胺制剂及其用途 |
| CN112449637B (zh) | 2018-06-05 | 2024-03-19 | 阿尔比里奥公司 | 苯并硫杂(二)氮杂环庚三烯化合物及其作为胆汁酸调节剂的用途 |
| US11801226B2 (en) | 2018-06-20 | 2023-10-31 | Albireo Ab | Pharmaceutical formulation of odevixibat |
| PL3810581T3 (pl) | 2018-06-20 | 2025-04-28 | Albireo Ab | Modyfikacje kryształu odewiksibatu |
| US11549878B2 (en) | 2018-08-09 | 2023-01-10 | Albireo Ab | In vitro method for determining the adsorbing capacity of an insoluble adsorbant |
| US11007142B2 (en) | 2018-08-09 | 2021-05-18 | Albireo Ab | Oral cholestyramine formulation and use thereof |
| US10722457B2 (en) | 2018-08-09 | 2020-07-28 | Albireo Ab | Oral cholestyramine formulation and use thereof |
| TWI835997B (zh) | 2019-02-06 | 2024-03-21 | 瑞典商艾爾比瑞歐公司 | 苯并噻氮呯化合物及其用作膽酸調節劑之用途 |
| CN118852054A (zh) | 2019-02-06 | 2024-10-29 | 阿尔比里奥公司 | 苯并硫杂二氮杂环庚三烯化合物及其用作胆汁酸调节剂的用途 |
| ES2973355T3 (es) | 2019-12-04 | 2024-06-19 | Albireo Ab | Compuestos de benzotia(di)azepina y su uso como moduladores del ácido biliar |
| JP7696898B2 (ja) | 2019-12-04 | 2025-06-23 | アルビレオ・アクチボラグ | ベンゾチア(ジ)アゼピン化合物及び胆汁酸モジュレータとしてのそれらの使用 |
| EP4069247B1 (de) | 2019-12-04 | 2025-03-26 | Albireo AB | Benzothiadiazepinverbindungen und ihre verwendung als gallensäuremodulatoren |
| US11014898B1 (en) | 2020-12-04 | 2021-05-25 | Albireo Ab | Benzothiazepine compounds and their use as bile acid modulators |
| IL293379B2 (en) | 2019-12-04 | 2026-04-01 | Albireo Ab | Benzothia(dia)azepine compounds and their use as bile acid modulators |
| EP4188541B1 (de) | 2020-08-03 | 2024-12-25 | Albireo AB | Benzothia(di)azepin-verbindungen und ihre verwendung als gallensäuremodulatoren |
| CA3196488A1 (en) | 2020-11-12 | 2022-05-19 | Albireo Ab | Odevixibat for treating progressive familial intrahepatic cholestasis (pfic) |
| BR112023010799A2 (pt) | 2020-12-04 | 2023-10-03 | Albireo Ab | Compostos de benzotia(di)azepina e seus usos como moduladores de ácidos biliares |
| TW202313579A (zh) | 2021-06-03 | 2023-04-01 | 瑞典商艾爾比瑞歐公司 | 苯并噻(二)氮呯(benzothia(di)azepine)化合物及其作為膽酸調節劑之用途 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS59502024A (ja) * | 1982-11-16 | 1984-12-06 | イレナ モッチャン マルス | リュウマチ性疾病治療剤 |
| DE69122099T2 (de) * | 1990-05-16 | 1997-04-17 | Margaret Hanausek | Zusammensetzung und verfahren zur prävention und behandlung von hypercholesterinämie und zellproliferationsstorungen |
| US5308627A (en) * | 1990-08-07 | 1994-05-03 | Umbdenstock Jr Anthony J | Nutritional supplement for optimizing cellular health |
| WO1993013660A1 (en) * | 1992-01-06 | 1993-07-22 | Health Maintenance Programs, Inc. | Pharmaceutically active antioxydant containing composition and the method of its use to prevent and treat restenosis following angioplasty |
| CN1080855A (zh) * | 1993-05-22 | 1994-01-19 | 黎均耀 | 维生素矿物质防癌复方 |
| DE4322070A1 (de) * | 1993-07-02 | 1995-01-12 | Ploch Eva Marina | Umweltkapsel |
-
1997
- 1997-01-15 AU AU15329/97A patent/AU724620B2/en not_active Expired
- 1997-01-15 WO PCT/US1997/000403 patent/WO1997025864A1/en not_active Ceased
- 1997-01-15 US US08/784,247 patent/US6069167A/en not_active Expired - Fee Related
- 1997-01-15 DE DE69733132T patent/DE69733132D1/de not_active Expired - Lifetime
- 1997-01-15 CA CA002242991A patent/CA2242991C/en not_active Expired - Lifetime
- 1997-01-15 AT AT97901425T patent/ATE293883T1/de not_active IP Right Cessation
- 1997-01-15 EP EP97901425A patent/EP0893949B1/de not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| AU724620B2 (en) | 2000-09-28 |
| AU1532997A (en) | 1997-08-11 |
| CA2242991A1 (en) | 1997-07-24 |
| DE69733132D1 (de) | 2005-06-02 |
| WO1997025864A1 (en) | 1997-07-24 |
| EP0893949A4 (de) | 2002-01-02 |
| EP0893949B1 (de) | 2005-04-27 |
| CA2242991C (en) | 2007-07-24 |
| US6069167A (en) | 2000-05-30 |
| EP0893949A1 (de) | 1999-02-03 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |