ATE294165T1 - Wirksames verfahren zur herstellung von 1,4- dihydro-2h-3, 1-benzoxazin-2-on - Google Patents

Wirksames verfahren zur herstellung von 1,4- dihydro-2h-3, 1-benzoxazin-2-on

Info

Publication number
ATE294165T1
ATE294165T1 AT98906255T AT98906255T ATE294165T1 AT E294165 T1 ATE294165 T1 AT E294165T1 AT 98906255 T AT98906255 T AT 98906255T AT 98906255 T AT98906255 T AT 98906255T AT E294165 T1 ATE294165 T1 AT E294165T1
Authority
AT
Austria
Prior art keywords
benzoxazin
dihydro
producing
effective method
effective
Prior art date
Application number
AT98906255T
Other languages
English (en)
Inventor
Lisa F Frey
Richard D Tillyer
Edward J J Grabowski
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9706082.6A external-priority patent/GB9706082D0/en
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Application granted granted Critical
Publication of ATE294165T1 publication Critical patent/ATE294165T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/04—1,3-Oxazines; Hydrogenated 1,3-oxazines
    • C07D265/12—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems
    • C07D265/14—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D265/18—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring with hetero atoms directly attached in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C271/06—Esters of carbamic acids
    • C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
    • C07C271/26—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atom of at least one of the carbamate groups bound to a carbon atom of a six-membered aromatic ring
    • C07C271/28—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atom of at least one of the carbamate groups bound to a carbon atom of a six-membered aromatic ring to a carbon atom of a non-condensed six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/02—Systems containing only non-condensed rings with a three-membered ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT98906255T 1997-02-12 1998-02-09 Wirksames verfahren zur herstellung von 1,4- dihydro-2h-3, 1-benzoxazin-2-on ATE294165T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US3705997P 1997-02-12 1997-02-12
GBGB9706082.6A GB9706082D0 (en) 1997-03-24 1997-03-24 Efficient synthesis of A 1,4-dihydro-2H-3,1-benzoxazin-2-one
PCT/US1998/002495 WO1998034928A1 (en) 1997-02-12 1998-02-09 Efficient synthesis of a 1,4-dihydro-2h-3,1-benzoxazin-2-one

Publications (1)

Publication Number Publication Date
ATE294165T1 true ATE294165T1 (de) 2005-05-15

Family

ID=26311250

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98906255T ATE294165T1 (de) 1997-02-12 1998-02-09 Wirksames verfahren zur herstellung von 1,4- dihydro-2h-3, 1-benzoxazin-2-on

Country Status (13)

Country Link
EP (1) EP0968197B1 (de)
CN (1) CN1073992C (de)
AR (1) AR011128A1 (de)
AT (1) ATE294165T1 (de)
AU (1) AU6152598A (de)
BR (1) BR9807213A (de)
DE (1) DE69829956T2 (de)
EA (1) EA001784B1 (de)
ES (1) ES2239798T3 (de)
HR (1) HRP980056A2 (de)
SK (1) SK108999A3 (de)
TW (1) TW480253B (de)
WO (1) WO1998034928A1 (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6015926A (en) * 1997-05-16 2000-01-18 Merck & Co., Inc. Efficient enantioselective addition reaction using an organozinc reagent
PE20060587A1 (es) * 2004-09-02 2006-07-09 Bristol Myers Squibb Co Sintesis de (s)-6-cloro-4-ciclopropiletinil-4-trifluorometil-1,4-dihidro-2h-3,1-benzoxazin-2-ona

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5633405A (en) * 1995-05-25 1997-05-27 Merck & Co., Inc. Asymmetric synthesis of (-)-6-chloro-4-cyclopropyl-ethynyl-4-trifluoromethyl-1,4-dihydro-2H-3,1-benzoxanzin-2-one

Also Published As

Publication number Publication date
EA199900736A1 (ru) 2000-02-28
EP0968197B1 (de) 2005-04-27
AU6152598A (en) 1998-08-26
TW480253B (en) 2002-03-21
SK108999A3 (en) 2000-05-16
ES2239798T3 (es) 2005-10-01
DE69829956T2 (de) 2006-03-02
WO1998034928A1 (en) 1998-08-13
AR011128A1 (es) 2000-08-02
DE69829956D1 (de) 2005-06-02
CN1246852A (zh) 2000-03-08
HRP980056A2 (en) 1998-12-31
CN1073992C (zh) 2001-10-31
BR9807213A (pt) 2000-05-23
EA001784B1 (ru) 2001-08-27
EP0968197A1 (de) 2000-01-05

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Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties