ATE2951T1 - Verfahren zur herstellung von 3-dimethylamino-1phenyl-1-(m-chlorophenyl)propan-2-ol und zwischenprodukt fuer dieses verfahren. - Google Patents

Verfahren zur herstellung von 3-dimethylamino-1phenyl-1-(m-chlorophenyl)propan-2-ol und zwischenprodukt fuer dieses verfahren.

Info

Publication number: ATE2951T1
Authority: AT; Austria
Prior art keywords: chlorophenyl; propan; dimethylamino; preparation; 1phenyl
Prior art date: 1979-06-14

Application number

AT80301682T

Other languages

English (en)

Inventor

Paul Smith

Original Assignee

Beecham Group Plc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1979-06-14

Filing date

1980-05-20

Publication date

1983-04-15

1980-05-20 Application filed by Beecham Group Plc filed Critical Beecham Group Plc

1983-04-15 Application granted granted Critical

1983-04-15 Publication of ATE2951T1 publication Critical patent/ATE2951T1/de

Links

238000000034 method Methods 0.000 title abstract 3
KGSABFQIAANNPS-UHFFFAOYSA-N 1-(3-chlorophenyl)-3-(dimethylamino)-1-phenylpropan-2-ol Chemical compound C=1C=CC(Cl)=CC=1C(C(O)CN(C)C)C1=CC=CC=C1 KGSABFQIAANNPS-UHFFFAOYSA-N 0.000 title abstract 2
VTUJIMSRSFGMDR-UHFFFAOYSA-N 1-(3-chlorophenyl)-3-nitro-1-phenylpropan-2-ol Chemical compound C=1C=CC(Cl)=CC=1C(C(C[N+]([O-])=O)O)C1=CC=CC=C1 VTUJIMSRSFGMDR-UHFFFAOYSA-N 0.000 abstract 1
IHRJKAIHIIAWAZ-UHFFFAOYSA-N 2-(3-chlorophenyl)-2-phenylacetaldehyde Chemical compound ClC1=CC=CC(C(C=O)C=2C=CC=CC=2)=C1 IHRJKAIHIIAWAZ-UHFFFAOYSA-N 0.000 abstract 1
239000007868 Raney catalyst Substances 0.000 abstract 1
NPXOKRUENSOPAO-UHFFFAOYSA-N Raney nickel Chemical compound [Al].[Ni] NPXOKRUENSOPAO-UHFFFAOYSA-N 0.000 abstract 1
229910000564 Raney nickel Inorganic materials 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
LYGJENNIWJXYER-UHFFFAOYSA-N nitromethane Chemical compound C[N+]([O-])=O LYGJENNIWJXYER-UHFFFAOYSA-N 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
- C07C205/13—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by hydroxy groups
- C07C205/26—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by hydroxy groups and being further substituted by halogen atoms

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
Non-Silver Salt Photosensitive Materials And Non-Silver Salt Photography (AREA)

AT80301682T 1979-06-14 1980-05-20 Verfahren zur herstellung von 3-dimethylamino-1phenyl-1-(m-chlorophenyl)propan-2-ol und zwischenprodukt fuer dieses verfahren. ATE2951T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GB7920746		1979-06-14
EP80301682A EP0022310B1 (de)	1979-06-14	1980-05-20	Verfahren zur Herstellung von 3-Dimethylamino-1-phenyl-1-(m-chlorophenyl)propan-2-ol und Zwischenprodukt für dieses Verfahren

Publications (1)

Publication Number	Publication Date
ATE2951T1 true ATE2951T1 (de)	1983-04-15

Family

ID=10505848

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT80301682T ATE2951T1 (de)	1979-06-14	1980-05-20	Verfahren zur herstellung von 3-dimethylamino-1phenyl-1-(m-chlorophenyl)propan-2-ol und zwischenprodukt fuer dieses verfahren.

Country Status (15)

Country	Link
US (1)	US4327228A (de)
EP (1)	EP0022310B1 (de)
JP (1)	JPS565446A (de)
AT (1)	ATE2951T1 (de)
AU (1)	AU5926080A (de)
DE (1)	DE3062599D1 (de)
DK (1)	DK252480A (de)
ES (1)	ES492369A0 (de)
GR (1)	GR68470B (de)
IE (1)	IE49907B1 (de)
IL (1)	IL60174A0 (de)
NZ (1)	NZ193813A (de)
PH (1)	PH14982A (de)
PT (1)	PT71370A (de)
ZA (1)	ZA803016B (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JP2524814B2 (ja) *	1988-08-25	1996-08-14	キッセイ薬品工業株式会社	α―ヒドロキシ―β―アミノ酸の製造方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DD83574A (de) *
US1356877A (en) *	1916-04-01	1920-10-26	Dick Bunnell M	Mydriatic and process of making same
US1973647A (en) *	1929-08-06	1934-09-11	Nagai Alexander	Process of synthetically producing ephedrin homologue and its salts
US3431272A (en) *	1967-03-14	1969-03-04	Smithkline Corp	Dioxa-diazadispiro(4.2.4.2)tetradecane compounds
BE793469A (fr) *	1971-12-29	1973-06-28	Wellcome Found	Composes trypanocides
US3859354A (en) *	1972-12-26	1975-01-07	Lilly Co Eli	Preparation of 1-methyl-3,3-diphenyl-4-hydroxyhexylamine salts and o-acyl derivatives thereof
GB1443441A (en) *	1973-02-24	1976-07-21	Beecham Group Ltd	Pharmaceutical compositions comprising diphenylpropanolamine deri vatives

1980
- 1980-01-13 PH PH24130A patent/PH14982A/en unknown
- 1980-05-20 AT AT80301682T patent/ATE2951T1/de not_active IP Right Cessation
- 1980-05-20 DE DE8080301682T patent/DE3062599D1/de not_active Expired
- 1980-05-20 EP EP80301682A patent/EP0022310B1/de not_active Expired
- 1980-05-21 ZA ZA00803016A patent/ZA803016B/xx unknown
- 1980-05-22 NZ NZ193813A patent/NZ193813A/xx unknown
- 1980-05-27 GR GR62055A patent/GR68470B/el unknown
- 1980-05-27 IL IL60174A patent/IL60174A0/xx unknown
- 1980-06-03 US US06/156,189 patent/US4327228A/en not_active Expired - Lifetime
- 1980-06-11 PT PT71370A patent/PT71370A/pt unknown
- 1980-06-11 DK DK252480A patent/DK252480A/da unknown
- 1980-06-12 JP JP7957280A patent/JPS565446A/ja active Pending
- 1980-06-12 AU AU59260/80A patent/AU5926080A/en not_active Abandoned
- 1980-06-12 ES ES492369A patent/ES492369A0/es active Granted
- 1980-06-13 IE IE1222/80A patent/IE49907B1/en unknown

Also Published As

Publication number	Publication date
AU5926080A (en)	1980-12-18
JPS565446A (en)	1981-01-20
EP0022310A2 (de)	1981-01-14
ES8105695A1 (es)	1981-06-16
ES492369A0 (es)	1981-06-16
GR68470B (de)	1982-01-04
DK252480A (da)	1980-12-15
PT71370A (en)	1980-07-01
IL60174A0 (en)	1980-07-31
PH14982A (en)	1982-03-05
ZA803016B (en)	1981-03-25
DE3062599D1 (en)	1983-05-11
EP0022310B1 (de)	1983-04-06
EP0022310A3 (en)	1981-01-28
US4327228A (en)	1982-04-27
IE49907B1 (en)	1986-01-08
NZ193813A (en)	1982-05-25
IE801222L (en)	1980-12-14

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Legal Events

Date	Code	Title	Description
1983-06-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties