ES8105695A1 - Un procedimiento para la preparacion de 3-dimetilamino-1-fe-nil-1-(m-clorofenil)-propan-2-ol - Google Patents
Un procedimiento para la preparacion de 3-dimetilamino-1-fe-nil-1-(m-clorofenil)-propan-2-olInfo
- Publication number
- ES8105695A1 ES8105695A1 ES492369A ES492369A ES8105695A1 ES 8105695 A1 ES8105695 A1 ES 8105695A1 ES 492369 A ES492369 A ES 492369A ES 492369 A ES492369 A ES 492369A ES 8105695 A1 ES8105695 A1 ES 8105695A1
- Authority
- ES
- Spain
- Prior art keywords
- propan
- chlorophenyl
- phenyl
- dimethylamino
- preparation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- KGSABFQIAANNPS-UHFFFAOYSA-N 1-(3-chlorophenyl)-3-(dimethylamino)-1-phenylpropan-2-ol Chemical compound C=1C=CC(Cl)=CC=1C(C(O)CN(C)C)C1=CC=CC=C1 KGSABFQIAANNPS-UHFFFAOYSA-N 0.000 title abstract 2
- VTUJIMSRSFGMDR-UHFFFAOYSA-N 1-(3-chlorophenyl)-3-nitro-1-phenylpropan-2-ol Chemical compound C=1C=CC(Cl)=CC=1C(C(C[N+]([O-])=O)O)C1=CC=CC=C1 VTUJIMSRSFGMDR-UHFFFAOYSA-N 0.000 abstract 1
- 239000007868 Raney catalyst Substances 0.000 abstract 1
- NPXOKRUENSOPAO-UHFFFAOYSA-N Raney nickel Chemical compound [Al].[Ni] NPXOKRUENSOPAO-UHFFFAOYSA-N 0.000 abstract 1
- 229910000564 Raney nickel Inorganic materials 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
- C07C205/13—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by hydroxy groups
- C07C205/26—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by hydroxy groups and being further substituted by halogen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Non-Silver Salt Photosensitive Materials And Non-Silver Salt Photography (AREA)
- Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
PROCEDIMIENTO PARA LA OBTENCION DE 3-DIMETILAMINO-1FENIL-1-(M-CLOROFENIL)-PROPAN-2-OL, O SUS SALES. SE HACE REACCIONAR 3-NITRO-1-FENIL-1-(M-CLOROFENIL)-PROPAN-2-OL, DISUELTO EN UN ALCANOL C1-4, CON HIDROGENO A PRESION DE 6,8 A 27,2 ATM., ENTRE O Y 120 GC, UTILIZANDO NIQUEL RANEY COMO CATALIZADOR. SE DIMETILA LA AMINA OBTENIDA POR UN METODO CONVENCIONAL Y, EVENTUALMENTE, SE TRATA CON ACIDO PARA OBTENER LA SAL. TIENE APLICACION FARMACOLOGICA COMO AGENTE MODIFICADOR DEL HUMOR.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB7920746 | 1979-06-14 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES492369A0 ES492369A0 (es) | 1981-06-16 |
| ES8105695A1 true ES8105695A1 (es) | 1981-06-16 |
Family
ID=10505848
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES492369A Expired ES8105695A1 (es) | 1979-06-14 | 1980-06-12 | Un procedimiento para la preparacion de 3-dimetilamino-1-fe-nil-1-(m-clorofenil)-propan-2-ol |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US4327228A (es) |
| EP (1) | EP0022310B1 (es) |
| JP (1) | JPS565446A (es) |
| AT (1) | ATE2951T1 (es) |
| AU (1) | AU5926080A (es) |
| DE (1) | DE3062599D1 (es) |
| DK (1) | DK252480A (es) |
| ES (1) | ES8105695A1 (es) |
| GR (1) | GR68470B (es) |
| IE (1) | IE49907B1 (es) |
| IL (1) | IL60174A0 (es) |
| NZ (1) | NZ193813A (es) |
| PH (1) | PH14982A (es) |
| PT (1) | PT71370A (es) |
| ZA (1) | ZA803016B (es) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2524814B2 (ja) * | 1988-08-25 | 1996-08-14 | キッセイ薬品工業株式会社 | α―ヒドロキシ―β―アミノ酸の製造方法 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DD83574A (es) * | ||||
| US1356877A (en) * | 1916-04-01 | 1920-10-26 | Dick Bunnell M | Mydriatic and process of making same |
| US1973647A (en) * | 1929-08-06 | 1934-09-11 | Nagai Alexander | Process of synthetically producing ephedrin homologue and its salts |
| US3431272A (en) * | 1967-03-14 | 1969-03-04 | Smithkline Corp | Dioxa-diazadispiro(4.2.4.2)tetradecane compounds |
| BE793469A (fr) * | 1971-12-29 | 1973-06-28 | Wellcome Found | Composes trypanocides |
| PH11358A (en) * | 1972-12-26 | 1977-11-02 | Lilly Co Eli | Preparation of 1-methyl-3,3-diphenyl-4-hydroxylamine salts and o-acyl derivatives thereof |
| GB1443441A (en) * | 1973-02-24 | 1976-07-21 | Beecham Group Ltd | Pharmaceutical compositions comprising diphenylpropanolamine deri vatives |
-
1980
- 1980-01-13 PH PH24130A patent/PH14982A/en unknown
- 1980-05-20 DE DE8080301682T patent/DE3062599D1/de not_active Expired
- 1980-05-20 EP EP80301682A patent/EP0022310B1/en not_active Expired
- 1980-05-20 AT AT80301682T patent/ATE2951T1/de not_active IP Right Cessation
- 1980-05-21 ZA ZA00803016A patent/ZA803016B/xx unknown
- 1980-05-22 NZ NZ193813A patent/NZ193813A/xx unknown
- 1980-05-27 IL IL60174A patent/IL60174A0/xx unknown
- 1980-05-27 GR GR62055A patent/GR68470B/el unknown
- 1980-06-03 US US06/156,189 patent/US4327228A/en not_active Expired - Lifetime
- 1980-06-11 PT PT71370A patent/PT71370A/pt unknown
- 1980-06-11 DK DK252480A patent/DK252480A/da unknown
- 1980-06-12 JP JP7957280A patent/JPS565446A/ja active Pending
- 1980-06-12 ES ES492369A patent/ES8105695A1/es not_active Expired
- 1980-06-12 AU AU59260/80A patent/AU5926080A/en not_active Abandoned
- 1980-06-13 IE IE1222/80A patent/IE49907B1/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP0022310A2 (en) | 1981-01-14 |
| DK252480A (da) | 1980-12-15 |
| AU5926080A (en) | 1980-12-18 |
| PT71370A (en) | 1980-07-01 |
| EP0022310A3 (en) | 1981-01-28 |
| DE3062599D1 (en) | 1983-05-11 |
| EP0022310B1 (en) | 1983-04-06 |
| ES492369A0 (es) | 1981-06-16 |
| JPS565446A (en) | 1981-01-20 |
| IL60174A0 (en) | 1980-07-31 |
| PH14982A (en) | 1982-03-05 |
| IE801222L (en) | 1980-12-14 |
| ZA803016B (en) | 1981-03-25 |
| NZ193813A (en) | 1982-05-25 |
| ATE2951T1 (de) | 1983-04-15 |
| IE49907B1 (en) | 1986-01-08 |
| US4327228A (en) | 1982-04-27 |
| GR68470B (es) | 1982-01-04 |
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