|
US5795737A
(en)
*
|
1994-09-19 |
1998-08-18 |
The General Hospital Corporation |
High level expression of proteins
|
|
US5874304A
(en)
*
|
1996-01-18 |
1999-02-23 |
University Of Florida Research Foundation, Inc. |
Humanized green fluorescent protein genes and methods
|
|
US6020192A
(en)
*
|
1996-01-18 |
2000-02-01 |
University Of Florida |
Humanized green fluorescent protein genes and methods
|
|
US6541197B2
(en)
*
|
1996-01-22 |
2003-04-01 |
Human Gene Therapy Research Institute |
Vehicles for stable transfer of green fluorescent protein gene and methods of use for same
|
|
AR006928A1
(es)
*
|
1996-05-01 |
1999-09-29 |
Pioneer Hi Bred Int |
Una molecula de adn aislada que codifica una proteina fluorescente verde como marcador rastreable para la transformacion de plantas, un metodo para laproduccion de plantas transgenicas, un vector de expresion, una planta transgenica y celulas de dichas plantas.
|
|
US6593135B2
(en)
|
1996-08-16 |
2003-07-15 |
The State Of Oregon, Acting By And Through The State Board Of Higher Education On Behalf Of The University Of Oregon |
Long wavelength engineered fluorescent proteins
|
|
US6124128A
(en)
|
1996-08-16 |
2000-09-26 |
The Regents Of The University Of California |
Long wavelength engineered fluorescent proteins
|
|
US6114148C1
(en)
*
|
1996-09-20 |
2012-05-01 |
Gen Hospital Corp |
High level expression of proteins
|
|
US6245564B1
(en)
|
1997-01-23 |
2001-06-12 |
Cornell Research Foundation, Inc. |
Method for separating cells
|
|
US6670449B1
(en)
|
1997-02-13 |
2003-12-30 |
Memorial Sloan-Kettering Cancer Center |
Hybrid molecules and their use for optically detecting changes in cellular microenvironments
|
|
WO1998045704A2
(en)
*
|
1997-04-07 |
1998-10-15 |
Bioimage A/S |
A method for extracting quantitative information relating to an influence on a cellular response
|
|
US6046925A
(en)
*
|
1997-04-14 |
2000-04-04 |
The Regents Of The University Of California |
Photochromic fluorescent proteins and optical memory storage devices based on fluorescent proteins
|
|
US6528307B1
(en)
*
|
1997-04-25 |
2003-03-04 |
The Wistar Institute Of Anatomy And Biology |
Cytolytic T-cell clones against colorectal carcinoma
|
|
US6251384B1
(en)
*
|
1997-04-28 |
2001-06-26 |
Anticancer, Inc. |
Metastasis models using green fluorescent protein (GFP) as a marker
|
|
US6232523B1
(en)
*
|
1997-04-28 |
2001-05-15 |
Anticancer, Inc. |
Metastasis models using green fluorescent protein (GFP) as a marker
|
|
US7541151B2
(en)
|
1997-06-05 |
2009-06-02 |
Duke University |
Single-cell biosensor for the measurement of GPCR ligands in a test sample
|
|
US6528271B1
(en)
*
|
1997-06-05 |
2003-03-04 |
Duke University |
Inhibition of βarrestin mediated effects prolongs and potentiates opioid receptor-mediated analgesia
|
|
US5891646A
(en)
*
|
1997-06-05 |
1999-04-06 |
Duke University |
Methods of assaying receptor activity and constructs useful in such methods
|
|
CA2296067C
(en)
*
|
1997-07-09 |
2008-10-07 |
The University Of Queensland |
Nucleic acid sequence and method for selectively expressing a protein in a target cell or tissue
|
|
AUPP807899A0
(en)
|
1999-01-08 |
1999-02-04 |
University Of Queensland, The |
Codon utilization
|
|
US6602677B1
(en)
*
|
1997-09-19 |
2003-08-05 |
Promega Corporation |
Thermostable luciferases and methods of production
|
|
US6130313A
(en)
*
|
1997-10-02 |
2000-10-10 |
Clontech Laboratories, Inc. |
Rapidly degrading GFP-fusion proteins
|
|
JP3736617B2
(ja)
*
|
1997-12-12 |
2006-01-18 |
ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア |
細胞型の決定方法
|
|
DE19811618C1
(de)
|
1998-03-17 |
2000-08-31 |
Andreas Jenne |
Ribozym codierende DNA und ein Oligonucleotidsubstrat enthaltende Zusammensetzung und Verfahren zur Messung von Transkriptionsraten
|
|
WO1999049041A1
(en)
*
|
1998-03-26 |
1999-09-30 |
The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Drm, a secreted protein with cell growth inhibiting activity, and related methods and compositions
|
|
EP1925320A3
(de)
|
1998-03-27 |
2008-09-03 |
Prolume, Ltd. |
Luciferasen, fluoreszierende Proteine, Nukleinsäuren zur Kodierung der Luciferasen und der fluoreszierenden Proteine sowie deren Verwendung zur Diagnose, zum Screening mit hohem Durchsatz und zur Behandlung neuartiger Probleme
|
|
AU765703B2
(en)
|
1998-03-27 |
2003-09-25 |
Bruce J. Bryan |
Luciferases, fluorescent proteins, nucleic acids encoding the luciferases and fluorescent proteins and the use thereof in diagnostics, high throughput screening and novelty items
|
|
FR2778408A1
(fr)
*
|
1998-05-11 |
1999-11-12 |
Univ Pasteur |
Anticorps recombinants fluorescents
|
|
US7090976B2
(en)
*
|
1999-11-10 |
2006-08-15 |
Rigel Pharmaceuticals, Inc. |
Methods and compositions comprising Renilla GFP
|
|
GB9810752D0
(en)
*
|
1998-05-19 |
1998-07-15 |
Glaxo Group Ltd |
Cystosine deaminase gene
|
|
US6509174B2
(en)
*
|
1998-06-16 |
2003-01-21 |
Ecole Polytechnique Federal De Lausanne (Epfl) |
Cells, genetically modified with optical marker
|
|
US6924365B1
(en)
|
1998-09-29 |
2005-08-02 |
Transkaryotic Therapies, Inc. |
Optimized messenger RNA
|
|
US8263402B1
(en)
|
1998-10-19 |
2012-09-11 |
Cornell Research Foundation, Inc. |
Method for isolating and purifying oligodendrocytes and oligodendrocyte progenitor cells
|
|
US6759237B1
(en)
*
|
1998-11-05 |
2004-07-06 |
The Trustees Of The University Of Pennsylvania |
Adeno-associated virus serotype 1 nucleic acid sequences, vectors and host cells containing same
|
|
EP1135468B1
(de)
|
1998-11-10 |
2010-01-06 |
University Of North Carolina At Chapel Hill |
Virusvektoren und verfahren für ihre herstellung und verabreichung.
|
|
US9834584B2
(en)
*
|
1998-12-11 |
2017-12-05 |
Takara Bio Usa, Inc. |
Nucleic acids encoding chromophores/fluorophores and methods for using the same
|
|
US20030087492A1
(en)
|
2001-11-02 |
2003-05-08 |
Promos Technologies, Inc. |
Semiconductor device and method of manufacturing the same
|
|
US7338785B2
(en)
|
1998-12-11 |
2008-03-04 |
Clontech Laboratories, Inc. |
Nucleic acids encoding chromophores/fluorophores and methods for using the same
|
|
AUPP807799A0
(en)
*
|
1999-01-08 |
1999-02-04 |
University Of Queensland, The |
Polynucleotide and method
|
|
US8406498B2
(en)
|
1999-01-25 |
2013-03-26 |
Amnis Corporation |
Blood and cell analysis using an imaging flow cytometer
|
|
US8131053B2
(en)
|
1999-01-25 |
2012-03-06 |
Amnis Corporation |
Detection of circulating tumor cells using imaging flow cytometry
|
|
US7450229B2
(en)
|
1999-01-25 |
2008-11-11 |
Amnis Corporation |
Methods for analyzing inter-cellular phenomena
|
|
US8885913B2
(en)
|
1999-01-25 |
2014-11-11 |
Amnis Corporation |
Detection of circulating tumor cells using imaging flow cytometry
|
|
WO2000050633A1
(en)
*
|
1999-02-24 |
2000-08-31 |
The General Hospital Corporation |
Method for cloning signal transduction intermediates
|
|
DE19915137C2
(de)
*
|
1999-03-26 |
2001-10-18 |
Michael Schaefer |
Verfahren zur Quantifizierung mehrerer Fluorochrome in einer mehrfach gefärbten Probe bei der Fluoreszenzmikroskopie und Verwendungen des Verfahrens
|
|
US6541244B1
(en)
*
|
1999-06-07 |
2003-04-01 |
Cedars-Sinai Medical Center |
Suppressor of cytokine signaling (SOCS)-3 promoter and methods for its use in genetic therapy in humans
|
|
US20050005310A1
(en)
*
|
1999-07-12 |
2005-01-06 |
Genentech, Inc. |
Expression vectors and methods
|
|
DE60025829T2
(de)
*
|
1999-07-12 |
2006-11-02 |
Genentech, Inc., South San Francisco |
Expressionsvektoren und anwendungsmethoden
|
|
US7001995B1
(en)
*
|
1999-08-25 |
2006-02-21 |
Merck & Co., Inc. |
Synthetic human papillomavirus genes
|
|
US6716614B1
(en)
*
|
1999-09-02 |
2004-04-06 |
Lexicon Genetics Incorporated |
Human calcium dependent proteases, polynucleotides encoding the same, and uses thereof
|
|
US6541252B1
(en)
|
2000-05-19 |
2003-04-01 |
Lexicon Genetics Incorporated |
Human kinases and polynucleotides encoding the same
|
|
US6864355B1
(en)
|
2000-05-02 |
2005-03-08 |
Yale University |
Inhibition of NF-κB activation by blockade of IKKβ-NEMO interactions at the NEMO binding domain
|
|
AU783767B2
(en)
|
1999-10-14 |
2005-12-01 |
Takara Bio Usa, Inc. |
Anthozoa derived chromophores/fluorophores and methods for using the same
|
|
EP1235857A1
(de)
*
|
1999-11-19 |
2002-09-04 |
Cold Spring Harbor Laboratory |
Transgene mäuse, die ein fluoreszenzmarkiertes protein exprimieren, das vom nestin-promoter kontrolliert wird
|
|
AU2913801A
(en)
*
|
1999-12-23 |
2001-07-03 |
Cornell Research Foundation Inc. |
A method for isolating and purifying multipotential neural progenitor cells and multipotential neural progenitor cells
|
|
US20020064842A1
(en)
*
|
2000-06-09 |
2002-05-30 |
Sorge Joseph A. |
Renilla reniformis green fluorescent protein and mutants thereof
|
|
US6502774B1
(en)
*
|
2000-03-08 |
2003-01-07 |
J + L Fiber Services, Inc. |
Refiner disk sensor and sensor refiner disk
|
|
US7109315B2
(en)
*
|
2000-03-15 |
2006-09-19 |
Bruce J. Bryan |
Renilla reniformis fluorescent proteins, nucleic acids encoding the fluorescent proteins and the use thereof in diagnostics, high throughput screening and novelty items
|
|
CA2301158A1
(en)
*
|
2000-03-24 |
2001-09-24 |
Stephen J. Allen |
Screening methods for compounds useful for modulating lipid metabolism in disease
|
|
US7037493B2
(en)
|
2000-05-01 |
2006-05-02 |
Cornell Research Foundation, Inc. |
Method of inducing neuronal production in the brain and spinal cord
|
|
US6656700B2
(en)
*
|
2000-05-26 |
2003-12-02 |
Amersham Plc |
Isoforms of human pregnancy-associated protein-E
|
|
US6686188B2
(en)
|
2000-05-26 |
2004-02-03 |
Amersham Plc |
Polynucleotide encoding a human myosin-like polypeptide expressed predominantly in heart and muscle
|
|
JP2002045174A
(ja)
*
|
2000-07-31 |
2002-02-12 |
Inst Of Physical & Chemical Res |
ナチュラルキラー細胞増殖法
|
|
KR100393709B1
(ko)
*
|
2000-08-07 |
2003-08-06 |
광주과학기술원 |
재조합 동물 세포주를 이용한 환경 오염 물질의 탐지 방법
|
|
KR100403159B1
(ko)
*
|
2000-08-07 |
2003-10-30 |
광주과학기술원 |
씨-포스 프로모터와 녹색 형광 단백질 유전자의 융합유전자, 이 유전자를 포함하는 벡터 및 이 벡터로형질감염된 재조합 동물 세포
|
|
JP2004267001A
(ja)
*
|
2000-08-16 |
2004-09-30 |
Kansai Tlo Kk |
トランスジェニック哺乳動物及びその作製方法並びにこれを用いた遺伝子機能の解明方法
|
|
US7879540B1
(en)
|
2000-08-24 |
2011-02-01 |
Promega Corporation |
Synthetic nucleic acid molecule compositions and methods of preparation
|
|
US20030157643A1
(en)
*
|
2000-08-24 |
2003-08-21 |
Almond Brian D |
Synthetic nucleic acids from aquatic species
|
|
US20040115659A1
(en)
*
|
2001-08-29 |
2004-06-17 |
Benjamin Geiger |
Methods of isolating genes encoding proteins of specific function and of screening for pharmaceutically active agents
|
|
US20020123474A1
(en)
*
|
2000-10-04 |
2002-09-05 |
Shannon Mark E. |
Human GTP-Rho binding protein2
|
|
US7157565B2
(en)
*
|
2000-10-12 |
2007-01-02 |
Clontech Laboratories, Inc. |
Far red shifted fluorescent proteins
|
|
EP1624062A3
(de)
*
|
2000-10-27 |
2006-02-22 |
Lexicon Genetics Incorporated |
Humane 7tm Proteine und dafür kodierende Polynukleotide
|
|
EP1330524A2
(de)
*
|
2000-10-30 |
2003-07-30 |
Lexicon Genetics Incorporated |
Humane 7tm-proteine und dafür kodierende polynukleotiden
|
|
US6645761B1
(en)
*
|
2000-12-22 |
2003-11-11 |
Stratagene |
Humanized polynucleotide sequence encoding Renilla mulleri green fluorescent protein
|
|
US6969597B2
(en)
*
|
2001-02-21 |
2005-11-29 |
Clontech Laboratories, Inc. |
Nucleic acids encoding non aggregating fluorescent proteins and methods for using the same
|
|
US20050079579A1
(en)
*
|
2001-02-28 |
2005-04-14 |
Guangwen Wei |
Uses of spatial configuration to modulate protein function
|
|
CN1245215C
(zh)
*
|
2001-02-28 |
2006-03-15 |
四川省生物工程研究中心 |
重组高效复合干扰素用作乙型肝炎表面抗原和e抗原抑制剂
|
|
US20060035327A1
(en)
*
|
2001-02-28 |
2006-02-16 |
Guangwen Wei |
Recombinant super-compound interferon and uses thereof
|
|
JP2004537280A
(ja)
*
|
2001-03-07 |
2004-12-16 |
ゼノジェン コーポレイション |
標的細胞中へのdnaの導入についてのスクリーニング方法
|
|
JP3929250B2
(ja)
*
|
2001-03-08 |
2007-06-13 |
株式会社ルネサステクノロジ |
半導体装置
|
|
US7015310B2
(en)
|
2001-03-12 |
2006-03-21 |
The State Of Oregon Acting By And Through The State Board Of Higher Education On Behalf Of The University Of Oregon |
Oxidation reduction sensitive green fluorescent protein variants
|
|
EP1390379A4
(de)
*
|
2001-05-25 |
2005-02-02 |
Clontech Lab Inc |
Kindling fluorescent proteine und verfahren zu deren anwendung
|
|
JP3829252B2
(ja)
|
2001-06-08 |
2006-10-04 |
独立行政法人理化学研究所 |
蛍光蛋白質
|
|
US6780974B2
(en)
*
|
2001-06-12 |
2004-08-24 |
Cellomics, Inc. |
Synthetic DNA encoding an orange seapen-derived green fluorescent protein with codon preference of mammalian expression systems and biosensors
|
|
US7393656B2
(en)
|
2001-07-10 |
2008-07-01 |
The Board Of Trustees Of The Leland Stanford Junior University |
Methods and compositions for risk stratification
|
|
EP1423537A4
(de)
*
|
2001-08-07 |
2006-11-29 |
Univ Delaware |
Zusammensetzungen und verfahren zur vorbeugung und behandlung von morbus huntington
|
|
US20040096880A1
(en)
*
|
2001-08-07 |
2004-05-20 |
Kmiec Eric B. |
Compositions and methods for the treatment of diseases exhibiting protein misassembly and aggregation
|
|
WO2003014320A2
(en)
|
2001-08-10 |
2003-02-20 |
Cornell Research Foundation, Inc. |
Telomerase immortalized human neutral stem cells and phenotypically-restricted progenitor cells
|
|
AR036370A1
(es)
*
|
2001-08-27 |
2004-09-01 |
Syngenta Participations Ag |
Plantas con auto-procesamiento y partes de las mismas
|
|
EP1575916B1
(de)
|
2001-08-31 |
2013-05-22 |
The Rockefeller University |
Phosphodiesteraseaktivität und regulation der durch phosphodiesterase-1-b vermittelten signalvermittlung im hirn
|
|
EP1434483B1
(de)
*
|
2001-10-12 |
2007-12-05 |
Clontech Laboratories, Inc. |
Nukleinsäuren kodierend miteinander verbundene chromo/fluoreszenzdomänen und verfahren zu ihrer verwendung
|
|
JP2005509420A
(ja)
*
|
2001-11-13 |
2005-04-14 |
クローンテック ラボラトリーズ インク. |
新規発色団/蛍光発色団およびそれらの使用法
|
|
WO2003054158A2
(en)
*
|
2001-12-19 |
2003-07-03 |
The University Of Chicago |
Rapidly maturing fluorescent proteins and methods for using the same
|
|
WO2003057833A2
(en)
*
|
2001-12-26 |
2003-07-17 |
Clontech Laboratories, Inc. |
Mutant chromophores/fluorophores and methods for making and using the same
|
|
AU2003209272A1
(en)
*
|
2002-01-16 |
2003-09-02 |
Zyomyx, Inc. |
Engineered binding proteins
|
|
DK1485481T3
(da)
*
|
2002-01-22 |
2010-06-07 |
Evrogen Ip |
Fflourescerende protein fra Aequorea Coerulescens og anvendelser deraf
|
|
US6918839B2
(en)
*
|
2002-01-28 |
2005-07-19 |
The Boeing Company |
Damage tolerant shaft
|
|
WO2003068357A2
(en)
*
|
2002-02-12 |
2003-08-21 |
Cornell Research Foundation, Inc. |
Identification and high-yield isolation of human pancreatic islet progenitor and stem cells
|
|
US7576065B2
(en)
*
|
2002-02-15 |
2009-08-18 |
Cornell Research Foundation, Inc. |
Enhancing neurotrophin-induced neurogenesis by endogenous neural progenitor cells by concurrent overexpression of brain derived neurotrophic factor and an inhibitor of a pro-gliogenic bone morphogenetic protein
|
|
US20100311954A1
(en)
*
|
2002-03-01 |
2010-12-09 |
Xencor, Inc. |
Optimized Proteins that Target Ep-CAM
|
|
AU2003228301A1
(en)
*
|
2002-03-06 |
2003-09-22 |
Rigel Pharmaceuticals, Inc. |
Novel method for delivery and intracellular synthesis of sirna molecules
|
|
US20030182669A1
(en)
*
|
2002-03-19 |
2003-09-25 |
Rockman Howard A. |
Phosphoinositide 3-kinase mediated inhibition of GPCRs
|
|
US7351542B2
(en)
|
2002-05-20 |
2008-04-01 |
The Regents Of The University Of California |
Methods of modulating tubulin deacetylase activity
|
|
US7290215B2
(en)
*
|
2002-06-03 |
2007-10-30 |
Microsoft Corporation |
Dynamic wizard interface system and method
|
|
EP1513929A4
(de)
*
|
2002-06-18 |
2006-04-19 |
Zymogenetics Inc |
Hybridvektor mit einem cytomegalovirus-enhancer und promotor des myeloproliferativen sarkom-virus
|
|
CA2492074A1
(en)
*
|
2002-07-10 |
2004-01-15 |
Stratagene |
Humanized renilla reniformis green fluorescent protein as a scaffold
|
|
US7018835B2
(en)
*
|
2002-08-20 |
2006-03-28 |
David Michael Hone |
Recombinant double-stranded RNA phage, and use of the same
|
|
WO2004024915A1
(en)
*
|
2002-09-13 |
2004-03-25 |
The University Of Queensland |
Gene expression system based on codon translation efficiency
|
|
US9453251B2
(en)
|
2002-10-08 |
2016-09-27 |
Pfenex Inc. |
Expression of mammalian proteins in Pseudomonas fluorescens
|
|
AU2003301883A1
(en)
*
|
2002-10-30 |
2004-06-07 |
University Of Tennessee Research Foundation |
Modified luciferase nucleic acids and methods of use
|
|
CA2505974A1
(en)
|
2002-11-12 |
2004-05-27 |
Zakrytoe Aktsionernoe Obschestvo "Evrogen" |
Fluorescent proteins and chromoproteins from non-aequorea hydrozoa species and methods for using same
|
|
US20050019925A1
(en)
*
|
2002-11-14 |
2005-01-27 |
Genentech, Inc. |
Intron fusion construct and method of using for selecting high-expressing production cell lines
|
|
DE10255852B4
(de)
*
|
2002-11-29 |
2006-06-22 |
Deutsches Institut für Ernährungsforschung |
Verfahren zur Expressionsveränderung von Polypeptiden in rekombinanten Expressionssystemen
|
|
US7413874B2
(en)
*
|
2002-12-09 |
2008-08-19 |
University Of Miami |
Nucleic acid encoding fluorescent proteins from aquatic species
|
|
CA2510884A1
(en)
|
2002-12-26 |
2004-07-15 |
Zakrytoe Aktsionernoe Obschestvo "Evrogen" |
Fluorescent proteins from copepoda species and methods for using same
|
|
US7083931B2
(en)
*
|
2003-04-04 |
2006-08-01 |
Stratagene California |
Renilla GFP mutants with increased fluorescent intensity and spectral shift
|
|
EP1624748A4
(de)
*
|
2003-05-08 |
2009-01-07 |
Health Research Inc |
Transgenes tiermodell für krebs- und stammzellen
|
|
WO2005019252A2
(en)
*
|
2003-05-22 |
2005-03-03 |
University Of Florida Research Foundation, Inc. |
Novel fluorescent and colored proteins, and polynucleotides that encode these proteins
|
|
EP1484410B1
(de)
*
|
2003-06-05 |
2011-11-02 |
Ajinomoto Co., Inc. |
Fermentierungsverfahren mittels veränderter Bakterien mit einer erhöhten Aufnahme von Nebenprodukten
|
|
JP4653103B2
(ja)
|
2003-06-10 |
2011-03-16 |
ザ ジェイ.ディヴィッド グラッドストン インスティテューツ |
レンチウイルス感染症を治療するための方法
|
|
KR100577512B1
(ko)
*
|
2003-06-16 |
2006-05-10 |
주식회사 바이오인프라 |
녹색 형광 단백질과 Bfl-1의 융합단백질 또는 이를코딩하는 유전자를 포함하는 세포사멸을 유도하기 위한약학 조성물
|
|
US20050037409A1
(en)
*
|
2003-07-29 |
2005-02-17 |
Kauvar Lawrence M. |
Translocation tagging
|
|
DE10336760A1
(de)
*
|
2003-08-08 |
2005-03-03 |
Axaron Bioscience Ag |
Verfahren zur in vivo-Markierung definierter Zelltypen innerhalb eines Gewebeverbands
|
|
AU2004269390A1
(en)
*
|
2003-08-28 |
2005-03-10 |
Huiyangtech (Usa), Inc. |
Uses of spatial configuration to modulate protein function
|
|
US7585647B2
(en)
*
|
2003-08-28 |
2009-09-08 |
Guangwen Wei |
Nucleic acid encoding recombinant interferon
|
|
DK1663110T3
(en)
*
|
2003-08-28 |
2014-03-24 |
Superlab Far East Ltd |
APPLICATIONS OF INTERFERONES WITH CHANGED SPACIAL STRUCTURE
|
|
US20060134105A1
(en)
*
|
2004-10-21 |
2006-06-22 |
Xencor, Inc. |
IgG immunoglobulin variants with optimized effector function
|
|
US8883147B2
(en)
|
2004-10-21 |
2014-11-11 |
Xencor, Inc. |
Immunoglobulins insertions, deletions, and substitutions
|
|
US8399618B2
(en)
|
2004-10-21 |
2013-03-19 |
Xencor, Inc. |
Immunoglobulin insertions, deletions, and substitutions
|
|
US7481997B1
(en)
|
2004-02-12 |
2009-01-27 |
Montana State University |
Snow mountain virus genome sequence, virus-like particles and methods of use
|
|
JP4572320B2
(ja)
*
|
2004-02-23 |
2010-11-04 |
財団法人大阪産業振興機構 |
組換えヒト細胞、ならびにその組換えヒト細胞を用いてヒト薬物代謝酵素の誘導および薬物代謝の少なくとも一方を評価する方法
|
|
WO2005098430A2
(en)
|
2004-03-16 |
2005-10-20 |
Amnis Corporation |
Image based quantitation of molecular translocation
|
|
US8953866B2
(en)
|
2004-03-16 |
2015-02-10 |
Amnis Corporation |
Method for imaging and differential analysis of cells
|
|
EP1732944B1
(de)
|
2004-04-07 |
2012-09-05 |
The University of Chicago |
Monomere, rotfluoreszierende proteine
|
|
US20050281786A1
(en)
*
|
2004-06-18 |
2005-12-22 |
David Poulsen |
AAV mediated gene delivery to cochlear cells
|
|
CN101031655A
(zh)
|
2004-07-26 |
2007-09-05 |
陶氏环球技术公司 |
通过株工程改进蛋白表达的方法
|
|
US7728118B2
(en)
*
|
2004-09-17 |
2010-06-01 |
Promega Corporation |
Synthetic nucleic acid molecule compositions and methods of preparation
|
|
US9200079B2
(en)
|
2004-11-12 |
2015-12-01 |
Xencor, Inc. |
Fc variants with altered binding to FcRn
|
|
US8802820B2
(en)
|
2004-11-12 |
2014-08-12 |
Xencor, Inc. |
Fc variants with altered binding to FcRn
|
|
EP1828390B1
(de)
*
|
2004-12-15 |
2012-06-13 |
The University Of North Carolina At Chapel Hill |
Chimäre vektoren
|
|
US7230080B2
(en)
*
|
2005-02-16 |
2007-06-12 |
University Of Florida Research Foundation, Inc. |
Fluorescent and colored proteins, and polynucleotides that encode these proteins
|
|
TWI380993B
(zh)
*
|
2005-03-09 |
2013-01-01 |
輝陽科技美國公司 |
重組型超化合物干擾素之用途
|
|
WO2007008943A2
(en)
|
2005-07-08 |
2007-01-18 |
Xencor, Inc. |
Optimized anti-ep-cam antibodies
|
|
EP1931787A4
(de)
*
|
2005-09-30 |
2010-10-20 |
Univ Montana State |
System zum nachweis von protein-protein-wechselwirkungen
|
|
WO2007041350A2
(en)
*
|
2005-10-01 |
2007-04-12 |
Charles Stout |
Regulatable fusion promoters
|
|
EP1954713B1
(de)
|
2005-11-04 |
2012-11-14 |
Evrogen, JSC |
Modifizierte grünfluoreszierende proteine und verfahren zu deren anwendung
|
|
ATE516370T1
(de)
*
|
2005-12-22 |
2011-07-15 |
Sloan Kettering Inst Cancer |
Verfahren zur erfassung von krebszellen unter verwendung eines virus
|
|
EP1989303A2
(de)
*
|
2006-02-27 |
2008-11-12 |
Edenspace System Corporation |
Energiepflanzen für verbessertes biokraftstoffrohmaterial
|
|
CA2657975A1
(en)
*
|
2006-06-29 |
2008-01-03 |
Dsm Ip Assets B.V. |
A method for achieving improved polypeptide expression
|
|
US20080004410A1
(en)
*
|
2006-06-30 |
2008-01-03 |
Yu-Chin Lai |
Hydrophilic macromonomers having alpha,beta-conjugated carboxylic terminal group and medical devices incorporating same
|
|
EP3796002B1
(de)
|
2006-07-14 |
2023-11-22 |
The Regents of The University of California |
Krebsbiomarker und verfahren zur verwendung davon
|
|
US8680235B2
(en)
*
|
2006-09-22 |
2014-03-25 |
Stowers Institute For Medical Research |
Branchiostoma derived fluorescent proteins
|
|
US7767206B2
(en)
|
2006-10-02 |
2010-08-03 |
Amgen Inc. |
Neutralizing determinants of IL-17 Receptor A and antibodies that bind thereto
|
|
US9043994B2
(en)
*
|
2007-03-13 |
2015-06-02 |
Massachusetts Institute Of Technology |
Cre-lox based gene knockdown constructs and methods of use thereof
|
|
US20080248511A1
(en)
*
|
2007-03-26 |
2008-10-09 |
Promega Corporation |
Methods to quench light from optical reactions
|
|
US9580719B2
(en)
|
2007-04-27 |
2017-02-28 |
Pfenex, Inc. |
Method for rapidly screening microbial hosts to identify certain strains with improved yield and/or quality in the expression of heterologous proteins
|
|
US9394571B2
(en)
|
2007-04-27 |
2016-07-19 |
Pfenex Inc. |
Method for rapidly screening microbial hosts to identify certain strains with improved yield and/or quality in the expression of heterologous proteins
|
|
EP2860247A1
(de)
|
2007-08-21 |
2015-04-15 |
Nodality, Inc. |
Diagnose-, Prognose- und Behandlungsverfahren
|
|
JP5718640B2
(ja)
|
2007-08-21 |
2015-05-13 |
アムジエン・インコーポレーテツド |
ヒトc−fms抗原結合性タンパク質
|
|
US20090081715A1
(en)
*
|
2007-09-07 |
2009-03-26 |
Cobalt Technologies, Inc., A Delaware Corporation |
Engineered Light-Emitting Reporter Genes
|
|
TW200918553A
(en)
|
2007-09-18 |
2009-05-01 |
Amgen Inc |
Human GM-CSF antigen binding proteins
|
|
CN104297506B
(zh)
|
2007-10-02 |
2017-05-03 |
赛拉诺斯股份有限公司 |
模块化现场护理装置及其应用
|
|
US8679749B2
(en)
*
|
2007-11-01 |
2014-03-25 |
The University Of Chicago |
Red fluorescent proteins with enhanced bacterial expression, increased brightness and reduced aggregation
|
|
KR101616758B1
(ko)
|
2007-12-26 |
2016-04-29 |
젠코어 인코포레이티드 |
FcRn에 대한 변경된 결합성을 갖는 Fc 변이체
|
|
CA2721076A1
(en)
|
2008-04-09 |
2009-10-15 |
Cobalt Technologies, Inc. |
Immobilized product tolerant microorganisms
|
|
US8309306B2
(en)
*
|
2008-11-12 |
2012-11-13 |
Nodality, Inc. |
Detection composition
|
|
JO3382B1
(ar)
|
2008-12-23 |
2019-03-13 |
Amgen Inc |
أجسام مضادة ترتبط مع مستقبل cgrp بشري
|
|
JP5304275B2
(ja)
*
|
2009-01-29 |
2013-10-02 |
Jnc株式会社 |
アポクライティン−iiをコードするコドン最適化核酸およびその使用方法
|
|
US20100233733A1
(en)
*
|
2009-02-10 |
2010-09-16 |
Nodality, Inc., A Delaware Corporation |
Multiple mechanisms for modulation of the pi3 kinase pathway
|
|
EP2396343B1
(de)
|
2009-02-11 |
2017-05-17 |
The University of North Carolina At Chapel Hill |
Modifizierte virusvektoren sowie verfahren zu ihrer herstellung und verwendung
|
|
US20120058523A1
(en)
|
2009-02-17 |
2012-03-08 |
Edenspace Systems Corporation |
Tempering of cellulosic biomass
|
|
US8242248B2
(en)
*
|
2009-03-23 |
2012-08-14 |
Nodality, Inc. |
Kits for multiparametric phospho analysis
|
|
JP5822822B2
(ja)
|
2009-04-17 |
2015-11-24 |
ニューヨーク ユニバーシティ |
Tnfファミリー受容体を標的とし、tnf作用を拮抗するペプチド、その組成物、方法および使用
|
|
TWI372183B
(en)
*
|
2009-05-05 |
2012-09-11 |
Nat Univ Tsing Hua |
Utilizing shield effect for dopamine detection and reagent development
|
|
WO2010138971A1
(en)
|
2009-05-29 |
2010-12-02 |
Edenspace Systems Corporation |
Plant gene regulatory elements
|
|
MX2011013974A
(es)
|
2009-06-26 |
2012-04-30 |
Cobalt Technologies Inc |
Sistema y proceso integrados para la produccion de bioproductos.
|
|
TW201117824A
(en)
|
2009-10-12 |
2011-06-01 |
Amgen Inc |
Use of IL-17 receptor a antigen binding proteins
|
|
UA109888C2
(uk)
|
2009-12-07 |
2015-10-26 |
|
ІЗОЛЬОВАНЕ АНТИТІЛО АБО ЙОГО ФРАГМЕНТ, ЩО ЗВ'ЯЗУЄТЬСЯ З β-КЛОТО, РЕЦЕПТОРАМИ FGF І ЇХНІМИ КОМПЛЕКСАМИ
|
|
WO2011130417A2
(en)
|
2010-04-15 |
2011-10-20 |
Amgen Inc. |
HUMAN FGF RECEPTOR AND β-KLOTHO BINDING PROTEINS
|
|
EP2564200B8
(de)
|
2010-04-27 |
2019-10-02 |
The Regents of The University of California |
Krebsbiomarker und anwendungsverfahren dafür
|
|
CA2798703A1
(en)
|
2010-05-10 |
2011-11-17 |
The Regents Of The University Of California |
Endoribonuclease compositions and methods of use thereof
|
|
FR2961375B1
(fr)
|
2010-06-16 |
2016-05-13 |
Inst De Rech Pour Le Dev (Ird) |
Surproduction d'acide jasmonique dans des plantes transgeniques
|
|
WO2012030738A2
(en)
|
2010-08-30 |
2012-03-08 |
Beckman Coulter, Inc. |
Complex phosphoprotein activation profiles
|
|
CN103477197B
(zh)
|
2011-01-21 |
2016-08-17 |
提拉诺斯公司 |
样品使用最大化的系统和方法
|
|
WO2012155071A1
(en)
|
2011-05-12 |
2012-11-15 |
Gilead Biologics, Inc. |
Methods of identifying lysyl oxidase - like - 2 (loxl2) binding partners
|
|
US9574002B2
(en)
|
2011-06-06 |
2017-02-21 |
Amgen Inc. |
Human antigen binding proteins that bind to a complex comprising β-Klotho and an FGF receptor
|
|
US20140234330A1
(en)
|
2011-07-22 |
2014-08-21 |
Amgen Inc. |
Il-17 receptor a is required for il-17c biology
|
|
US8475739B2
(en)
|
2011-09-25 |
2013-07-02 |
Theranos, Inc. |
Systems and methods for fluid handling
|
|
US20140170735A1
(en)
|
2011-09-25 |
2014-06-19 |
Elizabeth A. Holmes |
Systems and methods for multi-analysis
|
|
US9268915B2
(en)
|
2011-09-25 |
2016-02-23 |
Theranos, Inc. |
Systems and methods for diagnosis or treatment
|
|
US8840838B2
(en)
|
2011-09-25 |
2014-09-23 |
Theranos, Inc. |
Centrifuge configurations
|
|
US9632102B2
(en)
|
2011-09-25 |
2017-04-25 |
Theranos, Inc. |
Systems and methods for multi-purpose analysis
|
|
US8435738B2
(en)
|
2011-09-25 |
2013-05-07 |
Theranos, Inc. |
Systems and methods for multi-analysis
|
|
US9664702B2
(en)
|
2011-09-25 |
2017-05-30 |
Theranos, Inc. |
Fluid handling apparatus and configurations
|
|
US9619627B2
(en)
|
2011-09-25 |
2017-04-11 |
Theranos, Inc. |
Systems and methods for collecting and transmitting assay results
|
|
AP2014007588A0
(en)
|
2011-09-22 |
2014-04-30 |
Amgen Inc |
CD27L antigen binding proteins
|
|
US9810704B2
(en)
|
2013-02-18 |
2017-11-07 |
Theranos, Inc. |
Systems and methods for multi-analysis
|
|
US10012664B2
(en)
|
2011-09-25 |
2018-07-03 |
Theranos Ip Company, Llc |
Systems and methods for fluid and component handling
|
|
US9250229B2
(en)
|
2011-09-25 |
2016-02-02 |
Theranos, Inc. |
Systems and methods for multi-analysis
|
|
TWI679212B
(zh)
|
2011-11-15 |
2019-12-11 |
美商安進股份有限公司 |
針對bcma之e3以及cd3的結合分子
|
|
WO2013086443A1
(en)
|
2011-12-08 |
2013-06-13 |
Amgen Inc. |
Agonistic human lcat antigen binding proteins and their use in therapy
|
|
FR2984076A1
(fr)
|
2011-12-15 |
2013-06-21 |
Inst Rech Developpement Ird |
Surproduction de jasmonates dans des plantes transgeniques
|
|
CA2859364C
(en)
|
2011-12-16 |
2019-05-07 |
The Board Of Trustees Of The Leland Stanford Junior University |
Opsin polypeptides and methods of use thereof
|
|
AR091069A1
(es)
|
2012-05-18 |
2014-12-30 |
Amgen Inc |
Proteinas de union a antigeno dirigidas contra el receptor st2
|
|
WO2013184950A2
(en)
|
2012-06-06 |
2013-12-12 |
The United States Of America, As Represented By The Secretary, Department Of Health & Human Services |
Kits for detecting and monitoring endocrine disrupting chemicals (edcs)
|
|
CN104582717B
(zh)
|
2012-07-19 |
2018-03-13 |
雷德伍德生物科技股份有限公司 |
对cd22有特异性的抗体及其使用方法
|
|
EP2885010B1
(de)
|
2012-08-16 |
2020-01-01 |
Ipierian, Inc. |
Verfahren zur behandlung einer tauopathie
|
|
US9645151B2
(en)
|
2012-08-17 |
2017-05-09 |
California Institute Of Technology |
Targeting phosphofructokinase and its glycosylation form for cancer
|
|
US9816102B2
(en)
|
2012-09-13 |
2017-11-14 |
Indiana University Research And Technology Corporation |
Compositions and systems for conferring disease resistance in plants and methods of use thereof
|
|
WO2014066744A2
(en)
|
2012-10-25 |
2014-05-01 |
True North Therapeutics, Inc. |
Anti-complement c1s antibodies and uses thereof
|
|
ES2912396T3
(es)
|
2012-11-02 |
2022-05-25 |
Bioverativ Usa Inc |
Anticuerpos anti-C1s del complemento y uso de los mismos
|
|
TW201425336A
(zh)
|
2012-12-07 |
2014-07-01 |
Amgen Inc |
Bcma抗原結合蛋白質
|
|
TWI718086B
(zh)
|
2013-01-07 |
2021-02-11 |
英屬維爾京群島商遠東超級實驗室有限公司 |
通過干擾素的經皮和/或經粘膜給藥治療骨癌、皮膚癌、皮下癌、粘膜癌和/或粘膜下癌的方法和組合物
|
|
EP2948478B1
(de)
|
2013-01-25 |
2019-04-03 |
Amgen Inc. |
Antikörper gegen cdh19 für melanome
|
|
JO3519B1
(ar)
|
2013-01-25 |
2020-07-05 |
Amgen Inc |
تركيبات أجسام مضادة لأجل cdh19 و cd3
|
|
WO2014159764A1
(en)
|
2013-03-14 |
2014-10-02 |
Amgen Inc. |
Chrdl-1 antigen binding proteins and methods of treatment
|
|
US9850297B2
(en)
|
2013-03-15 |
2017-12-26 |
Amgen Inc. |
Secreted frizzle-related protein 5 (SFRP5) binding proteins
|
|
KR102215405B1
(ko)
|
2013-03-15 |
2021-02-10 |
암젠 인크 |
인간 pac1 항체
|
|
US9505849B2
(en)
|
2013-03-15 |
2016-11-29 |
Amgen Research (Munich) Gmbh |
Antibody constructs for influenza M2 and CD3
|
|
UY35484A
(es)
|
2013-03-15 |
2014-10-31 |
Amgen Res Munich Gmbh |
Molécula de unión de cadena simple que comprenden ABP de extremo N
|
|
HUE056580T2
(hu)
|
2013-05-30 |
2022-02-28 |
Kiniksa Pharmaceuticals Ltd |
Onkosztatin-M-receptor antigénjét kötõ fehérjék
|
|
SMT202000401T1
(it)
|
2013-06-10 |
2020-11-10 |
Ipierian Inc |
Metodi di trattamento di una taupatia
|
|
US9770461B2
(en)
|
2013-08-02 |
2017-09-26 |
California Institute Of Technology |
Tailored glycopolymers as anticoagulant heparin mimetics
|
|
US10227370B2
(en)
|
2013-08-02 |
2019-03-12 |
California Institute Of Technology |
Heparan sulfate/heparin mimetics with anti-chemokine and anti-inflammatory activity
|
|
TW201605896A
(zh)
|
2013-08-30 |
2016-02-16 |
安美基股份有限公司 |
Gitr抗原結合蛋白
|
|
US11545241B1
(en)
|
2013-09-07 |
2023-01-03 |
Labrador Diagnostics Llc |
Systems and methods for analyte testing and data management
|
|
AR097648A1
(es)
|
2013-09-13 |
2016-04-06 |
Amgen Inc |
Combinación de factores epigenéticos y compuestos biespecíficos que tienen como diana cd33 y cd3 en el tratamiento de leucemia mieloide
|
|
BR112016010454A2
(pt)
|
2013-11-27 |
2017-12-05 |
Ipierian Inc |
métodos para tratar uma taupatia
|
|
US9682123B2
(en)
|
2013-12-20 |
2017-06-20 |
The Trustees Of Columbia University In The City Of New York |
Methods of treating metabolic disease
|
|
ES2819865T3
(es)
*
|
2014-01-07 |
2021-04-19 |
Bioatla Llc |
Proteínas dirigidas a ortólogos
|
|
CA3177696A1
(en)
|
2014-02-20 |
2015-08-27 |
Allergan, Inc. |
Complement component c5 antibodies
|
|
AU2015223056B2
(en)
|
2014-02-27 |
2020-10-01 |
Allergan, Inc. |
Complement Factor Bb antibodies
|
|
WO2015196051A1
(en)
|
2014-06-19 |
2015-12-23 |
Regeneron Pharmaceuticals, Inc. |
Non-human animals having a humanized programmed cell death 1 gene
|
|
WO2016007886A1
(en)
|
2014-07-11 |
2016-01-14 |
Northwestern University |
Yeast-based biosensor
|
|
WO2016014621A1
(en)
*
|
2014-07-22 |
2016-01-28 |
The Regents Of The University Of California |
Endosomal escape domains for delivery of macromolecules into cells
|
|
ES2980787T3
(es)
|
2014-07-31 |
2024-10-03 |
Amgen Res Munich Gmbh |
Constructo de anticuerpo de cadena sencilla biespecífico con distribución tisular potenciada
|
|
AR101669A1
(es)
|
2014-07-31 |
2017-01-04 |
Amgen Res Munich Gmbh |
Constructos de anticuerpos para cdh19 y cd3
|
|
ES2743809T3
(es)
|
2014-07-31 |
2020-02-20 |
Amgen Res Munich Gmbh |
Constructos de anticuerpo monocatenarios biespecificos específicos de especies cruzadas optimizados
|
|
WO2016040767A2
(en)
|
2014-09-12 |
2016-03-17 |
Amgen Inc. |
Chrdl-1 epitopes and antibodies
|
|
WO2016090323A1
(en)
|
2014-12-05 |
2016-06-09 |
Prelude, Inc. |
Dcis recurrence and invasive breast cancer
|
|
BR112017010490A2
(pt)
|
2014-12-05 |
2018-04-03 |
Regeneron Pharma |
roedor, polipeptídeo cd47, célula ou tecido de roedor isolado, célula-tronco emprionária de roedor, embrião de roedor, e, métodos de produzir um roedor, de fornecimento de um roedor, de enxerto de células humanas em um roedor, de avaliação de eficácia terapêutica de uma droga direcionada a células humanas e de avaliar as propriedades farmacocinéticas, de avaliar a toxicidade específica e inespecífica de uma droga direcionada ao cd47 humano.
|
|
ES2841353T3
(es)
|
2014-12-09 |
2021-07-08 |
Regeneron Pharma |
Animales no humanos que tienen un gen del grupo de diferenciación 274 humanizado
|
|
WO2016130539A2
(en)
|
2015-02-09 |
2016-08-18 |
Memorial Sloan Kettering Cancer Center |
Multi-specific antibodies with affinity for human a33 antigen and dota metal complex and uses thereof
|
|
PL3283524T3
(pl)
|
2015-04-17 |
2023-06-12 |
Amgen Research (Munich) Gmbh |
Konstrukty biswoistego przeciwciała dla cdh3 i cd3
|
|
WO2016186948A1
(en)
|
2015-05-15 |
2016-11-24 |
Albert Einstein College Of Medicine, Inc. |
Gfp-derived fusion tags for protein expression
|
|
WO2016189118A1
(en)
|
2015-05-28 |
2016-12-01 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods of prognosis and treatment of patients suffering from acute myeloid leukemia
|
|
AU2016270587B2
(en)
|
2015-05-29 |
2020-12-24 |
Regeneron Pharmaceuticals, Inc. |
Non-human animals having a disruption in a C9ORF72 locus
|
|
TWI744242B
(zh)
|
2015-07-31 |
2021-11-01 |
德商安美基研究(慕尼黑)公司 |
Egfrviii及cd3抗體構築體
|
|
TWI717375B
(zh)
|
2015-07-31 |
2021-02-01 |
德商安美基研究(慕尼黑)公司 |
Cd70及cd3抗體構築體
|
|
TWI829617B
(zh)
|
2015-07-31 |
2024-01-21 |
德商安美基研究(慕尼黑)公司 |
Flt3及cd3抗體構築體
|
|
EA039859B1
(ru)
|
2015-07-31 |
2022-03-21 |
Эмджен Рисерч (Мюник) Гмбх |
Биспецифические конструкты антител, связывающие egfrviii и cd3
|
|
TWI793062B
(zh)
|
2015-07-31 |
2023-02-21 |
德商安美基研究(慕尼黑)公司 |
Dll3及cd3抗體構築體
|
|
TWI796283B
(zh)
|
2015-07-31 |
2023-03-21 |
德商安美基研究(慕尼黑)公司 |
Msln及cd3抗體構築體
|
|
RU2760582C2
(ru)
|
2015-09-02 |
2021-11-29 |
Иммутеп С.А.С. |
Анти-LAG-3 антитела
|
|
CN108366548B
(zh)
|
2015-11-20 |
2021-10-08 |
瑞泽恩制药公司 |
具有人源化淋巴细胞活化基因3的非人动物
|
|
CN117106085A
(zh)
|
2015-12-23 |
2023-11-24 |
美国安进公司 |
使用gipr结合蛋白与glp-1激动剂的组合来治疗或改善代谢病症的方法
|
|
US20190037816A1
(en)
|
2016-01-13 |
2019-02-07 |
Regeneron Pharmaceuticals, Inc. |
Rodents having an engineered heavy chain diversity region
|
|
JOP20170017B1
(ar)
|
2016-01-25 |
2021-08-17 |
Amgen Res Munich Gmbh |
تركيب صيدلي يتضمن تركيبات جسم مضاد ثنائي الاختصاص
|
|
AR107582A1
(es)
|
2016-02-03 |
2018-05-16 |
Amgen Res Munich Gmbh |
Constructos de anticuerpo biespecíficos para psma y cd3 que se ligan a células t
|
|
UA126657C2
(uk)
|
2016-02-03 |
2023-01-11 |
Емджен Рісерч (Мюнік) Ґмбг |
ОДНОЛАНЦЮГОВА КОНСТРУКЦІЯ АНТИТІЛА ДО BCMA І CD3<font face="Symbol">e</font>
|
|
WO2017136712A1
(en)
|
2016-02-04 |
2017-08-10 |
Regeneron Pharmaceuticals, Inc. |
Non-human animals having an engineered angptl8 gene
|
|
JP2019509059A
(ja)
|
2016-02-16 |
2019-04-04 |
リジェネロン・ファーマシューティカルズ・インコーポレイテッドRegeneron Pharmaceuticals, Inc. |
変異型キヌレニナーゼ遺伝子を有する非ヒト動物
|
|
JOP20170091B1
(ar)
|
2016-04-19 |
2021-08-17 |
Amgen Res Munich Gmbh |
إعطاء تركيبة ثنائية النوعية ترتبط بـ cd33 وcd3 للاستخدام في طريقة لعلاج اللوكيميا النخاعية
|
|
MX381216B
(es)
|
2016-09-30 |
2025-03-12 |
Regeneron Pharma |
Animales no humanos que tienen una expansion de repeticiones de hexanucleotidos en un locus c9orf72.
|
|
US11280790B2
(en)
*
|
2016-10-04 |
2022-03-22 |
Svar Life Science Ab |
System and products for improved quantification of ADCC activity
|
|
EP4567119A3
(de)
|
2016-11-04 |
2025-09-24 |
Regeneron Pharmaceuticals, Inc. |
Nichtmenschliche tiere mit manipuliertem immunglobulin-lambda-leichtketten-locus
|
|
US10174122B2
(en)
|
2017-01-06 |
2019-01-08 |
Eutilex Co., Ltd. |
Anti-human 4-1BB antibodies and uses thereof
|
|
EP4480537A3
(de)
|
2017-01-17 |
2025-03-12 |
Amgen Inc. |
Verfahren zur behandlung oder linderung von stoffwechselerkrankungen mit glp-1-rezeptoragonisten, die mit antagonisten für den magenhemmenden peptidrezeptor (gipr) konjugiert sind
|
|
CR20190408A
(es)
|
2017-02-02 |
2020-01-31 |
Amgen Inc |
Composición farmacéutica de bajo ph que comprende construcciones de anticuerpos que activan linfocitos t antecedentes
|
|
WO2018148223A1
(en)
|
2017-02-09 |
2018-08-16 |
Memorial Sloan Kettering Cancer Center |
Anti-kir3dl1 antibodies
|
|
EP3882271A3
(de)
|
2017-02-10 |
2022-01-05 |
Eutilex Co., Ltd. |
Ifn-gamma-induzierbarer regulatorischer t-zell-umwandelbarer anti-krebs-antikörper (irtca) und verwendungen davon
|
|
PT3583125T
(pt)
|
2017-02-16 |
2025-04-04 |
Sonnet Biotherapeutics Inc |
Proteínas de fusão ao domínio de ligação à albumina
|
|
SG11201907490XA
(en)
|
2017-02-27 |
2019-09-27 |
Regeneron Pharma |
Non-human animal models of retinoschisis
|
|
MA48763A
(fr)
|
2017-05-05 |
2020-04-08 |
Amgen Inc |
Composition pharmaceutique comprenant des constructions d'anticorps bispécifiques pour un stockage et une administration améliorés
|
|
CA3062439A1
(en)
|
2017-05-05 |
2018-11-08 |
Memorial Sloan Kettering Cancer Center |
Modular self assembly disassembly (sada) technologies
|
|
JOP20190259A1
(ar)
|
2017-05-31 |
2019-10-31 |
Amgen Inc |
بروتينات ربط مولد ضد مضادة لـ jagged1
|
|
UY37753A
(es)
|
2017-06-02 |
2018-11-30 |
Amgen Inc |
Antagonistas de péptido pac1
|
|
CA3062194A1
(en)
|
2017-06-20 |
2018-12-27 |
Amgen Inc. |
Method of treating or ameliorating metabolic disorders using binding proteins for gastric inhibitory peptide receptor (gipr) in combination with glp-1 agonists
|
|
JP7250706B2
(ja)
|
2017-06-21 |
2023-04-03 |
アムジエン・インコーポレーテツド |
胃抑制ペプチド受容体(gipr)に対するアンタゴニスト結合タンパク質/glp-1受容体アゴニスト融合タンパク質を使用した代謝障害の治療又は寛解方法
|
|
MA68842B1
(fr)
|
2017-08-04 |
2025-01-31 |
Amgen Inc. |
Procédé de conjugaison de cys-mabs
|
|
CA3109871A1
(en)
|
2017-08-22 |
2019-02-28 |
Monash University |
Screening assays, modulators and modulation of activation of receptor for advanced glycation end-products (rage)
|
|
WO2019113065A1
(en)
|
2017-12-05 |
2019-06-13 |
Regeneron Pharmaceuticals, Inc. |
Non-human animals having an engineered immunoglobulin lambda light chain and uses thereof
|
|
AU2018383679C1
(en)
|
2017-12-11 |
2026-05-28 |
Amgen Inc. |
Continuous manufacturing process for bispecific antibody products
|
|
TW201940518A
(zh)
|
2017-12-29 |
2019-10-16 |
美商安進公司 |
針對muc17和cd3之雙特異性抗體構建體
|
|
BR112020016306A2
(pt)
|
2018-02-12 |
2020-12-15 |
Curators Of The University Of Missouri |
Gene (saur) suprarregulado pequeno de auxina para o melhoramento da arquitetura do sistema radicular da planta, tolerância ao encharcamento, resistência à seca, e rendimento
|
|
EP3765516A2
(de)
*
|
2018-03-14 |
2021-01-20 |
Elstar Therapeutics, Inc. |
Multifunktionale moleküle und verwendungen davon
|
|
IL318469A
(en)
|
2018-06-14 |
2025-03-01 |
Regeneron Pharma |
Non-human animals capable of reorganizing transgenic DH-DH, and their uses
|
|
WO2020025532A1
(en)
|
2018-07-30 |
2020-02-06 |
Amgen Research (Munich) Gmbh |
Prolonged administration of a bispecific antibody construct binding to cd33 and cd3
|
|
BR112021002032A2
(pt)
|
2018-08-03 |
2021-07-20 |
Amgen Research (Munich) Gmbh |
construtos de anticorpos para cldn18.2 e cd3
|
|
WO2020056338A1
(en)
|
2018-09-14 |
2020-03-19 |
Prelude Corporation |
Method of selection for treatment of subjects at risk of invasive breast cancer
|
|
BR112021005669A2
(pt)
|
2018-09-28 |
2021-06-22 |
Amgen Inc. |
anticorpos contra bcma solúvel
|
|
MX2021003976A
(es)
|
2018-10-11 |
2021-05-27 |
Amgen Inc |
Procesamiento posterior de constructos de anticuerpos biespecificos.
|
|
US20220025058A1
(en)
|
2018-11-06 |
2022-01-27 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and pharmaceutical compositions for the treatment of acute myeloid leukemia by eradicating leukemic stem cells
|
|
WO2020131632A1
(en)
|
2018-12-20 |
2020-06-25 |
Regeneron Pharmaceuticals, Inc. |
Nuclease-mediated repeat expansion
|
|
CN120005022A
(zh)
|
2019-01-03 |
2025-05-16 |
因外泰克斯公司 |
用于增加治疗剂在犬中的半衰期的组合物及使用方法
|
|
US12582726B1
(en)
|
2019-04-05 |
2026-03-24 |
Earli Inc. |
Synthetic cancer-specific promoters
|
|
EP3946470A4
(de)
|
2019-04-05 |
2023-05-31 |
Earli Inc. |
Verbesserte verfahren und zusammensetzungen für synthetische biomarker
|
|
PT3979790T
(pt)
|
2019-06-05 |
2026-05-05 |
Regeneron Pharma |
Roedores possuindo um reportrio limitado de cadeias leves lambda expressadas a partir do lcus kappa e suas utilizaes
|
|
US20220259547A1
(en)
|
2019-06-13 |
2022-08-18 |
Amgeng Inc. |
Automated biomass-based perfusion control in the manufacturing of biologics
|
|
BR102019017792A2
(pt)
|
2019-08-27 |
2021-11-16 |
Fundação Oswaldo Cruz |
Receptáculo proteico, método para produção do receptáculo, método de identificação de patógenos ou de diagnóstico de doenças, e, uso do receptáculo
|
|
US20220306741A1
(en)
|
2019-09-10 |
2022-09-29 |
Amgen Inc. |
Purification Method for Bispecific antigen-binding Polypeptides with Enhanced Protein L Capture Dynamic Binding Capacity
|
|
WO2021097344A1
(en)
|
2019-11-13 |
2021-05-20 |
Amgen Inc. |
Method for reduced aggregate formation in downstream processing of bispecific antigen-binding molecules
|
|
US20230093169A1
(en)
|
2020-01-22 |
2023-03-23 |
Amgen Research (Munch) Gmbh |
Combinations of antibody constructs and inhibitors of cytokine release syndrome and uses thereof
|
|
CN115427454A
(zh)
|
2020-03-19 |
2022-12-02 |
安进公司 |
针对粘蛋白17的抗体及其用途
|
|
JP7832123B2
(ja)
|
2020-05-11 |
2026-03-17 |
インベテックス インコーポレイテッド |
治療薬のイヌにおける半減期を増加させるための組成物及びその使用方法
|
|
WO2021236638A1
(en)
|
2020-05-19 |
2021-11-25 |
Amgen Inc. |
Mageb2 binding constructs
|
|
JP2023527972A
(ja)
|
2020-05-29 |
2023-07-03 |
アムジエン・インコーポレーテツド |
Cd33及びcd3に結合する二重特異性コンストラクトの有害作用軽減投与
|
|
WO2022008488A1
(en)
|
2020-07-06 |
2022-01-13 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Use of slamf1 as a biomarker in colorectal cancer
|
|
CN116096741B
(zh)
|
2020-07-10 |
2024-10-18 |
因外泰克斯公司 |
用于延长治疗剂在猫科动物中的半衰期的组合物和使用方法
|
|
WO2022013256A1
(en)
|
2020-07-15 |
2022-01-20 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Use of cd160 as a biomarker in acute myeloid leukemia
|
|
US20230375558A1
(en)
|
2020-09-22 |
2023-11-23 |
3Helix, Inc. |
Methods for Using Collagen Hybridizing Peptides to Determine Collagen Content
|
|
AU2021373318A1
(en)
|
2020-11-06 |
2023-05-25 |
Amgen Inc. |
Antigen binding domain with reduced clipping rate
|
|
CA3200317A1
(en)
|
2020-11-06 |
2022-05-12 |
Amgen Inc. |
Multitargeting bispecific antigen-binding molecules of increased selectivity
|
|
EP4240770A1
(de)
|
2020-11-06 |
2023-09-13 |
Amgen Research (Munich) GmbH |
Polypeptidkonstrukte mit selektiver bindung an cldn6 und cd3
|
|
TW202225188A
(zh)
|
2020-11-06 |
2022-07-01 |
德商安美基研究(慕尼黑)公司 |
與cd3結合的多肽構建體
|
|
EP4255933A4
(de)
|
2020-12-07 |
2025-07-23 |
Invetx Inc |
Zusammensetzungen zur erhöhung der halbwertszeit eines therapeutischen mittels bei nutztieren und verfahren zur verwendung
|
|
CA3203106A1
(en)
|
2021-01-20 |
2022-07-28 |
Parag Mallick |
Systems and methods for biomolecule quantitation
|
|
US20250282887A1
(en)
|
2021-04-02 |
2025-09-11 |
Amgen Inc. |
Mageb2 binding constructs
|
|
US20220331241A1
(en)
|
2021-04-16 |
2022-10-20 |
Regeneron Pharmaceuticals, Inc. |
Treatment of x-linked juvenile retinoschisis
|
|
MX2023012931A
(es)
|
2021-05-06 |
2023-11-13 |
Amgen Res Munich Gmbh |
Moleculas de union a antigeno dirigidas a cd20 y cd22 para su uso en enfermedades proliferativas.
|
|
JP2024535618A
(ja)
|
2021-10-14 |
2024-09-30 |
アシモフ,インコーポレーテッド |
インテグラーゼ、ランディングパッド構造、およびそれを含む操作された細胞
|
|
IL312487A
(en)
|
2021-11-09 |
2024-07-01 |
Asimov Inc |
Stable production systems for adeno-associated virus vector production
|
|
AU2023268600A1
(en)
|
2022-05-12 |
2024-11-07 |
Amgen Research (Munich) Gmbh |
Multichain multitargeting bispecific antigen-binding molecules of increased selectivity
|
|
US20240102045A1
(en)
|
2022-07-19 |
2024-03-28 |
Regeneron Pharmaceuticals, Inc. |
Vectors, genetically modified cells, and genetically modified non-human animals comprising the same
|
|
AU2023343470A1
(en)
|
2022-09-14 |
2025-02-06 |
Amgen Inc. |
Bispecific molecule stabilizing composition
|
|
WO2024104551A1
(en)
|
2022-11-14 |
2024-05-23 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Use of the population of slamf4+ ccr5+ effector memory cd4+ t cells as a biomarker in rheumatoid arthritis
|
|
KR20250137204A
(ko)
|
2022-12-27 |
2025-09-17 |
인베티엑스 인코포레이티드 |
신생아 fc 수용체(fcrn)에 대한 결합이 변경된 폴리펩타이드 및 사용 방법
|
|
AU2023415535A1
(en)
|
2022-12-27 |
2025-07-10 |
Invetx, Inc. |
Polypeptides with altered binding to neonatal fc receptor (fcrn) and methods of use
|
|
CN121002059A
(zh)
|
2023-01-20 |
2025-11-21 |
因外泰克斯公司 |
用于伴侣动物的双特异性结合剂
|
|
MX2025014635A
(es)
|
2023-06-14 |
2026-02-03 |
Amgen Inc |
Moleculas captadoras de enmascaramiento de celulas t
|
|
WO2025019535A1
(en)
*
|
2023-07-20 |
2025-01-23 |
The Johns Hopkins University |
Methods and related aspects of biosensors
|
|
WO2025171307A1
(en)
|
2024-02-08 |
2025-08-14 |
Regeneron Pharmaceuticals, Inc. |
Vectors, genetically modified cells, and genetically modified non-human animals comprising the same
|
|
WO2025181096A1
(en)
|
2024-02-26 |
2025-09-04 |
Institut National de la Santé et de la Recherche Médicale |
Use of vdac and lamp1 as markers for detecting pocked red blood cells
|
|
US20260123608A1
(en)
|
2024-08-06 |
2026-05-07 |
Regeneron Pharmaceuticals, Inc. |
Non-human animals having modified immunoglobulin heavy chain constant region locus and uses thereof
|
|
WO2026096736A1
(en)
|
2024-10-31 |
2026-05-07 |
Regeneron Pharmaceuticals, Inc. |
Rodents expressing humanized polymeric immunoglobulin receptor
|
|
WO2026136785A1
(en)
|
2024-12-19 |
2026-06-25 |
Amgen Inc. |
T cell engager masking molecules with reduced isomerization tendencies
|