ATE295540T1 - Perfektionierte magnetische teilchen, verfahren zu ihrer herstellung und ihrer anwendungen zum trennen von molekülen - Google Patents

Perfektionierte magnetische teilchen, verfahren zu ihrer herstellung und ihrer anwendungen zum trennen von molekülen

Info

Publication number
ATE295540T1
ATE295540T1 AT99900498T AT99900498T ATE295540T1 AT E295540 T1 ATE295540 T1 AT E295540T1 AT 99900498 T AT99900498 T AT 99900498T AT 99900498 T AT99900498 T AT 99900498T AT E295540 T1 ATE295540 T1 AT E295540T1
Authority
AT
Austria
Prior art keywords
particles
applications
production
magnetic particles
heat
Prior art date
Application number
AT99900498T
Other languages
English (en)
Inventor
Abdelhamid Elaissari
Christian Pichot
Bernard Mandrand
Original Assignee
Bio Merieux
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bio Merieux filed Critical Bio Merieux
Application granted granted Critical
Publication of ATE295540T1 publication Critical patent/ATE295540T1/de

Links

Classifications

    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01F—MAGNETS; INDUCTANCES; TRANSFORMERS; SELECTION OF MATERIALS FOR THEIR MAGNETIC PROPERTIES
    • H01F1/00—Magnets or magnetic bodies characterised by the magnetic materials therefor; Selection of materials for their magnetic properties
    • H01F1/01—Magnets or magnetic bodies characterised by the magnetic materials therefor; Selection of materials for their magnetic properties of inorganic materials
    • H01F1/03—Magnets or magnetic bodies characterised by the magnetic materials therefor; Selection of materials for their magnetic properties of inorganic materials characterised by their coercivity
    • H01F1/032—Magnets or magnetic bodies characterised by the magnetic materials therefor; Selection of materials for their magnetic properties of inorganic materials characterised by their coercivity of hard-magnetic materials
    • H01F1/10—Magnets or magnetic bodies characterised by the magnetic materials therefor; Selection of materials for their magnetic properties of inorganic materials characterised by their coercivity of hard-magnetic materials non-metallic substances, e.g. ferrites, e.g. [(Ba,Sr)O(Fe2O3)6] ferrites with hexagonal structure
    • H01F1/11—Magnets or magnetic bodies characterised by the magnetic materials therefor; Selection of materials for their magnetic properties of inorganic materials characterised by their coercivity of hard-magnetic materials non-metallic substances, e.g. ferrites, e.g. [(Ba,Sr)O(Fe2O3)6] ferrites with hexagonal structure in the form of particles
    • H01F1/111—Magnets or magnetic bodies characterised by the magnetic materials therefor; Selection of materials for their magnetic properties of inorganic materials characterised by their coercivity of hard-magnetic materials non-metallic substances, e.g. ferrites, e.g. [(Ba,Sr)O(Fe2O3)6] ferrites with hexagonal structure in the form of particles with a non-magnetic core
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C1/00—Magnetic separation
    • B03C1/005—Pretreatment specially adapted for magnetic separation
    • B03C1/01—Pretreatment specially adapted for magnetic separation by addition of magnetic adjuvants
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G01N33/54326—Magnetic particles
    • G01N33/5434—Magnetic particles using magnetic particle immunoreagent carriers which constitute new materials per se
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2446/00—Magnetic particle immunoreagent carriers
    • G01N2446/20—Magnetic particle immunoreagent carriers the magnetic material being present in the particle core
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2446/00—Magnetic particle immunoreagent carriers
    • G01N2446/80—Magnetic particle immunoreagent carriers characterised by the agent used to coat the magnetic particles, e.g. lipids
    • G01N2446/86—Magnetic particle immunoreagent carriers characterised by the agent used to coat the magnetic particles, e.g. lipids the coating being pre-functionalised for attaching immunoreagents, e.g. aminodextran
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S428/00—Stock material or miscellaneous articles
    • Y10S428/90—Magnetic feature
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
    • Y10T428/2991—Coated
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
    • Y10T428/2991—Coated
    • Y10T428/2998—Coated including synthetic resin or polymer

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • Power Engineering (AREA)
  • Peptides Or Proteins (AREA)
  • Soft Magnetic Materials (AREA)
  • Hard Magnetic Materials (AREA)
  • Compounds Of Iron (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
AT99900498T 1998-01-06 1999-01-06 Perfektionierte magnetische teilchen, verfahren zu ihrer herstellung und ihrer anwendungen zum trennen von molekülen ATE295540T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9800220A FR2773416B1 (fr) 1998-01-06 1998-01-06 Particules magnetiques perfectionnees, leurs procedes d'obtention et leurs utilisations dans la separation de molecules
PCT/FR1999/000011 WO1999035500A1 (fr) 1998-01-06 1999-01-06 Particules magnetiques perfectionnees, leurs procedes d'obtention et leurs utilisations dans la separation de molecules

Publications (1)

Publication Number Publication Date
ATE295540T1 true ATE295540T1 (de) 2005-05-15

Family

ID=9521678

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99900498T ATE295540T1 (de) 1998-01-06 1999-01-06 Perfektionierte magnetische teilchen, verfahren zu ihrer herstellung und ihrer anwendungen zum trennen von molekülen

Country Status (10)

Country Link
US (1) US6521341B1 (de)
EP (1) EP1046037B1 (de)
JP (1) JP4443762B2 (de)
AT (1) ATE295540T1 (de)
AU (1) AU1973499A (de)
CA (1) CA2316824A1 (de)
DE (1) DE69925241T2 (de)
ES (1) ES2242374T3 (de)
FR (1) FR2773416B1 (de)
WO (1) WO1999035500A1 (de)

Families Citing this family (49)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2800635B1 (fr) 1999-11-05 2002-07-26 Bio Merieux Nanospheres composites, conjugues derives, procede de preparation et leurs utilisations
EP1108743B1 (de) * 1999-12-08 2006-11-15 JSR Corporation Trennung von Viren und Nachweis von Viren
FR2804117B1 (fr) * 2000-01-21 2004-08-20 Bio Merieux Procede d'isolement de proteines et/ou d'acides nucleiques, complexes de particules et de proteines et/ou d'acides nucleiques, reactif et applications
WO2002016571A1 (en) * 2000-08-21 2002-02-28 National Institute Of Advanced Industrial Science And Technology Magnetic particles having lower limit critical solution temperature
US7338805B2 (en) 2001-05-04 2008-03-04 Bio Merieux Labeling reagents, methods for synthesizing such reagents and methods for detecting biological molecules
FR2824563B1 (fr) * 2001-05-10 2004-12-03 Bio Merieux Particules composites, conjugues derives, procede de preparation et applications
FR2826592B1 (fr) 2001-06-27 2003-08-15 Bio Merieux Procede, dispositif, et equipement de separation par voie humide de micro particules magnetiques
FR2829580B1 (fr) 2001-09-07 2004-02-13 Bio Merieux Procede de lecture, de detection ou de quantification, hybrides ou complexes utilises dans ce procede et biopuce mettant en oeuvre ledit procede
JP4072994B2 (ja) * 2001-10-11 2008-04-09 学校法人日本大学 磁性粒子
US7282540B2 (en) * 2002-03-25 2007-10-16 Jsr Corporation Process for producing particles for diagnostic reagent
US20050079132A1 (en) * 2003-04-08 2005-04-14 Xingwu Wang Medical device with low magnetic susceptibility
US20050025797A1 (en) * 2003-04-08 2005-02-03 Xingwu Wang Medical device with low magnetic susceptibility
WO2004097417A1 (en) * 2003-05-02 2004-11-11 Canon Kabushiki Kaisha Structured construct and producing method therefor
FR2855832B1 (fr) 2003-06-03 2007-09-14 Biomerieux Sa Procede de diagnostic et/ou de pronostic d'un syndrome septique
FR2857375B1 (fr) * 2003-07-10 2007-11-09 Biomerieux Sa Procede de detection et/ou d'identification de bacteries de genre staphylococcus
US20050112625A1 (en) * 2003-08-22 2005-05-26 Konica Minolta Medical & Graphic, Inc. DNA amplification method
FR2868071B1 (fr) 2004-03-26 2006-06-09 Biomerieux Sa Reactifs de marquage, procedes de synthese de tels reactifs et procedes de detection de molecules biologiques
FR2868433B1 (fr) 2004-04-06 2008-01-18 Biomerieux Sa Procede pour le pronostic et/ou le diagnostic d'un cancer
FR2881437B1 (fr) 2005-01-31 2010-11-19 Biomerieux Sa Procede pour le diagnostic/pronostic d'un syndrome septique
JP4811565B2 (ja) * 2005-03-31 2011-11-09 Ｊｓｒ株式会社 多孔質表面を有する磁性粒子およびその製造方法、生化学用担体、ならびにビオチン類結合用粒子
US7989065B2 (en) * 2005-05-20 2011-08-02 Seradyn, Inc. Magnetically-responsive microparticles with improved response times
FR2886735B1 (fr) 2005-06-01 2015-09-11 Biomerieux Sa Procede de marquage ou de traitement d'un echantillon biologique contenant des molecules biologiques d'interet, notamment des acides nucleiques
FR2902430B1 (fr) 2005-11-25 2012-11-02 Biomerieux Sa Oligonucleotides, utilisation, methode de detection et kit permettant de diagnostiquer la presence des genes h5 et n1 du virus d'influenza a
FR2894970B1 (fr) * 2005-12-15 2008-01-25 Biomerieux Sa Procede de preparation de particules composites, particules composites obtenues et leur utilisation dans un test diagnostic
FR2900158A1 (fr) 2006-04-25 2007-10-26 Biomerieux Sa Nouvelle sonde de detection agissant par reconnaissance moleculaire
FR2902799B1 (fr) * 2006-06-27 2012-10-26 Millipore Corp Procede et unite de preparation d'un echantillon pour l'analyse microbiologique d'un liquide
FR2906537A1 (fr) 2006-09-28 2008-04-04 Biomerieux Sa Procede de diagnostic in vitro du cancer broncho-pulmonaire par detection des transcrits majoritaires alternatifs du gene klk8 codant la kallicreine 8 et son utilisation pour le pronostic de survie
US8362217B2 (en) 2006-12-21 2013-01-29 Emd Millipore Corporation Purification of proteins
US8569464B2 (en) * 2006-12-21 2013-10-29 Emd Millipore Corporation Purification of proteins
US8163886B2 (en) * 2006-12-21 2012-04-24 Emd Millipore Corporation Purification of proteins
US7981688B2 (en) 2007-03-08 2011-07-19 University Of Washington Stimuli-responsive magnetic nanoparticles and related methods
DE102007020220B3 (de) * 2007-04-28 2008-11-13 Forschungszentrum Karlsruhe Gmbh Verfahren zur magnetisch unterstützten Extraktion
FR2917095B1 (fr) 2007-06-07 2009-07-17 Biomerieux Sa Dispositif de lyse de microorganismes presents dans un echantillon environnemental ou clinique et d'extraction des acides nucleiques desdits microorganismes aux fins d'analyse.
FR2917090B1 (fr) * 2007-06-11 2012-06-15 Biomerieux Sa Reactifs de marquage portant des fonctions diazo et nitro, procedes de synthese de tels reactifs et procedes de detection de molecules biologiques
FR2921064A1 (fr) * 2007-09-14 2009-03-20 Biomerieux Sa Oligonucleotides, utilisation, methode de detection et kit permettant de diagnostiquer la presence du gene e1 du virus du chikungunya
WO2009151514A1 (en) * 2008-06-11 2009-12-17 Millipore Corporation Stirred tank bioreactor
US20100018674A1 (en) * 2008-07-22 2010-01-28 Donald John Enzinna Reservoir with moveable partition for quick recovery
FR2934595B1 (fr) 2008-07-29 2013-04-05 Biomerieux Sa Reactifs de marquage ayant un noyau pyridine portant une fonction diazomethyle, procedes de synthese de tels reactifs et procedes de detection de molecules biologiques
FR2939445B1 (fr) 2008-12-10 2013-05-03 Biomerieux Sa Systeme automatise de lyse de microorganismes presents dans un echantillon, d'extraction et de purification des acides nucleiques desdits microorganismes aux fins d'analyse.
CN102257122B (zh) * 2008-12-16 2015-07-29 Emd密理博公司 搅拌槽反应器及方法
JP5832903B2 (ja) 2009-01-19 2015-12-16 ビオメリューＢｉｏｍｅｒｉｅｕｘ 院内感染罹患の患者の易罹患性を判定し、敗血症症候群の進行の予後を確立する方法
US8426214B2 (en) * 2009-06-12 2013-04-23 University Of Washington System and method for magnetically concentrating and detecting biomarkers
US9080933B2 (en) 2009-11-09 2015-07-14 University Of Washington Through Its Center For Commercialization Stimuli-responsive polymer diagnostic assay comprising magnetic nanoparticles and capture conjugates
US20110117668A1 (en) * 2009-11-09 2011-05-19 University Of Washington Through Its Center For Commercialization Self-powered smart diagnostic devices
DK2571903T3 (da) 2010-05-17 2019-11-04 Emd Millipore Corp Polymerer, der reagerer på stimuli, til oprensning af biomolekyler
WO2011150976A1 (en) 2010-06-04 2011-12-08 bioMérieux Method and kit for the prognosis of colorectal cancer
US9110079B2 (en) 2010-09-29 2015-08-18 Biomerieux Method and kit for establishing an in vitro prognosis on a patient exhibiting SIRS
WO2012129758A1 (en) 2011-03-25 2012-10-04 Biomerieux Method and kit for determining in vitro probability for individual to suffer from colorectal cancer
CN104987474B (zh) * 2015-07-13 2017-07-28 中国科学院新疆理化技术研究所 一种降低油田污水矿化度的磁性除盐剂的制备方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NO155316C (no) 1982-04-23 1987-03-11 Sintef Fremgangsmaate for fremstilling av magnetiske polymerpartikler.
ATE102256T1 (de) 1988-11-21 1994-03-15 Dynal As Sonden aus nukleinsaeuren.
FR2645160B1 (de) * 1989-03-31 1992-10-02 Rhone Poulenc Chimie
DE585868T1 (de) 1992-08-31 1994-09-22 Fujirebio Kk Magnetisches Teilchen und seine Verwendung in einem Immunotest.
CA2146964C (en) * 1992-10-15 2005-11-29 Olavi Siiman Particles having gelatin-aminodextran coatings of and processes for making same
DE69428445T2 (de) * 1993-07-08 2002-05-29 Fujirebio Inc., Tokio/Tokyo Magnetische mit gelatine überzogene teilchen und sie verwendender immunoassay
GB9402334D0 (en) * 1994-02-07 1994-03-30 Bradtecltd Magnetic particles a method for the preparation thereof and their use in the purification of solutions
FR2749082B1 (fr) * 1996-05-24 1998-06-26 Bio Merieux Particules superparamagnetiques et monodispersees

Also Published As

Publication number Publication date
EP1046037B1 (de) 2005-05-11
EP1046037A1 (de) 2000-10-25
FR2773416A1 (fr) 1999-07-09
CA2316824A1 (fr) 1999-07-15
JP4443762B2 (ja) 2010-03-31
DE69925241D1 (de) 2005-06-16
ES2242374T3 (es) 2005-11-01
US6521341B1 (en) 2003-02-18
DE69925241T2 (de) 2006-01-26
JP2002501175A (ja) 2002-01-15
FR2773416B1 (fr) 2000-02-11
WO1999035500A1 (fr) 1999-07-15
AU1973499A (en) 1999-07-26

Similar Documents

Publication Publication Date Title
ATE295540T1 (de) Perfektionierte magnetische teilchen, verfahren zu ihrer herstellung und ihrer anwendungen zum trennen von molekülen
DE602004026324D1 (de) Netkügelchen
CA2262018A1 (en) Nanoparticles having oligonucleotides attached thereto and uses therefor
WO2003089906A3 (en) Functionalized nanoparticles and methods of use
WO2002018643A3 (en) Nanoparticles having oligonucleotides attached thereto and uses therefor
CA2349948A1 (en) A chromatography method and a column material useful in said method
DE69840704D1 (de) Nukleinsäuremoleküle, welche für proteine kodieren, die fructosyltransferase-aktivität aufweisen und verfahren zur herstellung von langkettigem inulin
ATE440966T1 (de) Mobilitätsmodifizierte nukleobasenpolymere und verfahren zu deren verwendung
ATE333943T1 (de) Trennungsverfahren von substanzen durch dielektrophoresis
AU6380001A (en) Porous ferro- or ferrimagnetic glass particles for isolating molecules
ATE280225T1 (de) Simultane isolierung und quantifizierung von dna
WO1999047536A3 (de) Verfahren zur synthese von nucleinsäuremolekülen
ATE238411T1 (de) Verfahren zur lyse von mikroorganismen
DE69604399D1 (de) Verfahren und vorrichtung zur herstellung von ringförmigen werkstücken aus verbundmaterial und vorformlinge für diese werkstücke
DE69902600D1 (de) Styrolharzzusammensetzung und Verfahren zu ihrer Herstellung, sowie Verfahren zur Herstellung von Formkörpern aus Styrolharz
DE50115287D1 (de) Verfahren zur abtrennung von komponenten aus flüssigen und gasförmigen medien mit nanokompositen
ID29110A (id) Komposisi dan proses untuk pemindahan gas-gas asam
DE69938462D1 (de) Zähigkeitsvermittler aus emulsionspolymerisiertem silikonkautschuk, verfahren zu seiner herstellung und diesen enthaltende verbundwerkstoffe
Cao et al. Hydroxyethylcellulose‐graft‐poly (2‐(dimethylamino) ethyl methacrylate) as physically adsorbed coating for protein separation by CE
DE69728113D1 (de) Negativer widerstand des molekulardispersionstyps und verfahren zur herstellung
DE60321449D1 (de) Verfahren zur zweidimensionalen konformationsabhängigen trennung nichtzirkulärer nukleinsäuren
EP0981535A4 (de) Verfahren zur herstellung und reinigung von nukleinsäuremolekülen
DE69924120D1 (de) Für ataxin-2-bindende proteine kodierende nukleinsäure, damit verwandten produkten und verfahren zur deren anwendung
Huang et al. Preparative separation of enantiomers based on functional nucleic acids modified gold nanoparticles
NO20012630D0 (no) Fremgangsmåte for separering av nukleinsyrer i populasjoner

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties