ATE295876T1 - Dedifferenzierte, programmierbare stammzellen monozytären ursprungs, sowie deren herstellung und verwendung - Google Patents
Dedifferenzierte, programmierbare stammzellen monozytären ursprungs, sowie deren herstellung und verwendungInfo
- Publication number
- ATE295876T1 ATE295876T1 AT03727271T AT03727271T ATE295876T1 AT E295876 T1 ATE295876 T1 AT E295876T1 AT 03727271 T AT03727271 T AT 03727271T AT 03727271 T AT03727271 T AT 03727271T AT E295876 T1 ATE295876 T1 AT E295876T1
- Authority
- AT
- Austria
- Prior art keywords
- stem cells
- production
- differentiated
- programmable stem
- monocytic origin
- Prior art date
Links
- 210000000130 stem cell Anatomy 0.000 title abstract 4
- 238000004519 manufacturing process Methods 0.000 title abstract 3
- 210000001616 monocyte Anatomy 0.000 abstract 2
- 108010002386 Interleukin-3 Proteins 0.000 abstract 1
- 108010046938 Macrophage Colony-Stimulating Factor Proteins 0.000 abstract 1
- 102000007651 Macrophage Colony-Stimulating Factor Human genes 0.000 abstract 1
- 210000004027 cell Anatomy 0.000 abstract 1
- 239000001963 growth medium Substances 0.000 abstract 1
- 239000000825 pharmaceutical preparation Substances 0.000 abstract 1
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| DE10214095A DE10214095C1 (de) | 2002-03-28 | 2002-03-28 | Dedifferenzierte, programmierbare Stammzellen monozytären Ursprungs, sowie deren Herstellung und Verwendung |
| US10/372,657 US20040101962A1 (en) | 2002-03-28 | 2003-02-25 | Dedifferentiated, programmable stem cells of monocytic origin, and their production and use |
| PCT/EP2003/002121 WO2003083091A1 (de) | 2002-03-28 | 2003-02-25 | Dedifferenzierte, programmierbare stammzellen monozytären ursprungs, sowie deren herstellung und verwendung |
| PCT/EP2003/003279 WO2003083092A1 (en) | 2002-03-28 | 2003-03-28 | Dedifferentiated, programmable stem cells of monocytic origin, and their production and use |
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| GB9502022D0 (en) * | 1995-02-02 | 1995-03-22 | Abuljadayel Ilham M S | A method for preparing lymphohaematopoietic progenitor cells |
| TWI288779B (en) * | 2002-03-28 | 2007-10-21 | Blasticon Biotech Forschung | Dedifferentiated, programmable stem cells of monocytic origin, and their production and use |
| DE10231655A1 (de) * | 2002-07-12 | 2004-02-26 | Blasticon Biotechnologische Forschung Gmbh | Transplantat-Akzeptanz induzierende Zellen monozytären Ursprungs, sowie deren Herstellung und Verwendung |
| EP2357223A3 (de) * | 2002-11-07 | 2012-11-07 | University Of Chicago | Humane Stammzellen und Verfahren zur Verwendung |
| US20040136973A1 (en) * | 2002-11-07 | 2004-07-15 | Eliezer Huberman | Human stem cell materials and methods |
| ATE408670T1 (de) * | 2003-07-11 | 2008-10-15 | Blasticon Biotech Forschung | Autologous selbst-toleranz induzierende zellen monozytären ursprungs und ihren verwendung in artzneimitteln |
| ITRM20030376A1 (it) | 2003-07-31 | 2005-02-01 | Univ Roma | Procedimento per l'isolamento e l'espansione di cellule staminali cardiache da biopsia. |
| WO2005071065A1 (en) * | 2004-01-26 | 2005-08-04 | Cognis France S.A.S | Method for studying functional interactions between sensory neurons and keratinocytes or melanocytes |
| EP1600500A1 (de) * | 2004-05-27 | 2005-11-30 | Georg-August-Universität Göttingen | Methode zur Herstellung von pluripotenten Zellen aus Monozyten |
| AU2005304708B2 (en) * | 2004-11-08 | 2012-01-19 | The Johns Hopkins University | Cardiac stem cells |
| US11660317B2 (en) | 2004-11-08 | 2023-05-30 | The Johns Hopkins University | Compositions comprising cardiosphere-derived cells for use in cell therapy |
| WO2006096931A1 (en) * | 2005-03-18 | 2006-09-21 | The University Of Queensland | Renal repair and regeneration |
| US9388382B2 (en) | 2005-10-05 | 2016-07-12 | The Board Of Trustees Of The University Of Illinois | Isolation of CD14 negative, CD45 positive and CD117 positive embryonic-like stem cells free of monocytes from human umbilical cord blood mononuclear cells |
| WO2008048671A1 (en) | 2006-10-18 | 2008-04-24 | University Of Illinois | Embryonic-like stem cells derived from adult human peripheral blood and methods of use |
| ITTO20050819A1 (it) | 2005-11-18 | 2007-05-19 | Univ Degli Studi Torino | Linea cellulare staminale pluripotente, linee cellulari derivate, procedimenti per la loro produzione e relativi usi |
| WO2007131200A2 (en) * | 2006-05-05 | 2007-11-15 | Opexa Therapeutics | Monocyte-derived stem cells |
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| ITRM20060498A1 (it) * | 2006-09-20 | 2008-03-21 | Alessandra Gambacurta | Metodo di espansione di cellule staminali adulte da sangue periferico e relativi usi in campo medico |
| KR101240487B1 (ko) * | 2006-11-09 | 2013-03-08 | 더 존스 홉킨스 유니버시티 | 성체 포유동물 심근세포의 심장 줄기 세포로의 역분화 |
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| ATE479741T1 (de) * | 2007-09-21 | 2010-09-15 | Univ Leipzig | Zellkulturenmedium und verfahren zur kultivierung von stammzellen und vorläuferzellen |
| ITUD20080058A1 (it) | 2008-03-18 | 2009-09-19 | Thankstem S R L | Kit per la raccolta di sangue, preferibilmente periferico, per la produzione di cellule staminali |
| WO2009157610A1 (en) * | 2008-06-26 | 2009-12-30 | Pusan National University Industry-University Cooperation Foundation | Selenium dedifferentiated cell, preparation method and usage thereof |
| US9169463B2 (en) * | 2008-11-25 | 2015-10-27 | Otsuka Pharmaceutical Co., Ltd. | Stem cell for therapeutic use which is derived from human monocyte, and method for inducing same |
| KR100950195B1 (ko) * | 2009-03-20 | 2010-03-29 | 서울대학교산학협력단 | Znf281을 발현하는 제대혈 유래 만능 줄기세포의 분리방법 |
| US20110091433A1 (en) * | 2009-10-19 | 2011-04-21 | Ilham Mohamed Saleh Saeed Abuljadayel | Treatment using reprogrammed mature adult cells |
| PH12012500714A1 (en) * | 2009-10-19 | 2012-10-29 | Tristem Trading Cyprus Ltd | Treatment using reprogrammed mature adult cells |
| CN101760446B (zh) * | 2009-12-31 | 2012-09-12 | 浙江中赢控股集团有限公司 | 制备单核细胞型干细胞的方法及应用 |
| US9249392B2 (en) | 2010-04-30 | 2016-02-02 | Cedars-Sinai Medical Center | Methods and compositions for maintaining genomic stability in cultured stem cells |
| US9845457B2 (en) | 2010-04-30 | 2017-12-19 | Cedars-Sinai Medical Center | Maintenance of genomic stability in cultured stem cells |
| EP2603579B1 (de) * | 2010-08-12 | 2015-07-01 | ABAG Verwaltungs GmbH | Verfahren zur produktion von zellen mit den eigenschaften von hepatozyten |
| US9809798B2 (en) | 2011-03-11 | 2017-11-07 | National University Of Singapore | Pericyte progenitors from peripheral blood |
| WO2013118899A1 (ja) * | 2012-02-10 | 2013-08-15 | 医療法人社団博心厚生会 | 単球増殖剤、単球増殖用培地、単球の製造方法、樹状細胞の製造方法、及び樹状細胞ワクチンの製造方法 |
| WO2013180395A1 (ko) * | 2012-05-29 | 2013-12-05 | 한국생명공학연구원 | 다능성 줄기세포의 제작, 유지, 증식을 증진하는 대사산물 및 이를 포함하는 조성물과 배양방법 |
| US9884076B2 (en) | 2012-06-05 | 2018-02-06 | Capricor, Inc. | Optimized methods for generation of cardiac stem cells from cardiac tissue and their use in cardiac therapy |
| AU2013302799B2 (en) | 2012-08-13 | 2018-03-01 | Cedars-Sinai Medical Center | Exosomes and micro-ribonucleic acids for tissue regeneration |
| SG11201504376SA (en) * | 2012-12-06 | 2015-07-30 | Fuwan Pty Ltd | A method of generating multilineage potential cells |
| EP2862926B1 (de) | 2013-10-17 | 2018-12-05 | Centre National de la Recherche Scientifique (CNRS) | Verfahren zur in-vitro-differenzierung von blutzirkulationszellen in neuronenähnliche zellen und anwendungen davon |
| US20170007644A1 (en) * | 2013-12-06 | 2017-01-12 | Fuwan Pty Ltd. | A method of treating neoplasia |
| AU2015257334B2 (en) | 2014-05-09 | 2021-02-25 | Thankstem S.R.L. | Method for expanding adult stem cells from whole blood |
| WO2016054591A1 (en) | 2014-10-03 | 2016-04-07 | Cedars-Sinai Medical Center | Cardiosphere-derived cells and exosomes secreted by such cells in the treatment of muscular dystrophy |
| BR112017014195B1 (pt) | 2014-12-31 | 2023-04-11 | Poet Research, Inc | Processos para produzir uma corrente (slip stream) de açúcar e sistemas para produzir uma corrente (slip stream) de açúcar |
| JP7370529B2 (ja) * | 2015-08-31 | 2023-10-30 | 剛士 田邊 | 多能性幹細胞製造システム、幹細胞の誘導方法、幹細胞の浮遊培養方法、幹細胞の浮遊培養器、人工多能性幹細胞の作製方法、及び動物細胞から特定の体細胞を作製する方法 |
| US11253551B2 (en) | 2016-01-11 | 2022-02-22 | Cedars-Sinai Medical Center | Cardiosphere-derived cells and exosomes secreted by such cells in the treatment of heart failure with preserved ejection fraction |
| WO2017210652A1 (en) | 2016-06-03 | 2017-12-07 | Cedars-Sinai Medical Center | Cdc-derived exosomes for treatment of ventricular tachyarrythmias |
| EP3515459A4 (de) | 2016-09-20 | 2020-08-05 | Cedars-Sinai Medical Center | Kardiosphärenzellen und deren extrazelluläre vesikel zur verzögerung oder umkehr des alterungsprozesses und altersbedingten erkrankungen |
| CA3059910A1 (en) | 2017-04-19 | 2018-10-25 | Cedars-Sinai Medical Center | Methods and compositions for treating skeletal muscular dystrophy |
| CN107904202B (zh) * | 2017-11-22 | 2018-11-20 | 北京恩诺生物科技有限公司 | 一种制备多能干细胞样细胞的方法、组合物和应用 |
| AU2018375151B2 (en) * | 2017-11-29 | 2025-06-26 | Spinalcyte Llc | Interaction of fibroblasts and immune cells for activation and uses thereof |
| WO2019126068A1 (en) | 2017-12-20 | 2019-06-27 | Cedars-Sinai Medical Center | Engineered extracellular vesicles for enhanced tissue delivery |
| WO2019152549A1 (en) | 2018-02-05 | 2019-08-08 | Cedars-Sinai Medical Center | Methods for therapeutic use of exosomes and y-rnas |
| JP2023516484A (ja) | 2020-03-11 | 2023-04-19 | ビット バイオ リミテッド | 肝細胞作製方法 |
| JP6826744B1 (ja) * | 2020-07-17 | 2021-02-10 | 医療法人Yanaga CLinic | 成熟脂肪細胞含有組成物の製造方法 |
| EP4308183A4 (de) * | 2021-03-18 | 2025-03-12 | The University Of Sydney | Biotechnologisch hergestellte endothelialkonstrukte |
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| EP0785803A4 (de) * | 1994-09-23 | 2000-08-02 | Gen Hospital Corp | Gebrauch eines nicht-säuger dna virus zur expression eines exogenen gens in einer säugetierzelle |
| US7410773B2 (en) | 1995-02-02 | 2008-08-12 | Ghazi Jaswinder Dhoot | Method of preparing an undifferentiated cell |
| GB9502022D0 (en) * | 1995-02-02 | 1995-03-22 | Abuljadayel Ilham M S | A method for preparing lymphohaematopoietic progenitor cells |
| US7112440B2 (en) * | 1995-02-02 | 2006-09-26 | Ghazi Jaswinder Dhoot | Method of increasing the relative number of CD45 low cells in a cell population |
| US9068164B1 (en) | 1995-02-02 | 2015-06-30 | Tristem Trading (Cyprus) Limited | Method of preparing an undifferentiated cell |
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| US6043092A (en) * | 1996-03-18 | 2000-03-28 | University Of Pittsburgh | Cell culture media for mammalian cells |
| US5827740A (en) * | 1996-07-30 | 1998-10-27 | Osiris Therapeutics, Inc. | Adipogenic differentiation of human mesenchymal stem cells |
| WO1998014561A1 (en) * | 1996-10-04 | 1998-04-09 | Becton Dickinson And Company | Identification of a cd34+ bone marrow precursor for dendritic cells in blood and lymphoid tissues |
| EP0983345A1 (de) * | 1997-05-21 | 2000-03-08 | THE UNITED STATES OF AMERICA, as represented by the Secretary of the Department of Health and Human Services | Methoden und zusammensetzungen zur herstellung von dendritischen zellen aus expandierten monozyten und zur aktivierung von t-zellen |
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| US20010049139A1 (en) * | 2000-03-23 | 2001-12-06 | Eric Lagasse | Hepatic regeneration from hematopoietic stem cells |
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| US20040136973A1 (en) * | 2002-11-07 | 2004-07-15 | Eliezer Huberman | Human stem cell materials and methods |
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| EP2357223A3 (de) | 2002-11-07 | 2012-11-07 | University Of Chicago | Humane Stammzellen und Verfahren zur Verwendung |
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| US20050260158A1 (en) * | 2003-11-07 | 2005-11-24 | Eliezer Huberman | Human stem cell materials and methods |
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