ATE296642T1 - Reverse-phase zusamensetzung zur bindegewebsreparatur - Google Patents
Reverse-phase zusamensetzung zur bindegewebsreparaturInfo
- Publication number
- ATE296642T1 ATE296642T1 AT98944660T AT98944660T ATE296642T1 AT E296642 T1 ATE296642 T1 AT E296642T1 AT 98944660 T AT98944660 T AT 98944660T AT 98944660 T AT98944660 T AT 98944660T AT E296642 T1 ATE296642 T1 AT E296642T1
- Authority
- AT
- Austria
- Prior art keywords
- reverse phase
- connective tissue
- tissue repair
- phase composition
- composition
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 3
- 210000002808 connective tissue Anatomy 0.000 title abstract 2
- 230000017423 tissue regeneration Effects 0.000 title abstract 2
- RVGRUAULSDPKGF-UHFFFAOYSA-N Poloxamer Chemical compound C1CO1.CC1CO1 RVGRUAULSDPKGF-UHFFFAOYSA-N 0.000 abstract 2
- 239000000463 material Substances 0.000 abstract 2
- 230000001225 therapeutic effect Effects 0.000 abstract 2
- 210000000988 bone and bone Anatomy 0.000 abstract 1
- 229920001983 poloxamer Polymers 0.000 abstract 1
- 229960000502 poloxamer Drugs 0.000 abstract 1
- 229920001992 poloxamer 407 Polymers 0.000 abstract 1
- 229940044476 poloxamer 407 Drugs 0.000 abstract 1
- 239000000843 powder Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/3683—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment
- A61L27/3687—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment characterised by the use of chemical agents in the treatment, e.g. specific enzymes, detergents, capping agents, crosslinkers, anticalcification agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
- A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
- A61L27/227—Other specific proteins or polypeptides not covered by A61L27/222, A61L27/225 or A61L27/24
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/3604—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the human or animal origin of the biological material, e.g. hair, fascia, fish scales, silk, shellac, pericardium, pleura, renal tissue, amniotic membrane, parenchymal tissue, fetal tissue, muscle tissue, fat tissue, enamel
- A61L27/3608—Bone, e.g. demineralised bone matrix [DBM], bone powder
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/3641—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the site of application in the body
- A61L27/3645—Connective tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/3641—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the site of application in the body
- A61L27/3645—Connective tissue
- A61L27/365—Bones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/3683—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/04—Drugs for skeletal disorders for non-specific disorders of the connective tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2430/00—Materials or treatment for tissue regeneration
- A61L2430/02—Materials or treatment for tissue regeneration for reconstruction of bones; weight-bearing implants
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Dermatology (AREA)
- Epidemiology (AREA)
- Transplantation (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Botany (AREA)
- Molecular Biology (AREA)
- Vascular Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- General Chemical & Material Sciences (AREA)
- Urology & Nephrology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Physical Education & Sports Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Materials For Medical Uses (AREA)
- Golf Clubs (AREA)
- Aiming, Guidance, Guns With A Light Source, Armor, Camouflage, And Targets (AREA)
- Earth Drilling (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/922,068 US6309659B1 (en) | 1997-09-02 | 1997-09-02 | Reverse phase connective tissue repair composition |
| PCT/US1998/018150 WO1999011298A2 (en) | 1997-09-02 | 1998-09-01 | Reverse phase connective tissue repair composition |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE296642T1 true ATE296642T1 (de) | 2005-06-15 |
Family
ID=25446457
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT98944660T ATE296642T1 (de) | 1997-09-02 | 1998-09-01 | Reverse-phase zusamensetzung zur bindegewebsreparatur |
Country Status (8)
| Country | Link |
|---|---|
| US (3) | US6309659B1 (de) |
| EP (2) | EP1024839B1 (de) |
| CN (1) | CN1292712A (de) |
| AT (1) | ATE296642T1 (de) |
| AU (1) | AU9215198A (de) |
| CA (1) | CA2302195A1 (de) |
| DE (1) | DE69830417T2 (de) |
| WO (1) | WO1999011298A2 (de) |
Families Citing this family (93)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6309659B1 (en) * | 1997-09-02 | 2001-10-30 | Gensci Orthobiologics, Inc. | Reverse phase connective tissue repair composition |
| US6326018B1 (en) | 1998-02-27 | 2001-12-04 | Musculoskeletal Transplant Foundation | Flexible sheet of demineralized bone |
| US6458375B1 (en) | 1998-02-27 | 2002-10-01 | Musculoskeletal Transplant Foundation | Malleable paste with allograft bone reinforcement for filling bone defects |
| US6437018B1 (en) | 1998-02-27 | 2002-08-20 | Musculoskeletal Transplant Foundation | Malleable paste with high molecular weight buffered carrier for filling bone defects |
| US6030635A (en) * | 1998-02-27 | 2000-02-29 | Musculoskeletal Transplant Foundation | Malleable paste for filling bone defects |
| USRE38522E1 (en) | 1998-02-27 | 2004-05-25 | Musculoskeletal Transplant Foundation | Malleable paste for filling bone defects |
| US6132685A (en) | 1998-08-10 | 2000-10-17 | Caliper Technologies Corporation | High throughput microfluidic systems and methods |
| US9616150B2 (en) * | 1999-10-29 | 2017-04-11 | Children's Hospital Los Angeles | Bone hemostasis method and materials |
| AU784006B2 (en) * | 2000-01-21 | 2006-01-12 | Musculoskeletal Transplant Foundation | Malleable paste for filling bone defects |
| EP1456278B1 (de) * | 2001-12-21 | 2006-03-08 | IsoTis Orthobiologics, Inc. | Zusammensetzungen enthaltend endgruppen-verkappte polyalkylenglykole |
| US7205337B2 (en) * | 2001-12-21 | 2007-04-17 | Isotis Orthobiologics, Inc. | End-capped polymers and compositions containing such compounds |
| WO2003080119A1 (en) * | 2002-03-26 | 2003-10-02 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Responsive biomedical composites |
| EP1531859A4 (de) * | 2002-05-31 | 2005-12-07 | Univ Jefferson | Zusammensetzungen und verfahren für den transepithelialen molekültransport |
| WO2004022120A1 (en) * | 2002-09-04 | 2004-03-18 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Compositions comprising bone marrow cells, demineralized bone matrix and rtg polymers for use in the induction of bone and cartilage formation |
| ES2535484T3 (es) * | 2002-12-12 | 2015-05-12 | Warsaw Orthopedic, Inc. | Material compuesto de polímero-hueso que se puede formar o configurar y método para su producción |
| EP1596767B1 (de) | 2003-02-12 | 2018-10-03 | Syncera, Inc. | Statistische und nichtstatistische alkylenoxid-polymer-legierungszusammensetzungen |
| US7067123B2 (en) | 2003-04-29 | 2006-06-27 | Musculoskeletal Transplant Foundation | Glue for cartilage repair |
| IL155866A0 (en) * | 2003-05-12 | 2003-12-23 | Yissum Res Dev Co | Responsive polymeric system |
| US7901457B2 (en) | 2003-05-16 | 2011-03-08 | Musculoskeletal Transplant Foundation | Cartilage allograft plug |
| US7488348B2 (en) | 2003-05-16 | 2009-02-10 | Musculoskeletal Transplant Foundation | Cartilage allograft plug |
| US20050020506A1 (en) * | 2003-07-25 | 2005-01-27 | Drapeau Susan J. | Crosslinked compositions comprising collagen and demineralized bone matrix, methods of making and methods of use |
| US7837740B2 (en) | 2007-01-24 | 2010-11-23 | Musculoskeletal Transplant Foundation | Two piece cancellous construct for cartilage repair |
| US20060110357A1 (en) * | 2004-11-22 | 2006-05-25 | Materna Peter A | Bone putty composition that maintains granule suspension at reduced temperatures |
| US20060233849A1 (en) * | 2005-04-13 | 2006-10-19 | Simon Bruce J | Composite bone graft material |
| US7621963B2 (en) * | 2005-04-13 | 2009-11-24 | Ebi, Llc | Composite bone graft material |
| US7815926B2 (en) | 2005-07-11 | 2010-10-19 | Musculoskeletal Transplant Foundation | Implant for articular cartilage repair |
| JP2009508596A (ja) | 2005-09-19 | 2009-03-05 | ヒストジェニックス コーポレイション | 細胞支持基材及びその調製方法 |
| US9132208B2 (en) * | 2008-08-07 | 2015-09-15 | Lifenet Health | Composition for a tissue repair implant and methods of making the same |
| US9005646B2 (en) | 2005-10-12 | 2015-04-14 | Lifenet Health | Compositions for repair of defects in tissues, and methods of making the same |
| US8784477B2 (en) | 2011-01-05 | 2014-07-22 | Abbott Cardiovascular Systems Inc. | Stent graft with two layer ePTFE layer system with high plasticity and high rigidity |
| US7785634B2 (en) * | 2006-02-27 | 2010-08-31 | Globus Medical, Inc. | Bone graft materials derived from mineralized gelatin |
| US7892577B2 (en) * | 2006-02-27 | 2011-02-22 | Globus Medical, Inc. | Bone graft materials derived from mineralized gelatin |
| CA2646486A1 (en) * | 2006-03-23 | 2007-09-27 | Citagenix Inc. | Reverse phase osteoconductive composition |
| US20100209470A1 (en) * | 2006-05-01 | 2010-08-19 | Warsaw Orthopedic, Inc. An Indiana Corporation | Demineralized bone matrix devices |
| US8506983B2 (en) * | 2006-05-01 | 2013-08-13 | Warsaw Orthopedic, Inc. | Bone filler material |
| US7838022B2 (en) * | 2006-05-01 | 2010-11-23 | Warsaw Orthopedic, Inc | Malleable implants containing demineralized bone matrix |
| US7771741B2 (en) * | 2006-05-01 | 2010-08-10 | Warsaw Orthopedic, Inc | Demineralized bone matrix devices |
| US7943683B2 (en) | 2006-12-01 | 2011-05-17 | Tepha, Inc. | Medical devices containing oriented films of poly-4-hydroxybutyrate and copolymers |
| US8435551B2 (en) | 2007-03-06 | 2013-05-07 | Musculoskeletal Transplant Foundation | Cancellous construct with support ring for repair of osteochondral defects |
| US9132296B2 (en) | 2007-05-17 | 2015-09-15 | Ag Essence | Antimicrobial solution and methods of making and using the same |
| US9138509B2 (en) * | 2007-09-14 | 2015-09-22 | Musculoskeletal Transplant Foundation | Composition for filling bone defects |
| US8501230B2 (en) * | 2007-12-03 | 2013-08-06 | Trilogic Pharma Llc | Self solidifying bioerodible barrier implant |
| US9056150B2 (en) * | 2007-12-04 | 2015-06-16 | Warsaw Orthopedic, Inc. | Compositions for treating bone defects |
| US8287909B2 (en) * | 2007-12-19 | 2012-10-16 | Tepha, Inc. | Medical devices containing melt-blown non-wovens of poly-4-hydroxybutyrate and copolymers thereof |
| WO2009111069A1 (en) | 2008-03-05 | 2009-09-11 | Musculoskeletal Transplant Foundation | Cancellous constructs, cartilage particles and combinations of cancellous constructs and cartilage particles |
| US8840913B2 (en) | 2008-03-27 | 2014-09-23 | Warsaw Orthopedic, Inc. | Malleable multi-component implants and materials therefor |
| PT2558133T (pt) | 2010-03-26 | 2020-04-23 | Tepha Inc | Revestimentos para o fabrico e aplicação de dispositivos médicos de polihidroxialcanqato |
| US9511169B2 (en) | 2010-06-15 | 2016-12-06 | Tepha, Inc. | Medical devices containing dry spun non-wovens of poly-4-hydroxybutyrate and copolymers with anisotropic properties |
| US10227718B2 (en) | 2010-06-15 | 2019-03-12 | Tepha, Inc. | Medical devices containing dry spun non-wovens of poly-4-hydroxybutyrate and copolymers |
| ES2644478T3 (es) | 2010-11-09 | 2017-11-29 | Tepha, Inc. | Implantes cocleares liberadores de fármacos |
| WO2012117260A1 (en) | 2011-03-03 | 2012-09-07 | Orthos Limited | Product |
| WO2013049161A1 (en) | 2011-09-27 | 2013-04-04 | Tepha, Inc. | Controlled hydrolysis of poly-4-hydroxybutyrate and copolymers |
| EP2852417B1 (de) | 2012-05-21 | 2019-06-12 | Tepha, Inc. | Resorbierbare biokeramische zusammensetzungen aus poly-4-hydroxybutyrat und copolymeren |
| US10207027B2 (en) | 2012-06-11 | 2019-02-19 | Globus Medical, Inc. | Bioactive bone graft substitutes |
| WO2014049667A1 (ja) * | 2012-09-28 | 2014-04-03 | 株式会社島津製作所 | デジタル画像処理方法および撮影装置 |
| WO2014099967A1 (en) * | 2012-12-18 | 2014-06-26 | Novabone Products, Llc | Bioactive glass with ethylene oxide propylene oxide block copolymers |
| ES2751398T3 (es) | 2013-01-15 | 2020-03-31 | Tepha Inc | Implantes para regeneración de tejido blando y tejido duro |
| US9290612B2 (en) | 2013-03-13 | 2016-03-22 | Tepha, Inc. | Compositions and devices of poly-4-hydroxybutyrate |
| US10201640B2 (en) | 2013-03-13 | 2019-02-12 | Tepha, Inc. | Ultrafine electrospun fibers of poly-4-hydroxybutyrate and copolymers thereof |
| ES2878122T3 (es) | 2013-08-20 | 2021-11-18 | Tepha Inc | Espumas de celda cerrada que incluyen poli-4-hidroxibutirato y copolímeros del mismo |
| US9687585B2 (en) | 2013-08-20 | 2017-06-27 | Tepha, Inc. | Thermoformed poly-4-hydroxybutyrate medical implants |
| US9539286B2 (en) | 2013-10-18 | 2017-01-10 | Globus Medical, Inc. | Bone grafts including osteogenic stem cells, and methods relating to the same |
| US9486483B2 (en) | 2013-10-18 | 2016-11-08 | Globus Medical, Inc. | Bone grafts including osteogenic stem cells, and methods relating to the same |
| US9480780B2 (en) | 2013-11-05 | 2016-11-01 | Tepha, Inc. | Compositions and devices of poly-4-hydroxybutyrate |
| ES2834498T3 (es) | 2013-12-26 | 2021-06-17 | Tepha Inc | Implantes médicos que incluyen laminados de poli-4-hidroxibutirato y copolímeros del mismo |
| US9579421B2 (en) | 2014-02-07 | 2017-02-28 | Globus Medical Inc. | Bone grafts and methods of making and using bone grafts |
| US9463264B2 (en) | 2014-02-11 | 2016-10-11 | Globus Medical, Inc. | Bone grafts and methods of making and using bone grafts |
| US9895465B2 (en) | 2014-03-12 | 2018-02-20 | Pioneer Surgical Technology, Inc. | Absorbable compositions and methods for their use in hemostasis |
| EP3119930B1 (de) | 2014-03-18 | 2018-06-13 | Tepha, Inc. | Micro-faserbahnen von poly-4-hydroxybutyrat und copolymere davon durch zentrifugenspinnen hergestellt |
| EP3137015B1 (de) | 2014-04-30 | 2022-01-26 | Tepha, Inc. | Dreidimensionale resorbierbare implantate zur gewebeverstärkung und herniereparatur |
| ES2674807T3 (es) | 2014-05-16 | 2018-07-04 | Tepha, Inc. | Dispositivos médicos que contienen materiales no tejidos hilados en seco de poli-4-hidroxibutirato y copolímeros con propiedades anisótropas |
| EP3180040B1 (de) | 2014-08-15 | 2020-05-13 | Tepha, Inc. | Selbsthaltendes chirurgisches nahtmaterial aus poly-4-hydroxybutyrat und copolymeren davon |
| EP3183012B1 (de) | 2014-08-20 | 2017-12-20 | Tepha, Inc. | Thermogeformte medizinische poly-4-hydroxybutyrat-implantate |
| US10077420B2 (en) | 2014-12-02 | 2018-09-18 | Histogenics Corporation | Cell and tissue culture container |
| US10626521B2 (en) | 2014-12-11 | 2020-04-21 | Tepha, Inc. | Methods of manufacturing mesh sutures from poly-4-hydroxybutyrate and copolymers thereof |
| WO2016094669A1 (en) | 2014-12-11 | 2016-06-16 | Tepha, Inc. | Methods of orienting multifilament yarn and monofilaments of poly-4-hydroxybutyrate and copolymers thereof |
| CA2986702C (en) | 2015-05-21 | 2023-04-04 | David Wang | Modified demineralized cortical bone fibers |
| US10016529B2 (en) | 2015-06-10 | 2018-07-10 | Globus Medical, Inc. | Biomaterial compositions, implants, and methods of making the same |
| US11426489B2 (en) | 2015-06-10 | 2022-08-30 | Globus Medical, Inc. | Biomaterial compositions, implants, and methods of making the same |
| US10743996B2 (en) | 2017-03-24 | 2020-08-18 | Robert L. Bundy | Amnion putty for cartilage repair |
| US11040170B2 (en) | 2017-05-25 | 2021-06-22 | Tepha, Inc. | Continuous formation of tubes of poly-4-hydroxybutyrate and copolymers thereof |
| WO2019050936A1 (en) | 2017-09-06 | 2019-03-14 | Tepha, Inc. | CALANDERATED SURGICAL TRELLIS COMPRISING POLYHYDROXYALKANOATES |
| EP3720514B1 (de) | 2017-12-04 | 2022-04-13 | Tepha, Inc. | Vakuummembran-thermogeformte medizinische poly-4-hydroxybutyrat-implantate |
| EP3735204B1 (de) | 2018-01-02 | 2023-09-06 | Cartiheal (2009) Ltd. | Implantationswerkzeug für optimierte solide substrate zur förderung von zell- und gewebewachstum |
| EP4442767A3 (de) | 2018-06-11 | 2025-01-22 | Tepha, Inc. | Verfahren zum 3d-drucken von poly-4-hydroxybutyrat |
| ES2956815T3 (es) | 2018-10-29 | 2023-12-28 | Tepha Inc | Procedimientos de fabricación de suturas de malla a partir de poli-4-hidroxibutirato y sus copolímeros |
| US11207445B2 (en) | 2019-07-09 | 2021-12-28 | Community Blood Center | Allograft bone putty and methods of making the same |
| FR3109290B1 (fr) | 2020-04-17 | 2025-04-11 | Ph Tech | Dispositif médical comprenant une matrice biologique acellulaire et au moins un polymère |
| FR3110077B1 (fr) | 2020-05-12 | 2024-12-06 | Ph Tech | Procédé de fabrication d’un dispositif médical en trois dimensions et dispositif médical obtenu |
| US11896736B2 (en) | 2020-07-13 | 2024-02-13 | Globus Medical, Inc | Biomaterial implants and methods of making the same |
| FR3113371A1 (fr) | 2020-08-12 | 2022-02-18 | Ph Tech | Dispositif médical comprenant un assemblage d’éléments de matrices biologiques acellulaires et au moins un polymère |
| JP2024510182A (ja) | 2021-03-11 | 2024-03-06 | テファ, インコーポレイテッド | 乳房再建インプラント |
| FR3165166A1 (fr) | 2024-08-05 | 2026-02-06 | Ph Tech | Utilisation de l’Éther de dipropylène glycol monométhylique pour purifier un biomatériau |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4394370A (en) * | 1981-09-21 | 1983-07-19 | Jefferies Steven R | Bone graft material for osseous defects and method of making same |
| US4472840A (en) * | 1981-09-21 | 1984-09-25 | Jefferies Steven R | Method of inducing osseous formation by implanting bone graft material |
| US4722948A (en) * | 1984-03-16 | 1988-02-02 | Dynatech Corporation | Bone replacement and repair putty material from unsaturated polyester resin and vinyl pyrrolidone |
| US6110737A (en) * | 1988-02-02 | 2000-08-29 | The Regents Of The University Of California | Human platelet-derived growth factor receptor, type A |
| US5290558A (en) | 1989-09-21 | 1994-03-01 | Osteotech, Inc. | Flowable demineralized bone powder composition and its use in bone repair |
| US5073373A (en) * | 1989-09-21 | 1991-12-17 | Osteotech, Inc. | Flowable demineralized bone powder composition and its use in bone repair |
| US5693615A (en) * | 1991-06-05 | 1997-12-02 | The Procter & Gamble Company | Therapeutic compositions for osteoinduction |
| US5356629A (en) * | 1991-07-12 | 1994-10-18 | United States Surgical Corporation | Composition for effecting bone repair |
| EP0551626A1 (de) | 1991-12-19 | 1993-07-21 | LEK, tovarna farmacevtskih in kemicnih izdelkov, d.d. | Thermoreversible Gel als pharmazeutische Grundmasse für eine galenische Form |
| US5503558A (en) | 1993-11-12 | 1996-04-02 | Mcgill University | Osseointegration promoting implant composition, implant assembly and method therefor |
| US5817327A (en) * | 1994-07-27 | 1998-10-06 | The Trustees Of The University Of Pennsylvania | Incorporation of biologically active molecules into bioactive glasses |
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| US5707962A (en) * | 1994-09-28 | 1998-01-13 | Gensci Regeneration Sciences Inc. | Compositions with enhanced osteogenic potential, method for making the same and therapeutic uses thereof |
| US5580923A (en) * | 1995-03-14 | 1996-12-03 | Collagen Corporation | Anti-adhesion films and compositions for medical use |
| JPH09143093A (ja) | 1995-11-17 | 1997-06-03 | Hoechst Japan Ltd | 軟骨・骨誘導性修復用材料 |
| US7026292B1 (en) * | 1995-12-12 | 2006-04-11 | Stryker Corporation | Compositions and therapeutic methods using morphogenic proteins and stimulatory factors |
| US5733868A (en) * | 1996-04-16 | 1998-03-31 | Depuy Orthopaedics, Inc. | Poly(amino acid) adhesive tissue grafts |
| SG60017A1 (en) * | 1996-09-25 | 1999-02-22 | Nat Univerisity Of Singapore | Method of preparing filler containing forms of chitin |
| US6309659B1 (en) * | 1997-09-02 | 2001-10-30 | Gensci Orthobiologics, Inc. | Reverse phase connective tissue repair composition |
| US6030635A (en) | 1998-02-27 | 2000-02-29 | Musculoskeletal Transplant Foundation | Malleable paste for filling bone defects |
-
1997
- 1997-09-02 US US08/922,068 patent/US6309659B1/en not_active Expired - Lifetime
-
1998
- 1998-09-01 DE DE69830417T patent/DE69830417T2/de not_active Expired - Lifetime
- 1998-09-01 EP EP98944660A patent/EP1024839B1/de not_active Expired - Lifetime
- 1998-09-01 CN CN988140039A patent/CN1292712A/zh active Pending
- 1998-09-01 AU AU92151/98A patent/AU9215198A/en not_active Abandoned
- 1998-09-01 CA CA002302195A patent/CA2302195A1/en not_active Abandoned
- 1998-09-01 EP EP05075353A patent/EP1537882A1/de not_active Ceased
- 1998-09-01 WO PCT/US1998/018150 patent/WO1999011298A2/en not_active Ceased
- 1998-09-01 AT AT98944660T patent/ATE296642T1/de not_active IP Right Cessation
-
2001
- 2001-08-27 US US09/939,898 patent/US6623748B2/en not_active Expired - Lifetime
-
2003
- 2003-07-28 US US10/628,147 patent/US20040022858A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| EP1024839A2 (de) | 2000-08-09 |
| US20040022858A1 (en) | 2004-02-05 |
| EP1024839B1 (de) | 2005-06-01 |
| WO1999011298A2 (en) | 1999-03-11 |
| DE69830417T2 (de) | 2006-01-26 |
| EP1537882A1 (de) | 2005-06-08 |
| AU9215198A (en) | 1999-03-22 |
| US6309659B1 (en) | 2001-10-30 |
| WO1999011298A3 (en) | 1999-06-17 |
| DE69830417D1 (de) | 2005-07-07 |
| CN1292712A (zh) | 2001-04-25 |
| CA2302195A1 (en) | 1999-03-11 |
| US20020034531A1 (en) | 2002-03-21 |
| US6623748B2 (en) | 2003-09-23 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |