ATE296642T1 - Reverse-phase zusamensetzung zur bindegewebsreparatur - Google Patents
Reverse-phase zusamensetzung zur bindegewebsreparaturInfo
- Publication number
- ATE296642T1 ATE296642T1 AT98944660T AT98944660T ATE296642T1 AT E296642 T1 ATE296642 T1 AT E296642T1 AT 98944660 T AT98944660 T AT 98944660T AT 98944660 T AT98944660 T AT 98944660T AT E296642 T1 ATE296642 T1 AT E296642T1
- Authority
- AT
- Austria
- Prior art keywords
- reverse phase
- connective tissue
- tissue repair
- phase composition
- composition
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 3
- 210000002808 connective tissue Anatomy 0.000 title abstract 2
- 230000017423 tissue regeneration Effects 0.000 title abstract 2
- RVGRUAULSDPKGF-UHFFFAOYSA-N Poloxamer Chemical compound C1CO1.CC1CO1 RVGRUAULSDPKGF-UHFFFAOYSA-N 0.000 abstract 2
- 239000000463 material Substances 0.000 abstract 2
- 230000001225 therapeutic effect Effects 0.000 abstract 2
- 210000000988 bone and bone Anatomy 0.000 abstract 1
- 229920001983 poloxamer Polymers 0.000 abstract 1
- 229960000502 poloxamer Drugs 0.000 abstract 1
- 229920001992 poloxamer 407 Polymers 0.000 abstract 1
- 229940044476 poloxamer 407 Drugs 0.000 abstract 1
- 239000000843 powder Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/3683—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment
- A61L27/3687—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment characterised by the use of chemical agents in the treatment, e.g. specific enzymes, detergents, capping agents, crosslinkers, anticalcification agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
- A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
- A61L27/227—Other specific proteins or polypeptides not covered by A61L27/222, A61L27/225 or A61L27/24
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/3604—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the human or animal origin of the biological material, e.g. hair, fascia, fish scales, silk, shellac, pericardium, pleura, renal tissue, amniotic membrane, parenchymal tissue, fetal tissue, muscle tissue, fat tissue, enamel
- A61L27/3608—Bone, e.g. demineralised bone matrix [DBM], bone powder
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/3641—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the site of application in the body
- A61L27/3645—Connective tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/3641—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the site of application in the body
- A61L27/3645—Connective tissue
- A61L27/365—Bones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/3683—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/04—Drugs for skeletal disorders for non-specific disorders of the connective tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2430/00—Materials or treatment for tissue regeneration
- A61L2430/02—Materials or treatment for tissue regeneration for reconstruction of bones; weight-bearing implants
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Dermatology (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Transplantation (AREA)
- Epidemiology (AREA)
- Botany (AREA)
- Molecular Biology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Vascular Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Urology & Nephrology (AREA)
- Zoology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Physical Education & Sports Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Materials For Medical Uses (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Golf Clubs (AREA)
- Aiming, Guidance, Guns With A Light Source, Armor, Camouflage, And Targets (AREA)
- Earth Drilling (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/922,068 US6309659B1 (en) | 1997-09-02 | 1997-09-02 | Reverse phase connective tissue repair composition |
| PCT/US1998/018150 WO1999011298A2 (en) | 1997-09-02 | 1998-09-01 | Reverse phase connective tissue repair composition |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE296642T1 true ATE296642T1 (de) | 2005-06-15 |
Family
ID=25446457
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT98944660T ATE296642T1 (de) | 1997-09-02 | 1998-09-01 | Reverse-phase zusamensetzung zur bindegewebsreparatur |
Country Status (8)
| Country | Link |
|---|---|
| US (3) | US6309659B1 (de) |
| EP (2) | EP1537882A1 (de) |
| CN (1) | CN1292712A (de) |
| AT (1) | ATE296642T1 (de) |
| AU (1) | AU9215198A (de) |
| CA (1) | CA2302195A1 (de) |
| DE (1) | DE69830417T2 (de) |
| WO (1) | WO1999011298A2 (de) |
Families Citing this family (93)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6309659B1 (en) * | 1997-09-02 | 2001-10-30 | Gensci Orthobiologics, Inc. | Reverse phase connective tissue repair composition |
| US6458375B1 (en) | 1998-02-27 | 2002-10-01 | Musculoskeletal Transplant Foundation | Malleable paste with allograft bone reinforcement for filling bone defects |
| US6437018B1 (en) | 1998-02-27 | 2002-08-20 | Musculoskeletal Transplant Foundation | Malleable paste with high molecular weight buffered carrier for filling bone defects |
| USRE38522E1 (en) | 1998-02-27 | 2004-05-25 | Musculoskeletal Transplant Foundation | Malleable paste for filling bone defects |
| US6326018B1 (en) | 1998-02-27 | 2001-12-04 | Musculoskeletal Transplant Foundation | Flexible sheet of demineralized bone |
| US6030635A (en) * | 1998-02-27 | 2000-02-29 | Musculoskeletal Transplant Foundation | Malleable paste for filling bone defects |
| US6132685A (en) | 1998-08-10 | 2000-10-17 | Caliper Technologies Corporation | High throughput microfluidic systems and methods |
| US9616150B2 (en) * | 1999-10-29 | 2017-04-11 | Children's Hospital Los Angeles | Bone hemostasis method and materials |
| AU784006B2 (en) * | 2000-01-21 | 2006-01-12 | Musculoskeletal Transplant Foundation | Malleable paste for filling bone defects |
| ATE319760T1 (de) * | 2001-12-21 | 2006-03-15 | Isotis Orthobiologics Inc | Zusammensetzungen enthaltend endgruppen-verkappte polyalkylenglykole |
| US7205337B2 (en) * | 2001-12-21 | 2007-04-17 | Isotis Orthobiologics, Inc. | End-capped polymers and compositions containing such compounds |
| WO2003080119A1 (en) * | 2002-03-26 | 2003-10-02 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Responsive biomedical composites |
| NZ537120A (en) * | 2002-05-31 | 2008-07-31 | Univ Jefferson | Compositions and methods for transepithelial molecular transport |
| AU2002337479A1 (en) * | 2002-09-04 | 2004-03-29 | Hadasit Medical Research Services & Development Ltd. | Compositions comprising bone marrow cells, demineralized bone matrix and rtg polymers for use in the induction of bone and cartilage formation |
| KR20050088380A (ko) * | 2002-12-12 | 2005-09-05 | 오스테오테크, 인코포레이티드 | 성형 가능하며 고정 가능한 폴리머 뼈 복합재료 및 그 제조방법 |
| AU2004211991B2 (en) * | 2003-02-12 | 2011-03-31 | Syncera, Inc. | Random and non-random alkylene oxide polymer alloy compositions |
| US7067123B2 (en) | 2003-04-29 | 2006-06-27 | Musculoskeletal Transplant Foundation | Glue for cartilage repair |
| IL155866A0 (en) * | 2003-05-12 | 2003-12-23 | Yissum Res Dev Co | Responsive polymeric system |
| US7901457B2 (en) | 2003-05-16 | 2011-03-08 | Musculoskeletal Transplant Foundation | Cartilage allograft plug |
| US7488348B2 (en) | 2003-05-16 | 2009-02-10 | Musculoskeletal Transplant Foundation | Cartilage allograft plug |
| US20050020506A1 (en) * | 2003-07-25 | 2005-01-27 | Drapeau Susan J. | Crosslinked compositions comprising collagen and demineralized bone matrix, methods of making and methods of use |
| US7837740B2 (en) | 2007-01-24 | 2010-11-23 | Musculoskeletal Transplant Foundation | Two piece cancellous construct for cartilage repair |
| US20060110357A1 (en) * | 2004-11-22 | 2006-05-25 | Materna Peter A | Bone putty composition that maintains granule suspension at reduced temperatures |
| US20060233849A1 (en) * | 2005-04-13 | 2006-10-19 | Simon Bruce J | Composite bone graft material |
| US7621963B2 (en) * | 2005-04-13 | 2009-11-24 | Ebi, Llc | Composite bone graft material |
| US7815926B2 (en) | 2005-07-11 | 2010-10-19 | Musculoskeletal Transplant Foundation | Implant for articular cartilage repair |
| CA2623106C (en) | 2005-09-19 | 2013-12-24 | Histogenics Corporation | Cell-support matrix having narrowly defined uniformly vertically and non-randomly organized porosity and pore density and a method for preparation thereof |
| US9132208B2 (en) * | 2008-08-07 | 2015-09-15 | Lifenet Health | Composition for a tissue repair implant and methods of making the same |
| US9005646B2 (en) | 2005-10-12 | 2015-04-14 | Lifenet Health | Compositions for repair of defects in tissues, and methods of making the same |
| US7892577B2 (en) | 2006-02-27 | 2011-02-22 | Globus Medical, Inc. | Bone graft materials derived from mineralized gelatin |
| US7785634B2 (en) * | 2006-02-27 | 2010-08-31 | Globus Medical, Inc. | Bone graft materials derived from mineralized gelatin |
| US8784477B2 (en) | 2011-01-05 | 2014-07-22 | Abbott Cardiovascular Systems Inc. | Stent graft with two layer ePTFE layer system with high plasticity and high rigidity |
| WO2007107012A1 (en) * | 2006-03-23 | 2007-09-27 | Citagenix Inc. | Reverse phase osteoconductive composition |
| US20100209470A1 (en) * | 2006-05-01 | 2010-08-19 | Warsaw Orthopedic, Inc. An Indiana Corporation | Demineralized bone matrix devices |
| US7771741B2 (en) * | 2006-05-01 | 2010-08-10 | Warsaw Orthopedic, Inc | Demineralized bone matrix devices |
| US7838022B2 (en) | 2006-05-01 | 2010-11-23 | Warsaw Orthopedic, Inc | Malleable implants containing demineralized bone matrix |
| US8506983B2 (en) * | 2006-05-01 | 2013-08-13 | Warsaw Orthopedic, Inc. | Bone filler material |
| US7943683B2 (en) | 2006-12-01 | 2011-05-17 | Tepha, Inc. | Medical devices containing oriented films of poly-4-hydroxybutyrate and copolymers |
| US8435551B2 (en) | 2007-03-06 | 2013-05-07 | Musculoskeletal Transplant Foundation | Cancellous construct with support ring for repair of osteochondral defects |
| US9132296B2 (en) | 2007-05-17 | 2015-09-15 | Ag Essence | Antimicrobial solution and methods of making and using the same |
| US9138509B2 (en) * | 2007-09-14 | 2015-09-22 | Musculoskeletal Transplant Foundation | Composition for filling bone defects |
| EP2219608B1 (de) * | 2007-12-03 | 2014-03-19 | Trilogic Pharma Llc | Selbstverfestigendes bioerodierbares barriereimplantat |
| US9056150B2 (en) * | 2007-12-04 | 2015-06-16 | Warsaw Orthopedic, Inc. | Compositions for treating bone defects |
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| CA2717725A1 (en) | 2008-03-05 | 2009-09-11 | Musculoskeletal Transplant Foundation | Cancellous constructs, cartilage particles and combinations of cancellous constructs and cartilage particles |
| US8840913B2 (en) * | 2008-03-27 | 2014-09-23 | Warsaw Orthopedic, Inc. | Malleable multi-component implants and materials therefor |
| EP2558133B1 (de) | 2010-03-26 | 2020-01-22 | Tepha, Inc. | Beschichtungen für die herstellung und anwendung von medizinischen polyhydroxyalkanoatvorrichtungen |
| US9511169B2 (en) | 2010-06-15 | 2016-12-06 | Tepha, Inc. | Medical devices containing dry spun non-wovens of poly-4-hydroxybutyrate and copolymers with anisotropic properties |
| EP2582866B1 (de) | 2010-06-15 | 2014-09-17 | Tepha, Inc. | Medizinprodukte mit trockengesponnen vliesstoffe aus poly-4-hydroxybutyrat und copolymere |
| EP2637734B1 (de) | 2010-11-09 | 2017-09-13 | Tepha, Inc. | Wirkstoffabgebende cochleaimplantate |
| US20140030338A1 (en) * | 2011-03-03 | 2014-01-30 | Spineart Sa | Product |
| EP3266806A1 (de) | 2011-09-27 | 2018-01-10 | Tepha, Inc. | Verfahren zur herstellung eines gegenstands enthaltend poly-4-hydroxybutyrat oder ein copolymer davon |
| EP2852417B1 (de) | 2012-05-21 | 2019-06-12 | Tepha, Inc. | Resorbierbare biokeramische zusammensetzungen aus poly-4-hydroxybutyrat und copolymeren |
| US10207027B2 (en) | 2012-06-11 | 2019-02-19 | Globus Medical, Inc. | Bioactive bone graft substitutes |
| WO2014049667A1 (ja) * | 2012-09-28 | 2014-04-03 | 株式会社島津製作所 | デジタル画像処理方法および撮影装置 |
| US20150283296A1 (en) * | 2012-12-18 | 2015-10-08 | Novabone Products Llc | Bioactive glass with ethylene oxide proplyene oxide block copolymers |
| US10149923B2 (en) | 2013-01-15 | 2018-12-11 | Tepha, Inc. | Implants for soft and hard tissue regeneration |
| US10201640B2 (en) | 2013-03-13 | 2019-02-12 | Tepha, Inc. | Ultrafine electrospun fibers of poly-4-hydroxybutyrate and copolymers thereof |
| US9290612B2 (en) | 2013-03-13 | 2016-03-22 | Tepha, Inc. | Compositions and devices of poly-4-hydroxybutyrate |
| US9687585B2 (en) | 2013-08-20 | 2017-06-27 | Tepha, Inc. | Thermoformed poly-4-hydroxybutyrate medical implants |
| US10689498B2 (en) | 2013-08-20 | 2020-06-23 | Tepha, Inc. | Closed cell foams including poly-4-hydroxybutyrate and copolymers thereof |
| US9539286B2 (en) | 2013-10-18 | 2017-01-10 | Globus Medical, Inc. | Bone grafts including osteogenic stem cells, and methods relating to the same |
| US9486483B2 (en) | 2013-10-18 | 2016-11-08 | Globus Medical, Inc. | Bone grafts including osteogenic stem cells, and methods relating to the same |
| US9480780B2 (en) | 2013-11-05 | 2016-11-01 | Tepha, Inc. | Compositions and devices of poly-4-hydroxybutyrate |
| WO2015100120A1 (en) | 2013-12-26 | 2015-07-02 | Tepha, Inc. | Medical implants including laminates of poly-4-hydroxybutyrate and copolymers thereof |
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| US9895465B2 (en) * | 2014-03-12 | 2018-02-20 | Pioneer Surgical Technology, Inc. | Absorbable compositions and methods for their use in hemostasis |
| ES2685963T3 (es) | 2014-03-18 | 2018-10-15 | Tepha, Inc. | Bandas de microfibras de poli-4-hidroxibutirato y sus copolímeros producidas por hilado centrífugo |
| US10335257B2 (en) | 2014-04-30 | 2019-07-02 | Tepha, Inc. | Three-dimensional resorbable implants for tissue reinforcement and hernia repair |
| ES2674807T3 (es) | 2014-05-16 | 2018-07-04 | Tepha, Inc. | Dispositivos médicos que contienen materiales no tejidos hilados en seco de poli-4-hidroxibutirato y copolímeros con propiedades anisótropas |
| US10500303B2 (en) | 2014-08-15 | 2019-12-10 | Tepha, Inc. | Self-retaining sutures of poly-4-hydroxybutyrate and copolymers thereof |
| ES2661648T3 (es) | 2014-08-20 | 2018-04-02 | Tepha, Inc. | Implantes médicos de poli-4-hidroxibutirato termoformados |
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| US10626521B2 (en) | 2014-12-11 | 2020-04-21 | Tepha, Inc. | Methods of manufacturing mesh sutures from poly-4-hydroxybutyrate and copolymers thereof |
| EP3230500B1 (de) | 2014-12-11 | 2025-06-18 | Tepha, Inc. | Verfahren zum orientieren von multifilamentgarn und monofilamente aus poly-4-hydroxybutyrat und copolymere davon |
| EP3297694A1 (de) | 2015-05-21 | 2018-03-28 | Musculoskeletal Transplant Foundation | Modifizierte demineralisierte kortikale knochenfasern |
| US10016529B2 (en) | 2015-06-10 | 2018-07-10 | Globus Medical, Inc. | Biomaterial compositions, implants, and methods of making the same |
| US11426489B2 (en) | 2015-06-10 | 2022-08-30 | Globus Medical, Inc. | Biomaterial compositions, implants, and methods of making the same |
| US10743996B2 (en) * | 2017-03-24 | 2020-08-18 | Robert L. Bundy | Amnion putty for cartilage repair |
| EP3630445B1 (de) | 2017-05-25 | 2022-11-30 | Tepha, Inc. | Kontinuierliche herstellung von rohren aus poly-4-hydroxybutyrat und copolymeren davon |
| CA3074733C (en) | 2017-09-06 | 2022-06-21 | Tepha, Inc. | Calendered surgical meshes comprising polyhydroxyalkanoates |
| EP3720514B1 (de) | 2017-12-04 | 2022-04-13 | Tepha, Inc. | Vakuummembran-thermogeformte medizinische poly-4-hydroxybutyrat-implantate |
| IL275811B2 (en) | 2018-01-02 | 2025-05-01 | Cartiheal 2009 Ltd | A tool and protocol for optimal implantation of a solid implant that promotes cell and tissue growth |
| CA3102277C (en) | 2018-06-11 | 2024-11-12 | Tepha, Inc. | PROCESSES FOR 3D PRINTING POLY-4-HYDROXYBUTYRATE AND COPOLYMERS |
| WO2020092065A1 (en) | 2018-10-29 | 2020-05-07 | Tepha, Inc. | Methods of manufacturing mesh sutures from poly-4-hydroxybutyrate and copolymers thereof |
| US11207445B2 (en) | 2019-07-09 | 2021-12-28 | Community Blood Center | Allograft bone putty and methods of making the same |
| FR3109290B1 (fr) | 2020-04-17 | 2025-04-11 | Ph Tech | Dispositif médical comprenant une matrice biologique acellulaire et au moins un polymère |
| FR3110077B1 (fr) | 2020-05-12 | 2024-12-06 | Ph Tech | Procédé de fabrication d’un dispositif médical en trois dimensions et dispositif médical obtenu |
| US11896736B2 (en) | 2020-07-13 | 2024-02-13 | Globus Medical, Inc | Biomaterial implants and methods of making the same |
| FR3113371A1 (fr) | 2020-08-12 | 2022-02-18 | Ph Tech | Dispositif médical comprenant un assemblage d’éléments de matrices biologiques acellulaires et au moins un polymère |
| CA3213145A1 (en) | 2021-03-11 | 2022-09-15 | Tepha, Inc. | Breast reconstruction implant |
| FR3165166A1 (fr) | 2024-08-05 | 2026-02-06 | Ph Tech | Utilisation de l’Éther de dipropylène glycol monométhylique pour purifier un biomatériau |
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|---|---|---|---|---|
| US4472840A (en) * | 1981-09-21 | 1984-09-25 | Jefferies Steven R | Method of inducing osseous formation by implanting bone graft material |
| US4394370A (en) * | 1981-09-21 | 1983-07-19 | Jefferies Steven R | Bone graft material for osseous defects and method of making same |
| US4722948A (en) * | 1984-03-16 | 1988-02-02 | Dynatech Corporation | Bone replacement and repair putty material from unsaturated polyester resin and vinyl pyrrolidone |
| US6110737A (en) * | 1988-02-02 | 2000-08-29 | The Regents Of The University Of California | Human platelet-derived growth factor receptor, type A |
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| US5693615A (en) * | 1991-06-05 | 1997-12-02 | The Procter & Gamble Company | Therapeutic compositions for osteoinduction |
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| US5817327A (en) * | 1994-07-27 | 1998-10-06 | The Trustees Of The University Of Pennsylvania | Incorporation of biologically active molecules into bioactive glasses |
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| US6030635A (en) | 1998-02-27 | 2000-02-29 | Musculoskeletal Transplant Foundation | Malleable paste for filling bone defects |
-
1997
- 1997-09-02 US US08/922,068 patent/US6309659B1/en not_active Expired - Lifetime
-
1998
- 1998-09-01 AT AT98944660T patent/ATE296642T1/de not_active IP Right Cessation
- 1998-09-01 DE DE69830417T patent/DE69830417T2/de not_active Expired - Lifetime
- 1998-09-01 EP EP05075353A patent/EP1537882A1/de not_active Ceased
- 1998-09-01 WO PCT/US1998/018150 patent/WO1999011298A2/en not_active Ceased
- 1998-09-01 CN CN988140039A patent/CN1292712A/zh active Pending
- 1998-09-01 EP EP98944660A patent/EP1024839B1/de not_active Expired - Lifetime
- 1998-09-01 AU AU92151/98A patent/AU9215198A/en not_active Abandoned
- 1998-09-01 CA CA002302195A patent/CA2302195A1/en not_active Abandoned
-
2001
- 2001-08-27 US US09/939,898 patent/US6623748B2/en not_active Expired - Lifetime
-
2003
- 2003-07-28 US US10/628,147 patent/US20040022858A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| WO1999011298A3 (en) | 1999-06-17 |
| EP1024839A2 (de) | 2000-08-09 |
| AU9215198A (en) | 1999-03-22 |
| CN1292712A (zh) | 2001-04-25 |
| WO1999011298A2 (en) | 1999-03-11 |
| CA2302195A1 (en) | 1999-03-11 |
| US6309659B1 (en) | 2001-10-30 |
| US20020034531A1 (en) | 2002-03-21 |
| US6623748B2 (en) | 2003-09-23 |
| DE69830417D1 (de) | 2005-07-07 |
| US20040022858A1 (en) | 2004-02-05 |
| EP1537882A1 (de) | 2005-06-08 |
| DE69830417T2 (de) | 2006-01-26 |
| EP1024839B1 (de) | 2005-06-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |