ATE296814T1 - Ionenkanal modulierende mittel - Google Patents

Ionenkanal modulierende mittel

Info

Publication number: ATE296814T1
Authority: AT; Austria
Prior art keywords: modulating agents; channel modulating; ion channel; relates; present
Prior art date: 1999-05-12

Application number

AT00926721T

Other languages

English (en)

Inventor

Bo Jensen

Lene Teuber

Palle Christophersen

S Ren Peter Olesen

Original Assignee

Neurosearch As

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1999-05-12

Filing date

2000-05-12

Publication date

2005-06-15

2000-05-12 Application filed by Neurosearch As filed Critical Neurosearch As

2005-06-15 Application granted granted Critical

2005-06-15 Publication of ATE296814T1 publication Critical patent/ATE296814T1/de

Links

102000016469 Large-Conductance Calcium-Activated Potassium Channels Human genes 0.000 abstract 4
108010092555 Large-Conductance Calcium-Activated Potassium Channels Proteins 0.000 abstract 4
239000003795 chemical substances by application Substances 0.000 abstract 4
108091006146 Channels Proteins 0.000 abstract 1
102000004310 Ion Channels Human genes 0.000 abstract 1
108090000862 Ion Channels Proteins 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
201000010099 disease Diseases 0.000 abstract 1
208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
239000003814 drug Substances 0.000 abstract 1
238000004519 manufacturing process Methods 0.000 abstract 1
239000008194 pharmaceutical composition Substances 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
- C07D277/62—Benzothiazoles
- C07D277/68—Benzothiazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
- C07D277/82—Nitrogen atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P21/04—Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis
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- A61P31/14—Antivirals for RNA viruses
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- A—HUMAN NECESSITIES
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- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/52—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems
- C07D263/54—Benzoxazoles; Hydrogenated benzoxazoles
- C07D263/58—Benzoxazoles; Hydrogenated benzoxazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
- C07D277/84—Naphthothiazoles

Landscapes

Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
General Chemical & Material Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Neurosurgery (AREA)
Diabetes (AREA)
Oncology (AREA)
Pulmonology (AREA)
Physical Education & Sports Medicine (AREA)
Urology & Nephrology (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Hematology (AREA)
Pain & Pain Management (AREA)
Psychiatry (AREA)
Endocrinology (AREA)
Immunology (AREA)
Orthopedic Medicine & Surgery (AREA)
Dermatology (AREA)
Communicable Diseases (AREA)
Virology (AREA)
Reproductive Health (AREA)
Rheumatology (AREA)
Molecular Biology (AREA)
Gynecology & Obstetrics (AREA)
Tropical Medicine & Parasitology (AREA)
Obesity (AREA)

AT00926721T 1999-05-12 2000-05-12 Ionenkanal modulierende mittel ATE296814T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DKPA199900657		1999-05-12
PCT/DK2000/000255 WO2000069838A1 (en)	1999-05-12	2000-05-12	Ion channel modulating agents

Publications (1)

Publication Number	Publication Date
ATE296814T1 true ATE296814T1 (de)	2005-06-15

Family

ID=8096053

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT00926721T ATE296814T1 (de)	1999-05-12	2000-05-12	Ionenkanal modulierende mittel

Country Status (7)

Country	Link
US (2)	US20020061914A1 (de)
EP (1)	EP1178977B1 (de)
JP (1)	JP2002544268A (de)
AT (1)	ATE296814T1 (de)
AU (1)	AU4537500A (de)
DE (1)	DE60020556T2 (de)
WO (1)	WO2000069838A1 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DK1539724T3 (da)	2002-08-07	2008-02-11	Neuraxon Inc	Aminobenzothiazolforbindelser med NOS-inhiberende aktivitet
DE10250870A1 (de) *	2002-10-31	2004-05-13	Switch Biotech Ag	Zusammensetzung enthaltend Aktivatoren von IK-Kaliumkanälen und Calcineurin-Antagonisten und deren Verwendung
CA2575882A1 (en) *	2004-08-05	2006-02-09	Neurosearch A/S	2-amino benzimidazole derivatives and their use as modulators of small-conductance calcium-activated potassium channels
EP1838306B1 (de) *	2005-01-11	2010-11-17	NeuroSearch A/S	Neue 2-amino-benzimidazolderivate und ihre verwendung als modulatoren calciumaktivierter kaliumkanäle mit geringer leitfähigkeit
US20070185209A1 (en) *	2005-12-20	2007-08-09	Icagen, Inc.	Treatment methods using triaryl methane compounds
US20100056637A1 (en) *	2005-12-20	2010-03-04	Icagen, Inc.	Treatment methods using triaryl methane compounds
WO2016077541A1 (en) *	2014-11-12	2016-05-19	The Trustees Of The University Of Pennsylvania	Novel anti-infective compounds and methods using same
SG11201707418WA (en)	2015-03-13	2017-10-30	Forma Therapeutics Inc	Alpha-cinnamide compounds and compositions as hdac8 inhibitors
WO2022075780A1 (ko) *	2020-10-07	2022-04-14	광주과학기술원	과민성 방광의 예방 또는 치료용 약학적 조성물

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US2019529A (en) *		1935-11-05		Aminobenzothiazole compound
DE271258C (de)
US1787315A (en) *	1926-04-15	1930-12-30	Ig Farbenindustrie Ag	New compounds of the thiazolic series and process of making same
US2061632A (en) *	1932-07-22	1936-11-24	Du Pont	Safety paper and the like
US2890985A (en) *	1955-08-08	1959-06-16	Sam Joseph	Composition and method for relieving spasticity
US3094462A (en) *	1961-09-18	1963-06-18	Mcneilab Inc	Therapeutic reaction complex for muscle relaxation
DE2631163B2 (de) *	1976-07-10	1978-06-29	Basf Ag, 6700 Ludwigshafen	Verfahren zur Herstellung von 2-Iminobenzothiazolen
US4873346A (en) *	1985-09-20	1989-10-10	The Upjohn Company	Substituted benzothiazoles, benzimidazoles, and benzoxazoles
US4826860A (en) *	1987-03-16	1989-05-02	Warner-Lambert Company	Substituted 2-aminobenzothiazoles and derivatives useful as cerebrovascular agents
FI91859C (fi) *	1987-06-17	1994-08-25	Eisai Co Ltd	Analogiamenetelmä antiallergisena aineena aktiivisen bentsotiatsolijohdannaisen valmistamiseksi
US4808580A (en) *	1987-12-17	1989-02-28	Hoffmann-La Roche Inc.	Naphtho[1,2-b][1,4]thiazepin-4(5H)-ones and use thereof in treatment of ischemia and blood pressure lowering
US4971983A (en) *	1988-12-09	1990-11-20	Warner-Lambert Company	Substituted 2-aminobenzothiazoles and derivatives useful as cerebrovascular agents
US5236940A (en) *	1988-12-15	1993-08-17	Rhone-Poulenc Sante	Pharmaceutical compositions, 2-benzothiazolamine derivatives, and their preparation
FR2649701B2 (fr) *	1988-12-15	1991-11-22	Rhone Poulenc Sante	Derives d'imino-2 benzothiazoline, leurs procedes de preparation et les medicaments les contenant
DE68901859T2 (de) *	1988-12-15	1993-01-14	Rhone Poulenc Sante	2-benzothiazolamin-derivate enthaltende arzneimittel, verbindungen und ihre herstellung.
ZW1992A1 (en) *	1991-02-25	1993-09-22	Janssen Pharmaceutica Nv	4-/(2-benzotiazolyl)methylamino/-b-/(3,4-difluorephenoxy)methyl/-1-piperidine ethanol
FR2684992B1 (fr) *	1991-12-13	1994-02-04	Rhone Poulenc Rorer Sa	Procede de preparation d'amino-2 nitro-7 benzothiazoles.
DE4313930A1 (de) *	1993-04-28	1994-11-03	Hoechst Ag	Verfahren zur Herstellung von 2(3H)-Benzothiazolen
CA2282398A1 (en) *	1997-03-14	1998-09-17	Steven M. Ronkin	Inhibitors of impdh enzyme
AU1117999A (en) *	1997-10-24	1999-05-17	Alliance Pharmaceutical Corporation	Amelioration of ischemic damage using synthetic oxygen carriers

2000
- 2000-05-12 AT AT00926721T patent/ATE296814T1/de not_active IP Right Cessation
- 2000-05-12 EP EP00926721A patent/EP1178977B1/de not_active Expired - Lifetime
- 2000-05-12 DE DE60020556T patent/DE60020556T2/de not_active Expired - Lifetime
- 2000-05-12 WO PCT/DK2000/000255 patent/WO2000069838A1/en not_active Ceased
- 2000-05-12 JP JP2000618255A patent/JP2002544268A/ja active Pending
- 2000-05-12 AU AU45375/00A patent/AU4537500A/en not_active Abandoned
2001
- 2001-11-09 US US09/986,677 patent/US20020061914A1/en not_active Abandoned
2002
- 2002-08-02 US US10/210,043 patent/US6759422B2/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
AU4537500A (en)	2000-12-05
DE60020556T2 (de)	2005-10-27
US6759422B2 (en)	2004-07-06
JP2002544268A (ja)	2002-12-24
EP1178977A1 (de)	2002-02-13
EP1178977B1 (de)	2005-06-01
US20030008906A1 (en)	2003-01-09
DE60020556D1 (de)	2005-07-07
WO2000069838A1 (en)	2000-11-23
US20020061914A1 (en)	2002-05-23

Legal Events

Date	Code	Title	Description
2005-12-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties

Publication	Publication Date	Title
WO2000037422A3 (en)	2000-09-14	Ion channel modulating agents
MY142589A (en)	2010-12-15	Benzimidazole derivatives : preparation and pharmaceutical applications
TW200510375A (en)	2005-03-16	New compounds
BR0215052A (pt)	2004-11-23	Composições acaricidas e métodos
ATE339187T1 (de)	2006-10-15	Verwendung von zusammensetzungen mit antiseptika und/oder die wundheilung fördernden wirkstoffen für den tieferen atemwegstrakt
BR0313676A (pt)	2005-06-21	Derivados de pirimidina e uso destes como moduladores cb2
GT200500137A (es)	2006-05-18	Derivados de pirrolotriazina utiles para tratar trastornos hiper-proliferativos y enfermedades asociadas con angiogenesis.
DE60334773D1 (de)	2010-12-16	Formulierungen zur oralen verabreichung von wirkstoffen
SG10201805552PA (en)	2018-08-30	Sodium channel modulators for the treatment of pain and diabetes
BR0309278A (pt)	2005-04-26	Composto, composição, métodos para modular a atividade da cinesina ksp, para inibir a ksp, para o tratamento de uma doença proliferativa celular, e, uso de um composto
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