ATE296827T1 - Heteropolycyclische inhibitoren - Google Patents

Heteropolycyclische inhibitoren

Info

Publication number
ATE296827T1
ATE296827T1 AT01955500T AT01955500T ATE296827T1 AT E296827 T1 ATE296827 T1 AT E296827T1 AT 01955500 T AT01955500 T AT 01955500T AT 01955500 T AT01955500 T AT 01955500T AT E296827 T1 ATE296827 T1 AT E296827T1
Authority
AT
Austria
Prior art keywords
heteropolycyclic
inhibitors
administering
compound
formula
Prior art date
Application number
AT01955500T
Other languages
English (en)
Inventor
Zaihui Zhang
Xinyao Du
Greg Chopiuk
Serguei Sviridov
Original Assignee
Quadra Logic Tech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Quadra Logic Tech Inc filed Critical Quadra Logic Tech Inc
Application granted granted Critical
Publication of ATE296827T1 publication Critical patent/ATE296827T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT01955500T 2000-07-06 2001-07-06 Heteropolycyclische inhibitoren ATE296827T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US61103800A 2000-07-06 2000-07-06
PCT/IB2001/001519 WO2002002562A2 (en) 2000-07-06 2001-07-06 Heteropolycyclic inhibitors

Publications (1)

Publication Number Publication Date
ATE296827T1 true ATE296827T1 (de) 2005-06-15

Family

ID=24447360

Family Applications (1)

Application Number Title Priority Date Filing Date
AT01955500T ATE296827T1 (de) 2000-07-06 2001-07-06 Heteropolycyclische inhibitoren

Country Status (8)

Country Link
US (2) US6514972B2 (de)
EP (1) EP1296985B1 (de)
AT (1) ATE296827T1 (de)
AU (1) AU2001277659A1 (de)
CA (1) CA2414885A1 (de)
DE (1) DE60111228T2 (de)
ES (1) ES2243527T3 (de)
WO (1) WO2002002562A2 (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002002562A2 (en) * 2000-07-06 2002-01-10 Kinetek Pharmaceuticals, Inc. Heteropolycyclic inhibitors
US8715708B2 (en) * 2005-08-31 2014-05-06 University Of Maryland Cyclic acetal biomaterials
EP1798232A1 (de) * 2005-12-08 2007-06-20 Hybrigenics S.A. Cysteine Proteasehemmer, deren pharmazeutische Zusammensetzungen und therapeutische Anwendungen
ES2439456T3 (es) * 2005-12-08 2014-01-23 Hybrigenics S.A. Inhibidores de cisteína proteasas, las composiciones farmacéuticas de las mismas y sus aplicaciones terapéuticas
US7462615B2 (en) * 2005-12-08 2008-12-09 Hybrigenics Sa Inhibitors of cysteine proteases, the pharmaceutical compositions thereof and their therapeutic applications
US7875613B2 (en) * 2006-10-30 2011-01-25 Hybrigenics Sa Tetracyclic inhibitors of cysteine proteases, the pharmaceutical compositions thereof and their therapeutic applications
EP1918292A1 (de) * 2006-10-30 2008-05-07 Hybrigenics S.A. Tetrazyklische Inhibitoren für Cysteinproteasen, pharmazeutische Zubereitungen und therapeutische Anwendungen
AU2007315885B2 (en) * 2006-10-30 2013-01-31 Hybrigenics Sa Novel tetracyclic inhibitors of cysteine proteases, the pharmaceutical compositions thereof and their therapeutic applications
WO2012006104A2 (en) * 2010-06-28 2012-01-12 Academia Sinica, Taiwan Compounds and methods for treating tuberculosis infection
CN103520165A (zh) * 2013-10-31 2014-01-22 华东理工大学 茚并三嗪类化合物作为依赖nad(p)h的醌氧化还原酶底物的用途
CN107530328A (zh) 2015-05-15 2018-01-02 印第安纳大学研究与技术公司 靶向存活蛋白的抗肿瘤剂及其用途
CN105061360B (zh) * 2015-07-28 2018-06-19 首都师范大学 一种3,4-二氨基-1,2,5-噻二唑的提纯方法
CA3114166A1 (en) * 2018-09-28 2020-04-02 Acucela Inc. Inhibitors of vap-1
CN113164454A (zh) 2018-09-28 2021-07-23 奥克塞拉有限公司 Vap-1的抑制剂
US20210283064A1 (en) * 2020-02-25 2021-09-16 The Chinese University Of Hong Kong Stable, bioadhesive, and diffusion-restrictive coacervate
US12128050B2 (en) 2020-11-10 2024-10-29 New Mexico Tech University Research Park Corporation KP372-1-induced DNA damage as a chemotherapeutic approach to treat cancer

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4159375A (en) * 1978-08-24 1979-06-26 American Cyanamid Company 6- AND 7-Aryl-1,2,4-triazolo[4,3-b]-1,2,4-triazines
US4405619A (en) * 1981-09-02 1983-09-20 Diamond Shamrock Corporation Antiinflammatory substituted-1,2,4-triazolo[4,3-b]-1,2,4-triazines
GB8826237D0 (en) 1988-11-09 1988-12-14 Univ Belfast Fingerprint reagent
AU2096895A (en) 1994-03-07 1995-09-25 Sugen, Incorporated Receptor tyrosine kinase inhibitors for inhibiting cell proliferative disorders and compositions thereof
WO2001079209A2 (en) * 2000-04-13 2001-10-25 Millennium Pharmaceuticals, Inc. Diazafluorenone il-8 antagonists
WO2002002562A2 (en) * 2000-07-06 2002-01-10 Kinetek Pharmaceuticals, Inc. Heteropolycyclic inhibitors

Also Published As

Publication number Publication date
EP1296985A2 (de) 2003-04-02
WO2002002562A3 (en) 2002-05-02
US7196083B2 (en) 2007-03-27
US20020035251A1 (en) 2002-03-21
CA2414885A1 (en) 2002-01-10
DE60111228T2 (de) 2006-03-16
AU2001277659A1 (en) 2002-01-14
US6514972B2 (en) 2003-02-04
DE60111228D1 (de) 2005-07-07
WO2002002562A2 (en) 2002-01-10
EP1296985B1 (de) 2005-06-01
ES2243527T3 (es) 2005-12-01
US20030144294A1 (en) 2003-07-31

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