ATE297224T1 - Auf stimuli reagierendes gel enthaltend ein radioisotop und verfahren zur herstellung - Google Patents
Auf stimuli reagierendes gel enthaltend ein radioisotop und verfahren zur herstellungInfo
- Publication number
- ATE297224T1 ATE297224T1 AT99938691T AT99938691T ATE297224T1 AT E297224 T1 ATE297224 T1 AT E297224T1 AT 99938691 T AT99938691 T AT 99938691T AT 99938691 T AT99938691 T AT 99938691T AT E297224 T1 ATE297224 T1 AT E297224T1
- Authority
- AT
- Austria
- Prior art keywords
- gelling
- stimulus
- copolymer
- sensitive
- radioisotope
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/06—Macromolecular compounds, carriers being organic macromolecular compounds, i.e. organic oligomeric, polymeric, dendrimeric molecules
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/12—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules
- A61K51/1213—Semi-solid forms, gels, hydrogels, ointments, fats and waxes that are solid at room temperature
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Optics & Photonics (AREA)
- Physics & Mathematics (AREA)
- Epidemiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Dispersion Chemistry (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Manufacture Of Macromolecular Shaped Articles (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/058,712 US6296831B1 (en) | 1998-04-10 | 1998-04-10 | Stimulus sensitive gel with radioisotope and methods of making |
| PCT/US1999/007662 WO1999055386A2 (en) | 1998-04-10 | 1999-04-06 | Stimulus sensitive gel with radioisotope and methods of making |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE297224T1 true ATE297224T1 (de) | 2005-06-15 |
Family
ID=22018452
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT99938691T ATE297224T1 (de) | 1998-04-10 | 1999-04-06 | Auf stimuli reagierendes gel enthaltend ein radioisotop und verfahren zur herstellung |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US6296831B1 (de) |
| EP (1) | EP1069919B1 (de) |
| JP (1) | JP2002512987A (de) |
| AT (1) | ATE297224T1 (de) |
| AU (1) | AU752477B2 (de) |
| CA (1) | CA2327325C (de) |
| DE (1) | DE69925722T2 (de) |
| NZ (1) | NZ507174A (de) |
| WO (1) | WO1999055386A2 (de) |
Families Citing this family (64)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0986402A2 (de) * | 1997-06-06 | 2000-03-22 | Battelle Memorial Institute | Reversibles gelbindendes copolymer und verfahren |
| US20040228794A1 (en) * | 1998-04-10 | 2004-11-18 | Battelle Memorial Institute | Therapeutic agent carrier compositions |
| US7087244B2 (en) | 2000-09-28 | 2006-08-08 | Battelle Memorial Institute | Thermogelling oligopeptide polymers |
| US6296831B1 (en) * | 1998-04-10 | 2001-10-02 | Battelle Memorial Institute | Stimulus sensitive gel with radioisotope and methods of making |
| US20030176663A1 (en) * | 1998-05-11 | 2003-09-18 | Eidgenossische Technische Hochscule | Specific binding molecules for scintigraphy |
| GB9905048D0 (en) * | 1999-03-05 | 1999-04-28 | Reckitt & Colmann Prod Ltd | Improvements in or relating to organic compositions |
| DE19953636A1 (de) * | 1999-11-09 | 2001-05-23 | Karlsruhe Forschzent | Radioaktive Materialien |
| JP2003524018A (ja) * | 2000-02-24 | 2003-08-12 | アイトゲネーシシェ テクニシェ ホッホシューレ チューリッヒ | フィブロネクチンのed‐bドメインに特異的な抗体、前記抗体を含む複合体、および血管形成を検出および治療するためのその使用 |
| US6660247B1 (en) * | 2000-06-23 | 2003-12-09 | Battelle Memorial Institute | Multiple stimulus reversible hydrogels |
| CN1246333C (zh) * | 2000-09-07 | 2006-03-22 | 舍林股份公司 | EDb-纤粘连蛋白结构域(II)的受体 |
| AU2002228955B2 (en) * | 2000-12-20 | 2005-09-29 | Alcon Inc. | Solution for removing cataracts via liquefracture |
| AU2001248807B2 (en) * | 2001-04-20 | 2007-08-09 | Kohjin Co., Ltd. | Fire-Extinguishing Agent, Water for Fire Extinguishing, and Method of Fire Extinguishing |
| FR2824832B1 (fr) * | 2001-05-16 | 2005-05-27 | Oreal | Polymeres hydrosolubles a squelette hydrosoluble et a unites laterales a lcst, leur procede de preparation, compositions aqueuses les contenant, et leur utilisation dans le domaine cosmetique |
| WO2003105762A2 (en) * | 2002-06-14 | 2003-12-24 | Actinium Pharmaceuticals Ltd. | Treating disease using radium-225 |
| JP5346148B2 (ja) * | 2003-03-28 | 2013-11-20 | エー・デー・ガイストリヒ・ゾーネ・アクチェンゲゼルシャフト・フュール・ヒェーミシェ・インダストリー | 抗新生物性組成物および治療方法 |
| US20040220135A1 (en) * | 2003-04-30 | 2004-11-04 | Sirtex Medical Limited | Combination therapy for treatment of neoplasia |
| US7273445B2 (en) * | 2003-04-30 | 2007-09-25 | Board Of Trustees Of The University Of Illinois | Intraocular brachytherapy device and method |
| WO2006078320A2 (en) * | 2004-08-04 | 2006-07-27 | Brookwood Pharmaceuticals, Inc. | Methods for manufacturing delivery devices and devices thereof |
| AU2005290229A1 (en) * | 2004-09-24 | 2006-04-06 | Biosphere Medical, Inc. | Microspheres capable of binding radioisotopes, optionally comprising metallic microparticles, and methods of use thereof |
| CA2615589A1 (en) * | 2005-07-26 | 2007-02-01 | Ramot At Tel Aviv University Ltd. | A radioactive surface source and a method for producing the same |
| US20080038190A1 (en) * | 2006-08-11 | 2008-02-14 | Simpson Thomas J | Composition apparatus and method for use in imaging |
| US20100040667A1 (en) * | 2006-09-07 | 2010-02-18 | Ed. Geistlich Soehne Ag Fuer Chemische Industrie | Method of treating bone cancer |
| EP1985286A1 (de) * | 2007-04-24 | 2008-10-29 | Biocompatibles UK Limited | Mikrokügelchen zur Behandlung von Gehirntumoren |
| US8480651B2 (en) * | 2007-08-02 | 2013-07-09 | Covidien Lp | Cannula system |
| WO2009085952A1 (en) | 2007-12-20 | 2009-07-09 | Brookwood Pharmaceuticals, Inc. | Process for preparing microparticles having a low residual solvent volume |
| US8253725B2 (en) * | 2007-12-28 | 2012-08-28 | St. Jude Medical, Atrial Fibrillation Division, Inc. | Method and system for generating surface models of geometric structures |
| US8608632B1 (en) | 2009-07-03 | 2013-12-17 | Salutaris Medical Devices, Inc. | Methods and devices for minimally-invasive extraocular delivery of radiation and/or pharmaceutics to the posterior portion of the eye |
| DK2227257T3 (da) | 2008-01-07 | 2013-09-30 | Salutaris Medical Devices Inc | Anordninger til minimal-invasiv ekstraokular afgivelse af stråling til den posteriore del af øjet |
| US8821364B2 (en) | 2008-09-02 | 2014-09-02 | Battelle Memorial Institute | Brachytherapy seed with fast dissolving matrix for optimal delivery of radionuclides to cancer tissue |
| FR2939666B1 (fr) * | 2008-12-17 | 2012-11-30 | Irsn | Formulations cosmetiques et pharmaceutiques de molecules de calix[6]arenes |
| US8663210B2 (en) * | 2009-05-13 | 2014-03-04 | Novian Health, Inc. | Methods and apparatus for performing interstitial laser therapy and interstitial brachytherapy |
| JP2013505251A (ja) * | 2009-09-17 | 2013-02-14 | エボニック デグサ コーポレイション | 放出プロファイルが異なるインプラントデバイス並びにその製造及び使用方法 |
| KR20120107070A (ko) * | 2009-09-22 | 2012-09-28 | 에보닉 데구사 코포레이션 | 다양한 생리활성 물질 로딩 구성을 갖는 임플란트 장치 |
| WO2013176522A1 (ko) * | 2012-05-24 | 2013-11-28 | 서강대학교산학협력단 | 카트리지를 이용한 방사성의약품 제조방법 |
| NL2009688C2 (en) * | 2012-10-24 | 2014-04-29 | Nucletron Operations Bv | A settable radioactive gel, a method of manufacturing a settable radioactive gel, a device for manufacturing a settable radioactive gel. |
| WO2014159759A1 (en) | 2013-03-13 | 2014-10-02 | Biosphere Medical, Inc. | Compositions and associated methods for radioisotope-binding microparticles |
| US9899133B2 (en) | 2013-08-01 | 2018-02-20 | Qorvo Us, Inc. | Advanced 3D inductor structures with confined magnetic field |
| US10364451B2 (en) | 2013-05-30 | 2019-07-30 | Duke University | Polymer conjugates having reduced antigenicity and methods of using the same |
| US10392611B2 (en) | 2013-05-30 | 2019-08-27 | Duke University | Polymer conjugates having reduced antigenicity and methods of using the same |
| CN103736201B (zh) * | 2013-12-31 | 2016-01-20 | 原子高科股份有限公司 | 一种放射性粒子链 |
| KR102317751B1 (ko) | 2014-01-24 | 2021-10-27 | 서텍스 메디컬 피티와이 엘티디 | 신생물의 치료 |
| CN104147688A (zh) * | 2014-07-31 | 2014-11-19 | 吉林大学 | 一种快速成型自适应近距离后装施源器及其制作方法 |
| US10385115B2 (en) | 2015-03-26 | 2019-08-20 | Duke University | Fibronectin type III domain-based fusion proteins |
| EA037478B1 (ru) | 2015-08-04 | 2021-04-01 | Дьюк Юниверсити | Генетически кодируемые внутренне неупорядоченные полимеры-"невидимки" для доставки и способы их применения |
| US11752213B2 (en) | 2015-12-21 | 2023-09-12 | Duke University | Surfaces having reduced non-specific binding and antigenicity |
| WO2017210476A1 (en) | 2016-06-01 | 2017-12-07 | Duke University | Nonfouling biosensors |
| WO2018053201A1 (en) | 2016-09-14 | 2018-03-22 | Duke University | Triblock polypeptide-based nanoparticles for the delivery of hydrophilic drugs |
| JP2020500150A (ja) | 2016-09-23 | 2020-01-09 | デューク ユニバーシティ | 下限臨界溶液温度挙動を有する非反復かつ非構造的ポリペプチド |
| US11963839B2 (en) | 2017-01-10 | 2024-04-23 | A. T. Still University | Dental monitoring system |
| WO2018132732A1 (en) | 2017-01-12 | 2018-07-19 | Duke University | Genetically encoded lipid-polypeptide hybrid biomaterials that exhibit temperature triggered hierarchical self-assembly |
| US20190380951A1 (en) * | 2017-01-24 | 2019-12-19 | ScintHealth GmbH | Composition, device and method for conformational intra-tissue beta brachytherapy |
| WO2018213320A1 (en) | 2017-05-15 | 2018-11-22 | Duke University | Recombinant production of hybrid lipid-biopolymer materials that self-assemble and encapsulate agents |
| WO2019006374A1 (en) | 2017-06-30 | 2019-01-03 | Duke University | ORDER AND DISORDER AS A DESIGN PRINCIPLE FOR STIMULI-SENSITIVE BIOPOLYMER NETWORKS |
| WO2019147954A1 (en) | 2018-01-26 | 2019-08-01 | Duke University | Albumin binding peptide-drug (aibiped) conjugates and methods of making and using same |
| EP3788343B1 (de) | 2018-04-30 | 2024-03-27 | Duke University | Auf stimuli reagierende plattform zur abgabe von auf peg-like-polymer basierendem arzneimittel |
| US11649275B2 (en) | 2018-08-02 | 2023-05-16 | Duke University | Dual agonist fusion proteins |
| US12594347B2 (en) | 2018-09-07 | 2026-04-07 | Duke University | Nanoparticulate drug delivery systems |
| BR112021007969A2 (pt) | 2018-10-29 | 2021-07-27 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | complexos de tetraciclina com atividade controlada |
| CN114364405B (zh) * | 2019-04-26 | 2024-07-16 | 五一一制药股份有限公司 | 作为诊断剂和放射性核素治疗剂的前列腺特异性膜抗原(psma)抑制剂 |
| US12521452B2 (en) | 2019-07-01 | 2026-01-13 | Vivos, Inc. | Radiotherapy gel and method of preparing the same |
| US12491269B2 (en) | 2019-07-01 | 2025-12-09 | Vivos, Inc. | Radioactive yttrium phosphate suspension and method of preparing the same |
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| US11512314B2 (en) | 2019-07-12 | 2022-11-29 | Duke University | Amphiphilic polynucleotides |
| CN120590625A (zh) * | 2024-11-06 | 2025-09-05 | 江苏申命医疗科技有限公司 | 一种放射性核素标记的聚合物、其制备方法及应用 |
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| CA980022A (en) | 1972-05-15 | 1975-12-16 | Douglas Whitfield | Remotely controlled brachytherapy unit |
| US4190461A (en) | 1978-03-20 | 1980-02-26 | Alpha-Omega Services, Inc. | Method for removing metallic seeds from nylon tubing used in interstitial brachytherapy |
| US4510924A (en) | 1980-07-10 | 1985-04-16 | Yale-New Haven Hospital, Inc. | Brachytherapy devices and methods employing americium-241 |
| US4754745A (en) | 1984-11-21 | 1988-07-05 | Horowitz Bruce S | Conformable sheet material for use in brachytherapy |
| US5322499A (en) | 1985-09-20 | 1994-06-21 | Liprie Sam F | Continuous sheated low dose radioactive core adapted for cutting into short sealed segments |
| US4763642A (en) | 1986-04-07 | 1988-08-16 | Horowitz Bruce S | Intracavitational brachytherapy |
| US4763462A (en) * | 1986-10-24 | 1988-08-16 | Wayne Automation Corp. | Method for inserting partitions |
| USH669H (en) * | 1986-12-08 | 1989-09-05 | The United States Of America As Represented By The United States Department Of Energy | Samarium-145 and its use as a radiation source |
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| US5262055A (en) | 1992-10-19 | 1993-11-16 | The University Of Utah | Implantable and refillable biohybrid artificial pancreas |
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| EP0986402A2 (de) | 1997-06-06 | 2000-03-22 | Battelle Memorial Institute | Reversibles gelbindendes copolymer und verfahren |
| US6015541A (en) | 1997-11-03 | 2000-01-18 | Micro Therapeutics, Inc. | Radioactive embolizing compositions |
| US6296831B1 (en) * | 1998-04-10 | 2001-10-02 | Battelle Memorial Institute | Stimulus sensitive gel with radioisotope and methods of making |
| US6296837B1 (en) * | 2000-03-14 | 2001-10-02 | Ting-Chun Tsai | Fragrant fingernail polish |
-
1998
- 1998-04-10 US US09/058,712 patent/US6296831B1/en not_active Expired - Lifetime
-
1999
- 1999-04-06 WO PCT/US1999/007662 patent/WO1999055386A2/en not_active Ceased
- 1999-04-06 JP JP2000545582A patent/JP2002512987A/ja active Pending
- 1999-04-06 AT AT99938691T patent/ATE297224T1/de not_active IP Right Cessation
- 1999-04-06 CA CA002327325A patent/CA2327325C/en not_active Expired - Lifetime
- 1999-04-06 NZ NZ507174A patent/NZ507174A/en unknown
- 1999-04-06 DE DE69925722T patent/DE69925722T2/de not_active Expired - Fee Related
- 1999-04-06 EP EP99938691A patent/EP1069919B1/de not_active Expired - Lifetime
- 1999-04-06 AU AU53118/99A patent/AU752477B2/en not_active Ceased
-
2001
- 2001-05-09 US US09/853,507 patent/US6869588B2/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| EP1069919A2 (de) | 2001-01-24 |
| DE69925722T2 (de) | 2005-12-15 |
| NZ507174A (en) | 2003-11-28 |
| US6869588B2 (en) | 2005-03-22 |
| US6296831B1 (en) | 2001-10-02 |
| CA2327325A1 (en) | 1999-11-04 |
| JP2002512987A (ja) | 2002-05-08 |
| WO1999055386A3 (en) | 2000-06-29 |
| AU752477B2 (en) | 2002-09-19 |
| DE69925722D1 (de) | 2005-07-14 |
| WO1999055386A2 (en) | 1999-11-04 |
| AU5311899A (en) | 1999-11-16 |
| EP1069919B1 (de) | 2005-06-08 |
| US20010024636A1 (en) | 2001-09-27 |
| CA2327325C (en) | 2006-01-24 |
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