ATE527000T1 - Bioabbaubares polymersystem - Google Patents

Bioabbaubares polymersystem

Info

Publication number
ATE527000T1
ATE527000T1 AT02735663T AT02735663T ATE527000T1 AT E527000 T1 ATE527000 T1 AT E527000T1 AT 02735663 T AT02735663 T AT 02735663T AT 02735663 T AT02735663 T AT 02735663T AT E527000 T1 ATE527000 T1 AT E527000T1
Authority
AT
Austria
Prior art keywords
biodegradable polymer
polymer system
anhydride
inclusion
degradation
Prior art date
Application number
AT02735663T
Other languages
English (en)
Inventor
John Rose
Steven Hardwick
Original Assignee
Smith & Nephew
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smith & Nephew filed Critical Smith & Nephew
Application granted granted Critical
Publication of ATE527000T1 publication Critical patent/ATE527000T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/58—Materials at least partially resorbable by the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L17/00—Materials for surgical sutures or for ligaturing blood vessels ; Materials for prostheses or catheters
    • A61L17/06—At least partially resorbable materials
    • A61L17/10—At least partially resorbable materials containing macromolecular materials
    • A61L17/12—Homopolymers or copolymers of glycolic acid or lactic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/26—Mixtures of macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/40—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
    • A61L27/44—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B17/04—Surgical instruments, devices or methods for suturing wounds; Holders or packages for needles or suture materials
    • A61B17/0401—Suture anchors, buttons or pledgets, i.e. means for attaching sutures to bone, cartilage or soft tissue; Instruments for applying or removing suture anchors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B17/04—Surgical instruments, devices or methods for suturing wounds; Holders or packages for needles or suture materials
    • A61B17/06—Needles ; Sutures; Needle-suture combinations; Holders or packages for needles or suture materials
    • A61B17/06166—Sutures
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B17/56—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
    • A61B17/58—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws or setting implements
    • A61B17/68—Internal fixation devices, including fasteners and spinal fixators, even if a part thereof projects from the skin
    • A61B17/72—Intramedullary devices, e.g. pins or nails
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B17/56—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
    • A61B17/58—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws or setting implements
    • A61B17/68—Internal fixation devices, including fasteners and spinal fixators, even if a part thereof projects from the skin
    • A61B17/80—Cortical plates, i.e. bone plates; Instruments for holding or positioning cortical plates, or for compressing bones attached to cortical plates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B17/56—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
    • A61B17/58—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws or setting implements
    • A61B17/68—Internal fixation devices, including fasteners and spinal fixators, even if a part thereof projects from the skin
    • A61B17/80—Cortical plates, i.e. bone plates; Instruments for holding or positioning cortical plates, or for compressing bones attached to cortical plates
    • A61B17/8061—Cortical plates, i.e. bone plates; Instruments for holding or positioning cortical plates, or for compressing bones attached to cortical plates specially adapted for particular bones
    • A61B17/8071—Cortical plates, i.e. bone plates; Instruments for holding or positioning cortical plates, or for compressing bones attached to cortical plates specially adapted for particular bones for the jaw
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B17/56—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
    • A61B17/58—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws or setting implements
    • A61B17/68—Internal fixation devices, including fasteners and spinal fixators, even if a part thereof projects from the skin
    • A61B17/84—Fasteners therefor or fasteners being internal fixation devices
    • A61B17/86—Pins or screws or threaded wires; nuts therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B17/56—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
    • A61B17/58—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws or setting implements
    • A61B17/68—Internal fixation devices, including fasteners and spinal fixators, even if a part thereof projects from the skin
    • A61B17/84—Fasteners therefor or fasteners being internal fixation devices
    • A61B17/86—Pins or screws or threaded wires; nuts therefor
    • A61B17/866—Material or manufacture
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B2017/00004—(bio)absorbable, (bio)resorbable or resorptive
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2250/00—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2250/0014—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof having different values of a given property or geometrical feature, e.g. mechanical property or material property, at different locations within the same prosthesis
    • A61F2250/003—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof having different values of a given property or geometrical feature, e.g. mechanical property or material property, at different locations within the same prosthesis differing in adsorbability or resorbability, i.e. in adsorption or resorption time

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Transplantation (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Medicinal Chemistry (AREA)
  • Dermatology (AREA)
  • Engineering & Computer Science (AREA)
  • Materials Engineering (AREA)
  • Surgery (AREA)
  • Vascular Medicine (AREA)
  • Composite Materials (AREA)
  • Materials For Medical Uses (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Biological Depolymerization Polymers (AREA)
AT02735663T 2001-07-04 2002-07-03 Bioabbaubares polymersystem ATE527000T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0116341.9A GB0116341D0 (en) 2001-07-04 2001-07-04 Biodegradable polymer systems
PCT/GB2002/003072 WO2003004071A1 (en) 2001-07-04 2002-07-03 Biodegradable polymer systems

Publications (1)

Publication Number Publication Date
ATE527000T1 true ATE527000T1 (de) 2011-10-15

Family

ID=9917916

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02735663T ATE527000T1 (de) 2001-07-04 2002-07-03 Bioabbaubares polymersystem

Country Status (9)

Country Link
US (1) US7524891B2 (de)
EP (1) EP1401510B1 (de)
JP (1) JP2004533308A (de)
AT (1) ATE527000T1 (de)
AU (1) AU2002310552B2 (de)
CA (1) CA2452358C (de)
ES (1) ES2374555T3 (de)
GB (1) GB0116341D0 (de)
WO (1) WO2003004071A1 (de)

Families Citing this family (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0116341D0 (en) 2001-07-04 2001-08-29 Smith & Nephew Biodegradable polymer systems
GB0202233D0 (en) 2002-01-31 2002-03-20 Smith & Nephew Bioresorbable polymers
GB0317192D0 (en) * 2003-07-19 2003-08-27 Smith & Nephew High strength bioresorbable co-polymers
GB0329654D0 (en) 2003-12-23 2004-01-28 Smith & Nephew Tunable segmented polyacetal
JP2009504929A (ja) * 2005-08-18 2009-02-05 スミス アンド ネフュー ピーエルシー 高強度デバイス及び複合材料
JP2009511092A (ja) * 2005-08-18 2009-03-19 スミス アンド ネフュー ピーエルシー マルチモーダル高強度デバイス及び複合材料
WO2007103276A2 (en) 2006-03-03 2007-09-13 Smith & Nephew, Inc. Systems and methods for delivering a medicament
US7794495B2 (en) * 2006-07-17 2010-09-14 Advanced Cardiovascular Systems, Inc. Controlled degradation of stents
US8394488B2 (en) * 2006-10-06 2013-03-12 Cordis Corporation Bioabsorbable device having composite structure for accelerating degradation
US8828419B2 (en) * 2006-10-06 2014-09-09 Cordis Corporation Bioabsorbable device having encapsulated additives for accelerating degradation
US20080177330A1 (en) * 2006-10-24 2008-07-24 Ralph James D Self-locking screws for medical implants
US20080103584A1 (en) * 2006-10-25 2008-05-01 Biosensors International Group Temporal Intraluminal Stent, Methods of Making and Using
US8722783B2 (en) * 2006-11-30 2014-05-13 Smith & Nephew, Inc. Fiber reinforced composite material
EP2142353A1 (de) 2007-04-18 2010-01-13 Smith & Nephew PLC Expansionsformen von formgedächtnis-polymeren
JP5520814B2 (ja) 2007-04-19 2014-06-11 スミス アンド ネフュー インコーポレーテッド マルチモーダル形状記憶ポリマー
WO2008130954A2 (en) 2007-04-19 2008-10-30 Smith & Nephew, Inc. Graft fixation
EP2142228A1 (de) * 2007-04-19 2010-01-13 Smith & Nephew, Inc. Formgedächtnis-polymere mit mittel zur beschleunigung des abbaus
GB0715376D0 (en) * 2007-08-07 2007-09-19 Smith & Nephew Coating
GB0813659D0 (en) 2008-07-25 2008-09-03 Smith & Nephew Fracture putty
GB0819296D0 (en) * 2008-10-21 2008-11-26 Smith & Nephew Coating II
US8506608B2 (en) 2009-03-24 2013-08-13 Douglas Cerynik Orthopedic fixation device with bioresorbable layer
US8889823B2 (en) * 2009-07-21 2014-11-18 Abbott Cardiovascular Systems Inc. Method to make poly(L-lactide) stent with tunable degradation rate
US9889238B2 (en) * 2009-07-21 2018-02-13 Abbott Cardiovascular Systems Inc. Biodegradable stent with adjustable degradation rate
US8506593B2 (en) 2010-04-11 2013-08-13 Lap IP, Inc Implantable biodegradable wound closure device and method
US20120009420A1 (en) 2010-07-07 2012-01-12 Lifoam Industries Compostable or Biobased Foams
US8962706B2 (en) 2010-09-10 2015-02-24 Lifoam Industries, Llc Process for enabling secondary expansion of expandable beads
US10525168B2 (en) 2010-10-20 2020-01-07 206 Ortho, Inc. Method and apparatus for treating bone fractures, and/or for fortifying and/or augmenting bone, including the provision and use of composite implants, and novel composite structures which may be used for medical and non-medical applications
US11207109B2 (en) 2010-10-20 2021-12-28 206 Ortho, Inc. Method and apparatus for treating bone fractures, and/or for fortifying and/or augmenting bone, including the provision and use of composite implants, and novel composite structures which may be used for medical and non-medical applications
US20120101593A1 (en) 2010-10-20 2012-04-26 BIOS2 Medical, Inc. Implantable polymer for bone and vascular lesions
US11291483B2 (en) 2010-10-20 2022-04-05 206 Ortho, Inc. Method and apparatus for treating bone fractures, and/or for fortifying and/or augmenting bone, including the provision and use of composite implants
US10525169B2 (en) 2010-10-20 2020-01-07 206 Ortho, Inc. Method and apparatus for treating bone fractures, and/or for fortifying and/or augmenting bone, including the provision and use of composite implants, and novel composite structures which may be used for medical and non-medical applications
US11058796B2 (en) 2010-10-20 2021-07-13 206 Ortho, Inc. Method and apparatus for treating bone fractures, and/or for fortifying and/or augmenting bone, including the provision and use of composite implants, and novel composite structures which may be used for medical and non-medical applications
US11484627B2 (en) 2010-10-20 2022-11-01 206 Ortho, Inc. Method and apparatus for treating bone fractures, and/or for fortifying and/or augmenting bone, including the provision and use of composite implants, and novel composite structures which may be used for medical and non-medical applications
CN102093540A (zh) * 2010-11-18 2011-06-15 江南大学 一种蓖麻油酸基弹性体
CN102030889A (zh) * 2010-11-18 2011-04-27 江南大学 一种光响应型聚酯
US8834776B2 (en) 2011-05-10 2014-09-16 Abbott Cardiovascular Systems Inc. Control of degradation profile of bioabsorbable poly(l-lactide) scaffold
EP2819620A4 (de) 2012-02-29 2015-11-04 206 Ortho Inc Verfahren und vorrichtung zur behandlung von knochenbrüchen unter verwendung von zusammengesetzten implantaten
US10675376B2 (en) 2012-05-24 2020-06-09 Ethicon Llc Mechanically strong absorbable polymeric blend compositions of precisely controllable absorption rates, processing methods, and products therefrom
CA2898412C (en) * 2013-01-18 2016-09-06 Kureha Corporation Well treatment fluid material and well treatment fluid comprising the same
EP2999747B1 (de) 2013-05-23 2020-08-12 206 ORTHO, Inc. Vorrichtung zur behandlung von knochenbrüchen und/oder zur stärkung und/oder vermehrung von knochen
KR20160091960A (ko) 2013-11-27 2016-08-03 에티컨, 엘엘씨 정밀하게 제어가능한 흡수 속도를 갖는 흡수성 중합체 블렌드 조성물, 가공 방법, 및 그로부터의 치수 안정한 의료 장치

Family Cites Families (191)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL216498A (de) 1955-11-30
US3531561A (en) * 1965-04-20 1970-09-29 Ethicon Inc Suture preparation
US3797499A (en) * 1970-05-13 1974-03-19 Ethicon Inc Polylactide fabric graphs for surgical implantation
BE758156R (fr) * 1970-05-13 1971-04-28 Ethicon Inc Element de suture absorbable et sa
US3736646A (en) * 1971-10-18 1973-06-05 American Cyanamid Co Method of attaching surgical needles to multifilament polyglycolic acid absorbable sutures
US4137921A (en) * 1977-06-24 1979-02-06 Ethicon, Inc. Addition copolymers of lactide and glycolide and method of preparation
US4181983A (en) * 1977-08-29 1980-01-08 Kulkarni R K Assimilable hydrophilic prosthesis
US5110852A (en) * 1982-07-16 1992-05-05 Rijksuniversiteit Te Groningen Filament material polylactide mixtures
US4700704A (en) 1982-10-01 1987-10-20 Ethicon, Inc. Surgical articles of copolymers of glycolide and ε-caprolactone and methods of producing the same
US4523591A (en) * 1982-10-22 1985-06-18 Kaplan Donald S Polymers for injection molding of absorbable surgical devices
US4539981A (en) * 1982-11-08 1985-09-10 Johnson & Johnson Products, Inc. Absorbable bone fixation device
US4438253A (en) * 1982-11-12 1984-03-20 American Cyanamid Company Poly(glycolic acid)/poly(alkylene glycol) block copolymers and method of manufacturing the same
US4643734A (en) 1983-05-05 1987-02-17 Hexcel Corporation Lactide/caprolactone polymer, method of making the same, composites thereof, and prostheses produced therefrom
US4636215A (en) * 1984-01-11 1987-01-13 Rei, Inc. Combination tray and condylar prosthesis for mandibular reconstruction and the like
US4990161A (en) * 1984-03-16 1991-02-05 Kampner Stanley L Implant with resorbable stem
US4840632A (en) * 1984-03-16 1989-06-20 Kampner Stanley L Hip prosthesis
US4559945A (en) 1984-09-21 1985-12-24 Ethicon, Inc. Absorbable crystalline alkylene malonate copolyesters and surgical devices therefrom
FI75493C (fi) 1985-05-08 1988-07-11 Materials Consultants Oy Sjaelvarmerat absorberbart osteosyntesmedel.
US4776329A (en) 1985-09-20 1988-10-11 Richards Medical Company Resorbable compressing screw and method
US6005161A (en) 1986-01-28 1999-12-21 Thm Biomedical, Inc. Method and device for reconstruction of articular cartilage
FI81498C (fi) 1987-01-13 1990-11-12 Biocon Oy Kirurgiska material och instrument.
US5527337A (en) * 1987-06-25 1996-06-18 Duke University Bioabsorbable stent and method of making the same
DE8716607U1 (de) 1987-12-14 1989-01-12 Mecron Medizinische Produkte GmbH, 12277 Berlin Implantierbare Prothese
JP2561853B2 (ja) * 1988-01-28 1996-12-11 株式会社ジェイ・エム・エス 形状記憶性を有する成形体及びその使用方法
US4858603A (en) * 1988-06-06 1989-08-22 Johnson & Johnson Orthopaedics, Inc. Bone pin
US5444113A (en) * 1988-08-08 1995-08-22 Ecopol, Llc End use applications of biodegradable polymers
US5502158A (en) 1988-08-08 1996-03-26 Ecopol, Llc Degradable polymer composition
JPH0739506B2 (ja) * 1988-09-30 1995-05-01 三菱重工業株式会社 形状記憶ポリマー発泡体
US4938763B1 (en) * 1988-10-03 1995-07-04 Atrix Lab Inc Biodegradable in-situ forming implants and method of producing the same
US5633002A (en) * 1988-10-04 1997-05-27 Boehringer Ingelheim Gmbh Implantable, biodegradable system for releasing active substance
DE3936188A1 (de) 1988-11-01 1990-05-03 Boehringer Ingelheim Kg Kontinuierliches verfahren zur herstellung von resorbierbaren polyestern und deren verwendung
FI85223C (fi) * 1988-11-10 1992-03-25 Biocon Oy Biodegraderande kirurgiska implant och medel.
US5037178A (en) 1988-12-22 1991-08-06 Kingston Technologies, L.P. Amorphous memory polymer alignment device
FR2641692A1 (fr) * 1989-01-17 1990-07-20 Nippon Zeon Co Bouchon de fermeture d'une breche pour application medicale et dispositif pour bouchon de fermeture l'utilisant
US5522817A (en) * 1989-03-31 1996-06-04 United States Surgical Corporation Absorbable surgical fastener with bone penetrating elements
US5108755A (en) * 1989-04-27 1992-04-28 Sri International Biodegradable composites for internal medical use
DE59009894D1 (de) 1989-06-09 1996-01-04 Boehringer Ingelheim Kg Resorbierbare Formkörper und Verfahren zu ihrer Herstellung.
US5294395A (en) * 1989-09-01 1994-03-15 Ethicon, Inc. Thermal treatment of theraplastic filaments for the preparation of surgical sutures
US5201771A (en) * 1989-09-15 1993-04-13 Belykh Sergei I Endoprosthesis of the hip joint
US6908466B1 (en) * 1990-06-28 2005-06-21 Bonutti Ip, Llc Surgical devices having a biodegradable material with a therapeutic agent
IL94910A (en) 1990-06-29 1994-04-12 Technion Research Dev Foundati Biomedical adhesive compositions
US5047035A (en) 1990-08-10 1991-09-10 Mikhail Michael W E System for performing hip prosthesis revision surgery
US5201738A (en) * 1990-12-10 1993-04-13 Johnson & Johnson Orthopaedics, Inc. Biodegradable biocompatible anti-displacement device for prosthetic bone joints
CA2062012C (en) 1991-03-05 2003-04-29 Randall D. Ross Bioabsorbable interference bone fixation screw
DE4110316A1 (de) 1991-03-28 1992-10-01 Uwe Storch Verwendung einer mischung fuer die herstellung von medizinischen implantaten
ATE131373T1 (de) * 1991-05-24 1995-12-15 Synthes Ag Resorbierbare sehnen- und knochenverstärkungseinrichtung
EP0523926A3 (en) 1991-07-15 1993-12-01 Smith & Nephew Richards Inc Prosthetic implants with bioabsorbable coating
DE4226465C2 (de) 1991-08-10 2003-12-04 Gunze Kk Kieferknochen-reproduzierendes Material
US5275601A (en) * 1991-09-03 1994-01-04 Synthes (U.S.A) Self-locking resorbable screws and plates for internal fixation of bone fractures and tendon-to-bone attachment
US5500013A (en) 1991-10-04 1996-03-19 Scimed Life Systems, Inc. Biodegradable drug delivery vascular stent
US5360448A (en) 1991-10-07 1994-11-01 Thramann Jeffrey J Porous-coated bone screw for securing prosthesis
US5383931A (en) * 1992-01-03 1995-01-24 Synthes (U.S.A.) Resorbable implantable device for the reconstruction of the orbit of the human skull
FI95537C (fi) 1992-01-24 1996-02-26 Biocon Oy Kirurginen implantti
ES2125329T3 (es) 1992-02-14 1999-03-01 Smith & Nephew Inc Tornillos de materiales polimeros y recubrimientos para usos quirurgicos.
US5333624A (en) * 1992-02-24 1994-08-02 United States Surgical Corporation Surgical attaching apparatus
US5571193A (en) 1992-03-12 1996-11-05 Kampner; Stanley L. Implant with reinforced resorbable stem
AU4381793A (en) * 1992-05-20 1993-12-13 Cytrx Corporation Gel composition for implant prosthesis and method of use
DE4220216C1 (de) 1992-06-20 1994-01-13 S & G Implants Gmbh Endoprothese mit einem Stiel
BR9305661A (pt) * 1992-10-02 1996-11-26 Cargill Inc Pano de polímero de lactideo estável em fusao e processo para a sua fabricaçao
US5263991A (en) 1992-10-21 1993-11-23 Biomet, Inc. Method for heating biocompatible implants in a thermal packaging line
US5437918A (en) * 1992-11-11 1995-08-01 Mitsui Toatsu Chemicals, Inc. Degradable non-woven fabric and preparation process thereof
FR2701214B1 (fr) 1993-02-08 1998-07-31 Nippon Zeon Co Cathéter et procédé de fabrication de celui-ci.
US5441515A (en) * 1993-04-23 1995-08-15 Advanced Cardiovascular Systems, Inc. Ratcheting stent
US5716410A (en) * 1993-04-30 1998-02-10 Scimed Life Systems, Inc. Temporary stent and method of use
CA2127636C (en) 1993-07-21 2009-10-20 Cheng-Kung Liu Plasticizers for fibers used to form surgical devices
US6315788B1 (en) 1994-02-10 2001-11-13 United States Surgical Corporation Composite materials and surgical articles made therefrom
US5417712A (en) * 1994-02-17 1995-05-23 Mitek Surgical Products, Inc. Bone anchor
US5626861A (en) * 1994-04-01 1997-05-06 Massachusetts Institute Of Technology Polymeric-hydroxyapatite bone composite
WO1995034331A1 (en) 1994-06-10 1995-12-21 Ao-Forschungsinstitut Davos Self-expanding, adaptable cavity plug for use in implantation of endo-joint prosthesis
US6001101A (en) 1994-07-05 1999-12-14 Depuy France Screw device with threaded head for permitting the coaptation of two bone fragments
DE4424883A1 (de) 1994-07-14 1996-01-18 Merck Patent Gmbh Femurprothese
US5837276A (en) * 1994-09-02 1998-11-17 Delab Apparatus for the delivery of elongate solid drug compositions
FR2725617B1 (fr) 1994-10-12 1997-09-19 Prost Didier Tige femorale pour prothese de hanche
US5690671A (en) 1994-12-13 1997-11-25 Micro Interventional Systems, Inc. Embolic elements and methods and apparatus for their delivery
US5634936A (en) * 1995-02-06 1997-06-03 Scimed Life Systems, Inc. Device for closing a septal defect
IT1277799B1 (it) 1995-07-28 1997-11-12 Sanitaria Scaligera Spa Procedimento di funzionalizzazione superficiale di poliesteri- alifatici biocompatibili e bioassorbibili e poliesteri cosi' attivati
DE59608020D1 (de) * 1995-08-16 2001-11-29 Frank Lampe Endoprothese, insbesondere hüftgelenkprothese
FI98136C (fi) * 1995-09-27 1997-04-25 Biocon Oy Kudosolosuhteissa hajoava materiaali ja menetelmä sen valmistamiseksi
US6113624A (en) 1995-10-02 2000-09-05 Ethicon, Inc. Absorbable elastomeric polymer
US5716413A (en) * 1995-10-11 1998-02-10 Osteobiologics, Inc. Moldable, hand-shapable biodegradable implant material
US5856288A (en) 1996-04-26 1999-01-05 Nippon Shokubai Co., Ltd. Polyalkylene glycol-polyglyoxylate block copolymer, its production process and use
JP3731838B2 (ja) 1996-04-30 2006-01-05 株式会社クレハ ポリグリコール酸配向フィルム及びその製造方法
EP0806283B1 (de) 1996-05-09 2003-10-01 Kureha Kagaku Kogyo Kabushiki Kaisha Streckblasgeformter Behälter und Verfahren zu seiner Herstellung
US6143948A (en) 1996-05-10 2000-11-07 Isotis B.V. Device for incorporation and release of biologically active agents
US5670161A (en) 1996-05-28 1997-09-23 Healy; Kevin E. Biodegradable stent
AU2759397A (en) * 1996-05-28 1998-01-05 1218122 Ontario Inc. Resorbable implant biomaterial made of condensed calcium phosphate particles
US5935172A (en) 1996-06-28 1999-08-10 Johnson & Johnson Professional, Inc. Prosthesis with variable fit and strain distribution
US5756651A (en) * 1996-07-17 1998-05-26 Chronopol, Inc. Impact modified polylactide
BR9711214A (pt) * 1996-08-23 2000-01-11 Osteobiologics Inc Dispositivo e processo para medir uma propriedade de compressão de um material, e, processos para determinar a saúde ou doença de cartilagem e para fabricar o dispositivo.
JP3747563B2 (ja) 1996-10-18 2006-02-22 東レ株式会社 ポリ乳酸組成物およびその製造方法ならびに該組成物の成形品
US6258351B1 (en) 1996-11-06 2001-07-10 Shearwater Corporation Delivery of poly(ethylene glycol)-modified molecules from degradable hydrogels
US5893850A (en) * 1996-11-12 1999-04-13 Cachia; Victor V. Bone fixation device
GB2319475A (en) 1996-11-20 1998-05-27 Finsbury Bone augmenting implant
CA2274004A1 (en) * 1996-12-03 1998-06-11 Osteobiologics, Inc. Biodegradable polymeric film
FI965067A0 (fi) 1996-12-17 1996-12-17 Jvs Polymers Oy Implantmaterial som kan plastiseras
US5733330A (en) * 1997-01-13 1998-03-31 Advanced Cardiovascular Systems, Inc. Balloon-expandable, crush-resistant locking stent
SE512050C2 (sv) * 1997-01-21 2000-01-17 Nobel Biocare Ab Rotationssymmetriskt benförankringselement
US5997580A (en) 1997-03-27 1999-12-07 Johnson & Johnson Professional, Inc. Cement restrictor including shape memory material
US5810821A (en) * 1997-03-28 1998-09-22 Biomet Inc. Bone fixation screw system
US5977204A (en) 1997-04-11 1999-11-02 Osteobiologics, Inc. Biodegradable implant material comprising bioactive ceramic
JP4132089B2 (ja) * 1997-05-30 2008-08-13 オステオバイオロジックス，インコーポレイテッド 繊維強化多孔性生体分解性移植デバイス
US7524335B2 (en) 1997-05-30 2009-04-28 Smith & Nephew, Inc. Fiber-reinforced, porous, biodegradable implant device
US5980564A (en) 1997-08-01 1999-11-09 Schneider (Usa) Inc. Bioabsorbable implantable endoprosthesis with reservoir
US6001100A (en) 1997-08-19 1999-12-14 Bionx Implants Oy Bone block fixation implant
GB9717433D0 (en) 1997-08-19 1997-10-22 Univ Nottingham Biodegradable composites
US6013080A (en) * 1997-10-30 2000-01-11 Johnson & Johnson Professional, Inc. Tamp with horizontal steps used for impaction bone grafting in revision femur
SE510868C2 (sv) * 1997-11-03 1999-07-05 Artimplant Dev Artdev Ab Formkroppar för användning som implantat i humanmedicin samt förfarande för framställning av sådana formkroppar
US6135987A (en) 1997-12-22 2000-10-24 Kimberly-Clark Worldwide, Inc. Synthetic fiber
US6150497A (en) 1998-01-14 2000-11-21 Sherwood Services Ag Method for the production of polyglycolic acid
US6160084A (en) 1998-02-23 2000-12-12 Massachusetts Institute Of Technology Biodegradable shape memory polymers
US20020022588A1 (en) * 1998-06-23 2002-02-21 James Wilkie Methods and compositions for sealing tissue leaks
GB9814609D0 (en) 1998-07-07 1998-09-02 Smith & Nephew Polymers
JP2000117920A (ja) * 1998-08-11 2000-04-25 Dainippon Ink & Chem Inc 乳酸系ポリマ―積層体及び成形物
US6248430B1 (en) * 1998-08-11 2001-06-19 Dainippon Ink And Chemicals, Inc. Lactic acid-based polymer laminated product and molded product
SE515572C2 (sv) * 1998-09-09 2001-09-03 Lanka Ltd Implantat, sätt att framställa det och användning av det
JP2000085054A (ja) * 1998-09-14 2000-03-28 Daicel Chem Ind Ltd 崩壊性積層体およびその製造方法
US6248108B1 (en) * 1998-09-30 2001-06-19 Bionx Implants Oy Bioabsorbable surgical screw and washer system
US6162225A (en) 1998-10-26 2000-12-19 Musculoskeletal Transplant Foundation Allograft bone fixation screw method and apparatus
US6281262B1 (en) * 1998-11-12 2001-08-28 Takiron Co., Ltd. Shape-memory, biodegradable and absorbable material
US6283973B1 (en) 1998-12-30 2001-09-04 Depuy Orthopaedics, Inc. Strength fixation device
US6147135A (en) 1998-12-31 2000-11-14 Ethicon, Inc. Fabrication of biocompatible polymeric composites
US6293950B1 (en) 1999-01-15 2001-09-25 Luitpold Pharmaceuticals, Inc. Resorbable pin systems
CA2360904C (en) * 1999-02-04 2007-05-22 Michael Ahrens Bone screw
US6206883B1 (en) * 1999-03-05 2001-03-27 Stryker Technologies Corporation Bioabsorbable materials and medical devices made therefrom
ES2525553T3 (es) 1999-03-25 2014-12-26 Metabolix, Inc. Dispositivos y aplicaciones médicas de polímeros polihidroxialcanoato
US6187008B1 (en) * 1999-07-07 2001-02-13 Bristol-Myers Squibb Device for temporarily fixing bones
US7033603B2 (en) * 1999-08-06 2006-04-25 Board Of Regents The University Of Texas Drug releasing biodegradable fiber for delivery of therapeutics
EP1093774B1 (de) 1999-10-21 2002-06-19 Karl Storz GmbH & Co. KG Interferenzschraube
DE59901090D1 (de) * 1999-12-23 2002-05-02 Storz Karl Gmbh & Co Kg Schraube mit dezentralem Antrieb
US6423062B2 (en) * 2000-02-18 2002-07-23 Albert Enayati Bioabsorbable pin for external bone fixation
US6630153B2 (en) 2001-02-23 2003-10-07 Smith & Nephew, Inc. Manufacture of bone graft substitutes
US6425923B1 (en) * 2000-03-07 2002-07-30 Zimmer, Inc. Contourable polymer filled implant
AU2815001A (en) 2000-03-24 2001-09-27 Ethicon Inc. Thermoforming of absorbable medical devices
US6468277B1 (en) 2000-04-04 2002-10-22 Ethicon, Inc. Orthopedic screw and method
AU2001263223A1 (en) 2000-06-15 2001-12-24 Owens Corning Moldable matrix polymer material, molded composite product and method for makingsame
WO2002000137A1 (en) 2000-06-28 2002-01-03 Shukla Atul J Biodegradable vehicles and delivery systems of biologically active substances
AU2001282982B2 (en) * 2000-08-17 2007-01-04 Covidien Lp Sutures and coatings made from therapeutic absorbable glass
US6605090B1 (en) * 2000-10-25 2003-08-12 Sdgi Holdings, Inc. Non-metallic implant devices and intra-operative methods for assembly and fixation
US6719935B2 (en) * 2001-01-05 2004-04-13 Howmedica Osteonics Corp. Process for forming bioabsorbable implants
US6827743B2 (en) 2001-02-28 2004-12-07 Sdgi Holdings, Inc. Woven orthopedic implants
US6666868B2 (en) 2001-03-02 2003-12-23 Medicinelodge, Inc. Two-part orthopedic fastener
US7267288B2 (en) 2001-03-22 2007-09-11 Nevada Supply Corporation Polyurethane in intimate contact with fibrous material
US20040265385A1 (en) 2001-04-12 2004-12-30 Therics, Inc. Porous biostructure partially occupied by interpenetrant and method for making same
US6471707B1 (en) 2001-05-11 2002-10-29 Biomet Bone screw having bioresorbable proximal shaft portion
GB0115320D0 (en) 2001-06-22 2001-08-15 Univ Nottingham Matrix
GB0116341D0 (en) 2001-07-04 2001-08-29 Smith & Nephew Biodegradable polymer systems
US6749639B2 (en) * 2001-08-27 2004-06-15 Mayo Foundation For Medical Education And Research Coated prosthetic implant
US6841111B2 (en) * 2001-08-31 2005-01-11 Basf Corporation Method for making a polyurea-polyurethane composite structure substantially free of volatile organic compounds
US6916321B2 (en) * 2001-09-28 2005-07-12 Ethicon, Inc. Self-tapping resorbable two-piece bone screw
US20030125745A1 (en) * 2001-11-05 2003-07-03 Bio One Tech Inc. Bone-fixing device
CN1301757C (zh) 2001-11-27 2007-02-28 多喜兰株式会社 植入物材料及其生产方法
JP2005514157A (ja) * 2001-12-21 2005-05-19 スミス アンド ネフュー インコーポレーテッド ヒンジ式関節システム
GB0202233D0 (en) * 2002-01-31 2002-03-20 Smith & Nephew Bioresorbable polymers
WO2003080119A1 (en) * 2002-03-26 2003-10-02 Yissum Research Development Company Of The Hebrew University Of Jerusalem Responsive biomedical composites
US7261734B2 (en) * 2002-04-23 2007-08-28 Boston Scientific Scimed, Inc. Resorption-controllable medical implants
US7166133B2 (en) 2002-06-13 2007-01-23 Kensey Nash Corporation Devices and methods for treating defects in the tissue of a living being
US6981991B2 (en) * 2002-06-27 2006-01-03 Ferree Bret A Arthroplasty devices configured to reduce shear stress
DE60325742D1 (de) 2002-07-31 2009-02-26 Alza Corp Injizierbare multimodale polymere depotzusammensetzungen und ihre verwendungen
US7270813B2 (en) 2002-10-08 2007-09-18 Osteotech, Inc. Coupling agents for orthopedic biomaterials
US7291345B2 (en) * 2002-12-12 2007-11-06 Osteotech, Inc. Formable and settable polymer bone composite and method of production thereof
EP1433489A1 (de) * 2002-12-23 2004-06-30 Degradable Solutions AG Biologisch abbaubares, poröses Knochenimplantat mit integrierter Abdeckmembrane
US20050013793A1 (en) * 2003-01-16 2005-01-20 Beckman Eric J. Biodegradable polyurethanes and use thereof
US20040260398A1 (en) 2003-02-10 2004-12-23 Kelman David C. Resorbable devices
US20040156878A1 (en) * 2003-02-11 2004-08-12 Alireza Rezania Implantable medical device seeded with mammalian cells and methods of treatment
US20070043376A1 (en) * 2003-02-21 2007-02-22 Osteobiologics, Inc. Bone and cartilage implant delivery device
AU2004216201B2 (en) 2003-02-21 2010-12-23 Osteobiologics, Inc. Bone and cartilage implant delivery device
US20060178748A1 (en) * 2004-02-05 2006-08-10 Dinger Fred B Iii Implants and delivery system for treating defects in articulating surfaces
GB0307011D0 (en) 2003-03-27 2003-04-30 Regentec Ltd Porous matrix
US7300439B2 (en) 2003-06-24 2007-11-27 Depuy Mitek, Inc. Porous resorbable graft fixation pin
GB0317192D0 (en) 2003-07-19 2003-08-27 Smith & Nephew High strength bioresorbable co-polymers
JP4251061B2 (ja) * 2003-10-03 2009-04-08 ブリヂストンスポーツ株式会社 ゴルフクラブヘッド
GB0329654D0 (en) 2003-12-23 2004-01-28 Smith & Nephew Tunable segmented polyacetal
AU2005206920B2 (en) * 2004-01-16 2011-04-14 Osteobiologics, Inc. Bone-tendon-bone implant
EP1729674A4 (de) * 2004-02-05 2011-01-26 Osteobiologics Inc Saugfähige orthopädische implantate
EP1720926A1 (de) 2004-03-03 2006-11-15 Commonwealth Scientific And Industrial Research Organisation Polymerzusammensetzungen zur dual- oder mehrstufenhärtung
CA2555586A1 (en) 2004-03-09 2005-09-22 Osteobiologics, Inc. Implant scaffold combined with autologous or allogenic tissue
US20060067971A1 (en) * 2004-09-27 2006-03-30 Story Brooks J Bone void filler
FI122108B (fi) 2004-11-17 2011-08-31 Jvs Polymers Oy Silloittuva biopolymeeri
ITPD20040312A1 (it) 2004-12-15 2005-03-15 Fidia Advanced Biopolymers Srl Protesi e o supporto per la sostituzione, riparazione, rigenerazione del menisco
US7772352B2 (en) * 2005-01-28 2010-08-10 Bezwada Biomedical Llc Bioabsorbable and biocompatible polyurethanes and polyamides for medical devices
WO2006083946A2 (en) * 2005-02-01 2006-08-10 Osteobiologics, Inc. Method and device for selective addition of a bioactive agent to a multi-phase implant
US20060200150A1 (en) 2005-03-01 2006-09-07 Jouko Ilomaki Bone screw and driver system
US7963287B2 (en) 2005-04-28 2011-06-21 Boston Scientific Scimed, Inc. Tissue-treatment methods
JP2009504929A (ja) 2005-08-18 2009-02-05 スミス アンド ネフュー ピーエルシー 高強度デバイス及び複合材料
JP2009511092A (ja) 2005-08-18 2009-03-19 スミス アンド ネフュー ピーエルシー マルチモーダル高強度デバイス及び複合材料
CA2630661A1 (en) 2005-11-29 2007-06-07 Indiana University Research And Technology Corporation Biodegradable implant ploymers and composites
WO2007067625A2 (en) * 2005-12-06 2007-06-14 Tyco Healthcare Group Lp Bioabsorbable surgical composition
DE602006020063D1 (de) * 2005-12-07 2011-03-24 Univ Ramot Wirkstoffabgebende verbundkörper
CA2637606C (en) 2006-01-19 2013-03-19 Osteotech, Inc. Porous osteoimplant
EP1976460A4 (de) * 2006-01-19 2012-06-20 Warsaw Orthopedic Inc Injizierbare und formbare knochenersatzmaterialien
US7594874B2 (en) 2006-04-12 2009-09-29 Meissner Richard K Quick connect climbing hold

Also Published As

Publication number Publication date
US20040242722A1 (en) 2004-12-02
GB0116341D0 (en) 2001-08-29
CA2452358C (en) 2010-05-04
ES2374555T3 (es) 2012-02-17
JP2004533308A (ja) 2004-11-04
EP1401510B1 (de) 2011-10-05
EP1401510A1 (de) 2004-03-31
US7524891B2 (en) 2009-04-28
AU2002310552B2 (en) 2007-12-13
WO2003004071A1 (en) 2003-01-16
CA2452358A1 (en) 2003-01-16

Similar Documents

Publication Publication Date Title
ATE527000T1 (de) Bioabbaubares polymersystem
DE60222415D1 (de) Resorbierbare polymerzusammensetzungen
PT1061900E (pt) Composicoes e metodos para libertacao de uma droga
ATE297954T1 (de) Polymere mit uniformem molekulargewicht
ES2173999T3 (es) Dispersante de cemento, metodo para la produccion del mismo y composicion de cemento que utiliza el dispersante.
DE69412250D1 (de) Pyridobismidazole enthaltendes rigid-rod-Polymer
ATE218154T1 (de) Physikalisch modifizierte abbaubare thermoplastische zusammensetzung
DE69914787D1 (de) Flüssige zusammensetzungen mit kontrollierter freigabe mit niedrigem initialfreisetzungsstoss des wirkstoffs
NO962040L (no) Mikroinnkapslede 3-piperidinyl-substituerte 1,2-benzisoksazoler og 1,2-benzisotiazoler
BR9508409A (pt) Composição de peróxido transportável estável em armazenagem e uso de uma formulação de peróxido orgânico
NO20005462L (no) Nye fettsyreanaloger for behandling av diabetes
DE69408527D1 (de) Makromolekulare mikropartikel und verfahren zu ihrer herstellung
MXPA03008886A (es) Composiciones de baja respuesta glicemica.
NO20041459L (no) Kopolymerer for gelatinering av syrer
MXPA05011584A (es) Derivados de polilacturo ramificados, biodegradables capaces de formar micelas polimericas, y su metodo de preparacion y uso.
EP1016638A3 (de) Zementzusatzstoff, Zementzusammensetzung und polymere Polycarbonsäure
SE0201659D0 (sv) Modified release pharmaceutical formulation
DK0945405T3 (da) Hårhedsstabiliserende percarboxylsyreopløsninger, fremgangsmåder til fremstilling deraf og anvendelse deraf
AU2003210404A1 (en) Stabiliser combinations for polymer systems
ATE433470T1 (de) Gegenüber ionisierender strahlung stabile polyarylestercarbonatzusammensetzungen
DE50210465D1 (de) Stabilisierte thermoplastische formmassen
EA200300838A1 (ru) Композиция стабилизаторов для галогенированных полимеров, ее применение и полимеры, содержащие такие композиции
NO996212L (no) Polymerblanding med høy transparens
TR199802040T2 (xx) Aspartik asit i�erikli polimerlerin so�utma devrelerinde kullan�m�.
BR0015092A (pt) Produtos de polìmero compreendendo composições de copolìmero de polihidróxialcanoato biodegradáveis elásticas e macias e métodos para preparação de tais produtos de polìmeros

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties