ATE297940T1 - Arylphosphatderivate von d4t - Google Patents
Arylphosphatderivate von d4tInfo
- Publication number
- ATE297940T1 ATE297940T1 AT00991478T AT00991478T ATE297940T1 AT E297940 T1 ATE297940 T1 AT E297940T1 AT 00991478 T AT00991478 T AT 00991478T AT 00991478 T AT00991478 T AT 00991478T AT E297940 T1 ATE297940 T1 AT E297940T1
- Authority
- AT
- Austria
- Prior art keywords
- derivatives
- aryl phosphate
- group
- aryl
- nucleoside derivatives
- Prior art date
Links
- -1 aryl phosphate nucleoside derivatives Chemical class 0.000 abstract 4
- 229910019142 PO4 Inorganic materials 0.000 abstract 2
- 125000003118 aryl group Chemical group 0.000 abstract 2
- 239000010452 phosphate Substances 0.000 abstract 2
- 108010078851 HIV Reverse Transcriptase Proteins 0.000 abstract 1
- OAICVXFJPJFONN-UHFFFAOYSA-N Phosphorus Chemical compound [P] OAICVXFJPJFONN-UHFFFAOYSA-N 0.000 abstract 1
- 125000000539 amino acid group Chemical group 0.000 abstract 1
- 230000001472 cytotoxic effect Effects 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 239000003112 inhibitor Substances 0.000 abstract 1
- 125000002467 phosphate group Chemical group [H]OP(=O)(O[H])O[*] 0.000 abstract 1
- 229910052698 phosphorus Inorganic materials 0.000 abstract 1
- 239000011574 phosphorus Substances 0.000 abstract 1
- 230000003389 potentiating effect Effects 0.000 abstract 1
- 125000001424 substituent group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/06—Pyrimidine radicals
- C07H19/10—Pyrimidine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/655—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms
- C07F9/65515—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms the oxygen atom being part of a five-membered ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6558—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system
- C07F9/65586—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system at least one of the hetero rings does not contain nitrogen as ring hetero atom
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Communicable Diseases (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Virology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Dental Preparations (AREA)
- Luminescent Compositions (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/US2000/042132 WO2002038576A1 (en) | 2000-11-13 | 2000-11-13 | ARYL PHOSPHATE DERIVATIVES OF d4T |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE297940T1 true ATE297940T1 (de) | 2005-07-15 |
Family
ID=21742203
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT00991478T ATE297940T1 (de) | 2000-11-13 | 2000-11-13 | Arylphosphatderivate von d4t |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US20050277620A1 (de) |
| EP (1) | EP1334108B1 (de) |
| JP (1) | JP2004513177A (de) |
| AT (1) | ATE297940T1 (de) |
| AU (1) | AU2001232701A1 (de) |
| CA (1) | CA2428808A1 (de) |
| DE (1) | DE60020891T2 (de) |
| DK (1) | DK1334108T3 (de) |
| ES (1) | ES2240234T3 (de) |
| PT (1) | PT1334108E (de) |
| WO (1) | WO2002038576A1 (de) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7144874B2 (en) * | 2002-10-25 | 2006-12-05 | Parker Hughes Institute | Aryl phosphate derivatives of d4T having activity against resistant HIV strains |
| US20030236218A1 (en) * | 2002-06-12 | 2003-12-25 | Uckun Fatih M. | Aryl phosphate derivatives of d4T with selective activity against adenovirus and HIV |
| US11628598B2 (en) | 2021-01-05 | 2023-04-18 | Richard Sofia | Systems and method for manufacturing pellets from mixed plastics |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4707362A (en) * | 1985-02-15 | 1987-11-17 | Biotek, Inc. | Sustained release composition |
| US4841039A (en) * | 1986-05-01 | 1989-06-20 | Emory University | 2',3'-dideoxy-5-substituted uridines and related compounds as antiviral agents |
| US4983393A (en) * | 1987-07-21 | 1991-01-08 | Maximed Corporation | Intra-vaginal device and method for sustained drug release |
| ZA947572B (en) * | 1993-09-29 | 1995-09-28 | Hampton Roads Medical College | Contraceptive compositions |
| US5672698A (en) * | 1993-11-15 | 1997-09-30 | Bristol-Myers Squibb Co. | Preparation of 2',3'-didehydro-3'-deoxythymidine from 5-methyluridine |
| US5659023A (en) * | 1995-02-01 | 1997-08-19 | Gilead Sciences, Inc. | Nucleotide analogues |
| GB9505025D0 (en) * | 1995-03-13 | 1995-05-03 | Medical Res Council | Chemical compounds |
| US7144874B2 (en) * | 2002-10-25 | 2006-12-05 | Parker Hughes Institute | Aryl phosphate derivatives of d4T having activity against resistant HIV strains |
| US6030957A (en) * | 1998-06-29 | 2000-02-29 | Wayne Hughes Institute | Aryl phosphate derivatives of d4T having anti-HIV activity |
-
2000
- 2000-11-13 AT AT00991478T patent/ATE297940T1/de not_active IP Right Cessation
- 2000-11-13 AU AU2001232701A patent/AU2001232701A1/en not_active Abandoned
- 2000-11-13 DE DE60020891T patent/DE60020891T2/de not_active Expired - Fee Related
- 2000-11-13 DK DK00991478T patent/DK1334108T3/da active
- 2000-11-13 EP EP00991478A patent/EP1334108B1/de not_active Expired - Lifetime
- 2000-11-13 PT PT00991478T patent/PT1334108E/pt unknown
- 2000-11-13 CA CA002428808A patent/CA2428808A1/en not_active Abandoned
- 2000-11-13 JP JP2002541108A patent/JP2004513177A/ja not_active Withdrawn
- 2000-11-13 ES ES00991478T patent/ES2240234T3/es not_active Expired - Lifetime
- 2000-11-13 WO PCT/US2000/042132 patent/WO2002038576A1/en not_active Ceased
-
2003
- 2003-05-12 US US10/435,897 patent/US20050277620A1/en not_active Abandoned
-
2005
- 2005-12-09 US US11/275,102 patent/US20060293285A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| CA2428808A1 (en) | 2002-05-16 |
| US20060293285A1 (en) | 2006-12-28 |
| EP1334108B1 (de) | 2005-06-15 |
| JP2004513177A (ja) | 2004-04-30 |
| ES2240234T3 (es) | 2005-10-16 |
| AU2001232701A1 (en) | 2002-05-21 |
| US20050277620A1 (en) | 2005-12-15 |
| EP1334108A1 (de) | 2003-08-13 |
| PT1334108E (pt) | 2005-08-31 |
| DE60020891D1 (de) | 2005-07-21 |
| DE60020891T2 (de) | 2005-12-08 |
| WO2002038576A1 (en) | 2002-05-16 |
| DK1334108T3 (da) | 2005-07-11 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
Ref document number: 1334108 Country of ref document: EP |
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| REN | Ceased due to non-payment of the annual fee |