ATE297940T1 - Arylphosphatderivate von d4t - Google Patents

Arylphosphatderivate von d4t

Info

Publication number: ATE297940T1
Authority: AT; Austria
Prior art keywords: derivatives; aryl phosphate; group; aryl; nucleoside derivatives
Prior art date: 2000-11-13

Application number

AT00991478T

Other languages

English (en)

Inventor

Fatih M Uckun

Original Assignee

Parker Hughes Inst

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-11-13

Filing date

2000-11-13

Publication date

2005-07-15

2000-11-13 Application filed by Parker Hughes Inst filed Critical Parker Hughes Inst

2005-07-15 Application granted granted Critical

2005-07-15 Publication of ATE297940T1 publication Critical patent/ATE297940T1/de

Links

-1 aryl phosphate nucleoside derivatives Chemical class 0.000 abstract 4
229910019142 PO4 Inorganic materials 0.000 abstract 2
125000003118 aryl group Chemical group 0.000 abstract 2
239000010452 phosphate Substances 0.000 abstract 2
108010078851 HIV Reverse Transcriptase Proteins 0.000 abstract 1
OAICVXFJPJFONN-UHFFFAOYSA-N Phosphorus Chemical compound [P] OAICVXFJPJFONN-UHFFFAOYSA-N 0.000 abstract 1
125000000539 amino acid group Chemical group 0.000 abstract 1
230000001472 cytotoxic effect Effects 0.000 abstract 1
230000000694 effects Effects 0.000 abstract 1
239000003112 inhibitor Substances 0.000 abstract 1
125000002467 phosphate group Chemical group [H]OP(=O)(O[H])O[*] 0.000 abstract 1
229910052698 phosphorus Inorganic materials 0.000 abstract 1
239000011574 phosphorus Substances 0.000 abstract 1
230000003389 potentiating effect Effects 0.000 abstract 1
125000001424 substituent group Chemical group 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/06—Pyrimidine radicals
- C07H19/10—Pyrimidine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/655—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms
- C07F9/65515—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms the oxygen atom being part of a five-membered ring
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6558—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system
- C07F9/65586—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system at least one of the hetero rings does not contain nitrogen as ring hetero atom

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Biochemistry (AREA)
Molecular Biology (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Genetics & Genomics (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Engineering & Computer Science (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Biotechnology (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Virology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Dental Preparations (AREA)
Luminescent Compositions (AREA)
Saccharide Compounds (AREA)

AT00991478T 2000-11-13 2000-11-13 Arylphosphatderivate von d4t ATE297940T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
PCT/US2000/042132 WO2002038576A1 (en)	2000-11-13	2000-11-13	ARYL PHOSPHATE DERIVATIVES OF d4T

Publications (1)

Publication Number	Publication Date
ATE297940T1 true ATE297940T1 (de)	2005-07-15

Family

ID=21742203

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT00991478T ATE297940T1 (de)	2000-11-13	2000-11-13	Arylphosphatderivate von d4t

Country Status (11)

Country	Link
US (2)	US20050277620A1 (de)
EP (1)	EP1334108B1 (de)
JP (1)	JP2004513177A (de)
AT (1)	ATE297940T1 (de)
AU (1)	AU2001232701A1 (de)
CA (1)	CA2428808A1 (de)
DE (1)	DE60020891T2 (de)
DK (1)	DK1334108T3 (de)
ES (1)	ES2240234T3 (de)
PT (1)	PT1334108E (de)
WO (1)	WO2002038576A1 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US7144874B2 (en) *	2002-10-25	2006-12-05	Parker Hughes Institute	Aryl phosphate derivatives of d4T having activity against resistant HIV strains
US20030236218A1 (en) *	2002-06-12	2003-12-25	Uckun Fatih M.	Aryl phosphate derivatives of d4T with selective activity against adenovirus and HIV
US11628598B2 (en)	2021-01-05	2023-04-18	Richard Sofia	Systems and method for manufacturing pellets from mixed plastics

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4707362A (en) *	1985-02-15	1987-11-17	Biotek, Inc.	Sustained release composition
US4841039A (en) *	1986-05-01	1989-06-20	Emory University	2',3'-dideoxy-5-substituted uridines and related compounds as antiviral agents
US4983393A (en) *	1987-07-21	1991-01-08	Maximed Corporation	Intra-vaginal device and method for sustained drug release
ZA947572B (en) *	1993-09-29	1995-09-28	Hampton Roads Medical College	Contraceptive compositions
US5672698A (en) *	1993-11-15	1997-09-30	Bristol-Myers Squibb Co.	Preparation of 2',3'-didehydro-3'-deoxythymidine from 5-methyluridine
US5659023A (en) *	1995-02-01	1997-08-19	Gilead Sciences, Inc.	Nucleotide analogues
GB9505025D0 (en) *	1995-03-13	1995-05-03	Medical Res Council	Chemical compounds
US6030957A (en) *	1998-06-29	2000-02-29	Wayne Hughes Institute	Aryl phosphate derivatives of d4T having anti-HIV activity
US7144874B2 (en) *	2002-10-25	2006-12-05	Parker Hughes Institute	Aryl phosphate derivatives of d4T having activity against resistant HIV strains

2000
- 2000-11-13 DK DK00991478T patent/DK1334108T3/da active
- 2000-11-13 AU AU2001232701A patent/AU2001232701A1/en not_active Abandoned
- 2000-11-13 DE DE60020891T patent/DE60020891T2/de not_active Expired - Fee Related
- 2000-11-13 WO PCT/US2000/042132 patent/WO2002038576A1/en not_active Ceased
- 2000-11-13 AT AT00991478T patent/ATE297940T1/de not_active IP Right Cessation
- 2000-11-13 JP JP2002541108A patent/JP2004513177A/ja not_active Withdrawn
- 2000-11-13 EP EP00991478A patent/EP1334108B1/de not_active Expired - Lifetime
- 2000-11-13 PT PT00991478T patent/PT1334108E/pt unknown
- 2000-11-13 CA CA002428808A patent/CA2428808A1/en not_active Abandoned
- 2000-11-13 ES ES00991478T patent/ES2240234T3/es not_active Expired - Lifetime
2003
- 2003-05-12 US US10/435,897 patent/US20050277620A1/en not_active Abandoned
2005
- 2005-12-09 US US11/275,102 patent/US20060293285A1/en not_active Abandoned

Also Published As

Publication number	Publication date
CA2428808A1 (en)	2002-05-16
EP1334108B1 (de)	2005-06-15
DK1334108T3 (da)	2005-07-11
US20050277620A1 (en)	2005-12-15
DE60020891T2 (de)	2005-12-08
EP1334108A1 (de)	2003-08-13
JP2004513177A (ja)	2004-04-30
US20060293285A1 (en)	2006-12-28
AU2001232701A1 (en)	2002-05-21
ES2240234T3 (es)	2005-10-16
WO2002038576A1 (en)	2002-05-16
PT1334108E (pt)	2005-08-31
DE60020891D1 (de)	2005-07-21

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2006-03-15

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2007-02-15

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