ATE297945T1 - Glutathionderivate und dazugehörige dosisformen - Google Patents

Glutathionderivate und dazugehörige dosisformen

Info

Publication number
ATE297945T1
ATE297945T1 AT99914763T AT99914763T ATE297945T1 AT E297945 T1 ATE297945 T1 AT E297945T1 AT 99914763 T AT99914763 T AT 99914763T AT 99914763 T AT99914763 T AT 99914763T AT E297945 T1 ATE297945 T1 AT E297945T1
Authority
AT
Austria
Prior art keywords
alkyl group
group
dosage forms
alkenyl group
derivative
Prior art date
Application number
AT99914763T
Other languages
English (en)
Inventor
Kiyoyuki Sakon
Yoshimitsu Naniwa
Mitsuru Kobayashi
Daishiro Miura
Hiroshi Imai
Atsushi Imaizumi
Original Assignee
Teijin Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Teijin Ltd filed Critical Teijin Ltd
Application granted granted Critical
Publication of ATE297945T1 publication Critical patent/ATE297945T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/0215—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing natural amino acids, forming a peptide bond via their side chain functional group, e.g. epsilon-Lys, gamma-Glu
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)
AT99914763T 1998-04-16 1999-04-16 Glutathionderivate und dazugehörige dosisformen ATE297945T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP10635998 1998-04-16
PCT/JP1999/002044 WO1999054346A1 (en) 1998-04-16 1999-04-16 Glutathione derivatives and dosage forms thereof

Publications (1)

Publication Number Publication Date
ATE297945T1 true ATE297945T1 (de) 2005-07-15

Family

ID=14431564

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99914763T ATE297945T1 (de) 1998-04-16 1999-04-16 Glutathionderivate und dazugehörige dosisformen

Country Status (10)

Country Link
US (2) US6627732B1 (de)
EP (1) EP1072608B1 (de)
JP (1) JP4059627B2 (de)
KR (1) KR20010042752A (de)
AT (1) ATE297945T1 (de)
AU (1) AU766515B2 (de)
CA (1) CA2328731A1 (de)
DE (1) DE69925824D1 (de)
TW (1) TW576838B (de)
WO (1) WO1999054346A1 (de)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7029695B2 (en) 2001-07-10 2006-04-18 Telik, Inc. Therapeutic compositions containing glutathione analogs
US6747009B2 (en) * 2002-09-19 2004-06-08 Universiteit Leiden Peptidomimetic glutathione analogs
US8198247B2 (en) * 2004-12-21 2012-06-12 Telik, Inc. Process for and intermediates in the preparation of canfosfamide and its salts
CN101090977B (zh) * 2005-01-06 2013-04-10 泰立克公司 三肽和四肽硫醚
US8067380B2 (en) 2005-12-19 2011-11-29 Industrial Technology Research Institute Glutathione-based delivery system
US7446096B2 (en) * 2005-12-19 2008-11-04 Industrial Technology Research Institute Glutathione based delivery system
JP5333970B2 (ja) * 2007-03-20 2013-11-06 国立大学法人大阪大学 心筋梗塞の予防および／または治療薬
ES2322121B1 (es) * 2007-12-10 2010-04-19 Consejo Superior De Investigaciones Cientificas Nuevos derivados de aminoacidos dicarboxilicos y su aplicacion en el tratamiento de enfermedades neurodegenerativas.
US8580742B2 (en) * 2010-03-05 2013-11-12 N.V. Perricone Llc Topical glutathione formulations for menopausal skin
US20110160144A1 (en) * 2009-12-28 2011-06-30 Perricone Nicholas V Topical Acyl Glutathione Formulations
US8609604B2 (en) 2009-12-28 2013-12-17 N.V. Perricone Llc Methods of improving the appearance of aging skin
WO2011156045A2 (en) * 2010-06-07 2011-12-15 Telik, Inc. Tablet formulation of ezatiostat
CN102939300A (zh) 2010-06-07 2013-02-20 泰立克公司 无溶剂化晶体依泽替米贝盐酸盐d型的制备
US20140315975A1 (en) 2011-06-21 2014-10-23 Nitto Denko Corporation Apoptosis-inducing agent
US20140120157A1 (en) * 2012-09-19 2014-05-01 Georgetown University Targeted liposomes
JP6340162B2 (ja) 2012-12-20 2018-06-06 日東電工株式会社 アポトーシス誘導剤
JP6727765B2 (ja) 2014-06-17 2020-07-22 日東電工株式会社 アポトーシス誘導剤
US10264976B2 (en) 2014-12-26 2019-04-23 The University Of Akron Biocompatible flavonoid compounds for organelle and cell imaging
RU2692065C1 (ru) * 2018-04-05 2019-06-20 федеральное государственное автономное образовательное учреждение высшего образования "Казанский (Приволжский) федеральный университет" (ФГАОУ ВО КФУ) Глутатионаммониевые соли o,o-диорганилдитиофосфорных кислот, обладающие антиоксидантной и противоопухолевой активностью
EP4365289A3 (de) 2018-11-16 2024-07-10 Nitto Denko Corporation Rna-interferenz-freisetzungsformulierung und verfahren für maligne tumore
US11419849B1 (en) 2019-02-06 2022-08-23 Kitt Bio, Inc. Methods and products for adverse effects of air travel, jet lag, or a change to a sleep wake timing cycle
EP3973991A4 (de) 2019-05-14 2023-07-05 Keio University Anti-tumormittel und kompoundierungsmittel

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995005863A1 (en) * 1993-08-27 1995-03-02 St. Paul Medical, Inc. Needleless iv medical delivery system
JPH11507056A (ja) 1995-06-07 1999-06-22 テラピン テクノロジーズ、インク． グルタチオンアナログの代謝的効果
AU2226599A (en) 1998-01-21 1999-08-09 Telik, Inc. Methods to identify myelostimulants
PT1143992E (pt) 1999-01-27 2005-05-31 Telik Inc Composicoes farmaceuticas contendo analogos de glutationa

Also Published As

Publication number Publication date
CA2328731A1 (en) 1999-10-28
US6627732B1 (en) 2003-09-30
AU766515B2 (en) 2003-10-16
EP1072608A4 (de) 2001-09-19
DE69925824D1 (de) 2005-07-21
US20040018985A1 (en) 2004-01-29
KR20010042752A (ko) 2001-05-25
EP1072608A1 (de) 2001-01-31
EP1072608B1 (de) 2005-06-15
TW576838B (en) 2004-02-21
WO1999054346A1 (en) 1999-10-28
JP4059627B2 (ja) 2008-03-12
AU3344599A (en) 1999-11-08

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Legal Events

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RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties